Basic Information

Insect: Drosophila repleta
Gene Symbol: -
Assembly: GCA_018903745.1
Location: JAEIGN010000497.1:7511584-7516280[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.27 17 5.9 5.3 2 23 336 358 335 358 0.96

2 18 3.5 2.3e+02 2.4 0.0 1 23 365 390 365 390 0.93

3 18 0.0064 0.41 11.0 1.6 2 23 401 422 400 422 0.94

4 18 1.9 1.2e+02 3.2 1.6 2 17 433 448 432 459 0.80

5 18 0.0076 0.49 10.7 1.2 1 23 490 512 490 512 0.95

6 18 0.0016 0.11 12.9 0.2 1 23 520 543 520 543 0.96

7 18 0.00011 0.0072 16.5 0.5 2 23 548 569 547 569 0.97

8 18 1.4 89 3.6 0.1 1 20 577 596 577 597 0.91

9 18 0.00022 0.014 15.6 0.2 1 22 617 638 617 641 0.91

10 18 0.026 1.7 9.1 0.5 1 21 646 666 646 667 0.93

11 18 0.0017 0.11 12.8 0.6 1 23 686 711 686 711 0.97

12 18 0.033 2.1 8.8 1.6 2 23 727 749 726 749 0.93

13 18 0.015 0.99 9.8 0.2 2 23 755 777 754 777 0.92

14 18 0.069 4.4 7.7 0.7 2 23 781 803 780 803 0.96

15 18 6.5e-06 0.00041 20.4 1.2 1 23 809 831 809 831 0.98

16 18 0.007 0.45 10.9 0.8 1 23 835 858 835 858 0.94

17 18 5.6e-06 0.00036 20.6 1.0 1 23 864 887 864 887 0.98

18 18 0.0018 0.12 12.7 0.2 1 23 891 919 891 919 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.27	17	5.9	5.3	2	23	336	358	335	358	0.96
2	18	3.5	2.3e+02	2.4	0.0	1	23	365	390	365	390	0.93
3	18	0.0064	0.41	11.0	1.6	2	23	401	422	400	422	0.94
4	18	1.9	1.2e+02	3.2	1.6	2	17	433	448	432	459	0.80
5	18	0.0076	0.49	10.7	1.2	1	23	490	512	490	512	0.95
6	18	0.0016	0.11	12.9	0.2	1	23	520	543	520	543	0.96
7	18	0.00011	0.0072	16.5	0.5	2	23	548	569	547	569	0.97
8	18	1.4	89	3.6	0.1	1	20	577	596	577	597	0.91
9	18	0.00022	0.014	15.6	0.2	1	22	617	638	617	641	0.91
10	18	0.026	1.7	9.1	0.5	1	21	646	666	646	667	0.93
11	18	0.0017	0.11	12.8	0.6	1	23	686	711	686	711	0.97
12	18	0.033	2.1	8.8	1.6	2	23	727	749	726	749	0.93
13	18	0.015	0.99	9.8	0.2	2	23	755	777	754	777	0.92
14	18	0.069	4.4	7.7	0.7	2	23	781	803	780	803	0.96
15	18	6.5e-06	0.00041	20.4	1.2	1	23	809	831	809	831	0.98
16	18	0.007	0.45	10.9	0.8	1	23	835	858	835	858	0.94
17	18	5.6e-06	0.00036	20.6	1.0	1	23	864	887	864	887	0.98
18	18	0.0018	0.12	12.7	0.2	1	23	891	919	891	919	0.89

