Basic Information

Insect: Drosophila robusta
Gene Symbol: -
Assembly: GCA_004143805.1
Location: SCDV01000646.1:10805-16375[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0022 0.27 12.3 0.4 1 23 146 168 146 168 0.98

2 14 0.00011 0.014 16.4 1.3 1 23 390 412 390 412 0.98

3 14 4.6 5.8e+02 1.9 0.4 1 23 418 441 418 441 0.90

4 14 1.9 2.4e+02 3.1 0.4 1 23 464 487 464 487 0.93

5 14 0.00098 0.12 13.4 1.9 3 23 748 768 747 768 0.92

6 14 0.039 4.9 8.4 1.4 1 23 774 797 774 797 0.98

7 14 0.99 1.2e+02 4.0 1.8 2 23 834 855 833 856 0.87

8 14 0.0067 0.84 10.8 0.7 1 23 877 900 877 900 0.97

9 14 0.013 1.6 9.9 0.4 1 23 1121 1144 1121 1144 0.91

10 14 0.00055 0.069 14.2 4.4 1 23 1157 1179 1157 1179 0.98

11 14 7.6e-05 0.0096 16.9 0.1 2 23 1185 1207 1184 1207 0.95

12 14 0.00078 0.098 13.7 3.8 2 23 1214 1238 1213 1238 0.90

13 14 0.04 5 8.4 0.1 1 23 1243 1265 1243 1265 0.97

14 14 0.082 10 7.4 1.5 1 23 1271 1294 1271 1294 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0022	0.27	12.3	0.4	1	23	146	168	146	168	0.98
2	14	0.00011	0.014	16.4	1.3	1	23	390	412	390	412	0.98
3	14	4.6	5.8e+02	1.9	0.4	1	23	418	441	418	441	0.90
4	14	1.9	2.4e+02	3.1	0.4	1	23	464	487	464	487	0.93
5	14	0.00098	0.12	13.4	1.9	3	23	748	768	747	768	0.92
6	14	0.039	4.9	8.4	1.4	1	23	774	797	774	797	0.98
7	14	0.99	1.2e+02	4.0	1.8	2	23	834	855	833	856	0.87
8	14	0.0067	0.84	10.8	0.7	1	23	877	900	877	900	0.97
9	14	0.013	1.6	9.9	0.4	1	23	1121	1144	1121	1144	0.91
10	14	0.00055	0.069	14.2	4.4	1	23	1157	1179	1157	1179	0.98
11	14	7.6e-05	0.0096	16.9	0.1	2	23	1185	1207	1184	1207	0.95
12	14	0.00078	0.098	13.7	3.8	2	23	1214	1238	1213	1238	0.90
13	14	0.04	5	8.4	0.1	1	23	1243	1265	1243	1265	0.97
14	14	0.082	10	7.4	1.5	1	23	1271	1294	1271	1294	0.95

