Basic Information

Insect: Drosophila quinaria
Gene Symbol: grau
Assembly: GCA_035047525.1
Location: JAWNPO010000268.1:9334670-9337322[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.027 2.1 9.3 1.1 6 23 283 300 283 300 0.98

2 9 5.7e-05 0.0046 17.7 2.9 1 23 306 329 306 329 0.93

3 9 0.00011 0.0091 16.8 2.6 1 23 337 359 337 359 0.98

4 9 0.00023 0.019 15.8 0.4 2 23 365 387 364 387 0.96

5 9 0.16 13 6.8 0.1 2 23 393 414 392 414 0.95

6 9 0.71 56 4.8 4.4 2 23 423 444 422 444 0.91

7 9 0.00011 0.0086 16.8 0.2 2 23 452 474 451 474 0.96

8 9 9.6e-06 0.00077 20.1 0.6 3 23 481 501 480 501 0.99

9 9 0.00069 0.055 14.3 8.5 1 23 507 530 507 530 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.027	2.1	9.3	1.1	6	23	283	300	283	300	0.98
2	9	5.7e-05	0.0046	17.7	2.9	1	23	306	329	306	329	0.93
3	9	0.00011	0.0091	16.8	2.6	1	23	337	359	337	359	0.98
4	9	0.00023	0.019	15.8	0.4	2	23	365	387	364	387	0.96
5	9	0.16	13	6.8	0.1	2	23	393	414	392	414	0.95
6	9	0.71	56	4.8	4.4	2	23	423	444	422	444	0.91
7	9	0.00011	0.0086	16.8	0.2	2	23	452	474	451	474	0.96
8	9	9.6e-06	0.00077	20.1	0.6	3	23	481	501	480	501	0.99
9	9	0.00069	0.055	14.3	8.5	1	23	507	530	507	530	0.98

Sequence Information

Coding Sequence: ATGATTTGCCGTCTGTGCCTAAACAGCGCCAACGACACCATTCACATATTTGAGGGCGTTGGGTTGTCCCTAAACGTTGCCACGGTGCTGGCCAAATATTTTTGGTTCCagCCGAAAAACGATGATCCGATATCGACCGATATATGTGTGGGCTGCTGGACACGCGTAAGCGACTTTAACGAGTTCTACTGCAGCGTGGAAAAGGCGCATCGTCTGCTCACTGAGCGTTTCTCGCTGAAAGGCGGCGGCGGAGGCGAGCTGGAGAAGGACAACAAGACAGGTGCGACAGGTGCTGATGCAGCCAAGGAACTGTGCCAGGACTCAAAGGAGTTTCTGGACCACAGCGATGGCGACGATGACTTGGAGCAGGACAATGCTGTCGAGGATTTGTATGGCAGTGAGAGTGAAGCAGCAGATGTGTCCTTTGGCAACGAGCAGTTTGTCAACGATGTGCTGACCCACCCGGAAGCTGACGAATCTCAGCCGGAAAATGTCATTGTAAAGCAGGAAAGCGGAATTGCGACTGTGCCGGAGCGTCGAGAGACACGTGCGACGCGTGCCAAAAGCAAAGCGAATCAATTGCTCGCCCATGAATCTCCTCCAGCTGCCACGCCCGTCAAGCGCAGGGGCAGATCCATGTCTGCCAAACACGATGACCACAGTGTCGAGGTTGAAGCGAAGAGCAAACGTTACGTGGATTATAAAATGTCCATGCTGGCGATTGATAAGAAGATAGCGCAACATATGCGTCTCACCTGCAGCGTTTGCCACGAGGGCCAGGAGACGTTTCTGTTGCTCTGCAAGCACATGCAGCAGGCGCATCATCGCAAGGGCTACGCCGTCTGTTGCAACAAGAAGTTCTACAAGCGATCCTTTCTCACCGATCACATCGATCGTCACAACAATCCCGAGAAATTCAAATGCAATCTCTGTGGCAGAACCTTTGCGGACAAGCAGTGTCTGCGCAATCATGAGCTGCTCAAGCATCAGCCCGAGGAGGAGAAGACATTCACGTGCGAACACTGCCCCAAGAGATATACCAAGCAGTATTTATTGGATCAGCACAGGATCATACACAAGGAACGCAATGTGCCCTGCGATCTGTGCGACAGGCGTTTCCCCAACGTTTCCATGCTCTGTACGCATGTGAAAATGGTGCACGGCAATTATGGCACAATGTGCGATATTTGTGCCCAAGTGATAAGAGGACGGGCTGCCTTTCAGCGCCATCAGCTGGAGCACGCTGGTATTACGGAGCCCAAGGTGCAGTGCGACATTTGCGGATCGtggcataaaaacaaatacagccTGAAGAAGCATGTGAGACGACACAACGGCAACTCGGAGGAGAGCACCTGCAACATCTGTGGCAAGGTGTCGCCCAATCGCAGCGCCATGTTGAGTCATCAGCGTTATGTGCACACCGATCGTGTCCATGGCTGCAGTGTGTGCAACAAGAAGTTCAAAAAGGCCATCAACCTGAAGGAGCACATGGCCACGCATACGGGCGAAGTGTTGTACAAGTGTCCACACTGTCCCAAGACCTTCAACTCGAATGCCAATCAGCATTCGCATCGGAAGAAGTGTCATCCCAAAGAGTTTGAAGAGGCGCGCAAGGCGCGTCTACAAAACCGTATGGCGCCCACGGCCAATGACAACAAATCCCGGGCAAGCATGATAACAATAACCACGTCGGGCGAGACAGACGGGGAAATGGAAACGCACAACATTCTGGTGACGACGACGGAGCATAGCGATGAGGAGGAATTCAAAGGCGAGGACATTGAGTTTATGCTGACGCTCAGTCCACAGCCAGCGGATTAA
Protein Sequence: MICRLCLNSANDTIHIFEGVGLSLNVATVLAKYFWFQPKNDDPISTDICVGCWTRVSDFNEFYCSVEKAHRLLTERFSLKGGGGGELEKDNKTGATGADAAKELCQDSKEFLDHSDGDDDLEQDNAVEDLYGSESEAADVSFGNEQFVNDVLTHPEADESQPENVIVKQESGIATVPERRETRATRAKSKANQLLAHESPPAATPVKRRGRSMSAKHDDHSVEVEAKSKRYVDYKMSMLAIDKKIAQHMRLTCSVCHEGQETFLLLCKHMQQAHHRKGYAVCCNKKFYKRSFLTDHIDRHNNPEKFKCNLCGRTFADKQCLRNHELLKHQPEEEKTFTCEHCPKRYTKQYLLDQHRIIHKERNVPCDLCDRRFPNVSMLCTHVKMVHGNYGTMCDICAQVIRGRAAFQRHQLEHAGITEPKVQCDICGSWHKNKYSLKKHVRRHNGNSEESTCNICGKVSPNRSAMLSHQRYVHTDRVHGCSVCNKKFKKAINLKEHMATHTGEVLYKCPHCPKTFNSNANQHSHRKKCHPKEFEEARKARLQNRMAPTANDNKSRASMITITTSGETDGEMETHNILVTTTEHSDEEEFKGEDIEFMLTLSPQPAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00602095;
90% Identity: -
80% Identity: -