Drob011737.1
Basic Information
- Insect
- Drosophila robusta
- Gene Symbol
- -
- Assembly
- GCA_004143805.1
- Location
- SCDV01000754.1:25989-27440[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 5.1e-06 0.00064 20.6 0.7 2 23 12 33 12 33 0.95 2 11 1e-05 0.0013 19.7 3.6 1 23 39 62 39 62 0.96 3 11 3.3e-07 4.1e-05 24.4 1.2 1 23 146 168 146 168 0.99 4 11 0.00019 0.024 15.7 2.9 1 23 174 197 174 197 0.98 5 11 0.054 6.8 7.9 3.0 1 23 203 226 203 226 0.92 6 11 0.0057 0.72 11.0 1.8 1 20 231 250 231 252 0.86 7 11 0.0063 0.79 10.9 5.9 1 23 275 297 275 297 0.98 8 11 6.1e-06 0.00077 20.4 1.9 3 23 308 328 308 328 0.98 9 11 7.2e-06 0.0009 20.1 3.6 1 23 334 356 334 356 0.98 10 11 3.3e-06 0.00041 21.2 0.4 3 23 365 385 363 385 0.96 11 11 5.7e-06 0.00072 20.4 0.8 1 22 391 412 391 415 0.92
Sequence Information
- Coding Sequence
- atggcaaatgtcgcaaaagtgaaaagtttaAACAGCTGCGATACATGCGGCAAGTGCTTTGCCAAGCCAGCGCTACTGCGTCGCCATCTGGTCGTGCACAGCACGGAGAAACCCTTTGCCTGCGACCGCTGCTCGAGTTGTTTCTCGCAGAAGAGTTCGCTGCAGCGTCACATACGCATTAAACACGATGTGGCCCTAGAGCGGGATGACTCCGCGGTAGCGCAACATGCGCTGGCTGCCCTGAAACTCCTCCAGGCCAGTCACATAAGCCCCGATATAGAAGCCCCACTCGAGCGGCAAACTCGTGTGGAAGCCACACTTGAGGAGCAACCGGCTTGCGAGCTGGTGCTGCTAAAAGATAAACTGCAGCCAAATGGAGAGGTGCAAATGTTGTCGACGCAGCGCATAATTCGATTAAAGTGCAGTAGATGCTACTATGTGTGTGAATATTGTGCCAAGGAATTCAGCAAGAGCTACGATCTCATCAGGCATCGACGCACGCACACCAAAGAGACGCCCTATCCATGCAGCCGCTGCCTAAAACGTTTTGTCACCCAGGCCAAGTTGAACGAGCATCACAGGCGCCAGCATGCCACGTTAAAGAAGCACGCCTGCAGCGAGTGCAGCGCCAGCTACAGTGCCAAGAGACAGCTGCACCAGCACCTGACGCAGCGGCATCCCAATTTGATTCACAAATGCGCGCACTGCGGACGCACCTTCCCGACGAGAGCTGCGTGTGAGGCACACGAGAAACGCGAGGCGGATCCACAGCTGGACAAGCTCAGGCAATTGTTGCCGCAGCCCGTGTTAACGGAGCGCAGCTACAAGTGTGTCTACTGTGCGAAGCAGTTCAAACGAAAGTTCAATTGCCGTAGCCACATGCTATTGCATGTGCGGCGTTTAATGGACATGCGAAATGGCTGCCTGCAATGTGGCAAGCACTTTAAGCGACCCAATGATTTGGCGCGTCATCTGCTGACACACTCCAAGCTCAAGTTGCACACTTGTCGGCTATGCCAAAAAAGCTTTACGCTCAAGTCCACGCTGGCCAGGCACATGGACACGCATCAGGCGCAACGCAGCTCGGTTAATTGCCAGGTATGCGGCAAGTCGTATGCCTCCAAAACGTCTCTGCGTCTGCATCTACGTCTGCACACAGGTGAGCGACCGTTTCAGTGTGACATCTGTGGTGAAACGTTTCGCACGTCGGGGCACAGGCTGGAGCATATGCGCGCCGAGCGGCACAAAAGTGCTAATACATTCATCTTACACgattcaattatataa
- Protein Sequence
- MANVAKVKSLNSCDTCGKCFAKPALLRRHLVVHSTEKPFACDRCSSCFSQKSSLQRHIRIKHDVALERDDSAVAQHALAALKLLQASHISPDIEAPLERQTRVEATLEEQPACELVLLKDKLQPNGEVQMLSTQRIIRLKCSRCYYVCEYCAKEFSKSYDLIRHRRTHTKETPYPCSRCLKRFVTQAKLNEHHRRQHATLKKHACSECSASYSAKRQLHQHLTQRHPNLIHKCAHCGRTFPTRAACEAHEKREADPQLDKLRQLLPQPVLTERSYKCVYCAKQFKRKFNCRSHMLLHVRRLMDMRNGCLQCGKHFKRPNDLARHLLTHSKLKLHTCRLCQKSFTLKSTLARHMDTHQAQRSSVNCQVCGKSYASKTSLRLHLRLHTGERPFQCDICGETFRTSGHRLEHMRAERHKSANTFILHDSII
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00598299;
- 90% Identity
- iTF_00598299;
- 80% Identity
- -