Basic Information

Insect: Drosophila robusta
Gene Symbol: -
Assembly: GCA_004143805.1
Location: SCDV01000447.1:32868-34974[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 1.6e-06 0.00021 22.2 1.7 2 23 89 110 88 110 0.98

2 16 0.00089 0.11 13.6 4.8 1 23 116 138 116 138 0.96

3 16 0.0041 0.51 11.5 4.7 1 23 144 166 144 166 0.98

4 16 1.5 1.9e+02 3.4 1.8 1 12 172 183 172 185 0.87

5 16 0.00068 0.085 13.9 0.1 2 23 190 211 189 211 0.97

6 16 6.2e-06 0.00078 20.3 4.9 1 23 217 239 217 239 0.98

7 16 0.0021 0.26 12.4 3.8 1 20 245 264 245 267 0.94

8 16 0.0032 0.4 11.8 0.6 1 20 379 398 379 399 0.94

9 16 2.3e-07 2.9e-05 24.9 2.9 1 23 413 435 413 435 0.98

10 16 1.6e-07 2e-05 25.4 2.2 1 23 441 463 441 463 0.99

11 16 7.7e-06 0.00096 20.1 4.3 1 23 469 491 469 491 0.99

12 16 1.7e-07 2.2e-05 25.2 2.5 1 23 501 523 501 523 0.98

13 16 1.8e-06 0.00022 22.0 4.6 1 23 529 551 529 551 0.99

14 16 9e-08 1.1e-05 26.1 2.5 1 23 557 579 557 579 0.98

15 16 0.00015 0.019 16.0 4.6 2 23 586 607 585 607 0.97

16 16 0.00014 0.018 16.1 8.3 1 23 613 635 613 635 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	1.6e-06	0.00021	22.2	1.7	2	23	89	110	88	110	0.98
2	16	0.00089	0.11	13.6	4.8	1	23	116	138	116	138	0.96
3	16	0.0041	0.51	11.5	4.7	1	23	144	166	144	166	0.98
4	16	1.5	1.9e+02	3.4	1.8	1	12	172	183	172	185	0.87
5	16	0.00068	0.085	13.9	0.1	2	23	190	211	189	211	0.97
6	16	6.2e-06	0.00078	20.3	4.9	1	23	217	239	217	239	0.98
7	16	0.0021	0.26	12.4	3.8	1	20	245	264	245	267	0.94
8	16	0.0032	0.4	11.8	0.6	1	20	379	398	379	399	0.94
9	16	2.3e-07	2.9e-05	24.9	2.9	1	23	413	435	413	435	0.98
10	16	1.6e-07	2e-05	25.4	2.2	1	23	441	463	441	463	0.99
11	16	7.7e-06	0.00096	20.1	4.3	1	23	469	491	469	491	0.99
12	16	1.7e-07	2.2e-05	25.2	2.5	1	23	501	523	501	523	0.98
13	16	1.8e-06	0.00022	22.0	4.6	1	23	529	551	529	551	0.99
14	16	9e-08	1.1e-05	26.1	2.5	1	23	557	579	557	579	0.98
15	16	0.00015	0.019	16.0	4.6	2	23	586	607	585	607	0.97
16	16	0.00014	0.018	16.1	8.3	1	23	613	635	613	635	0.99

Sequence Information

Coding Sequence: ATGAGCACACTAATAGACGTGTCCTGCGTAAAAGtggagcgggagcaggaggAAGAGCCGGCGGTGATGGGTGCTGTGCTGAGGGACGCCAACTGCACCTATATCAAAACTGAAAGCAATTTAATGGAAATGGATATAGGACCCGTTAAAATAGATCCGCAAATGTCGGCGGAGCTCCACAGGCAGCCAACCGTAAGGAGTCGGCGAAAAAAGCCGAGCCCTGAAACCATCAACGACGCTCAGAAGGCTGCCAAAGGACTCAACCAGTGCCCCCACTGTCCTCGGCATTTCGAGAGACGCGACGAACTCGAGATACATATGCAGATACACACCGATAAGCTGCCCTACAAGTGCTCTCACTGTCCGATCAGTTTTTCacataaatcgatttttacgTCCCACATGTACGGGCACACGGGTAAATTTCCCCATCAATGCACCGAATGTTCGCAGGGCTTCCTTAAGTACTATGATCTCAAAAAGCATCGACGCACGCATACCCCTACTAATGTACACAAATGTCCGTTGTGTCCCAAGAAATGCATACACACGGGCAAAAGTCTGCTGCAGTGTCCGCAGTGTCCACGCGGATTTCTGAAGAGCTATGAGCTGAAAATTCATCTTCAGATTCACAGCGACAAACTGTCCTACAAGTGCCCACACTGTCCGAACAGCTTTGCGCACAAATCGAATTATATAGCGCACATGTGCGAGCACACGGGAGATTTTCCACACAAATGCCATCATTGTCCGCGTGGTTTCATGAAGAGAACTGAGCTGTTGAAGCACATATGGATTCACAGCGAGCAAGGTGCGGACAAATCCCGCGTCACAAAGATCTCGAAAGAGACCATAGATACAGCTTGTATCAAAAAGAAGCAGCTGGCGCCGGAGGAGCTAAGCAAACCTGTGTTGCGTTCATCACACGTTGAGGTCAAAGCTCAGGTCAACAAAAAACTCAAAGTGCCTGCGCAAGAAGTTGTAGCACCTGCCGGCATTAAAGTCGTGCCGGAGAGCAGCACAACGATAAGCTCTGCCAGGAAAAACAGTGCCTTAGATAAGTTAGACAGTAAAGATGTAATCAAAACAGGACCAGAGGAGCAGCCCTTGGTAAACGTGAGCTCAAGGCGAGTCCATCGGTGCAAGATCTGCAGCAGGGAGTTCGCAAACATAAAAGAACTGCGACTGCACGAGAAATGCTACACACACTCTAGCCGGCAGACGGGTAAACGGCCGTATAAATGCGATCATTGTGCGAAGACTTTTACACAGTCCTACAGTTTGACGGTGCACATGCGCGGGCATACGGGCGAACGGCCGTACAAATGTCCGCACTGCACGCGCACGTTTATACAGAATTCGGGTCTTAAGGTGCACATACGACAACATTCCGGCGAAAGGCCATATAAGTGCACCCATTGTCCGCGCACTTTTGCCAACTATTCGAATCGCAAGAAACACCTGCAGATCCATGGCGCTGACATGGCCAGCGGTCATCCGTACAAATGCCCGCATTGCCCCAAAACGTTTGCACAAAACTCGCACTTTATTGTCCATGTACGGGGACACACCGGCGAGCGTCCCTATCAATGCACCTATTGTACGAAAGGCTTTAAAGTGAGTCACGATCTGAAGAAGCATCTGCGCAGCCACACGGGCGAGCGTCCGTTCGAGTGTCCGCATTGTCCGAAAACCTTTGCTCAGAATTCGCATTTCAATGCACATCTCCGTGGACACACCAGCGAACGATCTCTCAAGTGCCCCCATTGTCCGCGCACCTTTTTAAAGAGCTACAATCTAAAGGTGCATTTGTGCACCCATACTGGAGAGCGGCCGTACAAGTGTCCGCATTGTCCCCAAACCTTTACTCAAAGCTCGCATTGCAAGGTGCACCAGCGCCAGCATTCGAAATGA
Protein Sequence: MSTLIDVSCVKVEREQEEEPAVMGAVLRDANCTYIKTESNLMEMDIGPVKIDPQMSAELHRQPTVRSRRKKPSPETINDAQKAAKGLNQCPHCPRHFERRDELEIHMQIHTDKLPYKCSHCPISFSHKSIFTSHMYGHTGKFPHQCTECSQGFLKYYDLKKHRRTHTPTNVHKCPLCPKKCIHTGKSLLQCPQCPRGFLKSYELKIHLQIHSDKLSYKCPHCPNSFAHKSNYIAHMCEHTGDFPHKCHHCPRGFMKRTELLKHIWIHSEQGADKSRVTKISKETIDTACIKKKQLAPEELSKPVLRSSHVEVKAQVNKKLKVPAQEVVAPAGIKVVPESSTTISSARKNSALDKLDSKDVIKTGPEEQPLVNVSSRRVHRCKICSREFANIKELRLHEKCYTHSSRQTGKRPYKCDHCAKTFTQSYSLTVHMRGHTGERPYKCPHCTRTFIQNSGLKVHIRQHSGERPYKCTHCPRTFANYSNRKKHLQIHGADMASGHPYKCPHCPKTFAQNSHFIVHVRGHTGERPYQCTYCTKGFKVSHDLKKHLRSHTGERPFECPHCPKTFAQNSHFNAHLRGHTSERSLKCPHCPRTFLKSYNLKVHLCTHTGERPYKCPHCPQTFTQSSHCKVHQRQHSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598286;
90% Identity: -
80% Identity: -