Basic Information

Insect: Drosophila quadrilineata
Gene Symbol: -
Assembly: GCA_018150725.1
Location: JAECWN010000375.1:6089419-6094061[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 5.3e-05 0.0031 17.7 0.8 1 23 205 227 205 227 0.98

2 25 0.049 2.9 8.4 3.1 1 20 233 252 233 255 0.87

3 25 1.1 63 4.2 0.7 2 20 287 305 286 308 0.91

4 25 0.15 9 6.8 4.2 1 23 384 407 384 407 0.94

5 25 1.1 67 4.1 0.7 2 21 414 433 413 434 0.93

6 25 0.53 31 5.2 0.1 1 23 477 499 477 499 0.96

7 25 0.0011 0.067 13.5 1.6 1 23 577 599 577 600 0.95

8 25 0.053 3.1 8.3 0.2 3 21 611 629 609 630 0.92

9 25 0.074 4.3 7.8 6.0 1 23 639 661 639 662 0.95

10 25 0.00017 0.0097 16.2 0.4 2 23 694 715 693 715 0.97

11 25 2.3e-05 0.0014 18.9 2.6 1 23 723 745 723 745 0.98

12 25 0.015 0.89 10.0 1.0 1 23 902 925 902 925 0.95

13 25 0.056 3.3 8.2 0.2 2 22 933 953 932 953 0.95

14 25 0.046 2.7 8.5 0.3 1 23 962 985 962 985 0.93

15 25 8.7e-06 0.00051 20.2 2.3 1 23 1014 1036 1014 1036 0.98

16 25 8.1e-05 0.0048 17.2 1.6 1 23 1043 1065 1043 1065 0.98

17 25 0.26 15 6.1 0.0 2 20 1092 1110 1091 1112 0.93

18 25 0.016 0.96 9.9 3.9 1 23 1157 1180 1157 1180 0.96

19 25 0.011 0.65 10.4 0.9 1 23 1217 1240 1217 1240 0.92

20 25 0.018 1.1 9.7 4.5 1 23 1264 1287 1264 1287 0.97

21 25 1.4e-05 0.00084 19.5 0.1 2 23 1317 1338 1316 1338 0.95

22 25 0.00017 0.0099 16.2 2.9 1 23 1344 1366 1344 1366 0.99

23 25 2e-06 0.00012 22.2 1.9 1 23 1372 1394 1372 1394 0.97

24 25 6.1e-08 3.6e-06 27.0 2.4 1 23 1400 1422 1400 1422 0.99

25 25 0.00071 0.042 14.2 0.3 1 22 1428 1449 1428 1452 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	5.3e-05	0.0031	17.7	0.8	1	23	205	227	205	227	0.98
2	25	0.049	2.9	8.4	3.1	1	20	233	252	233	255	0.87
3	25	1.1	63	4.2	0.7	2	20	287	305	286	308	0.91
4	25	0.15	9	6.8	4.2	1	23	384	407	384	407	0.94
5	25	1.1	67	4.1	0.7	2	21	414	433	413	434	0.93
6	25	0.53	31	5.2	0.1	1	23	477	499	477	499	0.96
7	25	0.0011	0.067	13.5	1.6	1	23	577	599	577	600	0.95
8	25	0.053	3.1	8.3	0.2	3	21	611	629	609	630	0.92
9	25	0.074	4.3	7.8	6.0	1	23	639	661	639	662	0.95
10	25	0.00017	0.0097	16.2	0.4	2	23	694	715	693	715	0.97
11	25	2.3e-05	0.0014	18.9	2.6	1	23	723	745	723	745	0.98
12	25	0.015	0.89	10.0	1.0	1	23	902	925	902	925	0.95
13	25	0.056	3.3	8.2	0.2	2	22	933	953	932	953	0.95
14	25	0.046	2.7	8.5	0.3	1	23	962	985	962	985	0.93
15	25	8.7e-06	0.00051	20.2	2.3	1	23	1014	1036	1014	1036	0.98
16	25	8.1e-05	0.0048	17.2	1.6	1	23	1043	1065	1043	1065	0.98
17	25	0.26	15	6.1	0.0	2	20	1092	1110	1091	1112	0.93
18	25	0.016	0.96	9.9	3.9	1	23	1157	1180	1157	1180	0.96
19	25	0.011	0.65	10.4	0.9	1	23	1217	1240	1217	1240	0.92
20	25	0.018	1.1	9.7	4.5	1	23	1264	1287	1264	1287	0.97
21	25	1.4e-05	0.00084	19.5	0.1	2	23	1317	1338	1316	1338	0.95
22	25	0.00017	0.0099	16.2	2.9	1	23	1344	1366	1344	1366	0.99
23	25	2e-06	0.00012	22.2	1.9	1	23	1372	1394	1372	1394	0.97
24	25	6.1e-08	3.6e-06	27.0	2.4	1	23	1400	1422	1400	1422	0.99
25	25	0.00071	0.042	14.2	0.3	1	22	1428	1449	1428	1452	0.91

