Drep009266.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila repleta
Gene Symbol
-
Assembly
GCA_018903745.1
Location
JAEIGN010000753.1:6024250-6026753[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.035 2.3 8.7 5.4 3 23 232 252 230 252 0.96
2 12 0.00025 0.016 15.4 2.0 2 23 259 283 258 283 0.92
3 12 0.00032 0.02 15.1 1.1 1 23 290 315 290 315 0.93
4 12 3.6e-05 0.0023 18.1 3.0 1 23 325 347 325 347 0.97
5 12 0.00011 0.0072 16.5 0.9 3 23 356 376 354 376 0.97
6 12 0.0064 0.41 11.0 0.5 1 23 382 404 382 404 0.97
7 12 0.05 3.2 8.2 4.7 1 23 410 433 410 433 0.97
8 12 0.032 2 8.8 3.7 1 23 439 461 439 461 0.94
9 12 0.0047 0.3 11.4 0.7 2 23 468 489 468 489 0.97
10 12 0.00015 0.0098 16.1 0.8 1 23 576 599 576 599 0.96
11 12 0.0085 0.54 10.6 3.1 1 23 605 627 605 627 0.95
12 12 3.5e-06 0.00022 21.3 2.6 3 23 635 655 633 655 0.97

Sequence Information

Coding Sequence
ATGGATGAGGACAACCCAGTTTCCATACATGCAATATGCCGCACTTGCCTGTCAACATTACAGCACTTTGCGGCCTACGATCTGTTTGTGGTTCCAGGTCTGGCCAAGAAACTGTGTGTGTGCACCTCGCTCTCGGTGGAGCAACAGGATGGATTTCCAAAATGCATCTGCATAAATTGCTACATCCGGCTAAACGATTTACATAATTTTCAGAAACAATGTGTGGACTCTTCTGCCAAGTTAAGAGATATGTTGGACAACAATTGCTTGGATATCCCGGCTTACTGTGCAGAGAACATTGTTGTAGTAAATGCTGCCCTACAGCAGGATAATGACATTGATGTGCCACAAGATATAGACGTGCCCATTGAAGATGAAGACCGCATTAACTTTGATCCACTACTTAACACCAAAATAGAGATTATTGATAATGAGGATGATGTGTTTAGAATGATAGAAAATGTTGATAAAGACGAGAATGAGGCTCAGCAGGACCAGGACTACTGCAGTCAAAGCGAACTTATTCAAGATAACGACTCTGACGATGCCATGCCTCTGTCACGTTTACGGAGCTCACAAAGAAAGAGAAAGAATAATACTGCAAGTGAAGTGGACATGAATGAAGCGAGCTTATCCAAGCGGAAAGCAAATACCAAACGTGGTGCTGCGGCTAAGCGAGAGCTTTATATCGATTGTCATATATGCCACCAGAAGTTCACAAGTGAAATTCGCTACGAGGAGCATATGAAGCATCACAACGATCTCCTGCCCGTCCAATGCAGTGTGGAAACATGCAAAAAGCGTTTTACGAATGCCGCTAGCCTTCAACATCATATGGATCACGCTCACCTGGAGCTGTGCGAACTGCACGCCTGCACTGTTGAAGGATGCGATAAGTCATTTCCTCGTACGCGTATGCTCACGCTTCACCTAAAAAAGATGCACAACATATGCAAGCCTGAGAACCCCATTCATCCCTGCCCAGATTGTGATAAGGTCTTTCGTTGTCCAACGGCGCTTAAGAAGCACATGTATAAACACACTGGCGAGGAGCTGCCCATTGCCTGCAACATCTGCGACAAACGCTTCCACATCAACAGCGAGCTCAGAGACCATCTCCTTCGACATGCCGGCGTCAAGAATCACGTTTGTCCTTACTGTGGTGTGGGCAAGACGACTCGCCAGGAGTGGAACAAGCATATATTGACGCACACCAAGGAAAAGCAGTTTCAGTGTCGACATTGCGAGCACTCGACCCACAACAAACAAGCTCTGGCCAATCATGTCAAGGTAGTCCACTTGAAGATCAAGAACTTCGCCTGTCAGTACTGCGGCAAGACATTTGGGAAACTGCACGCCTGTAAGGTTCACGAGAGACTCCACACGCGCGAGAATTGCCGCGAGTGCAAGATCTGTGGCAAGATCTTCCTCTTCGAGAAGCGTTTGACGAAGCATTTGCAGATCCACGAGAAGCGTGAAGTCAAAGCAAATAATGTCAAAACCAAAGCTAACGAGGCCGATCAGAATGATACAAATTTGAATCAGGAGTCAGCAGCACCGGAAGACGCGCAACCCGAGGCTGCATCTGCTGCCAAGCCGAAAACTTCACACAGAGTTGAGCGTGTGGAACTGTCTCAACTGGCGGGCACCTCTGTCAATCCAATTCCATCAGTTTCCGTGCCATCCTGGTCACCGCAGGTGAACTTCACTAAAAAAGAGGGCCAGCACATTTGTCCAGGCTGCGGGCGTGGCTTCAACCACATTGGCAATATGAAACTCCACTATAAGGTCGTCCATGACAAGATCAAGGACTTCGCCTGTCGCTTTTGTCCCAAGCGCTTTGGCAAAGCGCAATATCTGCGTCATCATGAATACACGCATACGGGTGAGCGGCCGTACGGCTGCAAGTTGTGCGATAAGAACTTCAGCCACGAATCCTCGCTGCGCAAGCACATGATTTCACACACCAGGCCCCCAAAAGTACCAAAGGCTCCGAAGGCCACAGCTCCGAAAAGAGAAAATCAGAGGCCTAAAATCGAGCTGAATAAGCGTCAACCAAAGAATTATGAGCAGTATCAGGATCCGGCAGCAGAGCGGGCTGCAGCTACTGCCGAGTTATTTGCCCAGAAGATCGAGGAGAGCGAAGCCAAGCAAAGGGCAGAGGACAAAATTCGAAAGATTCAAGAAGCTGCGTGCGAGCAGCTGCAGAAGCTCCAAAGGGAACAGCTGATTGAAAAAGTATCCAACGACAGCTTTCAAGTAGGAAACTCTGAGACTGCCACAAGAGTGGATGCTCTCAAAGCAGATCCATTATAA
Protein Sequence
MDEDNPVSIHAICRTCLSTLQHFAAYDLFVVPGLAKKLCVCTSLSVEQQDGFPKCICINCYIRLNDLHNFQKQCVDSSAKLRDMLDNNCLDIPAYCAENIVVVNAALQQDNDIDVPQDIDVPIEDEDRINFDPLLNTKIEIIDNEDDVFRMIENVDKDENEAQQDQDYCSQSELIQDNDSDDAMPLSRLRSSQRKRKNNTASEVDMNEASLSKRKANTKRGAAAKRELYIDCHICHQKFTSEIRYEEHMKHHNDLLPVQCSVETCKKRFTNAASLQHHMDHAHLELCELHACTVEGCDKSFPRTRMLTLHLKKMHNICKPENPIHPCPDCDKVFRCPTALKKHMYKHTGEELPIACNICDKRFHINSELRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCRHCEHSTHNKQALANHVKVVHLKIKNFACQYCGKTFGKLHACKVHERLHTRENCRECKICGKIFLFEKRLTKHLQIHEKREVKANNVKTKANEADQNDTNLNQESAAPEDAQPEAASAAKPKTSHRVERVELSQLAGTSVNPIPSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKVVHDKIKDFACRFCPKRFGKAQYLRHHEYTHTGERPYGCKLCDKNFSHESSLRKHMISHTRPPKVPKAPKATAPKRENQRPKIELNKRQPKNYEQYQDPAAERAAATAELFAQKIEESEAKQRAEDKIRKIQEAACEQLQKLQREQLIEKVSNDSFQVGNSETATRVDALKADPL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00568451; iTF_00573541; iTF_00520137; iTF_00493897; iTF_00502748; iTF_00510017; iTF_00554597; iTF_00559688; iTF_00532588; iTF_00479694; iTF_00549765; iTF_00540590; iTF_00473297; iTF_00599803;
90% Identity
-
80% Identity
-