Drel012109.1
Basic Information
- Insect
- Drosophila repletoides
- Gene Symbol
- -
- Assembly
- GCA_018150835.1
- Location
- JAECWQ010000100.1:18769277-18774992[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.037 2.5 8.7 0.2 1 23 979 1002 979 1002 0.94 2 13 3.3 2.3e+02 2.5 0.2 1 23 1162 1184 1162 1184 0.91 3 13 0.00013 0.0092 16.3 2.7 2 23 1187 1208 1187 1208 0.97 4 13 5.1e-05 0.0036 17.6 0.2 3 23 1216 1236 1214 1236 0.98 5 13 4.3e-07 3e-05 24.2 4.1 2 23 1243 1264 1242 1264 0.97 6 13 3.8 2.6e+02 2.3 0.4 5 23 1277 1295 1274 1295 0.95 7 13 1 69 4.1 5.4 3 23 1302 1323 1300 1323 0.93 8 13 0.11 7.4 7.2 0.2 2 23 1334 1354 1333 1354 0.96 9 13 4.1e-05 0.0028 18.0 0.4 1 19 1360 1378 1360 1382 0.95 10 13 1.2e-05 0.00081 19.7 0.5 1 23 1390 1412 1390 1412 0.98 11 13 7.7e-05 0.0053 17.1 7.6 1 23 1418 1440 1418 1441 0.96 12 13 0.00015 0.01 16.2 5.9 1 23 1446 1468 1446 1468 0.98 13 13 0.021 1.5 9.4 8.2 1 23 1474 1496 1474 1497 0.95
Sequence Information
- Coding Sequence
- ATGCAGTGCCCCGTGTGCACTTTGTACCTGCACGCGGGCATGAATCTCTCGGATCATTTGGAGACGCATCCCAAGGAGCAATACCCATATGGAGCAACGCTGCCTCCGCCGCCATTGCAGCTGTTTGCTGCACAGTCAACGGCAGTGCAGTCGCATCAGAAGCCACCGCCAGCCTATGGCGCCGCCATCAGTCAAATTCGATCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTTGCACCACCGAGTGGCAAACAGAGTAAAGTGCAAACGGAGATCTTTTTGAATCCACCGCCACCACCACCGCCGCCACAGTCGATGTTTTGTGCGTCGCCCTCGTCGTCATCTTCGTCTAGCTTCTCTTCAAGACTGCAACATCCTCAGCAACATCTACAACAACACCAACACCAGCACCAACAACAACAATGCCCAACTGGTAACAGTACACATGGTTCTGCATTAGCCAGCTGCTCCAGTTCATCCAGCTCAGCAGTACGTGCTAGCAGTCGCCAATCGAATAATTCTCCATTCGGTGCGCTCCTAAACGCCGCAGCTCAAGTTGCTTGCGCATCACCCTCCGCCTCGAGCGCCTCTGTTTTACGGTTTGCCGAATCCCCAGTGGCCCACTATCTGGAACGGGATAATGGCGACTTTATAGTCCAGGAAACGCCCAAACATATTGTCGAATGTGTAGAGAAAGATGATGGGGAATTCTCTGTAATTGAGCGGATTTATCAATCACCGCCCAGTGTCCTGCATATCCACGATGACGATGACGATGATGAGGAGGAGGACGTGGAACACGGGTGGGTCAACAGCGATGATGACGATCAAGTGAAGGTAATGAATAATCCAGTGGAGGATGGGGATGATGAGTTCGAAGACAGCCGCAGCAGAGTTTCCCTTAAAACGACAACAACGAAAAAGTCGCGCAAAACAAAACCGAGCGGACGAGTGCACAAACGAACCGCTGCTGCCACGAAGCAACAACAGCTGGTGACCACAACGGAGGATGAGGATGATTTCTTGAGCATAGGAAGCAGCTGTGCAGAGAGTGAACACTTCACAGAGCATCACCATCCGCAGCAGCAGCAGCATTCGTCACAGTTGGGAAGTAACTCGCAGCATCAACTTAGCACGTTGCCGTCGACGAGCAATGGTGCAGCTACCAGTAGCTCCTGTTCCGGTTCCAGTTCCATAAAGTCCAAGAAGAACCGTGTAACTGTTCTAAGTGATGTGCCGTTAAATATGAATGAATATCTGGATTTAGTGGGTAATATTGTAGCGTCAAGTCGCATAGGTGCAGCACGTCCGTTTGCCGCTGTGGCACCGATTCCCTTGGTCAAGGTGGAAAAAGAGGAACCGCTGGATGACGAGTTGCAGTCCCTGGAAGAAAAACCCAATTTAGATGCCTGTGGCAGTAGCAGCAGCAGCAGCAATGGGCATGGGACCACCAGCGTGATACGCATGGCTAGCACTAGCAGCATTGGTTGTGTTGAGGCTTATGTTGCCGCTGAAGGGGAGGATCTCACACAGCCGCCACCAGTTAAAATGGAGGTGGGACCAACAACATTGCTGCCACAACGTTATACAGCACCACCGCAGCAGCGTGGACCCAAGAAATTAGTCATAAAACCAAAGGCGACGGCGACAACCACACAAAAGACTGATAATAAAGGTGCTGCGCCAGTTGATCCACAGCAGATGCAGGTGCAAATAAAAAGCGAAAATGTAGAAGCAACCACATCAAGTGGCAGCATACTAGAGAAGCATCTCACCACAGCAGCCCGCAAGCACACCAACGTGAATGATGATGATGCGCGTGTTTTACTTGAATTTGCAAATTCAAAGCAGTTGCCGGCTGCTGGTGGCAGCAATCCTACCACATTTGTGGTGAATGCCGCCAGTTTTGCGTCCGCAGGCTCTGTATTTGCCAGCAGCACTGGGAAGAAACAAAGCAAACCGGGAGATGAATACATAATACCCGATAATAATAATTTGGATGTGGATGAAATTGTGATAAGCTCCTCCTTACAACAACAGCAACATGTTGCCAGCGAAGCCACCAATGCAGCAACATTGGCTTCCTCCTCAAGCAATTCCTCAGTTTTAGATCAGGAATGCTCCATGAACGCCACATTCCGTGTGGCCAAGCAAACCACATTGAGCGCCTGGTATCAACCAGAGGAGCAACAGCAGCCACAATCAGCGACGGGAGCAACAGCAACAGAAGAGCAGTCAAGCAATTTTATTGCAGCCCTCGCAGCAGTCGATTGTAGTGGAGCCCTGGACAGTGATGCCAGCGATGCCAAATATTTGGATCTGGATACCTGTAAACGGGAACAACTGAGCAATAGCAGCAACCATTTACCCTCTGCCTCTACCACATCCTCATCCTTCGCTGCTGCAGCCACAGAAAGCAGCCTGGTAGGTGGTCTGGGTTTGAATATACGTACTGATGAGAAGATGCCCGCCAAGGGTGAGATTTCAGAGCAGGAGAGCAATTGCGACATTGAGAACTCATGGAGTCAATCGATGTATGGGGACATATCACAGCGTTACTTTAGGAATCAATTTACGGATGGCTACAATCAACAATTGGCCGATTGGCGACATGTTTATTATCCACCAGAGGATCTCAGTGGCCAGCAACAGGAGGAACGGGAGCATAAACGTTTCGATTTCAATGCAGTCGCCTCGGATTACGCACAGGCGAGTGAGCTGGAGGCCTCTTCAAGCTCTGCTCGCAGCAATCATTTGATGGATGCACAACCCACCACGTCGACGTCTACATCGGCATTGCTGGCTGGTCCACCAATAGCCTCGACCTCCCGTGCTGCCGCCGAGGCAGAGGCAGCTGTGGCAGCGGCGCTGGCGCAAAGGAAACCACCGCGTCGCAAGATTTACAAGTGCCCGCACTGTGTGGCAATTTTCGAGAAGCTAAAGGAGAGGAATGCCCATATGATTGGGGAGCATAACTATGTGCGACAAAATCGTCGATTGATCTGTACCCAGGCGGTGGTTAATGCTGCATTGCTGGCGCAATCTCAGTCGCAGCTGCAGGTCCCACAGCAGCAGCAACTGTTGTTGCCGTCAACTGAGGAATTGCAGGAGGATTCTAAGGATGGTATTGTTAAGATAAAACAGGAGCATTGCCAGGAAAAACAGGATTCAACAGAACAGCTGCTGGGTAATCAATTAGAACTGCCAGATGTCAAGGATGCCGATCTTCTCGAGGCCAACGCTCAACCCCTGCCTGAAGCGGACATAAAGCCACCCAGTGGTGTCGCGGTTCTAGAGCAGAAACAGGCATTACCTCCGCTGGCCATGACCACGCCCGCTGCCAAATTGGCTGCTCTTTATCGCATGCTCATCGAATACAATGAATCCAAATTGGGTCAGGAACGCAACAATCTCAGCGAACTGGAACAGAAAGCCATGGAAAAGTCTATATTTCTATGCTACATCTGTCGTACCGATTTTCCCTCCGTTAAGCTCTATGATGCACATCTGACCGAGCATCCCGCTGAGTGTTTCACCTGCGGTAAGAAGTTCTATCGTTGGAAAAACTTCTCCCTTCATCTGAAGCGTCATCTCGGCTGGAAGGAGTTCGGCTGCTATGTCTGCGATAAGAAATTTGTTGTGCGTAGCGCCCTCGTCGAGCACATGCGGATGCACACCGGACAGAGTCCACTCAAGTGCAAAATATGCGGTAAAAAATTCAAGCGTTATTCCAACTTAACGCAGCATCGCAAGCGTCACATGAAAATGATGGTCCGCAAGAAGGAATATGTTTGCCACTGCGGGGAGGTGTTGCCCTCGAAGGCGCGTTTCCTGTGGCATAAGGAGACGCACGATCTGAAGCCGAAATGTTGTCCCTATTGTTGTGATCGCTTTGTACATGCAAATTCGTTGCGTCGTCATATTCGTCTGGCCCACTCGGATAAATTTGACTATGCCGAACCGATGGAGTGCCCCATGTGCAAGCAGATCTTTGCCAAGACCTCCATAAAGGCGCATATGGCCACGCACTCGACAGATCCGCAATACGACTGCGCTATATGCAACAAGAGCTTCTCCACAAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGCACGGCGAAACCTTTCAAATGCGAATACTGCCCCAAGGCTTTTGTAAGGGAATTGGACTTCAAGAACCACATGAATGCCCACAAGCAAATAAAGCCCTACACCTGTGAGTATTGCGGCTGCAAGTTCATCAGGAAATACAATTATATGCGGCATCGAAGGGAGCATCATGGTAACAAGAAGTTTACCTGCGATCAGTGCGACAAATCCTTCCATCGGCATTATTATCTGATTGAGCACAGGCGCATTCATACCGGAGAAAGACCCTTCCATTGCACGATCTGTGGCAAGAGTTCGACAACAAAGACCAATCATAATAAACATCTAAAAATACATCATTCGCGAGATCCTTTCACTGTGGAGGTTTAA
- Protein Sequence
- MQCPVCTLYLHAGMNLSDHLETHPKEQYPYGATLPPPPLQLFAAQSTAVQSHQKPPPAYGAAISQIRSXXXXXXXXXXXXXXXXXXXXLAPPSGKQSKVQTEIFLNPPPPPPPPQSMFCASPSSSSSSSFSSRLQHPQQHLQQHQHQHQQQQCPTGNSTHGSALASCSSSSSSAVRASSRQSNNSPFGALLNAAAQVACASPSASSASVLRFAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDDDDEEEDVEHGWVNSDDDDQVKVMNNPVEDGDDEFEDSRSRVSLKTTTTKKSRKTKPSGRVHKRTAAATKQQQLVTTTEDEDDFLSIGSSCAESEHFTEHHHPQQQQHSSQLGSNSQHQLSTLPSTSNGAATSSSCSGSSSIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLVKVEKEEPLDDELQSLEEKPNLDACGSSSSSSNGHGTTSVIRMASTSSIGCVEAYVAAEGEDLTQPPPVKMEVGPTTLLPQRYTAPPQQRGPKKLVIKPKATATTTQKTDNKGAAPVDPQQMQVQIKSENVEATTSSGSILEKHLTTAARKHTNVNDDDARVLLEFANSKQLPAAGGSNPTTFVVNAASFASAGSVFASSTGKKQSKPGDEYIIPDNNNLDVDEIVISSSLQQQQHVASEATNAATLASSSSNSSVLDQECSMNATFRVAKQTTLSAWYQPEEQQQPQSATGATATEEQSSNFIAALAAVDCSGALDSDASDAKYLDLDTCKREQLSNSSNHLPSASTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHVYYPPEDLSGQQQEEREHKRFDFNAVASDYAQASELEASSSSARSNHLMDAQPTTSTSTSALLAGPPIASTSRAAAEAEAAVAAALAQRKPPRRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQAVVNAALLAQSQSQLQVPQQQQLLLPSTEELQEDSKDGIVKIKQEHCQEKQDSTEQLLGNQLELPDVKDADLLEANAQPLPEADIKPPSGVAVLEQKQALPPLAMTTPAAKLAALYRMLIEYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQSPLKCKICGKKFKRYSNLTQHRKRHMKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -