Basic Information

Insect: Drosophila robusta
Gene Symbol: -
Assembly: GCA_004143805.1
Location: SCDV01000325.1:23393-25688[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 2.5e-05 0.0031 18.5 2.5 1 23 425 447 425 447 0.97

2 7 5.3e-05 0.0067 17.4 0.3 1 23 453 476 453 476 0.97

3 7 0.19 23 6.3 1.4 1 23 482 505 482 505 0.92

4 7 9.3e-05 0.012 16.6 4.8 1 23 544 566 544 566 0.95

5 7 0.00038 0.048 14.7 1.5 1 23 572 594 572 594 0.97

6 7 0.00011 0.014 16.4 0.4 1 23 600 622 600 622 0.98

7 7 0.0019 0.24 12.5 3.1 1 22 628 649 628 652 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	2.5e-05	0.0031	18.5	2.5	1	23	425	447	425	447	0.97
2	7	5.3e-05	0.0067	17.4	0.3	1	23	453	476	453	476	0.97
3	7	0.19	23	6.3	1.4	1	23	482	505	482	505	0.92
4	7	9.3e-05	0.012	16.6	4.8	1	23	544	566	544	566	0.95
5	7	0.00038	0.048	14.7	1.5	1	23	572	594	572	594	0.97
6	7	0.00011	0.014	16.4	0.4	1	23	600	622	600	622	0.98
7	7	0.0019	0.24	12.5	3.1	1	22	628	649	628	652	0.91

Sequence Information

Coding Sequence: atgaagTGTGCGGTCCAAAACtgtggcaacaaatttaaagcgcGTCAAAAACATTCGAAACAGCTGAGTTTCTTTAGCTTTCCAAAAAATccggatatcttgaaaaaatgGATTTCATTTTGccgcaaaagcaacaaagagAAGCTGAGGGCACCTCAAAAGAGCGTCATTTGCAATGAGCACTTTAAAGAGGAAGACATCCAAGGAGGATTACAATTCCAAATGGGCTTGTGCTCAAAGCGAACGCTTAGACCGGGCGCCGTGCcgtgcataaacaaaaacgacGTAAGTGCGATCGAACGAGAGCGTTCGGAAAAGCGAAATAACAAGAAGTTGGTCGCCGAGCTGCTCGAGGAAGCTGCCGCACGCGAAGCAGCGGAAGCCAGCGGAGCAATTGTTATAGCACCCGACTTTATCAGGAACACGGGCATTGTCTCAGTGCCCGACTTTGTTAGCGCCACCGGAAATGCCTTTATTCCATTCACACCGACGCCCAGTGAAAGTGATCCCTTAGCCGAGGAACAGGCGGAACTGGACGTGAGCACAAAGAGTGGCCAAGATGACAGCAATATTAATCAGCAAAAGTGTCGCACCTGCCATgaactttttgctgttgatgACAATGCTAAAGATCTGTGCGACGAGCAAAACGCCGTAATGTTATATCACATCGAAGTTATTACCGGCATTTGGATCCAGTGCAAAGACGGCATGTCACCGTTTATGTGTCCAAGCTGCGTCCGTAATCTCCGCACAGCCATTGAATTCCGAGAGACATGCATACAAACCGAACTACATCTGGCTGGGAGCACTGTTGATATCCTTCCAGTTGTTATTAAGGAAAACGATTCAGAACCCTGGGTTGCACCGGATTCCCAGGATGGCCAGGAGCTGCTGCAAATAAGTGAGGATATTGTCAAAGAGGAGTATGTTTCTGTGTTTCCGGCAGAAGCCCAGAATGGTCAAACAACTGTTGTTGAGCCTTTGTccgtggcaacagcagcacaaaaaacaattgaggCCATAAATCCACCGGGTGCAGACCCCGAAAGTCTTGCACTGGGCGCCCAAATCTATGAGGACCTTTTAAACGAATATCGCGGTAAGGACAAGACACCACGTCCAAGACAACGAAAAGTAACAATAAACAGGACAAAATCGGCAAGACAGAGGAAACGTAAGCCGCGGGAACCAAAACCGAAACGTCCGAAACGCACGAAAGAGGAAAGGAATCGCATCCGCCGTGAACAGATCAGAGCCATGCCGCTCAATCATGTGTGCGACCAGTGCGGCGCCTCCTTTCGTGTTCGCTGTAATTTAACCATACACATGTTGcgtcacacacgcacaaagaACTATCCCTGCTCCGAGTGCCCCAAGAAGTTCTACGATGCCTACATGCGAAATATTCACATCCGTGTGCGCCACAGAGGCGAACTGCCATTTGCCTGCAATTTTTGCCGAAAAGCCTTTGGCTCGTCCAACACTCGTTATCTGCACGAAAAAAAAGTTCACGGAGCAACTCCGCGTATTCATAGGAACGCTAGTCGCTTGAACAAACGAATCGAACTGAAGGAGCAGCAGACGGAACTGACACTGGAAGAGCAGGAACAAAAGGCAAACTTGCGTCATTTTTGCACATATTGCGATAAGAGCTATGCAACAAAATATGCACTAAATTGGCATACCAATCATCACACCGGTGTTACGCCCTTTAAATGCAAGCTCTGTGATACGACCTTTGCGGATCCCCAGTCGAAAAAGAAGCACGAGATGCAGCACGACAGTAAACGTCCCTACGAGTGCGACATCTGTCTGAAGGGCTTCTATGTGCGCAGCAAGCTGCGGGAACATGAACGAATTCATACCGGAGAACGTCCCTATAGGTGTGATGTTTGCAACGCTTTCTTTCGATACAAGTTTAACTTATACTCGCATCAGTTTAGTAAAATGCATAAGGAGAATCTCCGGAAGCCGACTAAGATTGAAGTTAGCGAcgaatcaaattga
Protein Sequence: MKCAVQNCGNKFKARQKHSKQLSFFSFPKNPDILKKWISFCRKSNKEKLRAPQKSVICNEHFKEEDIQGGLQFQMGLCSKRTLRPGAVPCINKNDVSAIERERSEKRNNKKLVAELLEEAAAREAAEASGAIVIAPDFIRNTGIVSVPDFVSATGNAFIPFTPTPSESDPLAEEQAELDVSTKSGQDDSNINQQKCRTCHELFAVDDNAKDLCDEQNAVMLYHIEVITGIWIQCKDGMSPFMCPSCVRNLRTAIEFRETCIQTELHLAGSTVDILPVVIKENDSEPWVAPDSQDGQELLQISEDIVKEEYVSVFPAEAQNGQTTVVEPLSVATAAQKTIEAINPPGADPESLALGAQIYEDLLNEYRGKDKTPRPRQRKVTINRTKSARQRKRKPREPKPKRPKRTKEERNRIRREQIRAMPLNHVCDQCGASFRVRCNLTIHMLRHTRTKNYPCSECPKKFYDAYMRNIHIRVRHRGELPFACNFCRKAFGSSNTRYLHEKKVHGATPRIHRNASRLNKRIELKEQQTELTLEEQEQKANLRHFCTYCDKSYATKYALNWHTNHHTGVTPFKCKLCDTTFADPQSKKKHEMQHDSKRPYECDICLKGFYVRSKLREHERIHTGERPYRCDVCNAFFRYKFNLYSHQFSKMHKENLRKPTKIEVSDESN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00506143;
90% Identity: iTF_00496126;
80% Identity: iTF_00588877;