Sequence Information

Coding Sequence: ATGTTGCCGGCTAATATATGCCGAACATGTGCAGTGCACGATGATAATTTGCTGGCAGTGACGCAGTGCAGTGAGAAATATGCCACCAAAAGTTACTTTGACATGCTGCACGAATTAACACAAAACGATCCACTTATGGAAGACGTAGATGACGGTCTGCCAGGGGACATGTGCACGGAGTGCTTGCGTAAGCTGGAAGATGCCTACGCCTTCGTGCGACAGGCACGTCAAGTACATGCCAAACTGTTGCAGAAGGTTCGAGGGCAACTGGAAACCGAGTGCTTGCACGAAACTCCCATTGATATGGGCTTGCAGCAACACATTAAGGTTGAGGCAGACTTTGGATTCGAGTGTAAACAAAACCCACACGAATATCAACATACACCAGTTGTGTCCGTTTCCGATCTAAAGCTGCAGCCAGAGAGCGACAGTGACTGCTCTGCGAAGGAAGACTTCAAGACCCGCAAAGCCGGAAAGCTGAGACGCAGCAATCGGAAGCCAAAGTCGACCGCAGACAGTGAGACGGAGTCTACGGTGGTCATTCAGCAGAAGCGGCGACGTGGTCGCCCACCTCGTGCTGCTAAAAAGGAATCGGAAATCGAGAATAAACGTCATACCTGTGACGTATGTGGCAAGTCCTTCTCCTGGCTGCGTGACTTGCAACGCCATGCCCGCATCCACTTTGAGCAAGCCTCCTACGTGTGCGAGACGTGCGGCAAAGGATTTGTGCGCAAGGACAAGTACATGTTCCATCTGAAATGCCACGAGAAAACCCAAGCCAAAGCAATTCCTCTCCAGCTGAGCAAGGAAAAGCGCTTCGCTGAGCGCCTCTACAGCTCCCGGCCGCTGAAGCGAATAGAGTGTAAGCTATGCAACTTCAGGTGCCAGCGCATCGGGGATTTGCGTGACCATCTGCCTGTCCATGTCAATGTGGACACCTTAGAGCATCTGAGCGCAGACAGCGATGTGGTGAGGGAACACTTTGGTTGCCCGCCGCAATTAAATCTGGATCAGATCAAGCAACAGATTTGCGCCGATGTGGCCAAAGGAGGGCATCACCTGGACAAGTTCTGCGCCGTCGTGAATGGCCATGGCTACGAGCTCTGCTTAAGCGACTCCGATGAAAATTGTACTGACATGACCACACCTTATCAGTGTTTGTCATGCAATATGGAATTCAATCGAAAGCATGTCCTGATGCATCACACGCTGGAGAAGCATAACCAAGAAGTGCTGCAACGATGCGAAACATGCAATGTTGGATTTGTGTGCGCTAATCTGCTGAAGCGCCACCTTCAATCCCAGTGCCAGAACCAATGGAAGCGCCACAGTTGCGCCCACTGTCCGGGCAGATTCATCTGGCAGCAGAATCTCGTCCAACACGATTGCTCGGAACGCGCTGAACAGCTTGATCGGGAAAGTCGTCACTTCCAATGCGGCCTCTGTGATGTGCTGTTGCAGAGCATGTCAGCACTGCGAGCGCATCTAGTAAAGCATTCGGATGACCTTGAGTTCAACTATGGTGCGGCCTTCTTTAGGTGCAACTATCCCAGAGGTGTAGACTCCAGCCAGGCAGAGGAGGTGAACGCACGCATTTTGATGGATTTCGATGGGCAGGATTATGGGTGTTATTTCGATGCGAGCACTGCCAGTGGACAGGAGCTGGACTTCTTCGATTCTGACACGGACATTAGCGATGTGGATGAACAGCCATTAGGACCCGGCCTGCACTCGTGTAATCTGTGCGGTGTGAGTACCATACGGCGTGCAGAACTCATGTGGCATCAGCAGAACCATCACAGTGAAGCGGAGGCTTCCCACACCCATCTCTGCAGTACATGTGGACAGGGATTTGTGGCCGAGTCGCTGCTGGAGCAGCATCGGCAACGTGTCTGTGCCAAGCGGCATGCCAAATTTCATTGCGATCAGTGCAATCTCCACTTTATATGGGAGTCCAACTACCAGAGACATTTGAGAGTTCATCACGAGATGAAAACGGAAAAGGAAACGGAGATGGAACAAGTTGAAGAGAATGCACCAAGCATAGGACTAAAGAGCAAACGCCAAATATCCAAACTGCAATGCAGTCAATGTGATAAGGTATTTATCTGGCCAAAGGATCTGACACGGCACAAGCGAATACATCAGCCTCAAGCGCTGGCTCAGTTTCCCTGCGGCTTCTGCGAGAAGAAGTTTCATCGCAAGGACGGGCTCAAGTCCCATATGCGTGTGCACTGCAGCATAGATCAACAGCAGCAGCAGCTGGAGGAGGATACTGTGCCGGAGCAGCAAATCCATATCCCTCTAATTTTGAGTCAGCTATGCCGTCCCAATGGCTGTAAGCGTATTCAGTGCATGATCTGCCTGTCGCAGCATACAAAGATCTCTGATCTGCGTACACATTTGTCTGGCCATGAGTTCTCCGTGGAACTGTCCGCGGAGCGTGTTGTCAGTCTCGGTCGAGTTCTCTATCCCGAGCAGGATCCTGGTGCTGGTAATGGAGATCTGGACCTGGAGATGCGGCAATTGATGGAGCGAATACAGAATGATGTGGGCAAAGGTGTCGAGCTGGACAGATTCATTTCGATAACCAATGAATCAGGCATGGAACTGAGCTTGGATAGCAGCGAAACCGACTCGGACTCCGACTCTGAGACAATGTCGAACTCCTCTGCAATGGGAAGAACCGGTCAAGGCCGTGTCTACTCCTGTGATCTATGTGAGATTCACCTGTCCCGCAAGTATCTATTGTATGCCCATCAGCTGGAGCAGCACAACTGGGAAGAGGCCACCTTGGTATGTAGCCTGTGCCAGGCGAGATTCGTCAGTGCCCAGTTGCTGGACCACCATTATCGAACGCTCTGTCGGAATAGCCAGAAACGTTTCCTCTGTCGCAAGTGTCCGCTGCGATTCCGCTGGCGAGAAAACCTCAAGCTACACATTGACGTTGCCCATCAGGAAACTAATGGAGAAGCAACGACTGCGGGCATGAGCATTCAGTTGGCATTGAATGGCAACCCCATACTGCCCGTCGCCAGCTACAATTGCAACGAGTGCAACCGCAGCTTCAAGATGCAGAAGGATCTCACACGGCATACGCTGATGCATGCCAATGAGTCCAGCATCTTTAGGTGCCGCTGGTGTGCCCGTCGCTTCTACCGACAGTCCAATCTACTGCAGCACATCGAACGCCATGGCATTGTCGCCAGCCAGCTGCCCTATGCCGAGAGCCTACTCAATGCCAGTCGTCACCCGAATGGCCGGAAGTCCATCGAGTGCAAAGTCTGTGAGACAAGCTTCCTCAGGATGGCCGATCTGCGTCAGCATCTGACCGCTGCGCCGGTTGGAAGTCACCATGACATTAACTCTATGCTGAACTACTCGATTACCAATCAGTTGGGCTATGAGCTCCATTTGAACGACTCTGAGACGGACGAGGAGTCCAAGTCAGCGGATACGCCCTCCCACTACACGTGCGGTATGTGCCAGCTGCGGTGCATACGCAAATATGAACTGCATCAGCACCAGCAGGCGATGCATCGACTGGAACGGATTACAACCGGTTGTGATCAATGCATCTATAAAAGCGTCTGCCTGGACCTAATTGCTTACCACAAGCGGACGCAGTGCGGGAACTCTGAGAAGCGGTTTAAGTGCGATAACTGTGGCTACAGGTTCATGTGGGAGTCGAATCTACTGCGGCACAATCAATTGCAGCACCAGACCAATAGTCTGGTTGACATGTCTTCGATAGCACCGCAAGAAGTGGCCATCGCAGAGTGCCAGATATTCCACTGCGGTCAGTGTCCACGAAAATACAATCGGAAAGATCGCCTGGCGGCACATGTCAAGAAGTGTCATGGTCCGGGGGCAGGCTCTGCTGCAGCAGCAGCCCCATCCACAAAGAAGAACTCGTCCTCCATTGCTGCCAAGCAACAAAAGAGTTTCCTCTGTGCATTCTGTGGCAAGGCGGTCAGTTCATCTTCCAATCTCATCATCCACATACGTCGCCACACGGGTGAGAAACCCTTTAAGTGTGACTACTGCGAAATGGCCTTTCCCCGCTCTTCCGACTTGCAGTGTCATCGACGCACACACACGGGAGAGAGACCCCACATCTGTACCGTGTGCCAAAAGGCATTTGCCCGCTCCTACAAGTTGCAGCAGCACATGCGAATCCACAATGGTGAACGACCCTACAAGTGCACGTATTGTGATAAGAGCTTCACCCAGTCAAATGACCTGACGCTCCACATTCGACGTCACACAGGTGAGCGTCCCTATCAATGTGAAACCTGCGGCGAGCGTTTCATTCAGGGCACGGCCTTGAAGAATCATCGAAACCAGAGTGGTCATTTCGAGGCAACAGCTGGCCAACTACAGGATACGCCAAATTAA
Protein Sequence: MLPANICRTCAVHDDNLLAVTQCSEKYATKSYFDMLHELTQNDPLMEDVDDGLPGDMCTECLRKLEDAYAFVRQARQVHAKLLQKVRGQLETECLHETPIDMGLQQHIKVEADFGFECKQNPHEYQHTPVVSVSDLKLQPESDSDCSAKEDFKTRKAGKLRRSNRKPKSTADSETESTVVIQQKRRRGRPPRAAKKESEIENKRHTCDVCGKSFSWLRDLQRHARIHFEQASYVCETCGKGFVRKDKYMFHLKCHEKTQAKAIPLQLSKEKRFAERLYSSRPLKRIECKLCNFRCQRIGDLRDHLPVHVNVDTLEHLSADSDVVREHFGCPPQLNLDQIKQQICADVAKGGHHLDKFCAVVNGHGYELCLSDSDENCTDMTTPYQCLSCNMEFNRKHVLMHHTLEKHNQEVLQRCETCNVGFVCANLLKRHLQSQCQNQWKRHSCAHCPGRFIWQQNLVQHDCSERAEQLDRESRHFQCGLCDVLLQSMSALRAHLVKHSDDLEFNYGAAFFRCNYPRGVDSSQAEEVNARILMDFDGQDYGCYFDASTASGQELDFFDSDTDISDVDEQPLGPGLHSCNLCGVSTIRRAELMWHQQNHHSEAEASHTHLCSTCGQGFVAESLLEQHRQRVCAKRHAKFHCDQCNLHFIWESNYQRHLRVHHEMKTEKETEMEQVEENAPSIGLKSKRQISKLQCSQCDKVFIWPKDLTRHKRIHQPQALAQFPCGFCEKKFHRKDGLKSHMRVHCSIDQQQQQLEEDTVPEQQIHIPLILSQLCRPNGCKRIQCMICLSQHTKISDLRTHLSGHEFSVELSAERVVSLGRVLYPEQDPGAGNGDLDLEMRQLMERIQNDVGKGVELDRFISITNESGMELSLDSSETDSDSDSETMSNSSAMGRTGQGRVYSCDLCEIHLSRKYLLYAHQLEQHNWEEATLVCSLCQARFVSAQLLDHHYRTLCRNSQKRFLCRKCPLRFRWRENLKLHIDVAHQETNGEATTAGMSIQLALNGNPILPVASYNCNECNRSFKMQKDLTRHTLMHANESSIFRCRWCARRFYRQSNLLQHIERHGIVASQLPYAESLLNASRHPNGRKSIECKVCETSFLRMADLRQHLTAAPVGSHHDINSMLNYSITNQLGYELHLNDSETDEESKSADTPSHYTCGMCQLRCIRKYELHQHQQAMHRLERITTGCDQCIYKSVCLDLIAYHKRTQCGNSEKRFKCDNCGYRFMWESNLLRHNQLQHQTNSLVDMSSIAPQEVAIAECQIFHCGQCPRKYNRKDRLAAHVKKCHGPGAGSAAAAAPSTKKNSSSIAAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCEMAFPRSSDLQCHRRTHTGERPHICTVCQKAFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCETCGERFIQGTALKNHRNQSGHFEATAGQLQDTPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -