Basic Information

Insect: Drosophila repletoides
Gene Symbol: -
Assembly: GCA_018150835.1
Location: JAECWQ010000202.1:6053236-6057390[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00039 0.027 14.9 0.1 1 23 146 169 146 169 0.96

2 14 0.0016 0.11 13.0 3.1 2 23 218 240 214 240 0.89

3 14 0.0041 0.28 11.7 0.2 1 23 345 368 345 368 0.93

4 14 0.48 33 5.1 5.9 2 23 417 439 416 440 0.95

5 14 0.0031 0.21 12.0 0.5 1 23 506 529 506 529 0.88

6 14 6.5 4.5e+02 1.6 0.1 2 14 548 560 547 572 0.83

7 14 0.00066 0.046 14.2 3.3 2 23 580 602 580 602 0.96

8 14 0.0032 0.22 12.0 0.1 1 23 697 720 697 720 0.95

9 14 8.2e-05 0.0056 17.0 0.2 1 23 771 794 771 794 0.94

10 14 0.0011 0.076 13.4 2.2 2 23 844 866 843 866 0.97

11 14 0.0012 0.082 13.4 1.4 1 23 945 968 945 968 0.92

12 14 0.11 7.6 7.2 2.8 1 21 1020 1040 1020 1041 0.95

13 14 0.5 34 5.1 0.4 2 23 1083 1106 1082 1107 0.70

14 14 2.1 1.4e+02 3.1 1.1 1 23 1125 1149 1125 1149 0.77

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00039	0.027	14.9	0.1	1	23	146	169	146	169	0.96
2	14	0.0016	0.11	13.0	3.1	2	23	218	240	214	240	0.89
3	14	0.0041	0.28	11.7	0.2	1	23	345	368	345	368	0.93
4	14	0.48	33	5.1	5.9	2	23	417	439	416	440	0.95
5	14	0.0031	0.21	12.0	0.5	1	23	506	529	506	529	0.88
6	14	6.5	4.5e+02	1.6	0.1	2	14	548	560	547	572	0.83
7	14	0.00066	0.046	14.2	3.3	2	23	580	602	580	602	0.96
8	14	0.0032	0.22	12.0	0.1	1	23	697	720	697	720	0.95
9	14	8.2e-05	0.0056	17.0	0.2	1	23	771	794	771	794	0.94
10	14	0.0011	0.076	13.4	2.2	2	23	844	866	843	866	0.97
11	14	0.0012	0.082	13.4	1.4	1	23	945	968	945	968	0.92
12	14	0.11	7.6	7.2	2.8	1	21	1020	1040	1020	1041	0.95
13	14	0.5	34	5.1	0.4	2	23	1083	1106	1082	1107	0.70
14	14	2.1	1.4e+02	3.1	1.1	1	23	1125	1149	1125	1149	0.77

Sequence Information

Coding Sequence: ATGGAAGGCATGGATCTGTGGACGTCGATGTTTTCGTCAGACTATGAGGAGGGGGAGGTGGATGATAGAACGAGAGAGAATAATGCTTATGGAGACGAGTTTATGGGCGATGAGGAAGAAGATCAGGAAGCGGATATAGACGAAGCGACGGAAGAGAAAGGACCAGATGATGATGCCATATTTGATTTTGAACTGGAACCAATTGTTAACATTTCTGAAGCGGTACCGGAACGTGCAAAAAGAGCAGTTCACTTGGCGCCACCGATGCCAGTTGGCGCAGCTGTGCGTCCAATGCATCGCCAGGCCTTGCATGCACCCTTTGGCAGGGGAGCAGCAGCAGCTGTTGGATTAGCTCCTGCCATGCGTCCCACAACCTCACAAATTAATGCAACCGATGAGAATGGTATGCCCATTAATTATGAACTGGGCGTCATATATATATGTCCAGCGTGTGGGGCAGAGTATCGTCAGCAGGACATGTGGAAGCGCCATATGAATCAGATGCATCAGTTTAATACTAGAAAAGGACTCAATTTTGTGGCCATTGATAAGCTCTATCAACGGTGTCTGGAGTGCAATAAACGCATTGCTATGCACAGCCGGGAGAATCTATTAAAGCACAAGTTTACGCATTTGCCATATCGCTGCACCAAGTGCTTCATCTGCAAGCGAGAGTATAAATACAGACAGGATCTGATGGTACATCTACGCATGGTTCATTGTGATGAGGTAATTGCCATGATGCGTGATAGCGATGGTACAGCTGGACGCAAGACGCGTGTGCGTGAACCACGCACTGAACCCCTTCATAAGGCTGCTCCTTATCCTGTGCCGGTTGAAGAAGCTGAAATAAATAACGAGCGACCGGCTGCAAGTGCTGCCGAAGAGTCCTTTCTTGGTGTGGATGAACCTAATCACAGTTCAAATCACGGCAAACGCAAGCGTATGAATATACTTGGGAATGGAAATGATGGGAATGGTGGAACTACTTCTGGATCTGGCTCGGCTGACATTTGCGAGGATTATATACACTACATGTGCCCTGACTGTGGCACAGATTGTGATACCCTCGCACAGTGGAACCAGCATATTGAATTCGTTCACGATTATGTCAGCCGGCGTGGCCTCAATTTTCGCTGTGTCGATATGCAGATGCAGTGCCTCGAATGCAAGCAGTTCGTCATCCCGAACACAATCAAGACTCTGCGTACGCACAAGTTCAGCCATTTGCCACAGCCAGATTGGATGCGCTGCAAGTTGTGCTATAAGGGTTACACGGAACATCATGAATTGGTTACGCATCTGCTTAAGCGACATCATTTGGAGACTTTGGTGCCAGAATCAATAGATGAAGAGCCAACAGCCAGTGGCAACGCCAGTATCAATGTCATAGATGATGTCGAGGATAATACAGACAATGGGCAATTCGATGATGAATCTTCGTCTCAATGGGACGATGCGCCACGTCGTGGTGGACGCATTGGTAACGATGATATGTATGAGCCGCACATAGACTATCTGTGCCCGCAGTGCGGTAGAGAGTTTATCGAGAAGAAACACTGGCGCACTCATGTGGTTCAGGTGCATGGCATGAATGATTTGGACAAACTCAACTTTGAGGTGATCAGTGATCGGCAGTTGAAATGTACGGAATGCGAAAAGATTATCACGAATGCTTATGGGATACAGAATGCTCAGCAACACAGGATTACGCATTTGCCATTTAAGGCTTATGCGAGATGTCGCAAGTGCCACAAGTCTTATACAGATCGCAAGGGTTTGGTCAAGCATTTGGCCACATATCATCGTGTGGGTTACGAGCCGCGTAAATCTAGCGGTGCTGGCGGCTTAAGTGGATCAAAGTTGCAGCCGCAGCGAAAACAAATTGTCACAGTGGCCAATGAAACATATGAGATTATCTACCTGGATGAGGAGCAATCCCCGCCAAATAATAATAATATCAATGAGGAGAATGATTTTGGGGAACAAATGCAAGATGACGATGATTTTTCCTGTCAATTGGTACCTCCGCCGCCAGCTGCTGCTGCGGTTACTTCGAATTCTAAGGCCAATCCGAATCCGAACCGCTATAAATGCGTTGATTGCGGAAGCTTGTTTCCCACACAGATGGCGCTCAAAGAGCACATTAGCGAGGAACACGATTTTACGGACACACAATATGGTGCCAAAACTTTTGATAATGCTGAGGCAACGGATGACGCATCTCCTGATCTAAGTTCTGTCCCAAGCAGTAGCAAAAGATCGGAAATAAATATAGCTGGGGTCTCCACGATCGAGCAAAATTATATATATTTATGCCCCTCTTGCGGCAAACCATACAAAACACAGTTTGAATGGCGGCGTCACATTAATGAAGCTCACAATTTTGATAAGCGTCAATATTTGAATATGCGTCAGTTGGACAAGTATCGCTATCAGTGCACACAATGCAAGGATATTGTATGCAATTCGAAGCTCAAAGGACTTCAGGATCATCATTTTCGCCATCTTCCATACCGATTGTATTTAAAGTGTTTGGTTTGTGGCACCTGCTATAATCACAAACCCAATATTGCAGCCCATTTGAGAACACGCCACAACATCTATGAAAGGGAGACGTCTTGGCGTGAGGTGCTGCCCAAGCAAGGCAAAGATAAAGACATGTCGTCCGGCTCATCATCTCCCACACATTTGGCCATCAGTGGTAGCAGCAGCTTGGTGGGACGTTCGCTCAAACCACAGCCTGGCGTGTTGCCAATACGACCCGCAGGCCTGAATACTCTAGAGGACAGTATTTCGTATCATAATGCTGTGGATCTGGACTTTATTACGTATTACTGCCCCAAGTGTAACAAGAACTTTGATTCGCATGCATTTTGGCGCAAACACATTGTTGAAGTGCACAATTTTAATTGTCGTCAGGGTTTAAATTTTAGACAATTGGATATACATCATTATTTGTGCCTGGAATGCTATAAGAGGGTTACAGTTACACATACCAAGGGTGCTATAGGACAGCTGCAGTCCCATAAGTTCCGGCATTTACCCTATAGATCCTTTAAGTGCTTGACCTGCCATGGAGAATTTGTGCGCAAGCAAATGTTCTTTAAACATCTGAATCGCGATACTAACCGCTGTGACAGTCAACCGATCAATGCTCCGGAAAATTACGATGATGCAGAACAGAGGGAGAATCGGTCCGTAGTACCGGCTCTGGAGGATGTGGATCCTACCGCCTATCGTCTGATATGCCCGCAATGCGGCGATAAATTTAGTACCAGCAGCAAAGCGGTCTGGCGTGAGCATATTAATACACATCACGGACTGGGCAAGCGAGAGCTATTGCATATGCGCAGATTAGGAGAGGAGCTGTATCGCTGCACGGATTGTGAGGAGCAGCTGGCGACGAAGAAGCTGCGTTTGCTGCAACAGCATCGATTTAAGCACTTGCCCTATGCCGCTTATATACGCTGCCAGCTTTGTGAGCAACAGTCGGATGGACTGGATCATGCTAGTGCTGCAGCTGGTCTGCACAGTATGCGCGAATTGCAGCAACATATAAGGGATCAACACCCTACCGAGGCGGAGAATGATGAGCAAATGCAATCTCTATTAGATGGCGAGGATGAGGATAGTCAGCCAGTAAATAATGCGACTGGCAATGGTCGTTACATGCCGGTACCACCGCATTTGCTGGAAGATGATGTGGAGGATATGGAATTCGAGGAACAGTATCTACTGGGTTAA
Protein Sequence: MEGMDLWTSMFSSDYEEGEVDDRTRENNAYGDEFMGDEEEDQEADIDEATEEKGPDDDAIFDFELEPIVNISEAVPERAKRAVHLAPPMPVGAAVRPMHRQALHAPFGRGAAAAVGLAPAMRPTTSQINATDENGMPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQFNTRKGLNFVAIDKLYQRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCFICKREYKYRQDLMVHLRMVHCDEVIAMMRDSDGTAGRKTRVREPRTEPLHKAAPYPVPVEEAEINNERPAASAAEESFLGVDEPNHSSNHGKRKRMNILGNGNDGNGGTTSGSGSADICEDYIHYMCPDCGTDCDTLAQWNQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRTHKFSHLPQPDWMRCKLCYKGYTEHHELVTHLLKRHHLETLVPESIDEEPTASGNASINVIDDVEDNTDNGQFDDESSSQWDDAPRRGGRIGNDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLDKLNFEVISDRQLKCTECEKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKSSGAGGLSGSKLQPQRKQIVTVANETYEIIYLDEEQSPPNNNNINEENDFGEQMQDDDDFSCQLVPPPPAAAAVTSNSKANPNPNRYKCVDCGSLFPTQMALKEHISEEHDFTDTQYGAKTFDNAEATDDASPDLSSVPSSSKRSEINIAGVSTIEQNYIYLCPSCGKPYKTQFEWRRHINEAHNFDKRQYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERETSWREVLPKQGKDKDMSSGSSSPTHLAISGSSSLVGRSLKPQPGVLPIRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEVHNFNCRQGLNFRQLDIHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCHGEFVRKQMFFKHLNRDTNRCDSQPINAPENYDDAEQRENRSVVPALEDVDPTAYRLICPQCGDKFSTSSKAVWREHINTHHGLGKRELLHMRRLGEELYRCTDCEEQLATKKLRLLQQHRFKHLPYAAYIRCQLCEQQSDGLDHASAAAGLHSMRELQQHIRDQHPTEAENDEQMQSLLDGEDEDSQPVNNATGNGRYMPVPPHLLEDDVEDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -