Basic Information

Insect: Drosophila quadrilineata
Gene Symbol: -
Assembly: GCA_018150725.1
Location: JAECWN010000407.1:1703647-1707414[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2 1.2e+02 3.3 6.4 2 23 370 392 369 392 0.96

2 18 1.4 80 3.9 0.0 1 23 399 424 399 424 0.93

3 18 0.063 3.7 8.1 3.6 2 23 435 456 435 456 0.93

4 18 6 3.5e+02 1.8 3.0 2 17 467 482 466 493 0.75

5 18 6.9 4.1e+02 1.6 0.8 3 23 497 518 496 518 0.92

6 18 0.00025 0.014 15.6 0.5 3 23 526 546 524 546 0.96

7 18 0.0002 0.012 15.9 0.5 1 23 554 577 554 577 0.98

8 18 0.00062 0.037 14.4 0.3 2 23 582 603 581 603 0.97

9 18 0.00065 0.038 14.3 0.3 1 22 651 672 651 675 0.90

10 18 0.12 7.2 7.2 0.7 1 21 680 700 680 701 0.94

11 18 0.54 31 5.1 1.6 1 23 720 745 720 745 0.95

12 18 0.04 2.3 8.7 1.6 2 23 761 783 760 783 0.93

13 18 0.0057 0.34 11.3 0.3 2 23 789 811 788 811 0.92

14 18 0.11 6.5 7.3 0.5 2 23 815 837 814 837 0.96

15 18 5.9e-05 0.0035 17.6 1.0 1 23 843 865 843 865 0.98

16 18 0.01 0.6 10.5 1.0 1 23 869 892 869 892 0.93

17 18 4.9e-05 0.0029 17.9 1.3 1 23 898 921 898 921 0.97

18 18 0.0066 0.38 11.2 2.3 3 23 931 953 925 953 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2	1.2e+02	3.3	6.4	2	23	370	392	369	392	0.96
2	18	1.4	80	3.9	0.0	1	23	399	424	399	424	0.93
3	18	0.063	3.7	8.1	3.6	2	23	435	456	435	456	0.93
4	18	6	3.5e+02	1.8	3.0	2	17	467	482	466	493	0.75
5	18	6.9	4.1e+02	1.6	0.8	3	23	497	518	496	518	0.92
6	18	0.00025	0.014	15.6	0.5	3	23	526	546	524	546	0.96
7	18	0.0002	0.012	15.9	0.5	1	23	554	577	554	577	0.98
8	18	0.00062	0.037	14.4	0.3	2	23	582	603	581	603	0.97
9	18	0.00065	0.038	14.3	0.3	1	22	651	672	651	675	0.90
10	18	0.12	7.2	7.2	0.7	1	21	680	700	680	701	0.94
11	18	0.54	31	5.1	1.6	1	23	720	745	720	745	0.95
12	18	0.04	2.3	8.7	1.6	2	23	761	783	760	783	0.93
13	18	0.0057	0.34	11.3	0.3	2	23	789	811	788	811	0.92
14	18	0.11	6.5	7.3	0.5	2	23	815	837	814	837	0.96
15	18	5.9e-05	0.0035	17.6	1.0	1	23	843	865	843	865	0.98
16	18	0.01	0.6	10.5	1.0	1	23	869	892	869	892	0.93
17	18	4.9e-05	0.0029	17.9	1.3	1	23	898	921	898	921	0.97
18	18	0.0066	0.38	11.2	2.3	3	23	931	953	925	953	0.92

