Basic Information

Insect: Drosophila quinaria
Gene Symbol: ZNF526
Assembly: GCA_035047525.1
Location: JAWNPO010000415.1:3259988-3262026[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.25 20 6.3 0.3 1 21 323 343 323 344 0.95

2 10 4.3e-06 0.00034 21.3 1.3 1 23 352 374 352 374 0.99

3 10 0.0033 0.26 12.2 1.5 1 23 377 400 377 400 0.92

4 10 1.5e-06 0.00012 22.7 0.8 2 23 407 428 406 428 0.98

5 10 2.5e-07 2e-05 25.1 0.6 1 23 434 456 434 456 0.98

6 10 5.4e-06 0.00043 20.9 0.7 1 23 462 484 462 484 0.99

7 10 0.00056 0.045 14.6 4.0 1 23 490 512 490 512 0.99

8 10 0.00064 0.051 14.4 0.3 1 23 518 540 518 540 0.98

9 10 0.00013 0.01 16.6 3.7 1 23 546 568 546 568 0.98

10 10 0.0011 0.09 13.6 0.2 1 23 574 596 574 596 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.25	20	6.3	0.3	1	21	323	343	323	344	0.95
2	10	4.3e-06	0.00034	21.3	1.3	1	23	352	374	352	374	0.99
3	10	0.0033	0.26	12.2	1.5	1	23	377	400	377	400	0.92
4	10	1.5e-06	0.00012	22.7	0.8	2	23	407	428	406	428	0.98
5	10	2.5e-07	2e-05	25.1	0.6	1	23	434	456	434	456	0.98
6	10	5.4e-06	0.00043	20.9	0.7	1	23	462	484	462	484	0.99
7	10	0.00056	0.045	14.6	4.0	1	23	490	512	490	512	0.99
8	10	0.00064	0.051	14.4	0.3	1	23	518	540	518	540	0.98
9	10	0.00013	0.01	16.6	3.7	1	23	546	568	546	568	0.98
10	10	0.0011	0.09	13.6	0.2	1	23	574	596	574	596	0.97