Sequence Information

Coding Sequence: ATGTCGGAAAACTCGAAAGTAAGCAACGAAAAGCGGCTTAGCTGCCTGCATTGCAGCGTGCACAATTCAAAACAACAATATCATGAAATATTCGATGAAGTGGGCGTCGAAATCGAATTCGCAGAACTATTAGCCAAGTATTTCCAACTCGTGGTCAAACCCGATGCGCAAAAGTCGCAAGTGCTGTGCCAAGAATGCGTAAATACGCTGATCCGCTTCTTTGACATAGACGAACTGCAACGCGAGCAGGATGCCGCCAATGCAGCCAAAAAGGCGGCCAAGCAGCCGGAGGAACAGCCAAGTGCCGCCAAGAAGCCTGAGACTCCACCGAAAAAGGCGGCGGCAACGCCTGTGCCAAAAGCAAAGAGTGCCACAGTTGCCGCCAAAACTTCGCCAACGCCTGCTAAAGCAGTTAAGCCCGCAACAGTTACAGCTGCATCCAAAGCCGCTCCCGATAGCCTAGCCATACGCATTACTAGAGCCCGCACCGCTACGCCCAAACGTTTGCCCGCCAAGGCCAAGGAGTTGGTTAAAGTAAATGCCAAAGTCAAGGTGAAAAGTCAGGGCTCGGGTGATCAGGAACAGATCAGCGCACTCATACGCGATATTTTGGATGATGAGGAGGCGCCGGCGGATGATAAATTTGCCGAGGCAGCTGCGACCGTGCGGCAGCTGGAAAAGCAAACAAACAAAAAGCAGCAGGAAGAAGCGGATCAGCAAGTGGAAGAGGATAACAATGATGAGCTAGAGTTTCTGCTACAGCAAGAAGACAACTCCTCCGACGTGGATGTGCGTCACTTCAAAGTGGAGCGCAAGGTCAAGCGCGCCGCTACGCGATCCCAATCCCAGTCGCAGACTGAAACCCAAAGCGAGGATGAATCGTTTAAAGTGGAGCCTTTTAATTTTGTCCTAATCAAAGAATCTGACAACATTGGCGATCTGCATGAATATCTGTCGACTGTGGTCAAGACCTGCTTTGAGACCCTGCAATTCGACTGGGCCACAGTCTGTCGTCACTGCTCGCTGAAGTGCAGCAAATTTGATACGCTGCTCAGTCACATGCAGAAAGTGCATCAGCTGGCGGACGAGCGCTACAGCTGTCCCATTGAAGGCTGCACGGCGGAGCTGAAAGGCCGAAAATATCTGGCCATGCATCTGGTGGTGCTGCATGCGCCTGTGGCAGAAATACCCATTTATGGCAAGTGTCCCGAGTGCAACATGACCTTCTCCAACATATTGCAATATAATAAACACTCCTGCGCGCACGTCATTAAGAAGCGTTGCGGCATACGCTTATACTGCGAGATGTGCGGCTTGGAGTTTCCCTCCTGGAAGCGCTTCAACTTCCACAATCAATTCCATTTGGAGAACCACAGGCCGCGCGCTTGTTTCGTGTGCAATTTTGCGGACAATAATATTGATGAGCTCTTCCATCATTTGCACTATGCACACGAACCCGAAGGCACGCACTTCTGTGATATCTGTGATCGCAACTTTCGCGATGCTGCTGTGTTTATGGAGCACAACAAATCCCATTCGAATGTCACCAGCACCACCTACAGCTGCTCGGAATGCAGCGCCAACTTTGAGACTCGGGGACGGCTCAATGGGCATATGCGCGCCGTTCATGGCAGTGTCATTAGCTGCGAGCTGTGCAGTCGCGAGTTTGCCACAGAGTCGACCTACAATCTGCACATGAAGACGCATCTGATCATTGAGCGCGAGATGCACGTGTGCAGCGGCTGCGGCTTGCTCAGCGAGAGCAACGAGAAGCTGCTGACTCACGTTGAGGCGGAAGACTCAGCTTGCTTTGGCATGGAGACCTATGCGGAACTGCTACGCAACGCTTATGTGTGTGAATATTGCTCGGGAAATTTTAAGCAGAAGAGCGATTTGATTGCGCATCGCGAGTCGGGCGTGCACAAGGATGGCAACTTCATATGCCAGCCGTGCGGCAAGGAATTTGCCGACATGAAACTCTATCGCCATCATCTGCGCAACTTTCAGCAGCAGCGATCGGATGTAGCGCATCGCAGGCTAGAGATATGTCTGTACTATATGTGTGACTATGAGGATTGCACTGAATCCTATATTAACTGGAACTCGCTGTACACGCACAAGCGACGCCTGCACGATGCCGCCGCCAAGCAGGGGTCGCAAGCTAAAGAAAACGAATGGATCTGCCAGTTCTGCCAGAAAGAATGCAGATCCAAAATGTCGCTATCGGTGCATGTGGCGCGCAGTCACAATAATAATAATGTCGTTTGCCCGCTGTGCAAGTCCTCTTACAAGGATACAGATGCCTTGGCCAAACATCACGCCTACTGGCATGAGCCTATGGAGTGCCGTTTGTGCTCGAAACTGGTTAAAAATCGTCGTAATTATGATACGCACATGAATGTGGTGCACTCGAATAACAAACGCTACTCGTGCAGCGTCTGCCCCAAGGGCTTCTATCACAAAAGCGAAATGGAGGCGCATCAGCGGCTGCATAGCCAATCGTATAGCTGCGAGCAGTGCAGCTTCATCACACGGAACAAGAAGTCGCTGACGGTGCATGTGCAGGGCCAGCACTTCAAGCGCTTCGCCTTCCAGTGCAAGGAGTGTGACAAGCGTTTCGGACGTCGCCAGGGACTCTCCAATCACATACAGCGCGTGCATGGCTCCAGGTATACGTGTCGCGACCTGTACGACGGCGGCTGCAGCAAATCCTTCGGGACGACGGCGCAGCTTAATGTGCATGTGCGCAAGGCGCACGACCCCAGAATATATTTGGATGACGATGCGGCCAAGGAACTGGATGAGGAGGAGGAAGAAGAGGAGGGCCTGGAGCGGGAGCAGGAGCCGGAACAGGAGGAGGAGGAGGAGGAGGAGAAGCAAGTGAAGAGCGAAGCGCCGTCGACATCGAAGAAGCGCCGCAAGCGCCTCAGCGCGAACACCAAAATCGAGGATCAGGAGACGGCGTCAGAGGAAGCGACGCGACCGAACAAGAAGCAAAAGCCCAATTAG
Protein Sequence: MSENSKVSNEKRLSCLHCSVHNSKQQYHEIFDEVGVEIEFAELLAKYFQLVVKPDAQKSQVLCQECVNTLIRFFDIDELQREQDAANAAKKAAKQPEEQPSAAKKPETPPKKAAATPVPKAKSATVAAKTSPTPAKAVKPATVTAASKAAPDSLAIRITRARTATPKRLPAKAKELVKVNAKVKVKSQGSGDQEQISALIRDILDDEEAPADDKFAEAAATVRQLEKQTNKKQQEEADQQVEEDNNDELEFLLQQEDNSSDVDVRHFKVERKVKRAATRSQSQSQTETQSEDESFKVEPFNFVLIKESDNIGDLHEYLSTVVKTCFETLQFDWATVCRHCSLKCSKFDTLLSHMQKVHQLADERYSCPIEGCTAELKGRKYLAMHLVVLHAPVAEIPIYGKCPECNMTFSNILQYNKHSCAHVIKKRCGIRLYCEMCGLEFPSWKRFNFHNQFHLENHRPRACFVCNFADNNIDELFHHLHYAHEPEGTHFCDICDRNFRDAAVFMEHNKSHSNVTSTTYSCSECSANFETRGRLNGHMRAVHGSVISCELCSREFATESTYNLHMKTHLIIEREMHVCSGCGLLSESNEKLLTHVEAEDSACFGMETYAELLRNAYVCEYCSGNFKQKSDLIAHRESGVHKDGNFICQPCGKEFADMKLYRHHLRNFQQQRSDVAHRRLEICLYYMCDYEDCTESYINWNSLYTHKRRLHDAAAKQGSQAKENEWICQFCQKECRSKMSLSVHVARSHNNNNVVCPLCKSSYKDTDALAKHHAYWHEPMECRLCSKLVKNRRNYDTHMNVVHSNNKRYSCSVCPKGFYHKSEMEAHQRLHSQSYSCEQCSFITRNKKSLTVHVQGQHFKRFAFQCKECDKRFGRRQGLSNHIQRVHGSRYTCRDLYDGGCSKSFGTTAQLNVHVRKAHDPRIYLDDDAAKELDEEEEEEEGLEREQEPEQEEEEEEEKQVKSEAPSTSKKRRKRLSANTKIEDQETASEEATRPNKKQKPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512900;
90% Identity: iTF_00568422;
80% Identity: -