Drep009866.1
Basic Information
- Insect
- Drosophila repleta
- Gene Symbol
- hang
- Assembly
- GCA_018903745.1
- Location
- JAEIGN010000750.1:4087925-4092621[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 6.1e-05 0.0039 17.4 0.2 2 23 22 43 21 43 0.97 2 11 0.00011 0.0074 16.5 2.9 2 23 138 160 137 160 0.97 3 11 0.009 0.58 10.5 0.2 2 23 169 191 168 191 0.95 4 11 0.00048 0.031 14.5 0.1 1 23 204 227 204 227 0.97 5 11 5e-05 0.0032 17.6 1.1 1 23 271 293 271 293 0.99 6 11 0.00077 0.05 13.9 0.9 1 23 301 324 301 324 0.96 7 11 1.1e-05 0.00068 19.7 0.4 3 23 387 407 386 407 0.98 8 11 0.002 0.13 12.6 0.1 1 23 442 464 442 464 0.97 9 11 0.00024 0.015 15.5 0.6 2 23 549 571 548 571 0.93 10 11 2.7 1.7e+02 2.7 0.1 2 20 591 610 590 612 0.90 11 11 0.0026 0.17 12.2 0.3 3 23 627 647 627 647 0.98
Sequence Information
- Coding Sequence
- ATGCGATTGGACGACAGCAGCAACAACAGCAGCATCAACATGGGCATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTCAGCAACAACATTGGCTTGTCGAACCACATGCGCTCGCACTACACCGCCTCGACGGCAACAAATGCCGCGCTGGCGGCTGCCAATCGCATGACGCCCAAGTCCTTAACAATTACTGCAACGCCGCCATTGGAGGCGACTGCAGCTGCGTCTACGGCGACGCCCGTCACAGGCACAACAGCAGCGGCGGCTGGGGCAGCAGCTGGAGCCACGCCCACAGCCGCTGGCGGCTTGCCGCCCGCGATGGTGCACCAGACGCCACAGGAGCAGGCCGTGTTCCGTCGCAGCCTGGATCAGGCGGCCGATCGGCGCTTCCGGCGCATGCGCTGCCGCATCTGCCAGCGTCGCTTCAGCTCGAAGAAGTCGTATCGCTACCACATGCTCACCGACCACCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTCTGCAATGCAGAGTTCGCCTACGAGAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCGATCAAGGACGAAATGATCATCAAACAGTTCGAGTGCGATATTTGCTCAATTGTCTACAGCTCGGAGCTGGAGCTGCAGCAGCACAAGCGCAGCGTCCACAAAGCCCTCGATGGCGGCTCGAAATCAGCAACCAAATCATCTACAGCTACCTCAGCCTCAGCCTCTGCTGACCAGCAGCTGACCACCGACGCTACGGGCGCACCCGCGGCCGTCCTGCCGCTCTACTGGTACCAGTGCAAGTACTGCCCCTCCAATTTCAATACCAACAAGAAGCTGGCCATCCATATCAACTCGCACGACGAGTTCGACTCGAACGACTATTCGTGCAAGGACTGCGGCAATGTCTACAGCGGACGCAAGAGCCTCTGGGTGCATCGCTATAAGAAGCATCCGCAGCATAAGACGGGCGACGACGACGACGAGGAGGACGATGAACGGCTAATGATGCTGGACGATAATGCCACTGGCAGCGACAGCAACGGCGGCACTGCGGCGCTCAGTGCGCCGTCGGCCAGCAACAATACGAATACGACGATAAGCGCTAGCACACTGAAGATACGCATCCCGGAGGTGGCGTGCACCATTTGCGGGGCCCGCTTCACCGACCAGGAGATGTTCACGAAGCACATACAGAAGCACGAGCAGGATCTGTATGTGGACAACCCGTTGGCGGCCATGTTCGACGACGGTCCCGCCGATGCGGGCCAGTTTCAGGTGGAGCGTCAGAACGAGAATGGGGAATACGCCTGCGACTTATGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCTCATCATCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCGCAAACGCGAACTGAAGTGTGAATATTGCGCCTCCACGTTCATCAGCAACAACAACCTGCGTCGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCAGAGCCGCCGGTCATCGAGGTGGACAAGCCGCTGACGTGTCGTCGCTGCGGCGATAAGCGGTTCGAGACGAAAGAGCTGTGGATCGAGCATAAGCTAGCGGACGCCAAGGTGGTGCGTCCCTTCTGTCCATTCCAGTGGGGGTGTGATCTGTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAAGAGGATGTGATAGTGCCGGTGGCGGCGGTGGCCAAGGCATCCCCAGCTGCCGGGCTGAACAACAAGAATGCAACGGCCAAAGCAACAGATGGAGCAGCAGCAACAACAACAGCAGGAATAATAACAACAACGGGGGCCAAGGGCGCCTTAATTGGAGCGGCGACGGCAGCAGTGAGCGGCGGCAGAGTGAATAAGAGTAAGCAGCTGGAGGAGCAGCTGGCAATGAAGCTGGCAGCCAACAACACTAAGCAGCAGGGCACCAGGCGCCTCAACTTTGACTACTCGCGGGCCAAGCTGAACGGCACTGGCAAGCAGACTCTGGCCAAGCCGAAGCAGCAGCAGCAGCTGGTCATGCACAGCTCGGAGGAATACGATGATGGTGCCGAAGAGGAGGACGAGGAGGATGATGATGACGATGACGACGACGATGTGGAAGAGGATATGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCAACAACAATCGTCGTCGCGACGGCGCTGTGATGGTCAGCGGCATCAGCATTGGCGACGGAGCGCCCGATGCTGATGGTGATGGTGATGCGGATGGCGATGGTGATGGTGATGGCGACGGCGATGCTGATGGTGATGTGGACGCTGAGGCTACATCATCATCGGAGAGCGAGAAGTGA
- Protein Sequence
- MRLDDSSNNSSINMGIANQQKECLICNAVFSNNIGLSNHMRSHYTASTATNAALAAANRMTPKSLTITATPPLEATAAASTATPVTGTTAAAAGAAAGATPTAAGGLPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDICSIVYSSELELQQHKRSVHKALDGGSKSATKSSTATSASASADQQLTTDATGAPAAVLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQHKTGDDDDEEDDERLMMLDDNATGSDSNGGTAALSAPSASNNTNTTISASTLKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNLIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDKPLTCRRCGDKRFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVAAVAKASPAAGLNNKNATAKATDGAAATTTAGIITTTGAKGALIGAATAAVSGGRVNKSKQLEEQLAMKLAANNTKQQGTRRLNFDYSRAKLNGTGKQTLAKPKQQQQLVMHSSEEYDDGAEEEDEEDDDDDDDDDVEEDMXXXXXXXXXXXXXXXXXXXXXXNNNRRRDGAVMVSGISIGDGAPDADGDGDADGDGDGDGDGDADGDVDAEATSSSESEK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -