Basic Information

Insect: Drosophila putrida
Gene Symbol: hb
Assembly: GCA_037043535.1
Location: JBAMBI010000471.1:3164667-3167093[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0002 0.014 15.9 0.2 1 23 255 277 255 277 0.99

2 6 0.011 0.73 10.4 3.6 2 23 285 306 284 306 0.97

3 6 0.00029 0.02 15.4 5.0 1 23 312 334 312 334 0.98

4 6 0.038 2.6 8.7 5.3 1 23 340 364 340 364 0.93

5 6 0.00023 0.016 15.7 0.4 1 23 755 777 755 777 0.96

6 6 0.0034 0.23 12.0 0.2 1 22 783 804 783 807 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0002	0.014	15.9	0.2	1	23	255	277	255	277	0.99
2	6	0.011	0.73	10.4	3.6	2	23	285	306	284	306	0.97
3	6	0.00029	0.02	15.4	5.0	1	23	312	334	312	334	0.98
4	6	0.038	2.6	8.7	5.3	1	23	340	364	340	364	0.93
5	6	0.00023	0.016	15.7	0.4	1	23	755	777	755	777	0.96
6	6	0.0034	0.23	12.0	0.2	1	22	783	804	783	807	0.91

Sequence Information

Coding Sequence: ATGCAGAACTGGGAGACGAACACGGCATCAGCCAACTATGAGCAACATAATTCCTGGTATAACAGCATGTTTACAGCCAACATCAAGCAGGAGCCGATgtcccatcatcatcatcagcatcagcacgataataacagcaacagctgcaccAGCAGTCCACGACAATCGCCAAATCCGCCTAGCACACAACTGGAGCAATATctaaagcagcagcagcagcatcatcaacaacCCATGGATACACTTTTTGGAGCAGCAATGACGCCGTCGCCGAGCAATAATGATCAGAACAGTCTGCAACACTTTGATGCAacactgcagcagcaactgttgcagcagcagcagtatcAGCAACACTTTCAGGCCGCCCAAcaaacacagcagcaacatcatcaccTGGCATTGGGTGGTTTTAATCCTTTAACACCGCCAGGATTGCCCAATCCCATTCAACATTATTATGCCAGCAACATGCGGCCAAGCCCACAGCCAACTCCAACGGGGGCAgcgggagcagcagcaacaacagctggtgCTGCAGCCACGTTGCAAGCTGGCGATAAATTACAAGCGTTGACACCGCCCATGGATGTAACTCCGCCAAAGTCACCGGCAAAGTCGCAACAATCGAATGCGGAACCTGAGAAGGATCACGATCTTATGTCTAATTCGAGTGAGGACATGAAATACATGGCTGAGTCGGAGGATGATGACACCAACATACGCATGCCCATCTACAATTCGCATGGCAAGATGAAGAACTACAAGTGCAAGACGTGCGGCGTTGTGGCCATCACCAAGGTGGATTTCTGGGCTCACACACGCACCCACATGAAGCCCGACAAGATACTCCAGTGTGCCAAGTGTCCATTTGTCACCGAATTTAAACATCACCTGGAATACCACATTCGCAAGCACAAGAATCAAAAACCTTTTCAGTGTGACAAGTGCAGTTATACGTGCGTGAACAAATCCATGCTGAATTCGCATCGCAAATCCCACAGCTCCGTCTATCAATATCGTTGTGCCGATTGTGATTATGCCACAAAGTATTGCCACAGCTTTAAGTTGCATCTGCGAAAGTATGGGCATAAGCCTGGCATGGTGCTGGACGAGGATGGTACTCCGAATCCTTCGCTGGTAATTGATGTCTATGGCACTCGCCGTGGTCCCAAGAGCAAGTCCGTCTCTGGCAGCAGCTCAAGTTGCAGTGGTTCCAGCAAACGAAGCACTATTTCACTAGCAACttcccaacagcagcagcagcagcaaccagcaccagcaacatcgCAGTTGTCGTCAGCTCTGCAGGGATTCCCAGTGCAAGTgccggcagctgctgctcctctACCAACATCCGCTCCAGCTCAAGCTCCAGCTGCAGCGCTCGTGGCACACACTTCGCCGTCATCGCCAACCAAAAGTGCTGCCAGCACGGAGCAGGCGACAAACTTGTCATCGGCTCTGCTGCCGCCTTTAGCCAGCTTATTGCAACAGAACCGCAACATGGCTTTCTTTCCCTACTGGAATCTCAATCTGCAGATGCTCGCGGCACAGCAACAGGCTGCTGTTCTTGCGCAGTTGTCGCCAGGCATGCATGatcaattgcagcagcaacagaagcagcaacatctGCAGTTGCAACACAATTTGCCAGCTCACAGTgacaacgatgatgacgatgagaaCGAGGATGACTTTGAGCGCAAATCTGTTGACTCGGCAATGGATCTGTCCCAGGGCACACCCGTCAAGGACGATTACCACCAGCTGCCCCACAGCAGCCACTTGGCCATGAACCTAAAGGTGAATGACGACGATACGCCAGTGATAAGCAGTAGCACAGTCTCACGACGTAAGGGACGTGTTCTTAAGCTAGACACTTTGCTACAACTGAAATCTGCGGCAATGTTATCCCCGGAACAGCAGATAAAACTGCCCACAGCCTCATCTCCCATTGCCGGGAACAACGCGGTCAAACAACTGGCGGATGATCCTTGCTCCGGTGCCAGTTCGGCAGATGAATCGATGGAAACTAGCCATGTGCCACAGGCCAACACTAGTGGCAGCTCAACGGCATCTAGTTCCGGCAATAGCTCAAATGCCAGCAGCAATGCTGCTGCACCacctgccactgccactgcctctgTCTCAGCGCCCGTCTCTGCCTCGGTCActgccaatggcaatggcaatgccaatgccaatatTAACGCCTCTGTATCCAGCTCCTCATCCACCGCGGGCAGCTCACCGGCCATTTATGAATGCAAGTATTGTGATATTTACTTCAAGGACGCTGTCTTGTACACCATCCACATGGGATATCACAGCTGCGACGATGTCTTTAAATGCAACATGTGCGGCGAGAAGTGCGACGGACCCGTTGGTCTCTTTGTCCACATGGCCCGCAATGCGCACTCCTGA
Protein Sequence: MQNWETNTASANYEQHNSWYNSMFTANIKQEPMSHHHHQHQHDNNSNSCTSSPRQSPNPPSTQLEQYLKQQQQHHQQPMDTLFGAAMTPSPSNNDQNSLQHFDATLQQQLLQQQQYQQHFQAAQQTQQQHHHLALGGFNPLTPPGLPNPIQHYYASNMRPSPQPTPTGAAGAAATTAGAAATLQAGDKLQALTPPMDVTPPKSPAKSQQSNAEPEKDHDLMSNSSEDMKYMAESEDDDTNIRMPIYNSHGKMKNYKCKTCGVVAITKVDFWAHTRTHMKPDKILQCAKCPFVTEFKHHLEYHIRKHKNQKPFQCDKCSYTCVNKSMLNSHRKSHSSVYQYRCADCDYATKYCHSFKLHLRKYGHKPGMVLDEDGTPNPSLVIDVYGTRRGPKSKSVSGSSSSCSGSSKRSTISLATSQQQQQQQPAPATSQLSSALQGFPVQVPAAAAPLPTSAPAQAPAAALVAHTSPSSPTKSAASTEQATNLSSALLPPLASLLQQNRNMAFFPYWNLNLQMLAAQQQAAVLAQLSPGMHDQLQQQQKQQHLQLQHNLPAHSDNDDDDENEDDFERKSVDSAMDLSQGTPVKDDYHQLPHSSHLAMNLKVNDDDTPVISSSTVSRRKGRVLKLDTLLQLKSAAMLSPEQQIKLPTASSPIAGNNAVKQLADDPCSGASSADESMETSHVPQANTSGSSTASSSGNSSNASSNAAAPPATATASVSAPVSASVTANGNGNANANINASVSSSSSTAGSSPAIYECKYCDIYFKDAVLYTIHMGYHSCDDVFKCNMCGEKCDGPVGLFVHMARNAHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00569272;
90% Identity: iTF_00558227;
80% Identity: -