Basic Information

Insect: Drosophila repleta
Gene Symbol: GLIS1
Assembly: GCA_018903745.1
Location: JAEIGN010000727.1:1417390-1424186[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.037 2.4 8.6 2.0 3 23 390 413 388 413 0.90

2 5 0.28 18 5.8 0.6 1 23 422 449 422 449 0.83

3 5 9e-07 5.8e-05 23.1 0.5 2 23 456 479 455 479 0.97

4 5 0.00073 0.047 14.0 0.8 3 23 487 509 485 509 0.92

5 5 3e-05 0.0019 18.3 0.4 1 23 515 539 515 539 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.037	2.4	8.6	2.0	3	23	390	413	388	413	0.90
2	5	0.28	18	5.8	0.6	1	23	422	449	422	449	0.83
3	5	9e-07	5.8e-05	23.1	0.5	2	23	456	479	455	479	0.97
4	5	0.00073	0.047	14.0	0.8	3	23	487	509	485	509	0.92
5	5	3e-05	0.0019	18.3	0.4	1	23	515	539	515	539	0.94

Sequence Information

Coding Sequence: ATGTCTGGCACAATGAAGTCACAGCAGCTGCCGCTGAGCATACCCGGCCAGTGCGACGAGCTGTTCGGCAAGCCGAAGCCGAATCTGGGCAAAGTCTACACCGAAAGCGTTTGCTACGATGCGTTCATGTCGCCGCCGCTGAGTGCGACGACCGGACACAGCGATCTGCCTTCAGCGGCGACTGCTGCGGCCGGCAAGCTGAATGCGAATAACACCTATTTCACCTGTGAGGAAATGCAGTTTCCGGACTTCTCGCACCTGTGCTTCGCCAGCGAAACGCCCAACTCGGCGTTCAGCGACTACAACAGCTACGCCGGCAGCTACGCCGAGCAGGATCGCGATGACATCGTCTGCGCCGTCTCGGAGCCCACCGGGATGCCCTATCAGCAGGGTCAGTACACGCAGCTCAACCGCGAGGATGTCTTCCGCTTCGAGCCGGAGGACATAGCCCGGCTAACGGCCGACAATCGGCCAAGTTGCACCTACGCCGAGCTCAATGGCCTCCTGCAGGTGCCCCAGACGCCGTACACACCGTGCAGTGCGCCGAGCCAGACGGTCAGTCAGGATATTGACTACTTCAACTACGACGAGGTGAACTGCCAGTCGAAGAATCAGTCTCCCTGCTCCTCGCCCCACCTGGACGCCTGGCTCAACTTCAATCTCAGCGAGCTAACAACAACAACAACAACAACAACTCAGGAGACATCGCCAAAGTTGTGCAACATTTACGAGCAGCCAATGGCGGCGATCAAGGGCGAGGAGCCCACGCAGAAGCTGCCCTCGATGAACTCGACCTTCGGCACGCCTCAGTGCGCGCCCATCGGCAATAACTACCCAGACTACTCCAATCTGCTGCAGGACGAAGCGATCTATGACTACACCAAAGAGTTTCCCACCGAAAACCTGGAGACTCACGTCGAGAAACCAAATCGTGAGCACAAGGTCATCTGGACCATCGAGGAGCTGGACGAGCTGGTGCTCAACGAGCAACAAAAACAACAGCAGTTGATCAAGCCTGAACTGCAGATTGTGCCCAGCGACGATGACAATGAGGAAGCTGATGATGCTGAGGAGGCTGAGATGGAGAAGTACGAGGATGAGGATCTGGACGACGTGTTCGCCATGCCCAAGCAGTGCGATCCGCTGGAGGAGTCTGTGCCGCTCATCTGCCGCTGGACCGACTGCAACATGGAGTTCACGCAGCAGCATCTCTTCGTCGAGCACATCGAGAAGTGCCACGTGGACGTGCGCAAGGGCGAGGACTTCTCCTGCTTCTGGCTCGACTGCTCCCGCCGCTACAAGCCCTTCAATGCGCGCTACAAGCTGCTCATCCACATGCGCGTGCACAGCGGCGAGAAGCCCAACAAATGTCCGTTTCCGGGCTGCAATAAAGCGTTTTCACGTCTCGAAAATTTGAAAATTCATCAGCGCTCGCACACAGGTGAGCGGCCTTATGGCTGTCAATATAAAGGTTGCCTTAAAGCGTTCAGCAATAGCTCGGATCGTGCGAAACATCAAAGAACACACTACGATACGAAGCCATATGCGTGTCAGCTGCCGGGCTGCACCAAGCGGTACACGGATCCTTCCAGCCTGCGCAAGCACGTGAAGAATCACGGACTCTTGCGCCGGAAGTCGGCGAGCTCCGTTGCCAGTGGCTGTGGCCGCAAGGCAGCTAAGACGCGGCGCAACTCGGAGTCGGCTGTGGCCGCCAAGGAGGCGGGTGAGCAGCGGACGCAGCGCAGCAGCAGCTGCAGCGAGGCGACGCAGCCGATGCAGTTCGAGGCACCACAGAGTCTGCCAAACCCATCCGAAACCCGCAATGGAATCAAATTTAATGAGCTGTCCAATTGCATTGTCATCGTGGAGCAGAGTCAAAGCGAAACGAGAGCTGAGAGCCACCTGGCGGCCAACTACGACAACTTCAACTGTTACATGGCCAAAGCCGAGCCGGAAGCCGTCAACATTTATGCGGCGAGCGAGGCGCGTGACCAAAGCTACGATGAGAATCTGCAAAAGTTCAACGAACTGGAGCAGTTGCTGCCTGGCGAGCTGCAGAGTGCAGGCGTGGCCTTCGACGCGGACGCCACCAAGTGCCAGCTGAGCGAATTCGTGTCCTTCGAATATGTGCGAAAGTATCTGACGGATGCCTACGATCAGCCCACGGCCAAGAGACCAAAGAGTCCGCTGGACAATAACCAAATTGAAACCGATTTCCAGAACTATGATCTTCAGTTCATATAA
Protein Sequence: MSGTMKSQQLPLSIPGQCDELFGKPKPNLGKVYTESVCYDAFMSPPLSATTGHSDLPSAATAAAGKLNANNTYFTCEEMQFPDFSHLCFASETPNSAFSDYNSYAGSYAEQDRDDIVCAVSEPTGMPYQQGQYTQLNREDVFRFEPEDIARLTADNRPSCTYAELNGLLQVPQTPYTPCSAPSQTVSQDIDYFNYDEVNCQSKNQSPCSSPHLDAWLNFNLSELTTTTTTTTQETSPKLCNIYEQPMAAIKGEEPTQKLPSMNSTFGTPQCAPIGNNYPDYSNLLQDEAIYDYTKEFPTENLETHVEKPNREHKVIWTIEELDELVLNEQQKQQQLIKPELQIVPSDDDNEEADDAEEAEMEKYEDEDLDDVFAMPKQCDPLEESVPLICRWTDCNMEFTQQHLFVEHIEKCHVDVRKGEDFSCFWLDCSRRYKPFNARYKLLIHMRVHSGEKPNKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDTKPYACQLPGCTKRYTDPSSLRKHVKNHGLLRRKSASSVASGCGRKAAKTRRNSESAVAAKEAGEQRTQRSSSCSEATQPMQFEAPQSLPNPSETRNGIKFNELSNCIVIVEQSQSETRAESHLAANYDNFNCYMAKAEPEAVNIYAASEARDQSYDENLQKFNELEQLLPGELQSAGVAFDADATKCQLSEFVSFEYVRKYLTDAYDQPTAKRPKSPLDNNQIETDFQNYDLQFI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00516566;
90% Identity: iTF_00568547;
80% Identity: -