Basic Information

Insect: Drosophila robusta
Gene Symbol: RREB1
Assembly: GCA_004143805.1
Location: SCDV01000477.1:106601-108594[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 2.5e-05 0.0031 18.5 0.3 1 23 435 457 435 457 0.99

2 6 0.0052 0.65 11.1 0.7 2 23 470 491 469 491 0.96

3 6 5.4e-06 0.00068 20.5 0.6 1 23 497 519 497 519 0.99

4 6 1.9e-06 0.00024 21.9 6.3 1 23 525 548 525 548 0.97

5 6 0.00099 0.12 13.4 5.2 1 23 555 577 555 577 0.94

6 6 1.5e-05 0.0019 19.2 0.3 1 23 582 605 582 605 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	2.5e-05	0.0031	18.5	0.3	1	23	435	457	435	457	0.99
2	6	0.0052	0.65	11.1	0.7	2	23	470	491	469	491	0.96
3	6	5.4e-06	0.00068	20.5	0.6	1	23	497	519	497	519	0.99
4	6	1.9e-06	0.00024	21.9	6.3	1	23	525	548	525	548	0.97
5	6	0.00099	0.12	13.4	5.2	1	23	555	577	555	577	0.94
6	6	1.5e-05	0.0019	19.2	0.3	1	23	582	605	582	605	0.95

Sequence Information

Coding Sequence: ATGTCGGCCACGGAGGAATTTTACCCAGATATAGAGGAGTGGTGTCGCCTCTGCCTGAAGGAACTCAAGGATGCACATCCAATATTCGACACAGACGACACGCAGCTGTCGATACAAATGCGCCTGATGGCGCTCCTCTCCCTGGAGGCGAAGCCAACCGACGGCTTGCCGAAGAAGATTTGCGGGGATTGTCGTTACCAGCTGGAGAAATCGTTTCTGTTCCGGCAGCGCAGCCAGGCGTCCGATAAAAAGCTACGGAAGCACATACGGCTCATCAACATGGGCAAGAAGAGCCGCGTTTTCGCCAAGCCATTGGACAACGATTCGGACGAGGACGAGCTGGAGTTCGAGGAGTCTAAGGCATTCATTGAGAAGCTGGAAACGCTGCAAAAGAAGAACGCCCAAAAATGGCGCGAAAAGTACACGCTGGATATGGAAAATGCGTACGAAAGGCGTATGGCGTCGGCGCAGGAGGTGCTGCGCATGCAGCTGACGGAGGAGGTGCGCGCCGATGTGCGGCGACAGCTCCGCGACGAGGTGCAGGAGGAGAGTCGTCGGGAGCAGCTTGCCAAGCTCTTGGGCGAACTAGAAGTGTTTCTGGCCGAAAAGAAAGCCGGGCTCTGGGAGACTTTGGCTGAGCTGCCGATGGATGCGAAGCCACTGAACGAAGCACAGCCGGAATCTGTGCCCGCAACGGTCGAAGTCACGAAGCCAGCAACGGAGCCGCGTTTGACACGCAAACGTGGTCGCGTCTCGTCGCCCACGGTTCAACAAAAGCGCCGGCCAAAGTCATCCGAATCGGAGTTTGTGCTGGAAAGCGAATCCAAAGTGGAGACGCTGTCCACAGACGACGCGGAACTGGACGCATCCGCGGCAGAGACGACGGACAGCTACCGTGACATAAAGATGGTCGGCGCTGGCGACGTGGTGACCAGTCAAAACGGCGAAATCTATATTATAAATGCGGCCGCTTCAAACGCGAACTCGACGCCCACATCCTCGACAGAGTTTCAGCCGGAGAAGAACATCACGTCTTACAACATCAGGGACAACGGCGAGATTCAGTTTAACGACGACAAGTCCGAGGATATTGGCGATGTGATGGTGTTCAATCTGGACGCGGAGGTCGGCGACGATCAGCAGCTGTACGAGTTCAACGAGAATGTCATTATACTGTCCAACGAGAAGGCAGCCAGCGAAATCTCAACCTCAGTGAAGAGCACAAAAGGCGACTTTGTGGTGAAGCGAGCGCCGCGCAGCTCGAAGCCCAACATTGGACGCGCCAGCGATACGATCAAGACGTTCCAGTGCCAGCTATGCCCGATTGCTTTTGCCACCGAGAAGACGCTCTCGCGGCACCTGAGCACCCACATCAAGACGCTGAAGAACGGCACCGGCGGCGCCCTCAAGTGCCCCgtttgccagctgcagctgtccTGCGCCAGTTCGCTGAAGCGCCACATGATCATCCACACGGGCCTCAAGCCGTATAAGTGTGACGCCTGCGATTTGTCGTTCTCGCAGCGCGAGGTGCTCAAGCGGCACATGGACACCCATACGGGCGCGAAGCGGCACCAGTGCCCCCACTGCGACACCTGCTTTGCCCAGAAGACCaatctgcagcagcacatcAACCGGATGCACATGGACGGCGAACGGCAGCACAAGTGCCATCTCTGCAAGCGCAGCTTCAACCACGTCTCGGGCCTGAGTCGCCACCTGGTGGCCCACGCGGGCGTCACGTTCGCCTGCAAGGAGTGCGGACGCCAGTTCAACGATCGCAGCGCTGTCCAGCGGCACGTCCAGAACGTGCACAAGGTCAAGGACACGGGCGCCGACTCGGCCACGGAGGGCAATGGACACGATACGGAATTCGACTAA
Protein Sequence: MSATEEFYPDIEEWCRLCLKELKDAHPIFDTDDTQLSIQMRLMALLSLEAKPTDGLPKKICGDCRYQLEKSFLFRQRSQASDKKLRKHIRLINMGKKSRVFAKPLDNDSDEDELEFEESKAFIEKLETLQKKNAQKWREKYTLDMENAYERRMASAQEVLRMQLTEEVRADVRRQLRDEVQEESRREQLAKLLGELEVFLAEKKAGLWETLAELPMDAKPLNEAQPESVPATVEVTKPATEPRLTRKRGRVSSPTVQQKRRPKSSESEFVLESESKVETLSTDDAELDASAAETTDSYRDIKMVGAGDVVTSQNGEIYIINAAASNANSTPTSSTEFQPEKNITSYNIRDNGEIQFNDDKSEDIGDVMVFNLDAEVGDDQQLYEFNENVIILSNEKAASEISTSVKSTKGDFVVKRAPRSSKPNIGRASDTIKTFQCQLCPIAFATEKTLSRHLSTHIKTLKNGTGGALKCPVCQLQLSCASSLKRHMIIHTGLKPYKCDACDLSFSQREVLKRHMDTHTGAKRHQCPHCDTCFAQKTNLQQHINRMHMDGERQHKCHLCKRSFNHVSGLSRHLVAHAGVTFACKECGRQFNDRSAVQRHVQNVHKVKDTGADSATEGNGHDTEFD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00526814;
90% Identity: iTF_00598390;
80% Identity: -