Drob021283.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila robusta
Gene Symbol
-
Assembly
GCA_004143805.1
Location
SCDV01002982.1:1664-4923[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0065 0.81 10.8 0.7 2 23 143 165 142 165 0.90
2 12 6.5e-06 0.00082 20.3 3.4 2 23 179 201 178 201 0.96
3 12 0.16 20 6.4 8.7 2 23 482 503 482 503 0.97
4 12 1e-06 0.00013 22.8 2.8 1 23 509 532 509 532 0.96
5 12 0.0003 0.038 15.0 0.4 1 23 537 560 537 560 0.96
6 12 0.00012 0.015 16.3 4.6 1 23 578 600 578 600 0.96
7 12 0.00011 0.014 16.4 1.2 1 23 605 627 605 627 0.98
8 12 2.7e-05 0.0034 18.3 1.7 1 23 633 655 633 655 0.95
9 12 1.9e-05 0.0024 18.8 0.7 1 23 661 683 661 683 0.98
10 12 2.8e-07 3.6e-05 24.6 2.7 3 23 691 711 690 711 0.99
11 12 6.3e-08 7.9e-06 26.6 1.7 1 23 717 739 717 739 0.99
12 12 1.3 1.6e+02 3.6 5.2 1 19 744 762 744 767 0.88

Sequence Information

Coding Sequence
ATGCCTGACAGCTGCGGCCAGATCGACGCGGAGCGCGTCTGTCGCGTTTGCCTACGCGAGGTGGGCGATTTCTACTTCATCTACGACGAGACGCCCGTGGAGCAGGGCGCAAACATTGCCCAGATACTTAACGAGTGCACGCGCTACGCCTGCGAGCGTTATGACAAGTTGCCGCATCACATGTGCGACACCTGCATCAAGGCCGCCTGCCAGGCGTATCGCTTCAAGCTGGACGCGGAGAAGGCCTATCGCTCGCTGGTGGCCATCTTGGGGCGTACGCCCGTCCCCAGGGCCAACAGTAGCGAGGTGTGCACCCAGACAGACCAGGTGCCGATGCTGCCGTGCGGCATCTGCAACGATCAATTTCTGAACATTCTTGAGCTACGACTGCACCGCAATCACCAGCACAAACACATGGAGCAGCTCAAGTGCAAGCTGTGCGACGAGCAGTTCCAGCAAATACGCCAGCTGCGCAACCATCTCGTGGAGCGGCACAATCAACAGGCGGCAGCGCCGTTGCTCCGCCGCCGCCTGGAGTGTCGCCTCTGTCAACGCTCCTTCACCCGGCGCGATCATATGCTGCGCCACATGCGCACCGAACACAATGCTGATGGCCGGGGGAGTCGGCTGGTCCGAACGCTGGCCGAGCAGCAGGTAGTTCAGTCTGACGCGGCCTGGCCGCCCGTCGACGAGACGACCATGCACAGTGGCGACGAACTGGAGTCGGCGGCCGTTCTATTCAACGAGGCGGCTGCCTGCTCCGACGATGATGGGAATGTTAACTACGAGAGTGGATATCAATGCCATACGAATCCCATATCAAGCAACGAGGAAGCTGACGACGAAGACGTGCATGCCGAGGCTAAGGAATCGCTCTGGCTGCACATTAAGCCAGAGCCGGaagcggatgcggatgcggatctGGAACACTGCCCGGCGCAAGTGCAGCGCGAGAAGCGCAGGAAAAAGGCAAACATAAAAACTTCCGCCCACACTGACACGGAGGACGAGCATGAGAGTGCAGACAAGCGGCAAACGACGTCCACTGCTTTGACAGTAGAGGTTAAAGaGGAGCCGCTGGCCACCGGCGGTGAGCAACAATTGTCCATAAAGCAGGAGCGGCAGCGCGTTGACAGCGTTAAAGAAGATGAGGACGAAATGGAGGCGATAACAGCTAACGTTGCGCATAGTgcggatgaggatgaggacgTGGATGCATTTGGCAATGAGGAGAGCGACATCGATCaggacgatgacgacgacgacgatgatgacaaCGAAGATGAAGACGAGCCGGACCCCGACCTCGAGGCATATGCCGAGGGCAAGTCCCAGGTGGCCCAGGTGGAAATTGTGCGCGAGTATCTGGAGAAGCCGACAGGTGGCaagcagcggcggcgtcgaCGCAAAAAACCGAACGATGCGGAGCCAAATCCGGAGAATCGCTGCGAAATCTGCATGCGCACCTTTTCCCGCCATTGCCATCTGCTGCGCCACAAACTGTCGCATTTGGAGAAGAAGCCGCACAGCTGCCCGCACTGCCCGAAGGCGTTTGCGCGCAGCGATCATTTGAAGGCGCACGTTCAGAGCCTGCACGGCAACAAGGAGCACAAGTGCGTGCTGTGCGATGCGGCGTTCGCCCGCCTCGATGCCCTCGAGCGGCACAAGATGAGCAAGCACAACGGCGAGGGCCTGGACGCCAGCAGCGAACTGAAGCTGCAAATGAGCGAGCACACGTGCGAATATTGCGCCAAGCGATTCTCCAGCAAGACGTACCTGCGCAAGCACACGCTGCTCCACACCGAATTCCTTTACGCGTGCAAGAGCTGCGACGAGACATTCAAAGAGCGCCAGGAGTTGCGCAGCCACGAGAAGACCCACACCGGCCAGCGGAACTTCCTCTGCTGCATTTGCGGCGACAGTTTTGCGCGCAACGATTATCTGCGCGTCCATATGCGGCGGCACAATGGCGAGAAGCCATACAAGTGCCGTTACTGCGTCAAGGCATTTCCACGCGCCACCGATCTTAAGGTACATGAGCGCTATCACACGGGCACCAAGCCGAATCTGTGCAACACGTGCGGCAAGAGCTTCCATCGCGCCTACAACCTGACCATACACATGCGCACCCACACCGGCGAGCGGCCCTACAAGTGCGACCAGTGCTCGAAGAGCTTCAGCCAGAGCAACGACCTCAAGGCGCACATACGCCGCCACACGGGCGAGCGGTACAAGTGTCCGCACTGCGATGCGTACTTCCTGCAGCTGTATCATATGCGCAACCATTGCCTCAGTGCCCACAACAAGCACATTGAGACGAAAACGGGCCGCCTGCAGCGGACCGGGCTGCTGGACGAGCCGAATCACTCGCATCTGACCACTGTGGTCATGCCGCCGGCCCGTTTTCAGCAGTCAGCGCCAGACGCCCAGCTGCCGGCAACGACGGCGCCGCCAATTGCAGCGCCAATTGTTCATTCGCCGGTTGCGTACAGCACCGCGTCGCCCGTGTCCGTGCCAGTGCCGGATCCGCCCGGATTTGCGGGTGCTGCGAGCAATgcaacagcgacggcgacggcaccCTTTGGTGCCTTCAATATAGCGCCCGTGGTGATGGcGCACCTCATGTACAACCAGGGCGGCAACAGCCAGCAGAGcaacgccagcggcagcgaggCGGGAAAATAG
Protein Sequence
MPDSCGQIDAERVCRVCLREVGDFYFIYDETPVEQGANIAQILNECTRYACERYDKLPHHMCDTCIKAACQAYRFKLDAEKAYRSLVAILGRTPVPRANSSEVCTQTDQVPMLPCGICNDQFLNILELRLHRNHQHKHMEQLKCKLCDEQFQQIRQLRNHLVERHNQQAAAPLLRRRLECRLCQRSFTRRDHMLRHMRTEHNADGRGSRLVRTLAEQQVVQSDAAWPPVDETTMHSGDELESAAVLFNEAAACSDDDGNVNYESGYQCHTNPISSNEEADDEDVHAEAKESLWLHIKPEPEADADADLEHCPAQVQREKRRKKANIKTSAHTDTEDEHESADKRQTTSTALTVEVKEEPLATGGEQQLSIKQERQRVDSVKEDEDEMEAITANVAHSADEDEDVDAFGNEESDIDQDDDDDDDDDNEDEDEPDPDLEAYAEGKSQVAQVEIVREYLEKPTGGKQRRRRRKKPNDAEPNPENRCEICMRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHGNKEHKCVLCDAAFARLDALERHKMSKHNGEGLDASSELKLQMSEHTCEYCAKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQELRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCSKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDEPNHSHLTTVVMPPARFQQSAPDAQLPATTAPPIAAPIVHSPVAYSTASPVSVPVPDPPGFAGAASNATATATAPFGAFNIAPVVMAHLMYNQGGNSQQSNASGSEAGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00547491;
90% Identity
iTF_00598300;
80% Identity
-