Basic Information

Insect: Drosophila repleta
Gene Symbol: salm
Assembly: GCA_018903745.1
Location: JAEIGN010000556.1:937039-953819[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 2.2e-06 0.00014 21.9 1.7 1 23 347 369 347 369 0.98

2 8 3e-05 0.0019 18.3 3.5 1 23 375 397 375 397 0.98

3 8 2.1 1.3e+02 3.1 2.5 5 23 642 660 639 660 0.84

4 8 3.1e-08 2e-06 27.7 0.2 1 23 666 688 666 688 0.98

5 8 0.00095 0.061 13.6 0.9 1 23 698 720 698 720 0.98

6 8 0.048 3.1 8.3 0.1 2 23 940 962 940 962 0.96

7 8 1e-05 0.00066 19.8 5.0 1 23 1095 1117 1095 1117 0.96

8 8 8.2e-08 5.2e-06 26.4 0.7 1 23 1123 1145 1123 1145 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	2.2e-06	0.00014	21.9	1.7	1	23	347	369	347	369	0.98
2	8	3e-05	0.0019	18.3	3.5	1	23	375	397	375	397	0.98
3	8	2.1	1.3e+02	3.1	2.5	5	23	642	660	639	660	0.84
4	8	3.1e-08	2e-06	27.7	0.2	1	23	666	688	666	688	0.98
5	8	0.00095	0.061	13.6	0.9	1	23	698	720	698	720	0.98
6	8	0.048	3.1	8.3	0.1	2	23	940	962	940	962	0.96
7	8	1e-05	0.00066	19.8	5.0	1	23	1095	1117	1095	1117	0.96
8	8	8.2e-08	5.2e-06	26.4	0.7	1	23	1123	1145	1123	1145	0.98

Sequence Information

Coding Sequence: ATGTGTTCAATATTTCGTAATCGCATCAATTATCGGAGCACAGGCACGCGCAGTGGCTCATCCAACGCGGGCAGCTCGTCGTCGGTCGCCGACCCGGCGAGCGAGAGGGACAGCTTGCTAGCCAAGGAGCTCAGCGCGGACAGCAATAACAATGGCAGTGCAGCTGACGAGACGCCAGATGCAGAGATGGAGCGACAGCTCGACGCGGAACAATCGCTGCCCTGCGCCGATCAGCCGGAGAACAGCAACGAGGCGCTCGACTTGTCGGTAATCTCCGGCAGCCGTCTGCCCACAAGCGGGCACGTGGCACTAGAAGCTTTACAACATACCAAAGTGGCGGTGGCCCAGTTTGCGGCCACTGCGCTGGCGGGATCTGTGTCTGATCCGAACGACCTGGCCATGGTCCAGTCGACGATCTTCAATGTCCAGCGCCAGCATCTGATGCAGCTGCAGCTCATCCAGCACCTACAGAGTCAATTGAAGCGAGCGGGTGGCGTGGTGGCTGCGCTGAGCAGGCAAGGCCCGAACTACGCTGAGCCCGAAGACGACGACGAGGAGGAGGACGAGCAGCCGGACCAGACGGATCGCTCCAAGGACCAGCCGAGAGTTAATGGCGACGCAGCAGAGATCGATCACGAAAGGCTGCAGGAGAGTTCAAAGACTGAAGAACAGGAAGCGGAGGCAATATCAAACGAGTGCAATAGAGAAAGCGAACGAGAACGCGAACGGGAACGAGAGCGAAGTGTGGCATTGGCCAGGTCAGAACGGGAGCGTGAGATTGAGGCTGAAGTCGACCAGGAGCTGGAGAGTGAGTATAAGCCTTTAATGTGCGACATCAGCTCCAGCTTGGCATCGAGTATAATCACCAATCACGACCCACCGCCGGCGCCCAATGAACCCAACTGCCTCGAGATGCTGCAGCGGCGCACAGAGGAGGTGCTGGACTCGGCCTCTCAGAGCCTGCATGCGGCCCAGATGCAGGAGGAGTATTCGGAGTATGCCTCCAAGGAGGCGCAGAGCCGCGGGGAGATCTTCAAGCACCGCTGCAAGTACTGCGGCAAGATCTTCGGCAGCTATTCGGCCCTGCAGATACACCTGCGCTCCCACACCGGCGAGCGACCCTTCCATTGCAACGTCTGTGGCAGCAAGTTCACCACCAAAGGTAATCTGAAGGTTCACTATCAGCGCCACACGCAAATCTTTCCTCCCATGCTGCTGCCGCCTGTGCCCAATGGGGCGCAGCCACCGCCGTCAGCGCCCGAGCAGTTTGGCTCCCTCACTCCCATTCGCCTACCCTTTGCCACGCCAGCGCCTCTGGCACCACCTCCAGCGCCCACAGTGGGTCAGCTCGGCAGCGAGCAGTCAGCCTTGGAGCAGCAGCAGCACGAGCTGCAGGCGTTGGCTATGCCGGGACCACAACTACAGCAGGCTGAGGATCTGAGCAAGCCAACCAGGGAGCTGTCGCACTCTCCCATGCCACCCGCGCCGACCCCCAAGTCCCTGCCCGAGCGTAGCAGAAGTCAAAGTGCAGCGGACGCGGCCCCGCCTTGCTTAGCTTTGGCCGAGCACAAGGAGAAGGATAAGTTGAAGGAGAGCCCTAAGTCCACGACGCCGCCTACCACAGCGGCAAGTCGCCGCAATGGGAGCGTGCGCAAGCGGCAGTCCAGCAGTGGGGGCAGTCCGCCAGGGGAGGAGCGAGATCAGTCCGAGCACATGCAGTTGGTGAAGCTCGTGCGTCGCTCCTCGGCGAGCCGCGACGGCGCCGTTGCGCTGCCGGGCGAGTACTCACTCGCTCAGATGGAGCGCATCATAGACAAGTCGTGGGAGGATCTGATCGAGATCGACAAGACATCGGAGACGTCGAAGCTGCAGCAGCTGGTGGACAACATCGAGAACAAGTTGACCGATCCGAATCAGTGCATCTTCTGCCAGAAGGTCATGTCGTGTCGCAGCTCTTTGCAGATGCACATTCGCACCCATACCGGCGAGCGGCCCTTCCGCTGCAAGATCTGTGGACGCGCTTTTGCCACCAAGGGCAACCTGAAGGCGCACATGAGCATTCATAAGATAAAGCCGCCCATGCGCAGCCAGTTCAAGTGCCCCGTGTGCCACCAGAAGTTCTCCAACGGCATCATCCTGCAGCAGCATATTCGCATCCACACCATGGACGATGGAAGCGGCAACCAGGTGCACGACCAGAGCCAGAGTCAAAGTCACGGACAGGGTCTTGGCGCTGGCGAGGCTGAGCGGTTGGGCATTGAGGATCAGAACTCGAACAAGTCAATGGGCACCTCGGACACCCTGGACTTCTCGACGACAATTTCGGATCACTCCGGCCAGAGGTCGGAGTCCTCGCAAGGAGGCGACTTCGACGAGTTCATGACCATGGACAGCACTGACGACTCCCGGGACAACTCGAGCGCAGCCACAGCCACTCTCCTTGACAGAGACAGACGGCCGGGCCACGAAGACGAGCGCTCCAGATCGGATCTGGATGGCGGTGGGCGTGAAAGCAACAGCGGCGAGATGCCCGCAATGGATCTGTCGTCGCCGTCCTCGTCCTCTGCCTCGGCTGCTGCGGCAGCGGCAGCAGCGGCTGCGGCTGCGGCCCGACTCTTCGGTGTCGGCAACAGCACAGTAGCGGCAGCAGCTGGCGGAACTGGAGCTTTACCGATGCTCGGCATGCCCATGCCGCCGAATCTCTTGCTAATGGCAGCGGCGCGCGAGGAGATGCATGCGCTAGGCCAGACGCATGCCAAGTTTCCACTGCTGCCCTTCGGACCGCTCGGATTAATGGGCCTGCAGCCGCCCCCAAATGTGTGCAACTTGTGCTTCAAGATGCTGCCAAGCCTGGCTGCCTTGGAGAGCCATCTACAGAGCGAACATGCCAAAGAAATGACGGCTCCTTCCGCCCGAGTCCATTGCAACGAGCCCGTAACGCCCTATGGAGCAAAGCTCACTCTCAATCCAAATCTATTTGCCAAGAAGCCGAAGCAGCCGCAGGAGCTGGCGCCAGCGGAGCCAGTCACGCCATCGGCGGCATCCATTAAAGAGGAGCCCGACTCCGACCAGCTGCTGGTCGACGAGGGTGGCTGCGAGGGTGGTGCAGCAGCCCCAGCAGCCACCGGCTATCAGCACGACGCAGCCGGCGATGCGGAGCAGTCGCTGATGAAGATGCAGTTGCATGCTCATCGTTTCCCAGCTAGTCCGCTGGACTTCCAGCAGGCCCTGATGTCAGCCGGGCCACCCAGTTCGAGCCTCGATCCGCCGGTGAACAACAAGCACTTCTGCCACGTCTGTCGGCGCAACTTCAGCTCGAGCTCAGCTCTGCAGATCCATATGCGAACTCACACCGGAGACAAGCCCTTCCAGTGCAATGTCTGCCAAAAGGCCTTCACCACCAAGGGCAACCTGAAGGTTCATATGGGCACGCATATGTGGACGAATCCGACTTCTCGTCGCGGCCGCCGTATGTCCTTGGAGCTGCCAATGCGCCCAGGACCTGGGGCGGGCACAGCTCACGGCGCGCCCTCGGCCGAGCAGGAGTTCTTGCAACGCCGACCGGAACTCTTTTTCCCCTATTTGCCTCCCTTCTTCAACGGAATTCCACCTAAGCCCGGCGAATTGAGTCCCGGTGCGTTTGCCAACATACCTCCACCGCACTTTGCCAATGGAGCTAAGTACCCGTATCCGCCTGGCCTGCTGGGCTTTCCAAGCTTCTTGGGCGGAGCTGGTGTCCATCACCAATATCAGCACGGAGTGGAGAGGAGCAGTAGCAAGTCGCCAACATCGGAGCCGGCGCAGAGTCCAGCCTCTCGGGAGGACGACGGAGCTCTAGGCAACAACATTTGGCATCCCCTGAATAGCATCAAGATGGAGAACACTCAAAACGAGAACATGGGCAATCACAGTGAGCTGGAGCAGGAGGACAACGGTGGGGGCGCGGATGCGGATGCTGAGCCCGAGATGGGAGCTGGGGCTGACGATGCGGGATCCCAGGGCTGCGATAAGTAG
Protein Sequence: MCSIFRNRINYRSTGTRSGSSNAGSSSSVADPASERDSLLAKELSADSNNNGSAADETPDAEMERQLDAEQSLPCADQPENSNEALDLSVISGSRLPTSGHVALEALQHTKVAVAQFAATALAGSVSDPNDLAMVQSTIFNVQRQHLMQLQLIQHLQSQLKRAGGVVAALSRQGPNYAEPEDDDEEEDEQPDQTDRSKDQPRVNGDAAEIDHERLQESSKTEEQEAEAISNECNRESERERERERERSVALARSEREREIEAEVDQELESEYKPLMCDISSSLASSIITNHDPPPAPNEPNCLEMLQRRTEEVLDSASQSLHAAQMQEEYSEYASKEAQSRGEIFKHRCKYCGKIFGSYSALQIHLRSHTGERPFHCNVCGSKFTTKGNLKVHYQRHTQIFPPMLLPPVPNGAQPPPSAPEQFGSLTPIRLPFATPAPLAPPPAPTVGQLGSEQSALEQQQHELQALAMPGPQLQQAEDLSKPTRELSHSPMPPAPTPKSLPERSRSQSAADAAPPCLALAEHKEKDKLKESPKSTTPPTTAASRRNGSVRKRQSSSGGSPPGEERDQSEHMQLVKLVRRSSASRDGAVALPGEYSLAQMERIIDKSWEDLIEIDKTSETSKLQQLVDNIENKLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHKIKPPMRSQFKCPVCHQKFSNGIILQQHIRIHTMDDGSGNQVHDQSQSQSHGQGLGAGEAERLGIEDQNSNKSMGTSDTLDFSTTISDHSGQRSESSQGGDFDEFMTMDSTDDSRDNSSAATATLLDRDRRPGHEDERSRSDLDGGGRESNSGEMPAMDLSSPSSSSASAAAAAAAAAAAAARLFGVGNSTVAAAAGGTGALPMLGMPMPPNLLLMAAAREEMHALGQTHAKFPLLPFGPLGLMGLQPPPNVCNLCFKMLPSLAALESHLQSEHAKEMTAPSARVHCNEPVTPYGAKLTLNPNLFAKKPKQPQELAPAEPVTPSAASIKEEPDSDQLLVDEGGCEGGAAAPAATGYQHDAAGDAEQSLMKMQLHAHRFPASPLDFQQALMSAGPPSSSLDPPVNNKHFCHVCRRNFSSSSALQIHMRTHTGDKPFQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLELPMRPGPGAGTAHGAPSAEQEFLQRRPELFFPYLPPFFNGIPPKPGELSPGAFANIPPPHFANGAKYPYPPGLLGFPSFLGGAGVHHQYQHGVERSSSKSPTSEPAQSPASREDDGALGNNIWHPLNSIKMENTQNENMGNHSELEQEDNGGGADADAEPEMGAGADDAGSQGCDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00475377;
90% Identity: iTF_00559655;
80% Identity: -