Basic Information

Insect: Drosophila pullipes
Gene Symbol: Glis3
Assembly: GCA_035043795.1
Location: JAWNMT010000272.1:134065-139296[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 8.5 5.4e+02 1.3 2.4 3 23 438 461 436 461 0.89

2 5 0.18 12 6.5 0.4 1 23 470 497 470 497 0.88

3 5 9.4e-07 5.9e-05 23.2 0.5 2 23 504 527 503 527 0.97

4 5 0.00093 0.059 13.7 0.8 3 23 535 557 533 557 0.92

5 5 3.8e-05 0.0024 18.1 0.4 1 23 563 587 563 587 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	8.5	5.4e+02	1.3	2.4	3	23	438	461	436	461	0.89
2	5	0.18	12	6.5	0.4	1	23	470	497	470	497	0.88
3	5	9.4e-07	5.9e-05	23.2	0.5	2	23	504	527	503	527	0.97
4	5	0.00093	0.059	13.7	0.8	3	23	535	557	533	557	0.92
5	5	3.8e-05	0.0024	18.1	0.4	1	23	563	587	563	587	0.94

Sequence Information

Coding Sequence: atgtcTTCCACAatgaagcaacagcaacttccACTATCCATTCCCAATCACAGTGCCGAGATgttcaccaaaaaaaaaacatacaatgAGAATGTTTGCTATGATGCCTTCATGTCGCCACCATTAAGTGCCAGTGTTGGCAAGGGACACGATGATTTTCAGGCGCCCAAAGTCAACTTCACCAATAATACGAATTTTACCTGCGCCGAATTGCAGTTTCCGGATTTTTCACATCTATGCTTCGCCACGGAGACACCGAACTCTGTGTTTAGTGACTATAATAACTATACGGGACCGGAACAGGATAGGGATAGGGATGAtattgtgtgtgctgctgccgGGCAAACGGGTATGCCCTATCAGCAGGGTCAGTACACTCAGCTAAATCGCGAGGATGTCTTTCGGTTCGAGCCGGAGGACATTGCGCGGCTAACGGCAGACAATGGAtgtggtggaggtggaggtggagccTTCACTGAATCGATGGATGGCTTAATGCAGGTGCCACAAACACCCTTCACGCCGTGCAGTGGGCCGAGCGGGTGTCAATTGGGTGGGATGGCCGCACAGGTTGTCGAGCCGGTCGAGTCGGTCGAGTCTTTCAATCAGGATATTGATTACTTTAATTATGATGAAGTTAATTGCCAATCAAAAAATCAATCACCCTGCTCGTCGCCACATTTGGACGCCTGGTTGAACTTTAACCTCAGCGAAATATCGCCGGCGGAAACATTGCGCGAATCCTCACCGAAATTAAGCAACATTTACGAACAACAACTGGCGCATATTAAAGTGgaacaaacacagacacaacaacagcaaaagttgcCATCAATGAACTCCACTTTTGGTACACCCAAGTGTACACCGGTGTGTGGCACCTACGGCGATTACTCCAATCTTTACAACAATCAAAGTGCTTacggaaatttaaatgaatacgGAACggaacattttcaaaataacatCTCACAAGTTATTGAGAAACCCAATCGTGAACATAAAGTTATTTGGACAATTGATGAATTGGATGAACTGAATGCAGCCCTGGTGCTCAACGATCAGGTTCAGCAGAACTGTGAGTCCAAATTTGATAAGTCTGACTTCGCATTGGACAATCTGCCAAGTGTAACAGTGGAGACCTTGAGCGAAGAGCAACTCCTGACGGCCAACATCAGAgatgatgacaatgacaatgacaaggATGACGATGACATTGATGATGTGTTTGCAGCACCCGTCGAACTGGAGAGGAGACCTGAATATGCCGATTCCATTGATGGTGAGATTGAGCAGCCCGGTTCGCTTATTTGCCACTGGTCCGAGTGCAACATGGAGTTCGCCCatcagcaaatatttgtggaGCACATCGAAAAGTGTCACGTGGATGTGCGCAAGGGTGAGGATTTTTCCTGTTTCTGGCTGGACTGCCCCAGACGCTACAAGCCATTCAATGCCCGCTACAAGCTCCTCATCCACATGCGAGTCCACAGCGGCGAGAAGCCCAATAAGTGTCCGTTTCCGGAATGCAATAAGGCATTTTCACGTCtggaaaatttgaaaattcatCAACGTTCGCACACAGGCGAACGGCCTTATGGCTGTCAATATAAGGGTTGCCTCAAAGCGTTTAGCAACAGCTCGGATCGTGCAAAACATCAAAGAACACACTACGATACGAAACCCTACGCCTGTCAGCTGCCTGGCTGCACCAAACGGTACACGGACCCCTCAAGCCTGCGTAAACATGTCAAAAATCACGGACTTATGCGCCGCAAATCTGCCAGCGGTGGCGCCACATCCACGTCCTGCATCAAAAAGTCGGGCAAGACACGCCGCCATTCCGAATCGACTGCATTATCAACAAGGGGACCGTTGGTTGGCGCACCCCCCGTTGAGCAGCGTACacagcgcagcagcagttgcagcgaGGCAGCGCATTTGATCCAATTGGGTGGTGACCAGGATAAGGATATGCTAACGAGGGAAGTGGTGGCATCAACTTCGTCAACAACAGACCGCAACTATGTCTGCAGCAATGAGAATGTTGCAACTAATaacaattcaataaaatttaatgagttGTCAAATTGCATTGTCATCATTgagcaaaaccaaaatgaggcgacaccaacagcaactgcaacaacaattggctgTCACGATAATAgatacaacaacacaacaatcGCAGCGACGACTACATATGACGGGTttaactactacaacaacagtcgAGCTGGCGAAGGTGacaatgtaaataatatatattccgTAACGGAAACGGATACATTGagcacttgcagcagcagtgccagcaatagcaacaattataaaaccaACAATCAGGACAGCTGCAATCAtgataatattcataaatttaatgatcTGGAACATCTGCTAAATTCAACAACGGAACAGCACAATTTAAGCACTGATTTTAATACAACGGACAATAAGTGTCAATTGAATGAGTTCGTCTCATTCGAATATGTGCGAAAGTATCTAACGGATGCATTCGAGTCACCCAGCGCAGAGCACAGACCAAAGAGCCCAGTTACAAATTCTCAAATCGTCAATGATTTCGAAAATTAtgatattgaatttatttga
Protein Sequence: MSSTMKQQQLPLSIPNHSAEMFTKKKTYNENVCYDAFMSPPLSASVGKGHDDFQAPKVNFTNNTNFTCAELQFPDFSHLCFATETPNSVFSDYNNYTGPEQDRDRDDIVCAAAGQTGMPYQQGQYTQLNREDVFRFEPEDIARLTADNGCGGGGGGAFTESMDGLMQVPQTPFTPCSGPSGCQLGGMAAQVVEPVESVESFNQDIDYFNYDEVNCQSKNQSPCSSPHLDAWLNFNLSEISPAETLRESSPKLSNIYEQQLAHIKVEQTQTQQQQKLPSMNSTFGTPKCTPVCGTYGDYSNLYNNQSAYGNLNEYGTEHFQNNISQVIEKPNREHKVIWTIDELDELNAALVLNDQVQQNCESKFDKSDFALDNLPSVTVETLSEEQLLTANIRDDDNDNDKDDDDIDDVFAAPVELERRPEYADSIDGEIEQPGSLICHWSECNMEFAHQQIFVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARYKLLIHMRVHSGEKPNKCPFPECNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDTKPYACQLPGCTKRYTDPSSLRKHVKNHGLMRRKSASGGATSTSCIKKSGKTRRHSESTALSTRGPLVGAPPVEQRTQRSSSCSEAAHLIQLGGDQDKDMLTREVVASTSSTTDRNYVCSNENVATNNNSIKFNELSNCIVIIEQNQNEATPTATATTIGCHDNRYNNTTIAATTTYDGFNYYNNSRAGEGDNVNNIYSVTETDTLSTCSSSASNSNNYKTNNQDSCNHDNIHKFNDLEHLLNSTTEQHNLSTDFNTTDNKCQLNEFVSFEYVRKYLTDAFESPSAEHRPKSPVTNSQIVNDFENYDIEFI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567118;
90% Identity: iTF_00499892;
80% Identity: -