Drel011545.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila repletoides
Gene Symbol
su(Hw)
Assembly
GCA_018150835.1
Location
JAECWQ010000100.1:14477964-14481089[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00062 0.043 14.2 2.2 1 20 227 246 227 248 0.94
2 12 2.5e-06 0.00017 21.8 0.4 3 23 299 320 297 320 0.93
3 12 0.011 0.79 10.2 0.1 1 23 326 348 326 348 0.96
4 12 7e-07 4.8e-05 23.5 2.5 1 21 355 375 355 376 0.95
5 12 5.7e-06 0.00039 20.6 1.0 2 23 388 409 387 409 0.96
6 12 9.7e-05 0.0067 16.8 5.3 1 23 420 442 420 442 0.99
7 12 7.5e-05 0.0052 17.1 0.9 1 23 448 470 448 470 0.97
8 12 1.5e-05 0.001 19.3 0.8 1 23 476 498 476 498 0.99
9 12 1.4e-06 9.5e-05 22.6 3.0 1 23 504 526 504 526 0.98
10 12 0.0069 0.48 10.9 3.5 1 23 530 552 530 552 0.97
11 12 0.0007 0.048 14.1 0.1 1 21 560 580 560 584 0.92
12 12 4.3e-05 0.003 17.9 0.3 3 23 604 625 602 625 0.96

Sequence Information

Coding Sequence
ATGAGCGAAGCGCCCGTCATCAAAATACTGGACGTTGAGCAACTGGCTCCCACACCCAAAGAGAAGCGTCCTGGCACCCGCATGAAACTGCTTAACGACGTGACGGGCAAGTCAGGAGCGGGGAGTCCACCAAAAGCAGTACAACGAGTCAAGCAGGAAAAACGCAATAGCATTAAAATACTCAACAATGACGAAACAACACCTAAAAGCAGTCCAGCAGGTAAAGGTGGCGGCTCCGCTTCTGCAGACAAGCGCAAAACTCCTTCGGCCGGTGTGAAAATCTTAAATGAGAAGCGTACTGTTCCAGTCGCAGCAGCCGTAGAAACGGCAAAGATCAAGACTTCACCTACGAAAAAGAAAGGCAAAATGGATCACTATGTGCTGCAGGCCATCAAAAGCGAGAATAGCAAGGCGGATAATAATAATACAACCAGCGTGGTAGTAGAAGATGAAGATACCATCGATTTTATCCTGGCCGAAAACGATGAGCTTGGACTGGGCGCTACCAAGGGGAGCGACAATGAATTTGTTGTCACGGGCATTGACGAGGAGGACGAAGAAGAGGAGGAGGACGATGATGATGATGATGATGCACTGATTGAGAGCGTAGGGACTAGCAGAGGCGGTGCAACTAATCGCAATAGTACCAACACTGGTGATCTTAAGGAAATGGTTGAGCACGTCTGCGGCAAGTGCTATAAGACTTTTCGACGCGTGAAGAGCTTGAAGAAACATTTGGAATTTTGCCGCTACGACAGCGGATATCATCTACGCAAGGCGGATATGATCAAGAATCTGGAGAAGATTGAAAGGGATGCAATCGTCATGGAGAAGAAGGATATTTGCTTCTGCTGCAGCGAGAGTTATGACACCTTTCATCTGGGCCACATTAATTGTCCGGATTGTCCGAAGTCTTTTAAGACACAGACTAGCTATGAGCGTCACATTTTCATTTCGCACTCGGAACTCAATGATTTTCCCTGCTCCATTTGTAATGCAAAGCTACGCAGCGCTGCGCTGCTCAAGCTGCACGAACAGCAGCATCAATCACGTGGCAAACCGTTTGCCTGCAAGATCTGTGGCAAGGACTTCACGCGCTCGTATCACTTAAAACGTCATCAGAAGTACTCCTCGTGCTCCGCGAATGAGAATGATACTATGAGCTGTAAGGTATGCGATCGTGTCTTCTATCGCCTGGACAATCTGCGATCGCATCTTAAGCAGCATCTGGGCACACAGGTGGTTAAGAAGCCAGAGTATATGTGCCATGTGTGTAAGAACTGCTTCTACAGTCTCTCTACGCTCAACATACACATACGCACTCACACGGGTGAGAAGCCTTTTGATTGCGATCTGTGCGATAAGAAGTTCTCCGCCTTGGTGGCGCTCAAGAAACATCGTCGATATCATACGGGCGAGAAACCGTACACCTGCACAGTATGCAGTCAATCGTTCGCTGTCAAGGAGGTGCTCAATCGCCACATGAAGAGACACACTGGCGAACGTCCACACAAGTGCAACGAATGCGGCAAGAGCTTCATACAGGCCACGCAACTACGCACGCATTCCAAAACGCATTTGCGTCCCTATTGCTGCTCCTTGTGCATCCAAAAGTTTAAGACGGAGAAGCAGCTGGAGCGCCATATAAAGGAGCACACTCGTCAGAAACGTCCGTCCTTTGCTTGTTCACAGTGCTCACGTGCTTACCGCACTAGCGCCCTGCTCAAGGAGCACATGGACGCCGGCGATCATTCTCCTGTTAAAGCTACTCGAGGAAAGCGCGCAGTGAAGATCATAGACCGTACTGACTGCGCTATTTGTGACAAGAACTTCGATAGCACTGAGACACTCAAAAATCATATACGCAGCGTGCACGAATGCAATCCCGATGATATATTTGGTACAAGCCCGCCACCGGCCAAGCGTAAGAGCAGAAAGTCTGTGGTAGTAGCACCACCAGAGCCTGAGGAGGGTGAGGTAATCGATGATGCTGAAGGAGAAACCGTGGCAGCAAACACATCTGCTGGCTCACTAATCTCTAGCAAAACCAATGACAATGGTGTAATGGTACGGGAGTTTCTGGTAGATGAAGGCGATGGCAGTGCACAAACCATTATGCTGGAAAATGAAGTTTATACCATTTTGCCATTGGAGGGTGATGGCGCCGCCGAAAAGGCACAGAAAACAGCTGGCGAAATCAAGCCAGAGTCTAAAGAGAAGCAATCTATCTCGCCGGTGGTCAAAAAGGAGCAGCGCAAATCCTTGGCCGCAAGCTTGGCTGCTGCCATTGCAGATAACCTGGACGAGCCGTCGAGCGATGATGATTTCAGTGGCGAGGTGCTTACCGAAGAGGATCTTAAGCTCAAGGAAAATATAGCCAAGTTAATTGATATGCTGGTAGATCCGCAAACTCTCAAGAAATACGGCTGGCCCAGCAGCTCTGTGGAGACGGTGTTGTGCAAAGTCATCGAGAATTGTGGCCACGATCTAACCAAGGGCGGAGAGAACTATGCCGAGTTGGATTACGGCAGTCGCATGCGTGAATATTGCAAGCTACTGTTCACAGTTGTCATACATAATGATTCCATAAAGTCGCTGTTAAATAATTTCCCCATTGACGATGTTATTGAATATGTATTGGGTGATGAGGATCAGGAACAAGAGCACCAAACGGAAAAGGATAAGGAGAAAGAGTTGGAATCCGACTCAGAAGAGAAAAAGTCGGCTACGGACACCACCGGACGGGAGATAGTTGAAGCCGAGGCTTAA
Protein Sequence
MSEAPVIKILDVEQLAPTPKEKRPGTRMKLLNDVTGKSGAGSPPKAVQRVKQEKRNSIKILNNDETTPKSSPAGKGGGSASADKRKTPSAGVKILNEKRTVPVAAAVETAKIKTSPTKKKGKMDHYVLQAIKSENSKADNNNTTSVVVEDEDTIDFILAENDELGLGATKGSDNEFVVTGIDEEDEEEEEDDDDDDDALIESVGTSRGGATNRNSTNTGDLKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMIKNLEKIERDAIVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFISHSELNDFPCSICNAKLRSAALLKLHEQQHQSRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYCCSLCIQKFKTEKQLERHIKEHTRQKRPSFACSQCSRAYRTSALLKEHMDAGDHSPVKATRGKRAVKIIDRTDCAICDKNFDSTETLKNHIRSVHECNPDDIFGTSPPPAKRKSRKSVVVAPPEPEEGEVIDDAEGETVAANTSAGSLISSKTNDNGVMVREFLVDEGDGSAQTIMLENEVYTILPLEGDGAAEKAQKTAGEIKPESKEKQSISPVVKKEQRKSLAASLAAAIADNLDEPSSDDDFSGEVLTEEDLKLKENIAKLIDMLVDPQTLKKYGWPSSSVETVLCKVIENCGHDLTKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEQEHQTEKDKEKELESDSEEKKSATDTTGREIVEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
-
80% Identity
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