Drel016412.1
Basic Information
- Insect
- Drosophila repletoides
- Gene Symbol
- -
- Assembly
- GCA_018150835.1
- Location
- JAECWQ010000089.1:18208626-18213765[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0021 0.15 12.6 0.4 1 23 144 166 144 166 0.98 2 15 5.7 4e+02 1.8 4.2 1 23 172 195 172 195 0.96 3 15 0.00012 0.0084 16.5 1.3 1 23 388 410 388 410 0.98 4 15 3.5 2.4e+02 2.4 0.5 1 23 416 439 416 439 0.89 5 15 0.46 32 5.2 1.4 1 23 464 487 464 487 0.96 6 15 0.0011 0.074 13.5 1.9 3 23 703 723 702 723 0.92 7 15 0.043 3 8.4 1.4 1 23 729 752 729 752 0.98 8 15 6.1 4.2e+02 1.7 1.8 2 23 789 810 788 811 0.91 9 15 0.0027 0.19 12.2 0.7 1 23 832 855 832 855 0.97 10 15 0.0059 0.41 11.2 0.6 1 23 1070 1093 1070 1093 0.90 11 15 0.0021 0.14 12.6 4.2 1 23 1106 1128 1106 1128 0.98 12 15 0.029 2 9.0 0.1 2 23 1134 1156 1133 1156 0.95 13 15 0.0015 0.1 13.0 4.4 2 23 1163 1187 1162 1187 0.90 14 15 0.041 2.9 8.5 0.6 1 23 1192 1214 1192 1214 0.97 15 15 0.0057 0.39 11.2 1.3 1 23 1220 1243 1220 1243 0.96
Sequence Information
- Coding Sequence
- ATGACGCACAAGCGTATGAAAACAGAACAAATGGAAATCAATTACAAATTTGCTTGTCGATGTTGCCTAAAATCCGAGGCAGAATTCTTCAAGCTGGACTCCCTAACAGACAGTGGCGGAACTGGCGTAGAAAAATATGATGCGTCTTCTAAAAAATTACCCCTTATACGTTTACTGCTATTCTGCATGCGCTCTGAAAAGAATATACCCGAGCTCCCGCAATACATTTGCGTGGATTGTAGCAAAAGTCTGCAAATTAGTTATTTTTTCATACAAAACGCTCAGCGAGCACACGAAATATTGTGCCACAAGTTGTGCCCCTCCAAGCTAACGAACTCAACGCGCCTCAATGGTCAGCAAGAACATACCCAACTGCCTGAGACGAATTACCAAAGTGACAAGCAGAAGCCGAAGCCAAATCCTTTGCGCCACGAATGCAAAGTATGCGGAGCAATTATCTACAATCGCTTGGATCTCAAACAGCACATACGCATGCACACAGAGGAATCGCGACATCGATGTAAACTGTGCACTTATGTTACTTTCAAGCAAAAATTGCTGCCTGAGCATTATCGCAAGACCCATGGCTTAACGGCTACACAAATAGAGCAGCAGCTAAAGATCAGGAAGTCATTGCAAGCGGCTGCCAATGCAACAAATACATCAGAGTCAGCAGTAGATGATGGGCAGGTACGAGTGTGCACAGTGGAAGACATGGAGTTGCTGATACCCACTGTACTGACACCAGAGGACTTTTCGCAGCCACAACTGGATGCAGATCAGCTGCGTGATATTGAGCAACAATTGGCCAAATCGGTATCAGTCTCTGGTTCCTCTAGCGCTGCCTTGCCGGCTGAACCGACGTTAGCGCCCGGCGGCAGTGGCAATATGAGCATCGGAGCTGAGTTTCTCGTCATGCCGGATGGCTCCTTGCAGCAAGTAAATGATGCTGGAGTTGTTTTTGAATACATTGATGATAGTAAAAGCGCGAATACCTCGACCAACATGAGCCTGCAAAGCCTGTTAAGTGACGTTAAAACAAATGTAACCTATGATACAATGAATATGGATATGAATCAGCTGGTAGTTCAGGAAGCACTGCCACAGATAACTGTAAGGCCAAAGCAAAGGCCTGGACCTGGTTCAATTGCCGCGTTAAAGCACAAATGCAAATTGTGTCCCAAAGCTTTTCCCACGGTGGCACGCCTTAAATCTCATCAGTTAACTCACAGTCATTTGCCTAAATTCTATTGCGATCAGTGCGCGTACTTCTCGCTACGCAGCTCTGATCTCATACAGCATTACACGGCAGAGCATAACTCAACTGTTAATGAGAGAAAAATAAATCATATGGAGAAGCCTACCTCTACAACGGATAGGAGTCGCATATATTCCTGCGATATGTGTCTATTCGAAACAGTCAGCTGCGGACAGCTTCGTGTACACTATAGCATTAAGCACCTAATACAACCCACTGAGGTGCAGCTTCGTCCCAGCTGGACCAATGATCCCAGGGAAAAGAACGCCAGCACGATATCGGCTACTAGTGATGGGTCCAATCTTTGTATACCTTTGGGTATTACATATCCACCAATGGCATCAGAGAAAACAACTGAAACGACACAAAAAACTACGACGACGACAACAATGGTGCAACAGCAGCAGCCGGGGCAGGCAACAACAACAGCCGTGTTAACGCCGGCTGGCGAAATTAATGTAGTTGTGGATGCCACATCATTGTTCTATTCAGGGGCTGCAGCTCGAAATGAAGCATCAACAATTACAACAGCAGCATCAGGAGATTCCAACACATTTGCAATATTTCCAGAGCAATCTTTTGCCAATACCCTTACAAAAACCAAAACGGGACCTCTAGCTGCTGGAGGTTCCTCTGTAGTGAATCCAAATAGCAGCATTTTTGGAGATATGCAAGAGTTCATAGATAATACCGATGTTGCAGCTATATGTACAATACCAGCAGACGATATGCCCGCAGTAGATGGAGATGATATTGTTATCGATAATAATAACATTAGTCTAGATTTTGATGCTGAGAATCTTTTCGATGACTTTGAAGAGGATGTGGAACATCTACAGAAGCCTTATTGCATATACTGTAACAAAAAGTTTACCAGCCAATACAAGTTCGAAAATCATATGTTTGTGCATCGAGGTTTGGCGCCCTATCGCTGTGAGCTCTGCACTAATTTATATAATATGAAGCGCTTGCTCATACGACATTACAAAACTGTGCACAAGCGCATGCCCACGCGGGACATGGTGCAGGCCAAAGGTGATAAAGTATCCGTTCCGTGTACAGCAATTGAAAAGCTGAATTTCAATGTGGACAAGCCTTCTATGCTGATGTGCGCTAAGTGTCCATTCGAATGCGAGTTGGAGAACGAGATGCGCAAGCATCTTAATGCGCATCACGGTATTAATGATGGAGTTTCTTTACATGCCAATGAGGTGTTTATTATACGCAAATTGCCCTATGAGTGCCCGCGCTGCATTCGTTCATTTGCGGCGAAGCGAACACTGACACGCCATTTGCAAAGGAGCCATTTAGTGGACACCATTATTGAGATGCAAGCGCCTCAATTGACAACTAGTTCAGCGGCGACAGCAACCACATCCACGGCAACAATCACATTGTCGAAGAATGCCAGCGATGTCAATAAAACAGCAGCAAAAACAACGCACAGTGAAGATGGCCCTGGCGACGGCGATGGCAATGGAAAATGCGTAGACAAAGCGGTAGACAAGGATGTTGGAATGGATTCGGGAAACTCAGATGCAAACGTAAATACCGGAATTTCACTAAAAAAAGACATAAACCTGGCAACAACAGCAAGAGCCAAAACAACAACTGCAGTTACGACCGAAGACTCAGCCGTAACAGAAGCCTCTCAACCAACTATAACAAAAACAGCAGCAACTTCGTCTGTGTCCACAACAACTACAGAAACTACACCAACAACAGCTGCAGAGCGGACCTCGCTCTTTCCAACGCCCACGCCATTTGATTTTGATCTGGACTTTATAGGAAATGGCGCACATGCCACACCTATTAAAACCAACAATGACAGTTTCAGCGTTGTGGCCAGCGCACATCAACTGTTAAATGGCAGCGATAAGCTGTTGTCTGCTGCATTAGAGCCATCGCCTGTCAAGGATTTACGTTCGCGCTTGCCACGTACGCCTATATTTGTATGTAAGCAGTGTAATCAGACATTTGACGAGCTGAGCAAGCTGCTACAGCACGAATCGGCGCAACATTCCAACGACACAGTTTCGCCTCGAAGCAGTCACCAGCATCAGTGCAAGATATGTAATAGCACGTACCGTACAGTGACATTGCTAAATTATCATATGAAAAAGCATGCGCCGCGAAAGCTGCAATGCAAGTTATGTCCCAAGGAATTTGAACTTAACTTGGATTTGGACGAGCACCTACAGTCGGAGCATCGCACGAAAATGCCTCTAAAATGTGGCATAGATGGCTGCAAGAAGACTTTTAATTTTAAGCACCATCTGAAGCGCCATCAGACAGCCTCGCATACCCGAGTGCAATATATATGTCCAGAGTGCGGTCGCGATATGTTGACCAGTTTGCATCTAAGGAATCATATGAGCAGCCACAAGGGTACCCATTCCTACAAGTGCCCGAAGTGTGTGCGTACCTATATGCGACGAAATCCTTTTCGCAGGCATGCACTACGTGAGCACCAATGGGAGCTGACTGATGCAGAAATAGATAAAATATATTCTGAAAATGACGCGCCTATCAAACGCGAACGAAGATCGCTGAGGGTTGAGAATGACCACTCTGATTAG
- Protein Sequence
- MTHKRMKTEQMEINYKFACRCCLKSEAEFFKLDSLTDSGGTGVEKYDASSKKLPLIRLLLFCMRSEKNIPELPQYICVDCSKSLQISYFFIQNAQRAHEILCHKLCPSKLTNSTRLNGQQEHTQLPETNYQSDKQKPKPNPLRHECKVCGAIIYNRLDLKQHIRMHTEESRHRCKLCTYVTFKQKLLPEHYRKTHGLTATQIEQQLKIRKSLQAAANATNTSESAVDDGQVRVCTVEDMELLIPTVLTPEDFSQPQLDADQLRDIEQQLAKSVSVSGSSSAALPAEPTLAPGGSGNMSIGAEFLVMPDGSLQQVNDAGVVFEYIDDSKSANTSTNMSLQSLLSDVKTNVTYDTMNMDMNQLVVQEALPQITVRPKQRPGPGSIAALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCAYFSLRSSDLIQHYTAEHNSTVNERKINHMEKPTSTTDRSRIYSCDMCLFETVSCGQLRVHYSIKHLIQPTEVQLRPSWTNDPREKNASTISATSDGSNLCIPLGITYPPMASEKTTETTQKTTTTTTMVQQQQPGQATTTAVLTPAGEINVVVDATSLFYSGAAARNEASTITTAASGDSNTFAIFPEQSFANTLTKTKTGPLAAGGSSVVNPNSSIFGDMQEFIDNTDVAAICTIPADDMPAVDGDDIVIDNNNISLDFDAENLFDDFEEDVEHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVPCTAIEKLNFNVDKPSMLMCAKCPFECELENEMRKHLNAHHGINDGVSLHANEVFIIRKLPYECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATATTSTATITLSKNASDVNKTAAKTTHSEDGPGDGDGNGKCVDKAVDKDVGMDSGNSDANVNTGISLKKDINLATTARAKTTTAVTTEDSAVTEASQPTITKTAATSSVSTTTTETTPTTAAERTSLFPTPTPFDFDLDFIGNGAHATPIKTNNDSFSVVASAHQLLNGSDKLLSAALEPSPVKDLRSRLPRTPIFVCKQCNQTFDELSKLLQHESAQHSNDTVSPRSSHQHQCKICNSTYRTVTLLNYHMKKHAPRKLQCKLCPKEFELNLDLDEHLQSEHRTKMPLKCGIDGCKKTFNFKHHLKRHQTASHTRVQYICPECGRDMLTSLHLRNHMSSHKGTHSYKCPKCVRTYMRRNPFRRHALREHQWELTDAEIDKIYSENDAPIKRERRSLRVENDHSD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -