Dqud015301.1
Basic Information
- Insect
- Drosophila quadrilineata
- Gene Symbol
- -
- Assembly
- GCA_018150725.1
- Location
- JAECWN010000375.1:9587041-9590599[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0019 0.11 12.9 2.8 1 23 123 146 123 146 0.97 2 12 2.8e-05 0.0016 18.6 2.7 3 23 153 174 151 174 0.95 3 12 0.00026 0.015 15.6 4.8 1 23 179 201 179 201 0.98 4 12 5 3e+02 2.1 5.8 2 23 208 231 207 231 0.90 5 12 0.00041 0.024 14.9 1.0 3 23 241 262 240 262 0.95 6 12 0.002 0.12 12.8 0.1 1 23 268 291 268 291 0.95 7 12 0.051 3 8.4 0.1 5 23 307 326 302 326 0.90 8 12 4.4e-06 0.00026 21.1 0.8 1 23 355 377 355 377 0.98 9 12 2.2e-06 0.00013 22.1 2.8 1 23 383 405 383 405 0.96 10 12 1.8e-05 0.001 19.2 0.2 3 23 413 433 412 433 0.98 11 12 0.001 0.06 13.7 0.9 1 23 440 462 440 462 0.99 12 12 0.0003 0.018 15.4 3.9 1 23 468 491 468 491 0.98
Sequence Information
- Coding Sequence
- ATGGAAACGTGCCGCACTTGTGCAAAGTGCGATTTCGAAAATGGCAATAACAACTATTGGCTGGACTTGTTTCATCCAACCCGTTGGCAGAGTGAAATGGCTCAAATACGCATGGAGTTCGTTAACTGGAAGTTGCAGATTTCAGCCAATGACGAAACAATAGAAGATATCAACGATAACGATGACGAAAATGAACCCGAAACCAAATTCGAATCATTACAATTCGAGAGAGATGAATTCTCAACGGATTTGAATACACTAAGCATTAGGTATGCCTGCAAGTTCTGCTACAAGTCAAAGGAAAGCTATGAGCTGCAACACTTGCTGGTGGAGCACATCGCCAGTGCCCATGATCCCGACCAGCCGTATAACTGTCCAGAGTGCAGCGAGTGCTTCCAGGACGCTGCCTCTCGCACTGTTCACATGAAGAATTGCCATGTGGTCAAGCATTATGGTTGCGAGGTGTGCGGCAAGAAGTATAGCGATCGCCATAATCTGCAGCATCATGTCGAGAAATATCACTCGGAGACGGACTTCGAATGCACCATGTGCGAGAAACGTTTCTTCACCCGCAAGAGCCTCCATTACCACATGAACTGGCATAATCCGGACCGCCAGTTGAGATGCCGTCACACCGGTTGTGATAGACTATTCATCAATCAGCGACATCTCAAGTGTCATGAGGCAACCCACACCACGGGCTCCCGTAAAACGGAATACTGTGGCTTCTGTGGCAAAGCTTTCATTCATGTGAAGACACTACGCTGGCATATCTATAGGCAGCATGGCGGAGAGAAGCCCTTCAAGTGCGCCATCTGTACAGAGGTATTTGCATCGTATGCCGAGAAACGCATCCATATGCTGGAGTTGCATACAGAGAATCTGACGCATCAGGAGCGCAGCGAGTGTATGTTCCAGTCCTGCCGGCAGGAGTTCGACAGCGCACAGGAGCTCATCCAGCACATGGCAACGGAGCACTTACAGCGGGAACCAGCCACACCCATCATTGCCAACAACAAACGTGTGCTCCAACGGAAGGGGGAGCGACAATATACGGGTGTCTTCCAGTGCAGCAATTGCACTCAGAGATTCAATATGAAGTCGGCGCTGGAGCGGCATATGGCAGTGCATTCGGCGGATCGCATGCATGCCTGCACAGATTGCTCCAAGCGGTATAAGCGTGCCCAGGATTTGAAATGGCACATGAAGACCCATGCGAATGAGAAGCCCAACATTTGTACTGTCTGTGGCAAAGGATTTGCCCTGAAATATGTGTTGACGCAGCATATGCGAAGTCATGAGGTTCTCGAGAAGAACTTCAAGTGTGAGACCTGTGGAAGGGCGTATCTCTTTGAGAAATCCTTGCGCCTCCATCAGCGTGTCCACACAGGAGATACTTACTACAAATGCGATTTGTGCCAGGAGCGTTTCGTTACGCACATTAAATTTAAAACGCACATGAAGAAGGCACATGATACAAATCAGACACATGCCAAGGATTCGCTGGATGATTTGATTAACATTGTGATTTCCTAA
- Protein Sequence
- METCRTCAKCDFENGNNNYWLDLFHPTRWQSEMAQIRMEFVNWKLQISANDETIEDINDNDDENEPETKFESLQFERDEFSTDLNTLSIRYACKFCYKSKESYELQHLLVEHIASAHDPDQPYNCPECSECFQDAASRTVHMKNCHVVKHYGCEVCGKKYSDRHNLQHHVEKYHSETDFECTMCEKRFFTRKSLHYHMNWHNPDRQLRCRHTGCDRLFINQRHLKCHEATHTTGSRKTEYCGFCGKAFIHVKTLRWHIYRQHGGEKPFKCAICTEVFASYAEKRIHMLELHTENLTHQERSECMFQSCRQEFDSAQELIQHMATEHLQREPATPIIANNKRVLQRKGERQYTGVFQCSNCTQRFNMKSALERHMAVHSADRMHACTDCSKRYKRAQDLKWHMKTHANEKPNICTVCGKGFALKYVLTQHMRSHEVLEKNFKCETCGRAYLFEKSLRLHQRVHTGDTYYKCDLCQERFVTHIKFKTHMKKAHDTNQTHAKDSLDDLINIVIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00587589;
- 90% Identity
- -
- 80% Identity
- -