Basic Information

Insect: Drosophila repleta
Gene Symbol: RREB1
Assembly: GCA_018903745.1
Location: JAEIGN010000233.1:6919148-6921608[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 1.3e-05 0.00081 19.5 0.4 1 23 442 464 442 464 0.99

2 6 0.0058 0.37 11.1 0.7 2 23 477 498 476 498 0.96

3 6 3.1e-06 0.0002 21.4 0.7 1 23 504 526 504 526 0.99

4 6 4.2e-06 0.00027 21.0 3.8 1 23 532 555 532 555 0.96

5 6 0.0011 0.071 13.4 5.2 1 23 562 584 562 584 0.94

6 6 1.2e-05 0.00076 19.6 0.3 1 23 589 612 589 612 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	1.3e-05	0.00081	19.5	0.4	1	23	442	464	442	464	0.99
2	6	0.0058	0.37	11.1	0.7	2	23	477	498	476	498	0.96
3	6	3.1e-06	0.0002	21.4	0.7	1	23	504	526	504	526	0.99
4	6	4.2e-06	0.00027	21.0	3.8	1	23	532	555	532	555	0.96
5	6	0.0011	0.071	13.4	5.2	1	23	562	584	562	584	0.94
6	6	1.2e-05	0.00076	19.6	0.3	1	23	589	612	589	612	0.95

Sequence Information

Coding Sequence: ATGTTGACTACAAAACAATATCTTCCAGATATAGAGAAGTGGTGTCGCCTGTGCCTAAAGGATCTTAAAAATCCGCACACAATCTTCGCTGAGGACGACACACAGCCATCAATACCGATGCGCCTGATGGCTTGCCTCTCCCTGGAGGCAAAGTCAACTGACGGATTGCCGAAAAAGATCTGCGGAGATTGTCGTTACCAGTTGGAGAAATCGTTTCTCTTTCGCTTGCGCAGCCAGGCGGCTGACAAGAAACTCCGCAAGCACATCCGGCAGGTCAGTATGGGTAAAAAGAGTCGCGTCTTTGCCAAATCATTGGATAACGAATCCGACGAGGAGGAGTTCGAAGAATCCATGGCGTTTATAGAAAAACTGGAAGTGCCGTTCGAAAAAAACACTGAAAAATGGCGGGAGAAGTGCAAGGAGGATATGGAAAAGATTTTTGAGAGTCGTCTTCAATCCGCGCGCGAAGAGCTCTCCATCGAAATGCGCAAACAACTCGCCGATGAGGTGCAAAGTGATGTGCGTCAGCAGCTACGTGACGAAATGCAAGAGGAGAGCCGCAAGGAACAGCTCGCCAAGCTACTGGGCGAACTGGAGGTTTTCTTGGCCGAGAAGAAAGCCGGCCTCTGGGAACCATTGACGGAGCTGCCCGCTGACCCAAAGTCGATAAACGAATCCCTTGTGCAAGCACCAGCTGCACCAGCACCAGCCCTCATGTCCTTGCCAGCCAGTGACAAGCGTGTAACCCGTAAACGTGGTCGCATCTCATCACCTGCAGCGAATCTGAATCGGCGATCCAAAGTCTCTGTTAGTGAAAGCGCGGAATATGTGCTTGGAACCGATTCCAAGGTGGAAGTACTCACCGCGGATGATGCGGACTTCGATGCATCTGCGCAAGACACCAACGAGAGCTTTAGTGATGTCAAAATGCTCGGTTCTGGTGAAGTGGTGACCAGCCAAAATGGCGAGATCTACATTATAAATGCCGCTGCGTCAGCGAACTCGACGCCCAGCTCCTCGGCAGAATTTCAGCAGGAGAAAAACATCACCTCATACAATATCAAGGACAATGGCGAGATCCAGTTTACGGACGCCAAGTCTGACGAAATCGGGGACGTAGTGGTATTTGATCTCGACGATGAAGGCGGCGACGATCAGCAGATATATGAACTAGACGACAATGTCATAATAGTGCAGTCGGACGAAAAGACAAACAGCGATGGCCAGACCTCGGACAAGAGTACAAAAAGTGATTTTGTGGTGAAGCGAACTCCACGCACCTCCGCGCCAATTGTTGGACGAGCCAGCGATACACTGAAAACGTTTCAGTGCCAGCTGTGCCCCGTTGTGTTTGCCACGGAGAAGACATTGTCGCGCCATCTGAACACGCACATCAAGGCGCTAAAGAATGGCACAGACGGCGCCCTTAAGTGTCCCGTGTGTCAGTTGCAGTTGTCCTGCGCCAGTTCGCTGAAGCGTCATATGATCATTCATACGGGTCGAAAGCCGTATAAATGCGGCGAGTGCGATTCGTCCTTTTCACAGCGTGAGGTGCTCAAGCGTCACATGGACACGCATACAGGAGAGAGGCGCCATCGTTGCCCCCACTGCGAAACTAGCTTCGCTCAGAAGACCAATCTACAGCAGCACATCAGCCGCATGCACATGTTCGGCGAGCAGCAGCACAAGTGTCACCTTTGCAAGCGCAGCTTCAACCATGTCTCGGGCCTGAGTCGTCACCTTGTCGCCCACGCAGGCGTCACGTATGCCTGCAAAGAGTGCGGACGCCAGTTCAACGACCGCAGCGCTGTGAAGCGACACGTCCAGAACGTGCACAAGAGCAAGGACACTGGCGGGGACTCCCCAACGGACGGCAATGGAAATGAAATGGAGTTTGAATAA
Protein Sequence: MLTTKQYLPDIEKWCRLCLKDLKNPHTIFAEDDTQPSIPMRLMACLSLEAKSTDGLPKKICGDCRYQLEKSFLFRLRSQAADKKLRKHIRQVSMGKKSRVFAKSLDNESDEEEFEESMAFIEKLEVPFEKNTEKWREKCKEDMEKIFESRLQSAREELSIEMRKQLADEVQSDVRQQLRDEMQEESRKEQLAKLLGELEVFLAEKKAGLWEPLTELPADPKSINESLVQAPAAPAPALMSLPASDKRVTRKRGRISSPAANLNRRSKVSVSESAEYVLGTDSKVEVLTADDADFDASAQDTNESFSDVKMLGSGEVVTSQNGEIYIINAAASANSTPSSSAEFQQEKNITSYNIKDNGEIQFTDAKSDEIGDVVVFDLDDEGGDDQQIYELDDNVIIVQSDEKTNSDGQTSDKSTKSDFVVKRTPRTSAPIVGRASDTLKTFQCQLCPVVFATEKTLSRHLNTHIKALKNGTDGALKCPVCQLQLSCASSLKRHMIIHTGRKPYKCGECDSSFSQREVLKRHMDTHTGERRHRCPHCETSFAQKTNLQQHISRMHMFGEQQHKCHLCKRSFNHVSGLSRHLVAHAGVTYACKECGRQFNDRSAVKRHVQNVHKSKDTGGDSPTDGNGNEMEFE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00568487; iTF_00510038; iTF_00573558;
90% Identity: iTF_00568487;
80% Identity: -