Basic Information

Gene Symbol
-
Assembly
GCA_018150835.1
Location
JAECWQ010000225.1:13824296-13827732[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 5.1e-07 3.5e-05 23.9 3.1 3 23 103 124 102 124 0.98
2 11 0.0094 0.65 10.5 9.0 2 23 411 432 411 432 0.97
3 11 2.1e-06 0.00015 22.0 2.5 1 23 438 461 438 461 0.95
4 11 0.00065 0.045 14.2 0.7 1 23 466 489 466 489 0.96
5 11 5.6e-05 0.0039 17.5 5.5 1 23 507 529 507 529 0.96
6 11 0.00011 0.0078 16.6 1.6 1 23 534 556 534 556 0.98
7 11 2.9e-05 0.002 18.4 1.7 1 23 562 584 562 584 0.95
8 11 2.1e-05 0.0015 18.9 0.7 1 23 590 612 590 612 0.98
9 11 3e-07 2.1e-05 24.6 2.7 3 23 620 640 619 640 0.99
10 11 2.1e-08 1.4e-06 28.3 1.0 1 23 646 668 646 668 0.99
11 11 1.4 95 3.7 5.2 1 19 673 691 673 696 0.88

Sequence Information

Coding Sequence
ATGCCAGACACATATGGCCAATTCGATGCGGAACGCGTCTGTCGCGTCTGCCTGCGAGAAGTGGGCGATTTCTATTTCATTTATGACGAGGCGCCCGTCGAGCAAGGCGCTAATATAGCTCAGATACTTAACGAATGTACGAGGTATACGTGCGAGAGATATGATAAGATGCCGCATCATATGTGCGATAGCTGCATTAAGGCCGCCTGTCAGGCATATCGCTTTAAGAGGGATGCCGAGAAGGCCTATCGCTCCTTGGTAGCCATATTGGGCCGGACGCCACCTTCCAAACCCAATAGCAGCGATTGTAAAATCTGTGACCGCACCTTCTCACGCCGCGATCATATGCTGCGTCATATGCGAACTGTACACAAATTGGATGGCCGGCGCCGGACGCTGGCAGACCAGCAGAATGATCCAGCAACCTGGCCGAGCATTGATGAGACCACAATGCAGAGCATCGATGAATTGGAATCAGCTGAGGTTTTACTTCAAACTGACAACTTCACAGATGACGAGGATCCCAATGATCCCATTCAGCGTGGCTATCAATGTCATACCAATCCCATATCGAGCAATGAGGAGGGCGATGATGATGATGAGGCTGATGCCGAGGCAAAGCAATCATTGTGGCTACACATTAAACCAGAACCGGAACCAGAACCAACTGCTCAAGTAGAGGCAGTTCTTGAGTGCCCTGAGACAGCAGATGTTGCCCAGGTGAAGCGTGAGAAACGTGAAAAGCGGCGCAGAAAGGCTAATAAGGGCGATGAGCCCTTGCACTTGAGTGATGCTAGTGAGAGAGACAGAAAAGGCACTGCCAGATCCATTGCATTAATCACCACAGCAGAAGTCAAGGAGGAACCACTGGTTGGCGGTATTGATCATCATTTACCCATTAAGGAAGAGGAACAGCGGGCCAACGAGGACGATGAAGAGGAATTCGAGATGGAGGCCACAGCAGCGGACTTGCTACACAGCACAGATGATGAGGATGAGTTTGGCAATGATGGTGATAGCGATTCAAACAACGATGATAACGATGTCGAAGAAGATGATGATACAGACGAATACGAACCAGATTCACAGAGAAAGCCTGGGCCAAAATCTAAGCGTAAGCCGAAGCTCTTGAAGGTGGAAATTGTACGGGAGTATTTACAGAAACCAGGTAAGGGCAAGAGACGACGCCGACGCAATAAACAGGGTGAAGATGAAACCAATCCCGAGAATCGCTGCGAAGTGTGCCAGCGCACTTTTTCGCGTCATTGTCACTTGTTGCGCCACAAATTATCGCATCTAGAAAAGAAGCCGCATAACTGTCCCCATTGCCCCAAAGCATTTGCACGTAGCGATCATTTAAAGGCTCATGTTCTCAGCCTGCATGGCAGCAAGGAGCACAAGTGTCTGCTTTGCGATGCAGCCTTTACCCGTGTCGATGCCCTCGAGCGGCATAAGCTAAGCAAACACAATGGCGAAGGACTCGACGCCAATAGTGAACTAAAGTTGCAAATAAGTGAGCACACGTGCGAATATTGCTCCAAGCGTTTCTCCAGCAAGACGTACCTACGCAAGCATACCCTACTGCATACGGAGTTCCTTTATGCGTGCAAAAGTTGCGATGAAACCTTCAAGGAGCGCCAGCAGCTTCGCAGCCATGAGAAAACCCACACGGGTCAGCGTAATTTCCTTTGTTGTATCTGCGGCGACAGCTTCGCTCGCAATGATTATCTGCGAGTTCATATGAGACGTCACAATGGCGAAAAGCCCTACAAGTGCCGCTACTGCGTCAAGGCCTTTCCACGTGCTACAGATCTCAAGGTGCACGAACGTTATCACACCAACACCAAGCCGAATCTGTGCAATACATGCGGCAAGAGTTTCCATCGCGCCTACAATTTAACCATACATATGAGAACCCATACGGGTGAGCGTCCCTACAAGTGCGATCAGTGCCCCAAGAGCTTCAGTCAGAGTAATGACCTGAAGGCGCACATAAGACGTCACACAGGAGAACGTTACAAGTGTCCTCACTGCGATGCCTATTTCCTGCAGCTCTACCATATGCGCAATCATTGCCTTAGTGCCCATAATAAACATATTGAGACAAAAACCGGACGGCTGCAACGCACAGGGCTGTTGGATGAGTCTAACAACTCACATTTGACCACTGTGGTTATGCCGCCAGCACGTTTTCCACAGTCAGCCACTGATCAGGGACAGGGGCAGGCACTGGGTATTGCCACGGCCACAACGACGGCGCCAGAGGCGACAATTGCTACGCCCATTATAAATTCTCCCGTTACCTATAATACCACATCGCCTGCATCTGTAACGGTGCCAGTAACAGATGGGACCGGTACCGGCACCGGAAGCGGAGTCGGTTTTGTCAGTGCCGCAAGCAATGCCACAACAAGTGCATCGGCGCCCTTTAGTGCATTCAATATAACACCAGTCGTTATGGCTCATCTCATGTACAATCATGTTGGAGGGAACAGCCAGCAAAGCAATAGTAACGCCAGTGGCAGTGAGGCGGGTAAATAA
Protein Sequence
MPDTYGQFDAERVCRVCLREVGDFYFIYDEAPVEQGANIAQILNECTRYTCERYDKMPHHMCDSCIKAACQAYRFKRDAEKAYRSLVAILGRTPPSKPNSSDCKICDRTFSRRDHMLRHMRTVHKLDGRRRTLADQQNDPATWPSIDETTMQSIDELESAEVLLQTDNFTDDEDPNDPIQRGYQCHTNPISSNEEGDDDDEADAEAKQSLWLHIKPEPEPEPTAQVEAVLECPETADVAQVKREKREKRRRKANKGDEPLHLSDASERDRKGTARSIALITTAEVKEEPLVGGIDHHLPIKEEEQRANEDDEEEFEMEATAADLLHSTDDEDEFGNDGDSDSNNDDNDVEEDDDTDEYEPDSQRKPGPKSKRKPKLLKVEIVREYLQKPGKGKRRRRRNKQGEDETNPENRCEVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVLSLHGSKEHKCLLCDAAFTRVDALERHKLSKHNGEGLDANSELKLQISEHTCEYCSKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQQLRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTNTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDESNNSHLTTVVMPPARFPQSATDQGQGQALGIATATTTAPEATIATPIINSPVTYNTTSPASVTVPVTDGTGTGTGSGVGFVSAASNATTSASAPFSAFNITPVVMAHLMYNHVGGNSQQSNSNASGSEAGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-