Basic Information

Insect: Drosophila pseudotalamancana
Gene Symbol: BCL11A
Assembly: GCA_037075185.1
Location: JBAMCK010000366.1:68725-82780[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.025 1.8 9.2 2.4 1 23 256 279 256 279 0.95

2 6 2.5e-06 0.00017 21.8 1.0 1 23 737 759 737 759 0.97

3 6 0.012 0.82 10.3 4.7 1 23 765 787 765 787 0.99

4 6 1.1e-06 7.6e-05 22.9 3.2 2 23 1079 1100 1078 1100 0.97

5 6 1.4e-05 0.001 19.4 3.3 1 23 1106 1128 1106 1128 0.99

6 6 2.6e-05 0.0018 18.6 0.4 1 22 1136 1157 1136 1157 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.025	1.8	9.2	2.4	1	23	256	279	256	279	0.95
2	6	2.5e-06	0.00017	21.8	1.0	1	23	737	759	737	759	0.97
3	6	0.012	0.82	10.3	4.7	1	23	765	787	765	787	0.99
4	6	1.1e-06	7.6e-05	22.9	3.2	2	23	1079	1100	1078	1100	0.97
5	6	1.4e-05	0.001	19.4	3.3	1	23	1106	1128	1106	1128	0.99
6	6	2.6e-05	0.0018	18.6	0.4	1	22	1136	1157	1136	1157	0.97

