Basic Information

Insect: Drosophila rhopaloa
Gene Symbol: ham
Assembly: GCA_018152115.1
Location: JAECXI010000002.1:11282298-11304037[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.013 0.94 10.0 0.0 2 22 330 350 329 352 0.88

2 9 0.046 3.4 8.3 3.3 1 23 359 382 359 382 0.90

3 9 3.1e-05 0.0023 18.2 0.2 1 23 388 411 388 411 0.96

4 9 9e-07 6.5e-05 23.1 1.6 1 23 417 439 417 439 0.97

5 9 2.1e-05 0.0015 18.8 5.5 1 23 445 467 445 467 0.98

6 9 0.00039 0.028 14.8 2.0 2 21 475 494 474 495 0.94

7 9 3.4e-08 2.5e-06 27.6 1.7 1 23 923 945 923 945 0.99

8 9 2.2e-06 0.00016 21.9 0.4 1 23 951 974 951 974 0.97

9 9 2.2e-06 0.00016 21.9 1.2 1 23 980 1002 980 1002 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.013	0.94	10.0	0.0	2	22	330	350	329	352	0.88
2	9	0.046	3.4	8.3	3.3	1	23	359	382	359	382	0.90
3	9	3.1e-05	0.0023	18.2	0.2	1	23	388	411	388	411	0.96
4	9	9e-07	6.5e-05	23.1	1.6	1	23	417	439	417	439	0.97
5	9	2.1e-05	0.0015	18.8	5.5	1	23	445	467	445	467	0.98
6	9	0.00039	0.028	14.8	2.0	2	21	475	494	474	495	0.94
7	9	3.4e-08	2.5e-06	27.6	1.7	1	23	923	945	923	945	0.99
8	9	2.2e-06	0.00016	21.9	0.4	1	23	951	974	951	974	0.97
9	9	2.2e-06	0.00016	21.9	1.2	1	23	980	1002	980	1002	0.98

