Drel008303.1
Basic Information
- Insect
- Drosophila rellima
- Gene Symbol
- -
- Assembly
- GCA_035043635.1
- Location
- JAWNMV010000529.1:2692216-2694411[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.019 1.3 9.6 6.5 2 23 213 234 212 234 0.97 2 12 0.0004 0.028 14.9 4.1 1 23 240 265 240 265 0.95 3 12 7.9e-05 0.0055 17.1 0.7 1 23 272 297 272 297 0.95 4 12 0.00015 0.01 16.3 2.2 1 23 305 327 305 327 0.96 5 12 0.00028 0.02 15.4 0.8 3 23 336 356 334 356 0.98 6 12 0.00067 0.047 14.2 0.2 1 23 362 384 362 384 0.98 7 12 0.0064 0.44 11.1 2.9 1 23 390 413 390 413 0.98 8 12 0.00024 0.017 15.6 2.3 1 23 419 441 419 441 0.97 9 12 0.00016 0.011 16.2 1.4 1 23 447 469 447 469 0.98 10 12 1.4e-05 0.00096 19.5 0.3 1 23 552 575 552 575 0.96 11 12 0.0013 0.088 13.3 7.1 1 23 581 603 581 603 0.96 12 12 2.9e-05 0.002 18.5 2.5 1 23 609 631 609 631 0.98
Sequence Information
- Coding Sequence
- ATGAATGAGGAGACTCCACCCTCAATTCATACGATATGTCGCACTTGTTTGTCGAACTTGCAGCAAGATGAAGCCTTCGACCTGTTTGCTGTTCCGGACCTGGCCaagaaattgtgtgtgtgcacttcGCTCTCGGTGGAGCACCAAGATGGATTCCCGAGAAACCTCTGCACCACCTGCCACAGTCGCCTCAATGATTTGCATGACTTTCAAAAGCAGTGTGTGGACTCTGTGCAAAAGTTCAAGGAGTTGGTGTCCCGAAACTGCTTCATAATCCAAACTGTTCCCGAGGACGACGTTGTCCATGAAAGGGAACACATAAGCTTTGACCCTCTTTTGAATACAAAACTGGAAATCGATAACGAGGAGgatgtttttaaaatgattgaagATGTTGATAAGGAATCCGAGGATGTAGATCATTTGGAGGATGCATTTAATGACAGCGGAAGCGACTATCACAATGAGGATGAGAACTTCCAAGCGGATAGCAGCGATTCCGATGATGAGATGCCGCTGTCACGCCTGCGAGGTAATTCCAGAGCCAAGTCCAAAAAGGATGATAAGAATAAGCCTAAAGAAAAACCGAAACGTAGGCGAATTCCGGCAGCTGAGCGGCATTTGCATCGCACCGTGGAGTGTCACATTTGTAATCAGAAATTTATTAAGACATCTTGTTATGAGGAGCATATGAAACACCACAATGATCAATTACCTTTTCAGTGCACAGTGGAGAATTGTAAGAAGGGCTTCACGACATCCACAGGACTCAAACATCATATGGAGCACACGCACACGGAACTATGCGATCTTCATCCGTGTACAGTCGAAGGATGCAACGAATCCTTTGCTCAGACCCGAATGCTCACCCAACATATGAGGAAGGTGCATAATATTGCCAAGCCCATAATACATCCATGTCCGGAATGCGACAAAGTTTTCCGCTGTCCAATGGCGCTGAAGAAACACATGTATAATCACACCGGCGAGGAGTTGCCCTTTGGTTGTAACATCTGCCAGAAGCGCTACCGAGTGAACACCGAACTTCGGGATCACCTTTTGCGGCATGCCGGAATCAAGAACTTCGTCTGTCCTTATTGTGGTGTGGGCAAAACCACTAAGCAGGAGTTGGATAAGCATATGCTGACTCACACAAAGGAGAAGAAGTTCAAGTGTGATCAGTGCGATCATAGCTCCTCGAGTAAGCAACGCATGTCCAAGCACATCAAGGTCGTTCACTTGAAAATCAAGGACTTCGTTTGTCAGTATTGCCCGAAATCCTTTAGCACTGCTTATGACTGCAAGATCCACGAGAGATTGCACACTCGGAATGATTGCTTCGAGTGTTCAATTTGTGGaagaaattttctttttgagaGTAGATTAACGAAGCATTTAAGGACTCACGAGAAGCGCAAAAATAAATCTGCTACGAGCTCCAAAAAGACGGAAACTGACGGGGATGAACAGACGGAGTCAAAAGCACCAGTCGCCGAAATCAAAGTACCAGAAATTCCTGCCAAGCCAAAGGATCCACGTCGAGTTGAGGTAGTGGATATATCTCAACTGGCTGGCACTGCCGTTAACCCCTTTCCATCGGTATCTGTATCCTCGTGGTCTCCGCAAGACGATTTCTCCAAAAACGAAGGCCAGCACATTTGCCCGGAATGTGgcaaaaactttaataaaatcgcCGGTTTAAAACTTCACATAAAAACTGTACACGATAAGGTCAAGGACTTTGCCTGTCGCTTTTGTCCCAAGCGTTTTAGCAAGTCTTACCATCTCCGTCATCACGAGTATACGCATACGGGGGAGAAGCCCTACGAGTGCAAAGTATGCAATCAAAACTTCAGACACGATGCAACCTTAAGAAAGCATATGGAGTCACACAACAGACCTCGAAAAGAGCCAAAGGAGCCAAAGAAACCAAAGCCCAAGCCAAAAGATCCCTCGAAAGATCCCCAGGTGCCCAGAGTGCGACTGAATACGGAACCAGTAAAAAATTACGAACAGTACCAAGATCCAGATGCAGAGCGAGCGGCAGCAACGGCTCAGTTGATCGCCCAACAGCTGGAAGAGAGCGAGGCGAAGCGTCAGGCGGAAGCGAAAACCCGGGAGATTCAAGAGGCAGCGTGCGAGCAGCTCCAgaaattgcagcaacagcagattTCATATGATAGCTTCACTAAATGA
- Protein Sequence
- MNEETPPSIHTICRTCLSNLQQDEAFDLFAVPDLAKKLCVCTSLSVEHQDGFPRNLCTTCHSRLNDLHDFQKQCVDSVQKFKELVSRNCFIIQTVPEDDVVHEREHISFDPLLNTKLEIDNEEDVFKMIEDVDKESEDVDHLEDAFNDSGSDYHNEDENFQADSSDSDDEMPLSRLRGNSRAKSKKDDKNKPKEKPKRRRIPAAERHLHRTVECHICNQKFIKTSCYEEHMKHHNDQLPFQCTVENCKKGFTTSTGLKHHMEHTHTELCDLHPCTVEGCNESFAQTRMLTQHMRKVHNIAKPIIHPCPECDKVFRCPMALKKHMYNHTGEELPFGCNICQKRYRVNTELRDHLLRHAGIKNFVCPYCGVGKTTKQELDKHMLTHTKEKKFKCDQCDHSSSSKQRMSKHIKVVHLKIKDFVCQYCPKSFSTAYDCKIHERLHTRNDCFECSICGRNFLFESRLTKHLRTHEKRKNKSATSSKKTETDGDEQTESKAPVAEIKVPEIPAKPKDPRRVEVVDISQLAGTAVNPFPSVSVSSWSPQDDFSKNEGQHICPECGKNFNKIAGLKLHIKTVHDKVKDFACRFCPKRFSKSYHLRHHEYTHTGEKPYECKVCNQNFRHDATLRKHMESHNRPRKEPKEPKKPKPKPKDPSKDPQVPRVRLNTEPVKNYEQYQDPDAERAAATAQLIAQQLEESEAKRQAEAKTREIQEAACEQLQKLQQQQISYDSFTK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00586113;
- 90% Identity
- iTF_00601985; iTF_00523111; iTF_00575757; iTF_00534000; iTF_00528984; iTF_00507037; iTF_00585376;
- 80% Identity
- -