Sequence Information

Coding Sequence: ATGGAggtggagctggaactggagctggagctgggacTGGAGGCAAAAATGGGAGGTGATTCCGACTCGACAGAGAACGACGCGGTCGCCGCCCAGGACATTCTAACGTGCGGCGCCTGCCAGAAGACGTTCGCGCTGTCGGACATTGTCCGGTTCATACAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTATGGCCAGTGTTCGACACAGGCGCCCAGCATGGACCGGGACGCGGATGAGGGTCGTCCGCTCAGTCTGGTGAATCGCCGTCCCTCGATATCGGCCCCCATCACAGGCCGCAAcagcgccgccagcggctcacgcatacacacaccgCCGCCCAGTCCGGCGGATCTGCTGGCCGACGGCGCCAGCAGCACGCCCAAGCGCCTGGTAGATGAGAACGACAATACGACGCCGAAGGCGGACGGCGAACCGCTGACCACAGCTGGCGGCCTGCCGCTGGAGCCGCTCAGCCCGCAGTCGGAGCAGCCGCACATTGGCCGCGCCTCGGCTGAGGATTGCCCGCTGGACGACGACAAGCCAAAGGTCAAGCAGGAGCCCTACGCCGACGACGAGCTGCcccaagaagaggaagaggagcagcagcagccacagcagcaagaGAGGGAGCGGGAGCTGCCACATGATGAATcccagctgctggccacgcCGGACGATTGCCAACAGCCGCTGGCCAAGCGGCCCAAAATGGAGCTCGTCGATGCCGAGGCCAACACGGTGCACACAGAACCCAGCAACTACACCTGTTCCACCTGCAAGACCCGCTACACGTCCGCCTGGCGGCTCATCCAGCACGTGCAGCACTCGCACGGCGTCAAGATCTACGTGGAGGCAAGCGGCTGCGGCGGAGGCGCCACCTTGACCGTGGCCACGCCCGCCGCCCTCAATGCTGCCGcctcggcggcggcggcgaacGCGAGCCTCAGCTCCAGCCCCAATCGCAGTCTCAGCCCCTCGGCGGCGgtcgcagcagcggcggcagcagcagctgtcggcgtgccgctgccactgcacGCGCTGATGGCGCAGGCAGTCGCctctcagtcgcagtcgcagtcgcagtcgccggcgccaaagcgcagcagcagcaacagcagcgccgcCGCTTTGACTGTCGGCGGCTCTGCCTCGGCCaacacgagcagcagcagcaacgccagcagcggcaactcGCCCacacagcaactgctgcagcagcgcgtacaacagcagcagcagcagcaacaacagcaacaccagcaacagcagcagcaacagcagcagcagcagcagcagcaaagcatGGCCACAGCCATGGCAGCGGGAATGCGTCACCATCCGCTGCTGGCGCCGCCGGAGGCGATGCACGCCAATCCGTTCCAGCTGCTGCGCATGCCGCTGCCCCCGGCTCTGGCCCAGGCCAATGTAGTTCCTAGCGTGGCGCCCCTCTTCGGCCGCCCCTCGCCCGCCGATCACTACCGCATGGAGCAGCTGGTCAGCGAGCAGTTCCGGCACCACGGCTTCAAcctggccgccgccgccgccgcagcccAGGCGCAGTTCAATGCCAccacccagcagcagcagcagcagcagcagcaacagcagcaacagcagcagcagcagccgctgccaggTGTGGCTGTCAACGTTCCTAGCGGCGTGGAGCAGCGTCCGCCCtcgagcaacagcagccagcgcGGATCGGTGCCGCCCGCcgcgctgccgccgccgtcgctcagctcccagcagcagcagcaacagcagcagcaacagcagcaacagcaacagcagcaacataatcaacagcagcagcagcaaccgatTGCCGCCGCCGTGAGTCCAGCGGGCGCCGCCTTGAACTTGGAGCCACAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCAAGACAGAAGCAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCCGCTGCGCAGCTGTCGGCGACGCCGCGTCCGCACTCGCTGACGCCGCCGGAGAAGAGCGCCGAGAATGGAGCCGGCGGCCAGTTGGGCGCCCAGCTGGGCCAACAGCTGATCGGCACGCCGAGATCGGCCAGCACGCCGCCCAGCAAGCCGGATGCGGAACGCGCCGAGGCGGAGCTGGAGGCCAGCTGCTTTGCCTGCGGCTATTGCGACAAGAAATTTCGGTTCGAGAACAATCTGATCATCCATCAGCGGACGCACACCGGCGAGAAGCCGTACAAGTGCACCGCCTGCGACTTCGAGTGCTCCCACATCCAGAAGCTGATGAAGCACATGCGCGTCCATCGCAGCCCCGCCGAGGGCCAggacggcagcagcagcaatggcggCGACAACAATCAGGATGGCCACGACGGCGGCAGCAATGCCGATTCGCTGGAGACCAACGAGGCGGACAACGACGACGATCCCAATCCGGATGAGTCCGACGAGGAGCTCAACGATGAggacgtcgacgccgacgccgacggcgaggacgacgacgaggacgagctCGACGACTGCGAGGACGTCGACTACGAGGCCGAGGACCTGAGCGTCAACAATCGCATCGACGGCAAGAGCCAAAGCCCCAAGACCACCAGCTCCGGCGCCACCTCCCTCGTCGGCGAGCTGATGGACAAGTTCGGTCTCTCGAACATCGCCCAGTACTCGGAGGCCTACAAGCAGGCGCTGCAGGAGTCCGGCAGGAAGGAGGCGGCCGCCGTggccgcagccgctgctgccgccgcagccgtcgacaacaacaatcgcagcTCCGCATCCGCAGCTGGCGGTGGTGGCGCTGGTgccggaggcggaggcggaggcggaggcagtGCCTCGAACGCCGCCGGCGGCCAGCCGCTGGGTGACAAGCTGAACGGCCTGCCGGTGGCAGCGCTGCGACTGCGGGACGAGTTCGCCAAGAACTGCAACATGTtccagccgcagccgcaggaGGGTCCCGCCCAGGTGCCGCTCTTCAATCCGTTTCCCAATCCCTTCGAGCTGTCCAAGCGCATGAAGATCGACGGCGGCGACTGGTGGGGCATGTCGGCGCTCCACCGCAACGAGGCGCTCTTCGAGAACCTCAAGCTGAAGCCGCTCGGCCTCGGCGGCGCCAACGCGCTGCTGCAGGGTCCGCTGCTGAAGAAGGAGTCCCGCCAGCGGAACGACACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAACCTGACCGTGCACCGACGCAGCCACACCGGCGAGAAGCCGTACAAGTGCGAGCTCTGCTCCTACGCCTGCGCCCAGAGCTCGAAGCTCACCCGCCACATGAAGACCCACGGACGCACCGGCAAGGACGTCTATCGCTGTCGCTTCTGCGACATGCCCTTCAGCGTTCCCTCCACCCTCGAGAAGCACATGCGCAAGTGCGTCGTCAACCAGGGCAAggcggccgccgctgctgccaatgCCGCCAACGCCGTCGCAGCCGCCCAGGCGGCAGCTGCCGCCCAGCAGTTGCAGGCGGCTGCCcaggcacagcagcagcagcagcagcagcagcagcaacagcagcagcaacagcagcagcagcagcaacagttgcccaCACAGTCGCAGCTCTCGCCGCCCTGTccgatgggcgtggcagtgggctTCCCGCCGCAGTTCGGAGTCGGCGGCCACAACTTGTCGCTGGCGGGCAGCGTGAGCGGGGACAACGATTCGAACGCGTCCTCCAGCCTGCCCGCGCACTCCATTTCGCTCAAGGAGGAGGCATGA
Protein Sequence: MEVELELELELGLEAKMGGDSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVLQCNKENYGQCSTQAPSMDRDADEGRPLSLVNRRPSISAPITGRNSAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADGEPLTTAGGLPLEPLSPQSEQPHIGRASAEDCPLDDDKPKVKQEPYADDELPQEEEEEQQQPQQQERERELPHDESQLLATPDDCQQPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVEASGCGGGATLTVATPAALNAAASAAAANASLSSSPNRSLSPSAAVAAAAAAAAVGVPLPLHALMAQAVASQSQSQSQSPAPKRSSSNSSAAALTVGGSASANTSSSSNASSGNSPTQQLLQQRVQQQQQQQQQQHQQQQQQQQQQQQQQSMATAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPPALAQANVVPSVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNATTQQQQQQQQQQQQQQQQQPLPGVAVNVPSGVEQRPPSSNSSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQHNQQQQQQPIAAAVSPAGAALNLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSAAQLSATPRPHSLTPPEKSAENGAGGQLGAQLGQQLIGTPRSASTPPSKPDAERAEAELEASCFACGYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAEGQDGSSSNGGDNNQDGHDGGSNADSLETNEADNDDDPNPDESDEELNDEDVDADADGEDDDEDELDDCEDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVDNNNRSSASAAGGGGAGAGGGGGGGGSASNAAGGQPLGDKLNGLPVAALRLRDEFAKNCNMFQPQPQEGPAQVPLFNPFPNPFELSKRMKIDGGDWWGMSALHRNEALFENLKLKPLGLGGANALLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQQQQQQQQQQQQQQQQQQLPTQSQLSPPCPMGVAVGFPPQFGVGGHNLSLAGSVSGDNDSNASSSLPAHSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519433;
90% Identity: -
80% Identity: -