Basic Information

Insect: Drosophila rellima
Gene Symbol: BCL11A
Assembly: GCA_035043635.1
Location: JAWNMV010000134.1:6160894-6179104[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.026 1.8 9.2 2.4 1 23 283 306 283 306 0.95

2 6 2.6e-06 0.00018 21.8 1.0 1 23 756 778 756 778 0.97

3 6 0.012 0.85 10.3 4.7 1 23 784 806 784 806 0.99

4 6 1.1e-06 7.9e-05 22.9 3.2 2 23 1083 1104 1082 1104 0.97

5 6 1.5e-05 0.001 19.4 3.3 1 23 1110 1132 1110 1132 0.99

6 6 2.7e-05 0.0019 18.6 0.4 1 22 1140 1161 1140 1161 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.026	1.8	9.2	2.4	1	23	283	306	283	306	0.95
2	6	2.6e-06	0.00018	21.8	1.0	1	23	756	778	756	778	0.97
3	6	0.012	0.85	10.3	4.7	1	23	784	806	784	806	0.99
4	6	1.1e-06	7.9e-05	22.9	3.2	2	23	1083	1104	1082	1104	0.97
5	6	1.5e-05	0.001	19.4	3.3	1	23	1110	1132	1110	1132	0.99
6	6	2.7e-05	0.0019	18.6	0.4	1	22	1140	1161	1140	1161	0.97

Sequence Information

Coding Sequence: ATGTACAACAAAATGCTGTCGATCAGTGAGGATCATGGATTCCGTTCGCTGAGCCATTCCGACTCCACAGAGAACGATGCCGTCGCCGCACAGGACATCCTCACGTGTGGCGCATGCCAAAGGACCTTCGCGCTGTCGGACATCGTCCGGTTCATCCAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTACGGCCAATGCACGACGCAGGCGCCGAGCATGGATCGGGATGCCGACGAGGGTCGCCCATTGAGTTTGGTCAATCGCCGTCCCTCGATTTCGGCGCCCATCACAGCGGGCCGCAAATCGGCGCCGGTTGCCGTCGGTGGTGCCGGCAGTGGGGCAGCCAGTGCGGTGGCAAGTGCcgcggcagcagcggctgcGGCGGCTGCAACGGccgcggcagcggcagctgcggTCGCGAACAGTGCGTCAAGTGGCTCGCGGATACACACACCACCGCCAAGTCCGGCGGATTTGCTAGCCGACGGCGCCAGCAGCACGCCCAAAAGATTAGTAGATGAGAACGACAATACGACGCCGAAGGCTGACAACGATGCTCTGACCTCGGCCACGCCCCTGGAGGCAACTAGCAGTCCACGTGCCCCATCGCAGTCGGAGCTGCCACAGATCGATGACTGTGACctggacgacgacgacaagcCAAAGGTCAAACAGGAGCCCACGTATGCCgacgatgatgaagatgagcaacagcaactgccacagtcacagacacaacaacaacaacaaaatgtcgaCCTGGACAGCGAaCCGCTGGCCAAAAGACCCAAAATGGAGCTGGTTGATGCCGAGGCCAACACGGTGCATACAGAACCTAGTAATTACACGTGCTCGACATGTAAGACGCGTTACACGTCCGCGTGGCGCCTCATTCAGCACGTGCAACATTCGCACGGCGTCAAGATTTACGTGGAGGCGCAAGGTGGCGCCACCTTGACAGTTGCCACGCCCGCCGCCCTCAATGCGGCggccacagcagcagcggccaacgccaacgccagcgTCAACGccaacgtcagcagcagcgtcagccCAAATCGCAGTTTAAGCccctcagcagcagcagcagctgcagcggcggcggcagcagcagcggttgGTGTCCCGTTGCCGTTGCACGCGCTCATGGCGCAGGCAGTGGCctcgcagtcgcagtctccGGCAGCcaagcgcagcagcagcagcagcaacaacagcagcagcaacaataattcactggcagctgcaacagttgcaaatACGAGCAGCGGAAGCAGCAATGCCAGCAGCGGAAATTCGCCAACACAGCatttgctgcagcagcaacagcgcgctcaacaacaacaacagcagcagcagcagcagcaacagcagcaacaacagcagcaacagcaacaacagcaacaaaacatgGCATCGGCAATGGCAGCTGGAATGCGTCATCATCCATTGCTGGCACCGCCGGAGGCAATGCACGCGAATCCGTTTCAATTGCTGCGAATGCCGCTGCCGGCAGCATTGACCCAGAGCAATGTAGTTCCTAGCGTGTCGCCACTCTTCGGGCGACCCTCGCCCGCCGACCACTATCGCATGGAGCAGTTGGTGAGCGAACAGTTTCGTCATCACGGCTTCAATTTAGCCGccgcggcagctgctgctcaggCGCAGTTCAACGCGAgcaatcaacagcagcagcagcaacagcagcaacaacagcagcagcagcaaccggTTGTTGGTACAGGTGCTGTCGTCAATGTTCCTAATGCCGTCGAGCAGCGTCCGCCGtcgagcaacagcagccaacgTGGCTCTGTGCCGCCCGCCTCATTGCCGCCGCCATCGCTCAgctcacagcagcaacagcagcagcagcaacaacagcagcagcagcagcagcaacaacaacagcagcaaccaattgctgctgctgtgagtCCTGCGTCGGTGAGTTTGGAGCCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCACGACAGAAGCAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCGCCGTGACGCCCACGCCGCGTCCGCACTCCCTCACGCCGCCCGAGAAGTGTCCCACCTCCGAGAACGGCGCTGGCAACTTGACCCTACCGACCACGCCCCGTTCCGCGAGCACTCCGCCCACGAAGGCAACGGACGCCACGGTAGTGCTGGAGGCGAACTGCTTTGCCTGCGGCTATTGCGACAAGAAGTTCAGGTTCGAAAACAATCTGATCATCCATCAGCGGACGCACACTGGGGAGAAGCCCTACAAGTGCACCGCCTGTGACTTTGAGTGCTCGCACATCCAGAAGCTGATGAAGCACATGCGCGTCCATCGCAGTCCCGCCGAGGGACAAGatggcggcagcagcaacggcggcGACAACAATCAGGACGGTCACGACGGCGGCAGCAATGCCGATTCGTTGGAGACCAACGAGGCTGATAACGACAACGATGATGATCCCAATCCCGATGAGTCCGATGAGGAGCTTAATGATGAGGATGCCGACGCGGATGCCGAAGGCGAGGgcgaagatgatgatgaagatgagcTGGACGATTGCGAAGATGTTGACTACGAGGCCGAAGATCTGAGCGTCAACAATCGCATCGATGGCAAGAGCCAGAGTCCCAAGACGACCAGCTCGGGTGCCACCTCCCTGGTGGGCGAGCTGATGGACAAGTTCGGACTGTCGAACATTGCCCAATACTCCGAGGCGTACAAGCAGGCGCTGCAGGAGTCGGGGCGCAAGGAGGCGGCCGCTGTggccgccgcagcagcagttgctgccgccgtcgacaacaacaatcgcgGCTCGGCGGCAGCTGGTGGTGCGCCACCGCAACCACTGACCGATAAGCTGAATGGCTTGCCGGTGGCAGCGCTGAGATTACGCGATGAGTTCGCCAAGAACTGCAACATGTTCCAGCCGCAGCCGCAGGATGCGCCCGCCCAGGTGCCGCTCTTCAATCCGTTCCCCAATCCCTTCGAGCTGTCAAAGCGCATGAAAATGGACGGCGGCGACTGGTGGGGCATGTCCGCGCTGCACCGCAACGAGGCACTCTTCGAGAACCTCAAGTTGAAACCGCTCGGCTTGGGCGGCGCCAACTCGCTGCTCCAGGGACCGCTGCTCAAGAAGGAGAGCCGACAGCGCAACGACACCTGCGAGTTCTGCGGCAAGGTCTTCAAGAACTGCTCCAATCTAACCGTGCACCGTCGCAGCCACACCGGCGAGAAGCCCTACAAGTGCGAGCTCTGCTCGTACGCGTGCGCCCAGAGCTCTAAGCTTACGCGCCACATGAAGACGCACGGACGGACCGGCAAGGACGTGTATCGCTGTCGCTTCTGCGACATGCCCTTCAGTGTCCCCTCCACGCTCGAGAAGCACATGCGCAAGTGCGTCGTCAACCAGGGCAaagccgccgctgctgctgccaacgcAGCTAACGCGGTTGCTGCCGCGCAAGCCGCAGCTGCCGCACAGCAACTGCAAGCGGCCGCCcaggcacagcagcagcaacaccagcaccagcaccagcaacatcagcagcagcaacaacaacaacagttatcCTCGCAGTCACAGCTGTCGCCCGCTTGCCCCATGGGCGTGTCCGTCGGCTTCCCGCCCCAATTTGGACACAATCTGTCGCTGCCGGGCAGCGTGAGCGGGGACAATGATTCGAACGCGTCTTCCAGCCTGCCAGCGCACTCCATATCCCTGAAAGAGGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTENDAVAAQDILTCGACQRTFALSDIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITAGRKSAPVAVGGAGSGAASAVASAAAAAAAAAATAAAAAAAVANSASSGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADNDALTSATPLEATSSPRAPSQSELPQIDDCDLDDDDKPKVKQEPTYADDDEDEQQQLPQSQTQQQQQNVDLDSEPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVEAQGGATLTVATPAALNAAATAAAANANASVNANVSSSVSPNRSLSPSAAAAAAAAAAAAAVGVPLPLHALMAQAVASQSQSPAAKRSSSSSNNSSSNNNSLAAATVANTSSGSSNASSGNSPTQHLLQQQQRAQQQQQQQQQQQQQQQQQQQQQQQQNMASAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPAALTQSNVVPSVSPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNASNQQQQQQQQQQQQQQQPVVGTGAVVNVPNAVEQRPPSSNSSQRGSVPPASLPPPSLSSQQQQQQQQQQQQQQQQQQQQQPIAAAVSPASVSLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSAVTPTPRPHSLTPPEKCPTSENGAGNLTLPTTPRSASTPPTKATDATVVLEANCFACGYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAEGQDGGSSNGGDNNQDGHDGGSNADSLETNEADNDNDDDPNPDESDEELNDEDADADAEGEGEDDDEDELDDCEDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAVAAAVDNNNRGSAAAGGAPPQPLTDKLNGLPVAALRLRDEFAKNCNMFQPQPQDAPAQVPLFNPFPNPFELSKRMKMDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQHQHQHQQHQQQQQQQQLSSQSQLSPACPMGVSVGFPPQFGHNLSLPGSVSGDNDSNASSSLPAHSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519433;
90% Identity: iTF_00602088;
80% Identity: -