Sequence Information

Coding Sequence: ATGGCGCATAAGCGTGTGAAAACAGAGGACATGGCagtgaattataaatttgcgtGTCGCTGTTGTCTCAAATCCGAGGCGGAGTTCTTCAAGCTGGACTCGCTAATCGAGTGCGGGATTGGCGATAACGATGCGTCCGTAACGAAAATACCTATTATACGCTTGCTATTGTTCTGCATGCGCACCGAAAATCTGCCCGAACTGCCGCAATACATTTGCGTTGAGTGCAGTAAAAGTTTGCAAATTGCCTATTTGTTCATACAGAACGGCCTGCGCGCACATGAGATACTCTGTCGCAAGCTGTGCCCCGGGCAGCTGAAGTCCACAGCGCGCTCGAATGGCCAGCACATGTCGCTGACGCAAGAGGCAGCTGTGGGGGAGGACGCGACGCTGGGCAGGCACGGGGAGCTGAAGCCAACAAAAGCCGCTGTGCGACACGAATGCAAAGTATGCGGTGCTATTATCTACAATCGCTTGGAGCTCAAGCAGCACATACGCATGCACACGGAATCGTCGCGACATCAGTGCAAATTGTGCAATTTTGTCACGCTTAAGCATCGCCAGCTGCCGGAGCATTATCGCAAGGCGCACGGCCTCACAGCGGCCCAAATTGAGCACCAGCTCAAACTACGCAGATCCATGCAGGCGGcagcaagtgcaacaacaacagtagcaacagcTGAGGACGATGATCAGGTGAAGGTGTGCACGCTGGAGGATATGGAGCTGCTGATACCCACTGTGCTGACGCCGGAGGACTTTTCGCATCCACAATTGGATGCAGAACAATTGCGTGATATTGAGCAACAATTGGCAAACTCGCTGCCCGTCTCGCAGCCCAGTTCAACGTACGCTGCTGAACCAACGATAGCTGCTGGCGGTGGCGCCAATATGAGCATAGGCGCCGAATTTCTGGTCATGCCCGACGGCTCATTGCAGCAGGTGAACGATGGCGGTGTCGTATTTGAGTATATCGACGATAGCAAGAACGCCGCCAATGCGACAACCAATATGACGCTGCAGAGTCTGTTGGGCGATTCAAAGACAGATTTAGCATATGGCGCCATGGATATTGATCTGAGCCATATGGTCGTCGACAATGCGCTGCCGCAGATAACAGTTAAGCCAAAGTcacggccagcgccagcgtcaACGGGCGCCCTGAAACACAAATGTAAACTGTGCCCCAAAGCATTTCCTACGGTGGCACGCCTGAAATCTCATCAATTAACGCATAGTCaTTTGCCAAAGTTCTATTGCGATCAGTGTGCCTACTATTCGCTGCGCAGTGCCGATCTCATCCAGCATTATACAACGGAGCACAAGTCCTGCGTTAGCGAGAGTCGAGCGAATAACTTTGATAAGCTGCCCGGGGACAAAAGTCGCATATATTCCTGCGACATGTGCCTGTTTGAGGCACAAAGCAGCGGTCAGCTGCGTGTACACTATAGCAATAAGCATCAGATAGTGCCCAGTGAGGTGCAGCTGCGTCCCACCTGGACGAGTGAGACAAGGCGGACGGACGGCAATACGACGCTAGCCGACGGCAATAGCTCCGCACACCCAGATATACCGATGGGCATCAAATATCCGCCAATAATGTCTTCGGCAACAACGGATCCAACAACGGCGTCAACAACTGTCATGGAGCAGCCGggacaggcaacaacaacaagtgtgGTAACGCCAAGTGGAGAGATTAATGTTGTGGTTGATGCCACATCGTTGTTCTATCCAACGGCTGCTACGGACCAGATAACAACTACCGAAggatcaacaacaacaaattcaaacacATTCGGATTGTTCCCAGATCAATCGTTTAGCAACAGTATGgcgagcacaacaacaatgtcgcAGGAGCCAAACGGTGTGCCTTCAACAACATCCACATCGAATCCAAATACTAGCATCTTTGGTGACATGCAGGATTTTATTGATAACACCGATGTGGCTGCCATATGCACTATACCCGCCGATGATATGCCAGTGGTCGATGGCGATGATATTGTTAttgataacaataatataagcCTGGACTTTGATGCCGAAAATCTGTTTGAAGACTTTGAGGACGTTGAGGTGGGCGAAgaggatgacgatgacgaggacgatgCCGAAAATGAAGATGAGAATGATAACAACGATGCGGCGGCCGATCAAAATCTATTGTTGACCAGCGACGATGACGATGTGGATGACTTTGATGACGAACAGTCGAAGCATCTGCAGAAACCATATTGCATCTATTGTAACAAGAAGTTTACCAGCCAATACAAGTTTGAGAATCACATGTTTGTACATCGCGgTTTGGCGCCCTATCGCTGTGAACTGTGCACGAATCTGTATAATATGAAACGTCTGCTCATACGGCATTATAAGACGGTGCACAAGCGGATGCCCACTCGGGATATGGTGCAGGCCAAGGGCGATAAGGTATCCGTGGCGCGTACAACCATTGAAAAGATACAAGCTACGAATGACAAACCTCCAATGCTAATGTGCGCCAAGTGCCCCTTCGAATGCGAACTGGAGAGTGACATGCGCAAGCATCTGAATGCGCATCACGGCATCAACGATGGCGTATCTGTGCATGCCAACGAAGTGTTTATTATACGCAAACTGCCCTATGAGTGTCCACGGTGCATTCGTTCATTTGCGGCCAAACGGACATTGAGTCGCCATTTGCAACGTAGCCATTTGGTGGACACAATCATTGAGATGCAGGCGCCTCAATTGACAACTAGCTCAGCGGCCACCACAACCACATCGACGGCAACAACCACATTGCCGTTGAACGCCAGTGAtggcaataaaacaacaacaacaacaacacaactgGATTCCAGCTTGTTGACGCCGCAAGACGCTGACACTGTcgacggcgatggcgatggaAAATGCGAAGAGAACGCGCTAGACAACAAAACAGGATTAAAAACGGAAAATTcagatacatatatcaaaaccgaaacaacaacaaaagaaacaaatacagcagcaacaacagaaacagaaactgtCACAGCCACAGCTGAAACACCAGAACATGCAACAATAGCAAAGACAAAAGCCGCagaagcggcaacaacagcaataacaactgaAAATACActaacatcagcaacaacaacaaccgcaggCTCTACGCTCTTTCCAACGCCTACGCCATTTGACTTTGACCTTGACTTTATTGGCGATGATACAcacactgccacgcccattaagaacaacaacgacagaTTCAACATTGCATCGAATTCAAGTCATCTGCTTAATGGCAGCGATAAGCTACTGAGTGCAGCGTTGGAGCCATCGCCAGTTAAGGATTTACGAACACGCCTGCCTCGTACACCCATCTTTGTGTGCAAGCAATGCAATCAGACCTTCGATGAGCTCGGCAAGCTGTTGCAGCACGAACTGGAGCAACATTCCAGCGGCATTGTTTCGCCGCGCAGTAGTTATCAGCACCAGTGCACGATCTGCAAAACCACATACCGTACCGTAACGCTACTCAACTATCATATGAAACGGCATGCGCCAGTGAAAATTCCGTGTAGACAGTGCCCCAAGGAGTTTGAGGAGAGTTCGGATTTGGAACGGCACATACAGTCCGAGCATACCGCCAATATGCCACTGAAATGTGGCGTGGATGGCTGCACGAAGACATTTAACTATAAACATCATCTGAAGCGTCATCAGACAGCCTCCCATACGCCGGTTCAGTATATTTGTCCGGAGTGCGGACGCGATATGCTAACCAGTCTGCAGCTGAGGAATCACATGTCCATGCACAAGGGCACACATTCGTACAAGTGTCCGAAATGCGTGCGTACGTATTTGCGACGAAAACCtttccgAAGACATGCGCTACGTGAGCACAAGTGGGAGCTAACCGAGGAggaaattgataaaatatattgcgtAAATGATACATTGCCGTCAATTAAGTTGCGTGAACGAAGATCGGTGAAGGTTGAGCATGAGCAGTCTGACTAG
Protein Sequence: MAHKRVKTEDMAVNYKFACRCCLKSEAEFFKLDSLIECGIGDNDASVTKIPIIRLLLFCMRTENLPELPQYICVECSKSLQIAYLFIQNGLRAHEILCRKLCPGQLKSTARSNGQHMSLTQEAAVGEDATLGRHGELKPTKAAVRHECKVCGAIIYNRLELKQHIRMHTESSRHQCKLCNFVTLKHRQLPEHYRKAHGLTAAQIEHQLKLRRSMQAAASATTTVATAEDDDQVKVCTLEDMELLIPTVLTPEDFSHPQLDAEQLRDIEQQLANSLPVSQPSSTYAAEPTIAAGGGANMSIGAEFLVMPDGSLQQVNDGGVVFEYIDDSKNAANATTNMTLQSLLGDSKTDLAYGAMDIDLSHMVVDNALPQITVKPKSRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCAYYSLRSADLIQHYTTEHKSCVSESRANNFDKLPGDKSRIYSCDMCLFEAQSSGQLRVHYSNKHQIVPSEVQLRPTWTSETRRTDGNTTLADGNSSAHPDIPMGIKYPPIMSSATTDPTTASTTVMEQPGQATTTSVVTPSGEINVVVDATSLFYPTAATDQITTTEGSTTTNSNTFGLFPDQSFSNSMASTTTMSQEPNGVPSTTSTSNPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDDDDEDDAENEDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARTTIEKIQATNDKPPMLMCAKCPFECELESDMRKHLNAHHGINDGVSVHANEVFIIRKLPYECPRCIRSFAAKRTLSRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPLNASDGNKTTTTTTQLDSSLLTPQDADTVDGDGDGKCEENALDNKTGLKTENSDTYIKTETTTKETNTAATTETETVTATAETPEHATIAKTKAAEAATTAITTENTLTSATTTTAGSTLFPTPTPFDFDLDFIGDDTHTATPIKNNNDRFNIASNSSHLLNGSDKLLSAALEPSPVKDLRTRLPRTPIFVCKQCNQTFDELGKLLQHELEQHSSGIVSPRSSYQHQCTICKTTYRTVTLLNYHMKRHAPVKIPCRQCPKEFEESSDLERHIQSEHTANMPLKCGVDGCTKTFNYKHHLKRHQTASHTPVQYICPECGRDMLTSLQLRNHMSMHKGTHSYKCPKCVRTYLRRKPFRRHALREHKWELTEEEIDKIYCVNDTLPSIKLRERRSVKVEHEQSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598403;
90% Identity: -
80% Identity: -