Basic Information

Insect: Drosophila rhopaloa
Gene Symbol: Clamp
Assembly: GCA_018152115.1
Location: JAECXI010000036.1:1253685-1257042[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0016 0.12 12.9 1.1 1 23 127 149 127 149 0.99

2 7 0.00017 0.012 15.9 0.7 1 23 364 386 364 386 0.97

3 7 4.4e-06 0.00032 20.9 0.1 1 23 392 414 392 414 0.99

4 7 2.5e-06 0.00018 21.7 3.2 1 23 420 442 420 442 0.99

5 7 2.7e-06 0.0002 21.6 0.3 1 23 448 470 448 470 0.98

6 7 1.2e-06 8.7e-05 22.7 0.4 1 23 476 498 476 498 0.98

7 7 5.2e-05 0.0037 17.6 0.1 1 23 504 526 504 526 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0016	0.12	12.9	1.1	1	23	127	149	127	149	0.99
2	7	0.00017	0.012	15.9	0.7	1	23	364	386	364	386	0.97
3	7	4.4e-06	0.00032	20.9	0.1	1	23	392	414	392	414	0.99
4	7	2.5e-06	0.00018	21.7	3.2	1	23	420	442	420	442	0.99
5	7	2.7e-06	0.0002	21.6	0.3	1	23	448	470	448	470	0.98
6	7	1.2e-06	8.7e-05	22.7	0.4	1	23	476	498	476	498	0.98
7	7	5.2e-05	0.0037	17.6	0.1	1	23	504	526	504	526	0.97

Sequence Information

Coding Sequence: ATGGAAGACCTCACCAAAAACATTATCTTCACAAATGCTATTAATGGGCAACCTGCCACAATTCAGTACCAGACGGCAGATGGCACCATCCTTAAACAGCCTAAAATTGAGGGTCAAAAGGCGGAGCAGCAACCGACCTTCTACTACACGACAAATGGTAATGGCGGCACCGTCAATCTTGCCCAGTTGGCCACCACAGATGACAACAAGACGTGCTACATAGCTCAGCCAGTGGGCGGCTACAACTACGCCCTGGTAAATGGGATGCCGCTCAACCAGGGCGCAGCGCTTGGCATCGCCACTGTAGACGCTCAAGGCCGCATCCAGATCGTCAATCAGAACAAGCCTATTGCAGCAAACACCATATCCAACATCAGCTTCAAATGTGATGTTTGCTCGGATATGTTCCCCCACCTAGCGCTGCTCAACTCCCACAAGCGTATGCATACAGATGGGGAGCAACAGCAGCAACATCAGCACAACACCCAGCAGGGGGCCAGCGATTCAATAGCCGTCGTCAGCGCCCAGGGCTTGGTGCAAGCGCAGAACATCATTGGCAATGGCCAGATGGGGCAGATACAGATAGTGTCGTCGGACGCTTTGGAGCCGGTGCAACAATCTGTAATGCAACAGCACGACTCCAAAGCAAATAAGTGCATTAATTGCGGTAGCCCCATACTGCAGCAGTCCAAACGCAAAGGTCCAAAGCAGGTGCGTTGTGAGTCCTGCATGCAGGCAGAACAGACGGCGCAGCAACAACAGCAGCTTTTCGTGGCGCAGGAAGGTCAAATGGCACATCCCGTCCAGATCATATCAACCACCCCTCAGGCCCAGGCACAACTGCAGCAAATTGTAGCCGCGCAGACAGGCGACACGACTCCCAAGCGGGAGACCAGCAGTGGGCCTGTCCATCACCCAGTGAAAAAACGAAATTCCCAGCAGATGACCAAGTGCCAGAAGTGCAATGGCTCTGGAGTGGTGCTGGTAGGGCAGCACTCTCACGCCGGACAAAGTGGTGGGGGCGGAACGGTAAAGCAATCGGTCACTGTCAAAACGGAGTGTTCGTCCTGCAGGAATCCGTCGAAACCCTTTAGTTGCAATATATGTGGTGGCCTTTTCTCACGTTACTCAAGTCTGTGGTCACACAAAAAGCTCCACAGCGGCGAAAAAAACTACAAGTGCAGCATCTGTGGACTGGCCTTCGCCAAGGCCGTTTATTTAAAAAATCACGCGCGCATCCACACGGGCGAAAAGCCTTATAAATGTCAAACCTGCGGTATGCAGTTCTCACAGTCGCCACACTTAAAGAACCACGAACGCACGCACAGCGGCGAACGTCCCTACGTGTGCGGGGTGTGCGACAAAGGATTTGCTCGCCACGCTACACTTTGGAATCATAGGCGCATCCACACGGGCGAGAAGCCGTACAAGTGTGAAATTTGCGGGTCTGCCTTCTCTCAGGCGGCCCACCTAAAGAACCATGCCAAGGTCCACTCAGGGGAGAAGCCCTACAAGTGCGAGATCTGTTCTGCGGCGTTTGCTGATCGATTCGCGCTTAAACGCCACCGCGGTATACACCAAAAGTACGGACAAACGGCGCCTCGTCAGACCAGTAGTGATGGAATAATTGTGCACAAGCAAGAGATCCCCGACATGGATGACGAAGCCCAACAGGAGGTGATCATCGGTGGGTTATAG
Protein Sequence: MEDLTKNIIFTNAINGQPATIQYQTADGTILKQPKIEGQKAEQQPTFYYTTNGNGGTVNLAQLATTDDNKTCYIAQPVGGYNYALVNGMPLNQGAALGIATVDAQGRIQIVNQNKPIAANTISNISFKCDVCSDMFPHLALLNSHKRMHTDGEQQQQHQHNTQQGASDSIAVVSAQGLVQAQNIIGNGQMGQIQIVSSDALEPVQQSVMQQHDSKANKCINCGSPILQQSKRKGPKQVRCESCMQAEQTAQQQQQLFVAQEGQMAHPVQIISTTPQAQAQLQQIVAAQTGDTTPKRETSSGPVHHPVKKRNSQQMTKCQKCNGSGVVLVGQHSHAGQSGGGGTVKQSVTVKTECSSCRNPSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCSICGLAFAKAVYLKNHARIHTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYKCEICGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHRGIHQKYGQTAPRQTSSDGIIVHKQEIPDMDDEAQQEVIIGGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537677;
90% Identity: iTF_00524568;
80% Identity: -