Sequence Information

Coding Sequence: ATGTCGGAAAATAAAAGTAGAAGTGCAGAAATTCGTGCTAGCTGCCTTCATTGCTCTGTAGTGAATTCCAAAGATGCATATCAGGAGATATTCGATGATGTGGGCATTGAAATTGGCCTGCCGGATCTACTGTCCAAATATTTTCAAGTTACTGTCAAGCCCGATGCCGAAAAATCACAATTGTTGTGCCGTGAGTGTGTGAACACGCTAATAAGCTTCTTTGACATCGATGAACTGGAGCGGCGTCAAAATGCCGCTAATGCAGCAAAAAAGAACAAACCGCCGCCAATTACAAAAGCAGTCACGCCCACTGCGGCTGCAGCTTCAGCTGCCCTCAAAAAAGGTGTTCCATTGGCAGCAAAACCAACGCCGCCTGCAAATAAATCTCCTGTCGCTGCCGCCGCAGTCTCAGCCGCCAGTGCTGCCAAAGTAGCTATAAAGAAGCCAACAATGGCCAAGGCGACGCCATTGCCAGTTCCTGCTGCTGTGAATCTTGTCAAGATCGAGAGGCCTGTCGATGTGCGTGTGACCCGTGGGAAGGCGGCGGCAGCCACGGCACACTCCCTCAGATTTCCACCCAAGGCAAAGACATATGATGCCTCCACGGCCAAAGTGGAGAGCACGAAACGTCGCTCGAAGGAGACGACGCAGAGCAGGGATCAGGAGCAGATTAGCGCCATGATACGTGATATACTCAACGATGAGGAGGCGGCAAATGTCGATGACAAGTTTGCGGAGGCAGCGGCGACAGTTGAACAGTTGGAGGCAGCAACAGAGGAACTGCCTGAAGAGGAGCAGTCCAAGGAAGCGGAAGATGGTGATGATTTGGAGTTTCTGCTGGAGCAAGAAGAGGACGAACAAGAGGCAGAGCAGGATGAATCCTCAACAGATTCGGATTTGCCGCCTCTTAAGCTGGAAAAGAAGGCTGCTTCCAGTGCGACCAATGAGTCCCAGGACGACAGTCAAAGTGAAGACGGTGATTCCATAAAAGTGGAACCCTTCAACTTTGTGCTAATCAAAGACTCTGATGACATAAAAGATCTCTATGAATACCTCAGCAGCGTGGTGAAGACCTGCTTTGAGAGCTTGAGCTTCGACTGGGCCACCGTCTGCCGGCATTGCAAGCTCAAGTGTGGCAAGTTCGAGCATCTCCTGGCGCACATGCTCAAGTCACATAAGCTGCCACAGGACCGCTACATCTGTCCCATTGAGGGCTGCAAAACGGAGCTAAAGGGACGCAAATATCTGGCCATGCATCTGGTCGTGTTGCATGCCCCAGTGGCAGACATTCCCATCTATGGCAGCTGCCCAGAGTGTCACATGACCTTCTCCAATATCCTGCAGTACAACAAACATTCCTGCGCCCATGTCATCAAGAAGCGTCGCGGTATACGCCTCTATTGCGAAATGTGTGGCCTGGAATTTCCATCCTGGAAGCGCTTCAACTTCCACAATCAGTTCCATTTGGAGCGACACAGACCACGCGCTTGCTTCGTGTGCAACTATGCCAACACCAACATTGATGATCTCTTCCAGCATTTGCACTACACTCACGAACCGGAGGGCACACTCTTCTGTGATATCTGCGATAGAAATTTCCGGGATTCAGCGACTCTCATGGAGCACAACAAATCCCATTCAAATGTCAGCAGCACCACCTTCACTTGCAACGAATGCAATGCCAACTTCGAGACACGGGGACGCCTCAATGGACACATTCGCACCACGCATGGCAGCCTCATAAGCTGCGAGCTGTGCAGTCGGGAATTCGCCACGGAGGCCACCTACAACATACACATGAAGAAGCATCTGATCATAGAACGCGAGGTGCATGTCTGTAATTGCTGTGGGCTGCTCAGCGAGAATCATGCCAAGCTGCTGGCTCATATAGAGCATGAGGATTCGCCTTGCTTTGGTGCGGATATCTATGTGGAACTGTTGCGGGATGCCTACATCTGTGAATACTGCTCCGCCTACTACAAACAGAAGTCGGATCTGCGTGCTCACCGAGAGTCGGGAGTACATACGAATGGTGTCTTCGTATGCCAGCCATGTAACAAGGAGTTTGGGGACATGAAACTCTATCGCCATCACATTAGAAACTATCAGTTGCAGCGTGCAGATGTGGCGCATCGCAAGCTAGAGATTTGCCTGTACTATATGTGTGACTATGAAGATTGCTGTGAAGCCTACATCAACTGGAATTCCCTGTACACCCACAAGCGGCGTACACATGATGGTAGCTCCAAGTTGACGGCACAACCCAAGTTAGCTGAGTGGATCTGTCAGTTTTGCCAGAAGGAATGCCGCTCAAAGATGTCCTTGTCCGTGCATGTGGCACGCAGTCACAATAATAATAATCTCATTTGTCCCCTGTGTAAGGCGTCCTACAAGGATGAGCAGGCGCTGCAGAAGCATCATGCCTACTGGCATGAGCCCATGGAATGTAATCTGTGCCTGAAGCTGGTGAAGAATCGTCGCAACTACGACACCCACATGAATGTCGTCCATTCGAATAACAAACGCTACAACTGCGCCGTCTGTGAAAAAGGATTCTATCACAAAAGCGAAATGGAGGCACATCAGCGACTGCACAGTCAATCCTACAGCTGTGAGCAGTGCAGCTTCACCACCAAGAATAAAAAATCGCTTTCGGTACATGTCTTGGGACAGCATTACAGGCGCTTTGCCTTTGAGTGCAAGATCTGCTCGAAACGATTTGGACGCCGCCAGGGCATGACCAACCATATGCAGCGTGTCCATGGCTCCAAGTTTGTCTGTCGTAATCACTGCGAGAGTGGCTGTAACAAAGCCTACAACACCACAGCCCAATTGAATTTGCATGTGCGTAAGGTTCACAACACCAGCATCCTTATGGGAGAACCGCACGACGAAGAGAATGAACTGGATATGGAGCTGGAACAGCAGGAAAATCAAGAGGAGCATGAAGAGGTTCAGCAGGAGCATCAAAAACATCCCGCTAAGCCTGTAAATTCTGCCAAAAAACGATGCTTGAGTGTCGTCAAGGATACGGTCGAAGGGGATAATGACTATATCTCGGATTCAGAGATATTTGAGGAATTCCAAGAATTTAAGCGCAAAAAGTCATCGCCGCCCAAAAAACTGAAAGGAAAGCGCACATGA
Protein Sequence: MSENKSRSAEIRASCLHCSVVNSKDAYQEIFDDVGIEIGLPDLLSKYFQVTVKPDAEKSQLLCRECVNTLISFFDIDELERRQNAANAAKKNKPPPITKAVTPTAAAASAALKKGVPLAAKPTPPANKSPVAAAAVSAASAAKVAIKKPTMAKATPLPVPAAVNLVKIERPVDVRVTRGKAAAATAHSLRFPPKAKTYDASTAKVESTKRRSKETTQSRDQEQISAMIRDILNDEEAANVDDKFAEAAATVEQLEAATEELPEEEQSKEAEDGDDLEFLLEQEEDEQEAEQDESSTDSDLPPLKLEKKAASSATNESQDDSQSEDGDSIKVEPFNFVLIKDSDDIKDLYEYLSSVVKTCFESLSFDWATVCRHCKLKCGKFEHLLAHMLKSHKLPQDRYICPIEGCKTELKGRKYLAMHLVVLHAPVADIPIYGSCPECHMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCNYANTNIDDLFQHLHYTHEPEGTLFCDICDRNFRDSATLMEHNKSHSNVSSTTFTCNECNANFETRGRLNGHIRTTHGSLISCELCSREFATEATYNIHMKKHLIIEREVHVCNCCGLLSENHAKLLAHIEHEDSPCFGADIYVELLRDAYICEYCSAYYKQKSDLRAHRESGVHTNGVFVCQPCNKEFGDMKLYRHHIRNYQLQRADVAHRKLEICLYYMCDYEDCCEAYINWNSLYTHKRRTHDGSSKLTAQPKLAEWICQFCQKECRSKMSLSVHVARSHNNNNLICPLCKASYKDEQALQKHHAYWHEPMECNLCLKLVKNRRNYDTHMNVVHSNNKRYNCAVCEKGFYHKSEMEAHQRLHSQSYSCEQCSFTTKNKKSLSVHVLGQHYRRFAFECKICSKRFGRRQGMTNHMQRVHGSKFVCRNHCESGCNKAYNTTAQLNLHVRKVHNTSILMGEPHDEENELDMELEQQENQEEHEEVQQEHQKHPAKPVNSAKKRCLSVVKDTVEGDNDYISDSEIFEEFQEFKRKKSSPPKKLKGKRT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -