Dpse005130.1
Basic Information
- Insect
- Drosophila pseudotalamancana
- Gene Symbol
- ken1
- Assembly
- GCA_037075185.1
- Location
- JBAMCK010000356.1:222994-225237[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.047 3.3 8.4 4.8 2 23 219 240 218 240 0.97 2 12 0.00016 0.011 16.1 1.1 1 23 246 271 246 271 0.93 3 12 0.031 2.1 8.9 0.1 3 23 280 303 278 303 0.92 4 12 0.015 1 9.9 0.7 2 23 316 337 315 337 0.96 5 12 1e-05 0.00073 19.8 0.6 1 23 344 366 344 366 0.98 6 12 0.0062 0.43 11.1 0.1 1 23 372 394 372 394 0.98 7 12 0.019 1.3 9.6 2.6 1 23 400 423 400 423 0.97 8 12 0.0078 0.55 10.8 3.9 1 23 429 451 429 451 0.96 9 12 0.00095 0.066 13.7 2.9 2 23 458 479 457 479 0.96 10 12 2.7e-05 0.0019 18.5 1.8 1 23 582 605 582 605 0.95 11 12 0.012 0.83 10.2 0.7 1 19 611 629 611 633 0.95 12 12 4.1e-06 0.00029 21.1 1.2 1 23 639 661 639 661 0.98
Sequence Information
- Coding Sequence
- ATGAGCACAAACACAGTGTACTCTGTTCATTCAATATGCCGAGTTTGCCTAGAATATATCGATAGTAATGTTTATGACTTGTTTCTAATGCCAGACCTCGCAAAGACGTATACAGTATGCACATCCTTGCTAGTGGATCCCCAAGACGGTTATCCAAGGAACTTGTGTTCCAGTTGTTTTGCCAGAGTAAACGACCTCCATGATTTTCAGAAACTCTGTGTGGCTTCGGTGCAGCGCTTTAAGCAAATGGTAGCTAGCAATCGCGTCGTCGATGTCAATACAATTAACATATTCGAACCACTACCGGTGGCTAGCAACGAAGAAGATCTTCTGGCCAAGGATGAGCAACCAAGTAATGAATACGATCCGCTGTTAAGTCATAAATTGGAGTTGATTGACAACGAAGAGGTTGTGTTCAAGATGCTGGAGAACGTAGACAAGGAAGCACAGGATGTGACGGACGTTAAGCGAGGGTTGAGCTTAAGCGACTGCTCAACGGAGTGCAGCCTCAGTGAAGATGATGTACCTTTGGCAAGGCGCTTGCTTGACAAGAACAGTGAAGTGGAAAACGAAACAACATGTGAGAGATTGTCTAATCccaaagaaaaacgaaaacctATTCCAGCATCCGAGCGGCATCTACACCGCATTATCACCTGCCACGTATGCCttcaaaaatttaagaaacaaATCAACTACGACGAGCACATGAAGCACCACAATGAATTATTGCCCTATCAGTGTCATGTGGAGCACTGCAAGAAGGGCTTCACCACAGCGGCTGCACTGCGTCTGCACGTTGACTATGCGCACACGAAAAGCGCCGccgaaataccctgtacagttGAGGGCTGCAGGCTGTTATTCCCACGCAAACGACTGCTAACAATTCATCTAAAAAAAGTTCATAATTTGTCCCGCGCAAGTGTGCCACGCGCGGAGCAGCCGTGCAGCGAGTGTGGTGTCCTCTTTCGCTGCCCAGTAGCCCTGAAGAAACATATGTACAAGCACACCGGCCAGCAGCTGCCCTATCCATGCAACATTTGCGGGAAAGGCTTTCACATAAACAGTGCCCTTAAAAATCATTTGCTGCGCCACGCAGGCATCAAGAACTATGTCTGTCCATATTGTGGTGTGGGCAAAACCACGCGTCAGGAGTGGAGCAAACACatcctcacacacacgcaagagAAGATGTTTAAGTGCCAAATCTGTAACCATGCGACACACACGAAGCGTGCGTTGGACAATCATGTGAAGATTGTGCAcgagaaaataagaaattatgcCTGTCAGTATTGTGGCAAGACCTTTGGAAAATCGCATGCATGCAAAATCCATGAGATGACTCACACCGGAGAGAAGCGATGCGAGTGCAAGGTGTGCGGCAAGAAATTCCTGTACACAGAAAGCTTGACCAAGCATTTGAAAATACATGAGAAGAGTGTGGAACGTGCAATTGAGACCTACCGACAGCGGCAGGTTGAACTCAATATTTCAAACACAACAACCAAACAAAGATCCAGTGAAGTCCCTGATGCCCAATCGAAAAGTGAGGACAACGCAGCGAACCAGATACTGAAGGTCTGCGCAGAATCAGTGGCTACCATACCGCGCGATCCGCGACGTGTTGAGCGCGTCGACATTGCGCAGTTGGCTGGAACCGTTGTGAATCCCATTCCCGCCGTTTTGGTACCTTCGAATACGCCATCGCGAGTAACCATTTTGCAAAAGGAGGGCATGCATTTCTGTCCAGACTGTAACCAAGCGTTTAATAATTTAGGAAATATGAAGCGGCATTACAAGAGCGTCCATGAGAAGGTAAAAGACTTTGAGTGTCGCTTCTGCGCTCGTCGGTTTGCTAACTCGCAATCCCTTAAGCAACATGAGTGGATCCACACCGGCGAAAAGCCATATTCATGCTCGACGTGCGGCACCCATTTCCGTCAGGAGGCAGCATTAATTCGCCATCAGAAGGTGCACGTAGAGAAGCCACCTAAACCGGCAAAGCGTCCAAAGCAAATAACTGAAAAGTTTCGACAGAAGCAACtgcaaaaatgtgaaaaacggCGTAAGGTTGAAGCTCTGCGTCAAAAGATTGCTGAGGCTGCTAAAGAAGAGCTTCAGGAATTGGCCAAGCAGCGCGTgcttgaaaaacaacaaaatacctATGAACAGTAtcaggcggcggcggcggctgaaAAGACAGAAACAGAAGACGATCCGGAATCCGGAAGACAATAG
- Protein Sequence
- MSTNTVYSVHSICRVCLEYIDSNVYDLFLMPDLAKTYTVCTSLLVDPQDGYPRNLCSSCFARVNDLHDFQKLCVASVQRFKQMVASNRVVDVNTINIFEPLPVASNEEDLLAKDEQPSNEYDPLLSHKLELIDNEEVVFKMLENVDKEAQDVTDVKRGLSLSDCSTECSLSEDDVPLARRLLDKNSEVENETTCERLSNPKEKRKPIPASERHLHRIITCHVCLQKFKKQINYDEHMKHHNELLPYQCHVEHCKKGFTTAAALRLHVDYAHTKSAAEIPCTVEGCRLLFPRKRLLTIHLKKVHNLSRASVPRAEQPCSECGVLFRCPVALKKHMYKHTGQQLPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHILTHTQEKMFKCQICNHATHTKRALDNHVKIVHEKIRNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERAIETYRQRQVELNISNTTTKQRSSEVPDAQSKSEDNAANQILKVCAESVATIPRDPRRVERVDIAQLAGTVVNPIPAVLVPSNTPSRVTILQKEGMHFCPDCNQAFNNLGNMKRHYKSVHEKVKDFECRFCARRFANSQSLKQHEWIHTGEKPYSCSTCGTHFRQEAALIRHQKVHVEKPPKPAKRPKQITEKFRQKQLQKCEKRRKVEALRQKIAEAAKEELQELAKQRVLEKQQNTYEQYQAAAAAEKTETEDDPESGRQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00545421;
- 90% Identity
- -
- 80% Identity
- -