Basic Information

Insect: Drosophila quadrilineata
Gene Symbol: -
Assembly: GCA_018150725.1
Location: JAECWN010000407.1:21602796-21604829[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 1.4 80 3.9 2.5 1 20 136 155 136 156 0.94

2 10 2.4e-05 0.0014 18.8 1.2 2 23 201 222 200 222 0.97

3 10 0.00088 0.051 13.9 0.8 1 23 248 269 248 269 0.95

4 10 0.0002 0.012 15.9 0.3 1 23 275 297 275 297 0.98

5 10 9.2e-05 0.0054 17.0 0.7 1 23 324 346 324 346 0.97

6 10 8.8e-08 5.2e-06 26.5 0.9 1 23 352 374 352 374 0.99

7 10 0.00095 0.056 13.8 5.6 1 23 380 402 380 402 0.98

8 10 3.4e-06 0.0002 21.5 1.2 1 23 408 430 408 430 0.99

9 10 0.00021 0.012 15.9 0.0 1 23 434 456 434 456 0.99

10 10 0.00097 0.057 13.8 0.2 1 23 479 502 479 502 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	1.4	80	3.9	2.5	1	20	136	155	136	156	0.94
2	10	2.4e-05	0.0014	18.8	1.2	2	23	201	222	200	222	0.97
3	10	0.00088	0.051	13.9	0.8	1	23	248	269	248	269	0.95
4	10	0.0002	0.012	15.9	0.3	1	23	275	297	275	297	0.98
5	10	9.2e-05	0.0054	17.0	0.7	1	23	324	346	324	346	0.97
6	10	8.8e-08	5.2e-06	26.5	0.9	1	23	352	374	352	374	0.99
7	10	0.00095	0.056	13.8	5.6	1	23	380	402	380	402	0.98
8	10	3.4e-06	0.0002	21.5	1.2	1	23	408	430	408	430	0.99
9	10	0.00021	0.012	15.9	0.0	1	23	434	456	434	456	0.99
10	10	0.00097	0.057	13.8	0.2	1	23	479	502	479	502	0.95

Sequence Information

Coding Sequence: ATGCCAGGAAGGAGCTCTGACCTATCGGCAGGGGTCTCACACGTGGAAAAGAGGAGACAAAGCATCGCTGACCATTTCATAATTGATGCATGTTCCGAAGAGCTGTACTACTGTGAGGCTTGTGGCAATGACTTCGATAGCCTGGAATCCTATAACGAGGCGCACAGTGGTCCAAACGGTTGCACTGGCGCAACGGATACTGCATCCCATGGCATAATCCATGCTGACGATATCGTTGAGGATGATCTGATAGAGGAGCTGGACGAAGCTAGTGAACCACAGCTGTGGGAGGTATTGGATGATGTTGAGGTTGTCAGTCCCGTCAATGAGGTTGAACTGGATCTCGAGATAGAGGAGGGGCAGGATGAGCAGGAAGATGAGGAAGTCGTCAGCAGGTCAGAGCGTTACTTTTGCTTCGACTGCCACAGCATATTCGAGACCAGGCAGAGTGCCGAGGAGCACATGTGCCCCCAGGCAGAGGAAAGTGCGGAGACCGATGCCAAAAGCAAGAATGATAAATTCACCAAAACCCCGACACCGGTCAGACGCAAGTCGTCGGCTACCACCGCCGCTACCAATGGAACAAGCGGAACCTCCACAACTTGTCCCATTTGCAAAACGGTCTTCAGCTCGTCAAAGAGCCTCAAGTTCCACATGCGAATCCATAACAAACGCGAGTCCAAGTCCATACAGGATGCACTGCCTGTGGGTGCCCATCAACAGTACAGCGAACTGGATCAATTCTACTGCGAAATCTGCAACAAAAGCTTTGAACAGAACCTACTGAACGTGCACAAGGAGATGCACCAGAGCAACAAGCAGTATTCTTGTGGCATCTGCAATCGCAAATTCGAGAGCATCGTCAACTACGAGATGCATCTGAAGATCCATGAGCGTCCCAGCTCCACCAGCCATACCAACAAAGCCAATGATAACGCTAAGAAGTCCGCGGATGATAAGAAACCCGGTTTCGCCTGCCAATACTGTGGGCATGTCTTCGCTCGTCCCTACGAGAAGGTTAAGCACGAAAGGGTTCACACCGGAGAGAAACCGTATAGCTGTGAGGTTTGCGGTAAAACCTTTCGGGTCTCCTACTCCCTGACGCTGCATCTGCGAACGCATACCAACATTCGACCGTATGTGTGCACCGTGTGCAACAAGCGTTTCAAGTCGCATACAGTCTACTCACATCATCTCCGCATACACAGCTCAGAGCGGGAATACACCTGTGATAGTTGCCCCAAATCCTTTAGAACCTCTGTTCAGCTCTATGCCCACAAGAATACGCACACGAAACCCTATCAATGCGCTGTCTGCAATCGACCCTTTGCCTCCCTGTATGCGGTCAAGGGACACATGGCAACCCATCGAACGGATGGTGGCAAGAGTGGAGGCAACTTCTCCACCGGGAAGAGTCAACAGGTTGCCAACAAATATTGCTGCGTTACATGCGGGGCGGAGTACGCGCGTCCTTTTGCCTTGCGTCTGCACATGAAGGCCGCCCACGGTCAGTCCGAGGGTGCCGATATACGTATAGCCAAAGTACCCAATCACAATGTAGGGGAGCACGAGGACATAGGTGCCCCGGATACTGAGACGGCTGTACTTATAGCGGCGGCCAAAGGAGATACTACCTATCATCTGGACCCTGATGATAGTGATATAGAGGATATGGTAGATGTGGTTCCAAAATACGAGGAATGCATTGAGGTCTCCGCGGATGCATTTGATGTAGAAACGTTTCAGAACGAAGAGATTATCACCGATTGGCTGAAGTGA
Protein Sequence: MPGRSSDLSAGVSHVEKRRQSIADHFIIDACSEELYYCEACGNDFDSLESYNEAHSGPNGCTGATDTASHGIIHADDIVEDDLIEELDEASEPQLWEVLDDVEVVSPVNEVELDLEIEEGQDEQEDEEVVSRSERYFCFDCHSIFETRQSAEEHMCPQAEESAETDAKSKNDKFTKTPTPVRRKSSATTAATNGTSGTSTTCPICKTVFSSSKSLKFHMRIHNKRESKSIQDALPVGAHQQYSELDQFYCEICNKSFEQNLLNVHKEMHQSNKQYSCGICNRKFESIVNYEMHLKIHERPSSTSHTNKANDNAKKSADDKKPGFACQYCGHVFARPYEKVKHERVHTGEKPYSCEVCGKTFRVSYSLTLHLRTHTNIRPYVCTVCNKRFKSHTVYSHHLRIHSSEREYTCDSCPKSFRTSVQLYAHKNTHTKPYQCAVCNRPFASLYAVKGHMATHRTDGGKSGGNFSTGKSQQVANKYCCVTCGAEYARPFALRLHMKAAHGQSEGADIRIAKVPNHNVGEHEDIGAPDTETAVLIAAAKGDTTYHLDPDDSDIEDMVDVVPKYEECIEVSADAFDVETFQNEEIITDWLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -