Basic Information

Insect: Drosophila rhopaloa
Gene Symbol: grau
Assembly: GCA_018152115.1
Location: JAECXI010000115.1:1216548-1218697[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 7.9e-07 5.7e-05 23.3 0.3 2 23 296 317 295 318 0.94

2 8 1.8e-06 0.00013 22.1 0.9 1 23 326 348 326 348 0.96

3 8 0.15 11 6.6 1.7 1 23 356 381 356 381 0.89

4 8 0.0011 0.079 13.4 0.9 3 23 388 408 387 408 0.97

5 8 0.057 4.1 8.0 0.2 2 23 417 440 416 440 0.86

6 8 8.2e-05 0.0059 16.9 2.0 1 23 447 470 447 470 0.96

7 8 6.5e-06 0.00047 20.4 0.8 1 23 475 497 475 497 0.97

8 8 6.4e-05 0.0047 17.2 3.8 1 23 503 526 503 526 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	7.9e-07	5.7e-05	23.3	0.3	2	23	296	317	295	318	0.94
2	8	1.8e-06	0.00013	22.1	0.9	1	23	326	348	326	348	0.96
3	8	0.15	11	6.6	1.7	1	23	356	381	356	381	0.89
4	8	0.0011	0.079	13.4	0.9	3	23	388	408	387	408	0.97
5	8	0.057	4.1	8.0	0.2	2	23	417	440	416	440	0.86
6	8	8.2e-05	0.0059	16.9	2.0	1	23	447	470	447	470	0.96
7	8	6.5e-06	0.00047	20.4	0.8	1	23	475	497	475	497	0.97
8	8	6.4e-05	0.0047	17.2	3.8	1	23	503	526	503	526	0.98

Sequence Information

Coding Sequence: ATGGATATCTGCCGCCTGTGTTTGCGCGGAGTGAGCGGCGCCCAGATGTGTCTACAGATCTTCGATGTGGACTCGGCGGAGAACAAGGTGGCGGAGGTGCTGCGCCAGCATTTCTGGTTTGAGGTTCTGCCCAACGACGAGATATCCAAGGTCATCTGCAACGTCTGCTGGACGCAGGTGTCCGAGTTCCACCAGTTCTACGTGTCCATACAGGAGGCGCAGGTGATCTACGCCACCACCTCGAAGTTCAAGCAGGATCCGGAGATGGTGAACACCTCCTGGCCGGAGGAGGTGCTCATGCCGGCCGACGTGCTGGCCGTGGACAACGATGTGAGCGCCCAGCTGAACGTTAATCCGCTGGACGAGCTGGATCTGAGTCAGCCGTTGTCCCCGGAAGACAGCAAGGTGGGAATCAAAACCGAGCGGCAGTCCCCCGAAATGGACTTCGCCTTTGAGGACACCAACAATGATCATGACGAGGACTACGAGGACGACGAGGATGAGGATACCGACGACTTGATTGTGACACGGAGTGGACGCAAGCGCAAACGGGAGGTGGCCAAGCCAGCCAAGACGAAAAGGGCGGGTGCCGTGGGCAGGAAGGGCAAGGACAAGGTCGTGGCCAAGCGGGGGCCACCCAAGAGGATATTCAAGATGGAGCGACTGCCACCGTTCTGCAAGGAAGACGAGGAACTGATCAAGCGCTACATAGTCATGGGCTGCGAGCTGTGCATATTCCTGGCCGAGGACTTTGACGGAATCCGCGAGCACTTCAAGGATAAGCATCCGGATGAGAGGCCTTACATCAAGTGCTGCGGCCGCAAGCTCAACAAGCGCTGTCTCATCCAGGAGCATGCCCGGCGGCACGAGAATCCCGAATACATCAAATGCAAGGATTGCGGCAAGGTGTTCGCCAATTCGAGTGTGCTGCGTGCCCACTGGCTGGTACATCATGTACCCGACGAGGACTGCGACTTCCAGTGCGAGGACTGCGGCAAGCGCTTCTCACGGCGCAATCTGCTCGAGCTGCACAAGGGCTCTCATGTGCCCGTGAACGAGCGCAAGTTCATCTGCCCCCAGTGCCCCAAACACAATGCTTTCGCCACAGAGTACCACATGCAAGTCCACATCAGCATGCAGCATCGCAAGGCGGCCAACATCTGCCATGTGTGCGGCAAGAAGATCAAGGACAAGGCCGTCTTCGAGAAGCACGTTCGCCTGCACTTCGAGGAGAGTGGGCCTCGCATCAAGTGTCCGCGTCCGGACTGCGAGAGCTGGCTGAAGGACGAGGACAATCTCAAGCAGCATTTGAGGCGCCACAACGACGAGGGCAAACTGTTCATTTGCTCGGAGTGTGGCAAGAGCTGCAAGAACTCCCGAGCGCTGATCGGTCACAAGCGCTATTCCCACTCGAATGTGATTTACACCTGCGAACAGTGTGGCAAAACCTTCAAGAAGGACATTAGCCTTAAGGAGCACATGGCACAGCACACTGGCGAGCCACTCTACAAGTGTCCATTCTGTCCCCGCACCTTCAACTCAAACGCCAACATGCACTCTCACAAGAAGAAAATGCATCCAGTGGAGTGGGACATCTGGCGGAAGACGAAGACGGGTAGCTCCCAAAAAGTCCTGCCCAGCGCCCAAGTGGCTCAGATGTTCAGGGAAGATGCCGATGCCGCAGCTATTGCCAATGACTATTCAGCTTAG
Protein Sequence: MDICRLCLRGVSGAQMCLQIFDVDSAENKVAEVLRQHFWFEVLPNDEISKVICNVCWTQVSEFHQFYVSIQEAQVIYATTSKFKQDPEMVNTSWPEEVLMPADVLAVDNDVSAQLNVNPLDELDLSQPLSPEDSKVGIKTERQSPEMDFAFEDTNNDHDEDYEDDEDEDTDDLIVTRSGRKRKREVAKPAKTKRAGAVGRKGKDKVVAKRGPPKRIFKMERLPPFCKEDEELIKRYIVMGCELCIFLAEDFDGIREHFKDKHPDERPYIKCCGRKLNKRCLIQEHARRHENPEYIKCKDCGKVFANSSVLRAHWLVHHVPDEDCDFQCEDCGKRFSRRNLLELHKGSHVPVNERKFICPQCPKHNAFATEYHMQVHISMQHRKAANICHVCGKKIKDKAVFEKHVRLHFEESGPRIKCPRPDCESWLKDEDNLKQHLRRHNDEGKLFICSECGKSCKNSRALIGHKRYSHSNVIYTCEQCGKTFKKDISLKEHMAQHTGEPLYKCPFCPRTFNSNANMHSHKKKMHPVEWDIWRKTKTGSSQKVLPSAQVAQMFREDADAAAIANDYSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00494594;
90% Identity: iTF_00531851;
80% Identity: iTF_00494594;