Sequence Information

Coding Sequence: ATGCTGTTCGATCGTTTTGTCATATCAGGCTCCAGCGGCGAAGACTTCGATCCAAGTGCGAGTGTTGCGCGCCACCATCATCACCACCATCACCTGGATCTGAGTGCCAGGAGTCAGGGCTTCAATCCGCAGCCTGAGCAGATTGAGGACTTATTCGCCACCCGCCATCGCTTGCCGCCGCAGGATCCCGTGGACGGATCTCCGACGAGGCGGATTCAGGATCCGGAGCTCCTCCATCACCCCAATCATCTCCAGCAGCAACAGCAAAAGCAGCAGCAGCCACCGCCTCCCACGTTGCCACTGTCCGTGGAATCCCAATCCCCCGCCGCCGACGGCATGGAGTCCTTCTTCAAGGACCGCGCCCAGGCGGAGCACATCCTGCACGAGTGGGTGAGGAGACGCGATTCCGTCTGTGATCTGGACATCCGTGATAGCGGCGGCGTCTTTGCGAAGACGCCGCTCCAGAGGGGCACCCGCTACGGACCCTTCCCCATGAAGCTTAGCCACCAGCCCGACGATCAGCAGCTGGCATGGAAGGCATATAATGAATATTTTAATGGATGGCTGGAGCCCACATCCGATGTGTCCACGTGGTTGAAAAAGATCCGAACTGTTCAGGACGAGGGCATTGGCGAGGCTAATTTAGAAAGTTACATTAATGGCGGTTATCTGTGGTACGAAACGAATCGTTATGTGAATGCTGGCAGTGAAATGGTCGTCGACGGGCGGCCCAAGAGTCCTGTTCATCTGAACGAGAATTTCATGAACGGCGGAGGAGTCCTGGCAGCCGCAGCCGCCGCAGCAGCCGCTGCCGCCGCAGTGGCCGCCGCCTCGACCTCGGGACCGAAAAGCGGGGGCGGGGGCAGCTCCCTGCCCAGCGATGATCGCAGCGATCGTGATAATAGTTCTTTGTACAGTGGTGACGAATTCTCCAAAGATAAGAAAGGAGATATAGATTACGCAGACGACCAAACCAAATTCGATATTCGCTGCGAGGTCTGCGATAAAGTCTATCCGGATTTAGAACTTTTGGACGATCATCTGGTGGGTGCTCATCATTACAAGCAGGACGAATTCTCCTGCAAGAAATGCCCATTGCAGTTCTGCCATCGACTTTTGCTCATCAAACACGAAGGGATCTCACACAATAGTGAACGAAGATTTTCCTGCGAGAATTGCACCCTGGTATACCGTGACCCCTCGTTATTACAGCAACATATTCGCGCCAACCACGTCGGAGCTCGCTGTCATCCGTGTCCGGAGTGCGGGAAAACGTTCGGAACCTCGTCTGGGTTGAAGCAGCACCAGCACATCCACAGTTCCGTGAAGCCCTTCCCCTGCGAGGTGTGCCACAAGGCGTATACGCAATTCTCGAACCTGTGTCGGCACAAGCGGATGCACGCCACCTGCCGGAATCAGATCAAGTGCGACAAGTGCAACCAGAGCTTCAGCACAACGACCTCCCTAACTAAGCACAAAAAGTTCTGCGACTCGACGGGTCCGGTGTTTCGGAACCAGCACATCAATCGCCACCACCCGCATCAGCATCCACATCCGCATCCGCATCAGCATCAGCTTGCTCAGGAAATTCAGCAACATCTGACGGCGACTGTTACATCCACCTGTGCAACGCCAGCAAAGGAATCTTCGGAATCCTCGCCCTCAGCTGCTGTTGCCGCCGCCGCCGCCATGTCCTCGCCACCGAATCCCTTCATGATGTTTCGCCATGCACCGCCGTTCTTTCCCGGATTTCCGGCATACGGATTTCCCAACTTCCTACCACAAAATGCGCTGCATAATCCGAACTTTCCCATGTTCTTCTCAAAAACACCCATGGACATGGGCTGTGTCGCACCCGAGATTACTTCTCCGAATTCCGCCTTTGATCAGAAATTACCATTTGGCTTTCTGAAAAATAATTCCCCTGCTCTGGAGCCTTTAAACAAAGAAACGGATGAAGAGTTGGTCTACAAATCAGCGAAGAAGCTTAAGAGGGAGCCATTCCTGCATGTTTCCGAAGGCGAAGACGACGATAGCCGCAATTCCTTTGGCATTAAATTAAAGCCGGATGAGGTCAAAAATGGGATCAAGTCGGAGGAGCAGAAGGAGATAATGCGAGATGCCGAAAGAGGAAGTAGTCCCGATCAACAGCAGGTCGAAGATGATAGGAAATCCATCGACATCGTGAGCACTCCACCACCATCAGATACACCGTCTGCAGCCGATGCACCGCTGGACCTTTCCATATGTCGCAAGCGCTTAGGCTCATCCATCTCCTTTCTTCACGCTCCTTTACCGGAGAACGACCTGTTCGATAACTTTCTACCCAGAGTGCTAGAGTTCGAGAACGAAGGGGGGCCGCCCGTGCCGAAAGTGCGCAAATCGCACAGTTCGGCGGATTCCTCGAACTCGCACAAGTCCACGCCCACCGCCTCGCCGGAGCTCACCCCCTCGCCGTCGCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCACTTAAGCGAGTTACAGAGAAAGAGCCGCGTGCCCCCCACAATACTGGAGGACTTCTATTTAGCTCAGTTTCCTTTTTTATGGCAAACGGGCGGAGGGCCCGCCACTAAGCGGCCGCCTCCGCCCGGGAAAATCCCAACGGCCAAGGATCGCTACTCCTGCACGTACTGCAGAAAGGTGTTCCCCAGATCGGCCAACCTGACTAGGCATCTGAGGACGCACACCGGCGAGCAGCCGTATCCCTGCACTTTCTGCGATCGGGCATTTAGCATATCCTCGAACCTGCAGCGCCACGTAAGGAATATCCACAAAAAGGAGCGTCCCTTTCGCTGCGATATCTGCGATAGAACGTTTGGCCAGCAGACGAATCTCGATAGACATGTGAAGAAGCACGAGTTGGAGGGCAACAATTTCAGGGATTCGCCCAGTTCCGCTGGCAATGCCGAGTACTTCGATGAGATACGCAACTTTATGAACCGCGTCTGCACACCCAACAGTTTGGGTGGGAAGGAGAGCGATACCGAGGAGTATCCCAATAGCGAAGATCAGTCCTTGAACCTCGAAAAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCTCTTAA
Protein Sequence: MLFDRFVISGSSGEDFDPSASVARHHHHHHHLDLSARSQGFNPQPEQIEDLFATRHRLPPQDPVDGSPTRRIQDPELLHHPNHLQQQQQKQQQPPPPTLPLSVESQSPAADGMESFFKDRAQAEHILHEWVRRRDSVCDLDIRDSGGVFAKTPLQRGTRYGPFPMKLSHQPDDQQLAWKAYNEYFNGWLEPTSDVSTWLKKIRTVQDEGIGEANLESYINGGYLWYETNRYVNAGSEMVVDGRPKSPVHLNENFMNGGGVLAAAAAAAAAAAAVAAASTSGPKSGGGGSSLPSDDRSDRDNSSLYSGDEFSKDKKGDIDYADDQTKFDIRCEVCDKVYPDLELLDDHLVGAHHYKQDEFSCKKCPLQFCHRLLLIKHEGISHNSERRFSCENCTLVYRDPSLLQQHIRANHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFPCEVCHKAYTQFSNLCRHKRMHATCRNQIKCDKCNQSFSTTTSLTKHKKFCDSTGPVFRNQHINRHHPHQHPHPHPHQHQLAQEIQQHLTATVTSTCATPAKESSESSPSAAVAAAAAMSSPPNPFMMFRHAPPFFPGFPAYGFPNFLPQNALHNPNFPMFFSKTPMDMGCVAPEITSPNSAFDQKLPFGFLKNNSPALEPLNKETDEELVYKSAKKLKREPFLHVSEGEDDDSRNSFGIKLKPDEVKNGIKSEEQKEIMRDAERGSSPDQQQVEDDRKSIDIVSTPPPSDTPSAADAPLDLSICRKRLGSSISFLHAPLPENDLFDNFLPRVLEFENEGGPPVPKVRKSHSSADSSNSHKSTPTASPELTPSPSPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHLSELQRKSRVPPTILEDFYLAQFPFLWQTGGGPATKRPPPPGKIPTAKDRYSCTYCRKVFPRSANLTRHLRTHTGEQPYPCTFCDRAFSISSNLQRHVRNIHKKERPFRCDICDRTFGQQTNLDRHVKKHELEGNNFRDSPSSAGNAEYFDEIRNFMNRVCTPNSLGGKESDTEEYPNSEDQSLNLEKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00529731;
90% Identity: iTF_00494552;
80% Identity: -