Basic Information

Insect: Drosophila rellima
Gene Symbol: Znf574
Assembly: GCA_035043635.1
Location: JAWNMV010000143.1:3380525-3382751[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.067 4.7 7.9 0.8 2 23 334 356 333 356 0.96

2 10 1.5 1e+02 3.7 0.3 6 23 366 383 366 383 0.97

3 10 1.4e-05 0.001 19.5 0.9 1 23 389 411 389 411 0.98

4 10 0.00032 0.022 15.2 1.3 1 23 422 445 422 445 0.90

5 10 2.2e-05 0.0015 18.9 0.9 1 23 453 476 453 476 0.97

6 10 1.9e-05 0.0013 19.1 1.1 3 23 484 505 482 505 0.92

7 10 0.0078 0.54 10.9 0.3 2 23 517 539 516 539 0.97

8 10 9e-05 0.0063 16.9 3.1 1 23 546 569 546 569 0.93

9 10 2.4e-06 0.00017 21.9 1.2 1 23 575 597 575 597 0.98

10 10 5.9e-05 0.0041 17.5 1.4 1 23 603 626 603 626 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.067	4.7	7.9	0.8	2	23	334	356	333	356	0.96
2	10	1.5	1e+02	3.7	0.3	6	23	366	383	366	383	0.97
3	10	1.4e-05	0.001	19.5	0.9	1	23	389	411	389	411	0.98
4	10	0.00032	0.022	15.2	1.3	1	23	422	445	422	445	0.90
5	10	2.2e-05	0.0015	18.9	0.9	1	23	453	476	453	476	0.97
6	10	1.9e-05	0.0013	19.1	1.1	3	23	484	505	482	505	0.92
7	10	0.0078	0.54	10.9	0.3	2	23	517	539	516	539	0.97
8	10	9e-05	0.0063	16.9	3.1	1	23	546	569	546	569	0.93
9	10	2.4e-06	0.00017	21.9	1.2	1	23	575	597	575	597	0.98
10	10	5.9e-05	0.0041	17.5	1.4	1	23	603	626	603	626	0.97

Sequence Information

Coding Sequence: ATGGCCGCCTGTGTGCTTTGTCTTGGATGCTGCAAAATCGGCGAGTCGTATAAGATATTCTCCGAGGCAGGTTTGCGGCTGAGCATTTgccaaacaataaacaaacatttttggttGGAGTTAAATGCGCTGTCCGGTGAAAATGAGGAAGTTTGCCATCAGTGCTGGGAGTGTGTTAACaactttaatgaattttacCAAGGCGTCTACAACACGCACCAGGAACGACGCGAAGTCAAGAATGTGCCCATCGATTTCTGTGCTGAAACGGAAGCAACTAATCCGCTTGCCCTTGGAGCGGAATTGGATGCACTGGCAGAGGATTTCTTTGCATCTGGTAACGTCAAAGTGGAGGTGAACGAACTGGAACCACTGACCAAGCTGGAAGTTCTCGAGCAGCCAGTGATTGAAGAAACAAAAGCTACAAAACGCGCCAGTGCCGATAATCCAACAGGTGCAAAGCGTCGCATCAAAAAGGAGAAACTGACAATCCTTAGTGACTCTGATGGTGATGTACCACTCGCAGAGTTTCTCGACCTGAAAAAGGCTGGGAAACCAAAGGCATCCGGCGATGACCCAACGGCTGCTAAGGGAAGACCATTGCGTAGGAGCTCTCGACGTGGCTGCAAAGCGAAAACATCGCCCGAATCATCTCCAGCTAATTTAAAACAGGAGTGCGTGTCTGAAGAAGAGCTTGAtaatgacaacgacaatgacaatgacgtGGATTTCGCAGCTGCCGAGGCGGTGCTAGGCACCGATGACAGTGAAAGTTCCAGTGAGAGCAGCGACGGCGATTCTGGGGACAGTTTGCCCGAAATCGAGCCAGAGGAGCGCTACGCAGAGATTCCCAAGCGCGTTGTTGTCAAGCCCAAGAAATACCGCAAACGTCCCAAGCCATTGGTTCCACCCGTGCGCATGAGTCGTGAAGAGATTGAAAAGCGAAAAGCTCAACAGATCGAATACGATGAGATTATATTCGACTTCTTTAAGAAACTGCCATGTCACATATGCAACCTGCTGGTGCAGAACTTTGGAGACATGCGACGCCATCTACGCATGACCCACAACATTGAAAGTGGATTTATCGCCTGCTGTGGTCGCAAATTTCACTTACGCAAAGGACTCGCTGAACATGTGCTTGTCCATAAGAATCCCGAACACTTTATGTGCACCCAATGCGGGCGTGTGTTCCAGGACTCTAAAACTCTTGAGACGCACGAGCAGACGCACGCAAATCCTCAGTCACAGGAAAAACCGACTTACCAGTGCGAAAAGTGTCCCAAGAGTTTTACCACAAAAGCAGCTCGCGAGTATCACAATTTATCCAAGCATGTGCCAAAGTCGGACTTCAAGTACACCTGTCCCGAGTGCAACAAGAAATTGCCCACGGCGCGTAAACTGAAGCAGCATCTGCGCTACATGCACGATCCCGAGAGTGCCATCATCTGCGACAAGTGCGGAAAAACGCTGCGCACTCAGGCGAATCTCAAGAAGCACCACGAGCTGGAACATTCCGATGCGCCACGTCCCAAGCCCGATCCAGTGCAGTGCGAGATATGCGGCACATGGCTGCGTCACGTGTCTGGCCTCAAGCAGCACATGAGCACCGTGCACGAGCCACCCGGAACCGAGCATCGTTGTCCCATCTGCGACAAGAAGTCGACAAATGCGCGGGCTCTAAAGCGACACATTTACCATAACCATCAGTGCGAGCGAAAGTTCCGTTGCACCATGTGCGAGAAGGCCTTCAAGAGGCCACAGGATTTAAGAGAGCACACATCCACGCACACGGGCGAGGTGCTCTACACCTGTCCCAACTGTCCGCAGACGTTCTTTTCCAATGCCAACATGTACAAGCATCGGCAGCGATTGCATCGCGCTGAATGGGAGGCGGATCGCAAGAAACCTCTGCCGCCCAACATAATGAAACAGGCGTCATCGACCATCAAGAAACGACAGGTCATCACTATCACCACTGGCCTGGGAGTCTTTACACAATCCGTTGACCTGGCCGAGGGTGTCCACAAACAGGAACCTCAGCTGCAATAG
Protein Sequence: MAACVLCLGCCKIGESYKIFSEAGLRLSICQTINKHFWLELNALSGENEEVCHQCWECVNNFNEFYQGVYNTHQERREVKNVPIDFCAETEATNPLALGAELDALAEDFFASGNVKVEVNELEPLTKLEVLEQPVIEETKATKRASADNPTGAKRRIKKEKLTILSDSDGDVPLAEFLDLKKAGKPKASGDDPTAAKGRPLRRSSRRGCKAKTSPESSPANLKQECVSEEELDNDNDNDNDVDFAAAEAVLGTDDSESSSESSDGDSGDSLPEIEPEERYAEIPKRVVVKPKKYRKRPKPLVPPVRMSREEIEKRKAQQIEYDEIIFDFFKKLPCHICNLLVQNFGDMRRHLRMTHNIESGFIACCGRKFHLRKGLAEHVLVHKNPEHFMCTQCGRVFQDSKTLETHEQTHANPQSQEKPTYQCEKCPKSFTTKAAREYHNLSKHVPKSDFKYTCPECNKKLPTARKLKQHLRYMHDPESAIICDKCGKTLRTQANLKKHHELEHSDAPRPKPDPVQCEICGTWLRHVSGLKQHMSTVHEPPGTEHRCPICDKKSTNARALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMKQASSTIKKRQVITITTGLGVFTQSVDLAEGVHKQEPQLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610837;
90% Identity: iTF_00585399;
80% Identity: -