Sequence Information

Coding Sequence: ATGGATGTGGAGAAGATATGTCGCACTTGCTTAAGCCTATCAGGACCATTTCTGTCCATCTATGATGGCGGAGCCGGCAGCTGTTTGGTCGACATGCTGCGCGAGTTCACCAGGACCAAGCCGCGTTGCGAGGATAATCTGCCAGGCAGAGTTTGCCTTAATTGCATCAGTGAAATTAACCACTGCTATTCGTTTAAGCTCAAATGCGAGAATTCCAATCGCACGCTGCGACAGCTGCTGCCAAATGCGCTGCCCGAGGAGCCCGACTTTGGGACAGCAGCGAAGCCAACGGTGGCCACAACAGATTCATCAGTCCAAACAGCACATGTCACCACATGCACAACTGAAGCACAAACGGATGAGGTGCACACAGCAGATGCGGAGCAAAACACCAGCATGGAGAAGCCCGTGGCAATCTGCGACGAGCCAGAGGATGTGGAAGAGTTTGACTATGAGTTCTCGGATGAGCAGGAGAACGAGGAGACGCCAACCAAAGTGACGAGCGCTGAGAACATAATACTGCATGTGGAAAAGGACGACATCAAGTATGAAACGGAAATGATCTATGACAAGAGCACAGGCGAGCTGCACGAACAGCAGGGCAAGATTGTGCCCAAACAGAAGGAGTACAAATATCGTCTGGTCAGCAATGGCAGTGGGGACACATACATTGCGCCAGAGCCAGCGCCGACACTTACCCAAGTGACAACACGCAAGAGCGCTGCCAagctgttgcagcagcagcaacaacaacagcagcagcaggaggaggagcaacCTTATCAGGACGATAATCCACAGAAATCGGAACAGCAGGAAACACAAACAACGAGCAAGCGCAGCACAAGACGTCGGCCTGCAGCACAActggaggagcagcagcaggagccaCCAGTCAAGCAACCAAAAAGAAGTGTACCCAGTCAATCCGTTAATGCATCCGAAACCGAAGATCTTAAGGCGAATTTCCATTGTGATCGCTGCAATGCCGGGTTTGTTCTGGAGAAATCCTTAGTTATCCACCGAAGGCAAAATGGTTGCACCAATCGCAGTTTCAAGTGCAACGAATGCGAGCGAGTTTTCGTCTCGCTGAATCATTTGACGGAGCATCAGGCCACGCACGCTGCACACAACTGTCAGGAGTGCGGAGTGCGATGCGAGTCCAAGGAGCAGCTGGGCAGGCACATGGTCCAGGCGCACAAACGCAATCTGCGAAATCAGTGCAACGTTTGCCAGAAGGTGTTCACGATGCTTTCAACGTTGCGGGATCACATGCGCATCCACACTGGCGAGAAGCCATTTGTGTGCAACGTGTGTGGCAAGGGCTTCACACAGAATGCCAATCTCCGCCAGCACAAGCTTCGCCACTCGGACATCAAGCGCTTCAAATGCGAGCTGTGCAATAATTCATTTGTGACCAAGGCGGAGCTGACTTCGCATGCACGGACACACACAGGTGTCAAGCCGTACGAGTGCGATGTTTGCTCCTCGCGATTCACCACCAGTTGCTCCCTGGCCAAGCACAAGCGTAAGCACACAGGGGAACGGCCCTATCCCTGTGATCTCTGCCCCATGCGCTTCACGGCCCTCAATGTGCTGAAGAATCATCGACGCACGCACACTGGAGAGCGACCATTTGTGTGTCCCTTCTGCTCCAAGAGCTTCACACAGCGTGGCGATTGCCAGATGCATCAGCGTACGCATCAGGGCgacaaaatatacatttgCCCAGTGTGCAGTGAGGAGTTCAAGTCCATGAATGATATGCGATCGCATTTGACAATTCATGAGCAGCAGGACAAGCGATTGGTACACTTCACCCTCCTCAGCAACAAAGAGAACGGCAATGCGACGACGCTAGAGGAGCGGGATGATGAGTCGGATACAGCAGACACGGACTTGATGTAA
Protein Sequence: MDVEKICRTCLSLSGPFLSIYDGGAGSCLVDMLREFTRTKPRCEDNLPGRVCLNCISEINHCYSFKLKCENSNRTLRQLLPNALPEEPDFGTAAKPTVATTDSSVQTAHVTTCTTEAQTDEVHTADAEQNTSMEKPVAICDEPEDVEEFDYEFSDEQENEETPTKVTSAENIILHVEKDDIKYETEMIYDKSTGELHEQQGKIVPKQKEYKYRLVSNGSGDTYIAPEPAPTLTQVTTRKSAAKLLQQQQQQQQQQEEEQPYQDDNPQKSEQQETQTTSKRSTRRRPAAQLEEQQQEPPVKQPKRSVPSQSVNASETEDLKANFHCDRCNAGFVLEKSLVIHRRQNGCTNRSFKCNECERVFVSLNHLTEHQATHAAHNCQECGVRCESKEQLGRHMVQAHKRNLRNQCNVCQKVFTMLSTLRDHMRIHTGEKPFVCNVCGKGFTQNANLRQHKLRHSDIKRFKCELCNNSFVTKAELTSHARTHTGVKPYECDVCSSRFTTSCSLAKHKRKHTGERPYPCDLCPMRFTALNVLKNHRRTHTGERPFVCPFCSKSFTQRGDCQMHQRTHQGDKIYICPVCSEEFKSMNDMRSHLTIHEQQDKRLVHFTLLSNKENGNATTLEERDDESDTADTDLM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537661;
90% Identity: iTF_00586111;
80% Identity: -