Basic Information

Insect: Drosophila repleta
Gene Symbol: -
Assembly: GCA_018903745.1
Location: JAEIGN010000497.1:15024827-15027482[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.07 4.5 7.7 1.1 1 23 386 408 386 408 0.95

2 7 9.8e-06 0.00063 19.9 1.1 1 23 414 436 414 436 0.98

3 7 1.7e-06 0.00011 22.3 0.2 1 23 442 464 442 464 0.98

4 7 9.1e-07 5.9e-05 23.1 1.2 1 23 470 492 470 492 0.98

5 7 0.00027 0.018 15.3 1.8 1 23 498 520 498 520 0.97

6 7 2.9e-06 0.00019 21.5 2.4 3 23 528 548 526 548 0.94

7 7 8.6e-06 0.00056 20.0 0.3 1 23 554 577 554 577 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.07	4.5	7.7	1.1	1	23	386	408	386	408	0.95
2	7	9.8e-06	0.00063	19.9	1.1	1	23	414	436	414	436	0.98
3	7	1.7e-06	0.00011	22.3	0.2	1	23	442	464	442	464	0.98
4	7	9.1e-07	5.9e-05	23.1	1.2	1	23	470	492	470	492	0.98
5	7	0.00027	0.018	15.3	1.8	1	23	498	520	498	520	0.97
6	7	2.9e-06	0.00019	21.5	2.4	3	23	528	548	526	548	0.94
7	7	8.6e-06	0.00056	20.0	0.3	1	23	554	577	554	577	0.98

Sequence Information

Coding Sequence: ATGCCGCCCAATTCGCCCACCAGCAGCGTGGCTAGCAGCATTGACCTGAAGCTGCGCACGCGTCGCGAGCTGGAGCGCAATCGCGAATTCGTCTGCTCGCTGCTGGTGGCCTATGAGCGCAGCGAGAAGCTCTGGAATCCCAAGCATCCCGACTACAAATACAACGCGAATCGCAGTGTCTACAACGAGCTGGCCGCACCCTTGCAGGCCGTCTTTCAGCTGCCCTTAACGGGCGCCGAGATCTTTGCCGTGCTGAAGGAGCTGCGCGGTCGCTATCGGCGGGAGCTGAGCAAACTCAATGCGCTGGGCGGCAAATACAAGTCGCGGCTGTGGTACTTCGAGAAGATGCACTTTCTGCGCGGCGTCATTGAGGCCAAGCGAGCGGAGCGGGAGGCGAAGAGCGAATCAGCGGAGAGCGAAAAGTCCAGTGAAACCGACAGCGAGTCGACGACGAAGTCAGCGCAATATCGTGAGGTGCTCAGCTGTTTGATCGATGGCTTCAGGCGTAAGGAGAGCCTGTGGAATCCGCAGCACTTTGACTACAACAGCTGTTGCAAGAAGGAGCTATATCGGGAGATATCAGCTGAGCTGCTGGAGGAGCTCAACTACGAGATGAGTGGCGACGACTGCTACAAGGAGCTGCAGAAGCTGCGCACGCGCTATCGCAAGGAGCTGCGCATGGTCATCAAGCACAAGGGTCTCTACCTGCCCAAGCTGTGGTGCTACGACGAGCTCGACTTTCTGCAAAAGATACTACAGGATCAGATCTTCAATAAGATGAGCAAGAAAAAGGGAGTGGTGGAATCGTATCGTCGCACCAAGTTCATTGATGCCAGCAGCATTAGCTTCGCGCTGCAGGACGATCAGCTGCAGTTTGTGGAGATCTATCGGAACTATCCAGCCCTCTGGGATGTCGATCATCCCGACTTCCGCTCGAATGCCTATCGCACGCAGGCCCTGGGCCAGATGCTCGAGGAGCTCAACACGACGTTTCAGTGCGCCTACAGCACAGCCGAGCTGGAGAAGACTTTGTTCGAGTTGCGCAAGGATTTCTCAGCGCAGAAACGCAAGATACTGACAAATGCCTCGGGCTGCAGCAGCATTTCCTTGCTGCATGCGAAACTCGGGCAGTTCCTCGAACCGAATCTGGGTCCCTTTCGCTGCGATGTGTGCAGCGAGCTGGTGAAGACCTGCGATCAGTACAAGGTGCATCGAGCGGCGCACGACGGCACGCAGCCCTTCATTTGCACGCTGTGCGGCAAGGGCTTCCAAATGCCCTGCAACCTGACGGTGCACATCCGGCGGCATCGACGCGACTTTCCCTATGCCTGCGAGCAGTGCGACAAGCGCTTCGCCACCTCCACCGAGGTGGCCATACACATGCGCACGCACACCGGCGAGCGGCCCTACATCTGTGATCTGTGCGGCAAGTCCTTCAAGACGTGGTCCTTCTTCGACATACATCGACGCACGCATCTGAACCAGTCGTCGTTCCACTGCCCCATCTGCGACAAGGGCTTCTATGAGAAGAACCGCTTCACCGACCACATGAACGCCCATCTGAATATCCGCAAGCATTTGTGCACCGTTTGCGGCAAGACCTTCACCACATACGGCAACCTCAAGAAGCACACCGAACTCCATCTGGCCGTGAAGAAGTACAAGTGTGGAGCTTGTGGCAAGCGCTTTGCACAGCTCGCCAGCTTGCGTTGGCACAGAAAACGTGAACACTCTTCTGAGCAGCCGCAGCAGCAGCAGGAGGAAGAGGAAGAGGAGCAGCAGCAGCAGCAGCTGGAGGAGGAGGTGGAACTGGAAGTCGAGCAGCAGCCAAGCCAAGACTCTCCATCAGCCGTCTAA
Protein Sequence: MPPNSPTSSVASSIDLKLRTRRELERNREFVCSLLVAYERSEKLWNPKHPDYKYNANRSVYNELAAPLQAVFQLPLTGAEIFAVLKELRGRYRRELSKLNALGGKYKSRLWYFEKMHFLRGVIEAKRAEREAKSESAESEKSSETDSESTTKSAQYREVLSCLIDGFRRKESLWNPQHFDYNSCCKKELYREISAELLEELNYEMSGDDCYKELQKLRTRYRKELRMVIKHKGLYLPKLWCYDELDFLQKILQDQIFNKMSKKKGVVESYRRTKFIDASSISFALQDDQLQFVEIYRNYPALWDVDHPDFRSNAYRTQALGQMLEELNTTFQCAYSTAELEKTLFELRKDFSAQKRKILTNASGCSSISLLHAKLGQFLEPNLGPFRCDVCSELVKTCDQYKVHRAAHDGTQPFICTLCGKGFQMPCNLTVHIRRHRRDFPYACEQCDKRFATSTEVAIHMRTHTGERPYICDLCGKSFKTWSFFDIHRRTHLNQSSFHCPICDKGFYEKNRFTDHMNAHLNIRKHLCTVCGKTFTTYGNLKKHTELHLAVKKYKCGACGKRFAQLASLRWHRKREHSSEQPQQQQEEEEEEQQQQQLEEEVELEVEQQPSQDSPSAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00516449;
90% Identity: iTF_00599763;
80% Identity: -