Basic Information

Insect: Drosophila pseudotalamancana
Gene Symbol: Znf639
Assembly: GCA_037075185.1
Location: JBAMCK010000602.1:2174-4200[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.014 0.96 10.0 0.4 3 23 289 310 288 310 0.91

2 10 0.00015 0.01 16.2 0.5 6 23 319 336 319 336 0.99

3 10 8.8e-06 0.00062 20.1 0.3 1 23 342 365 342 365 0.98

4 10 0.00012 0.0085 16.5 0.5 1 23 377 399 377 399 0.98

5 10 0.0003 0.021 15.3 7.7 1 23 406 429 406 429 0.96

6 10 1.2e-05 0.00086 19.6 1.8 1 23 435 457 435 457 0.96

7 10 0.096 6.7 7.4 0.5 2 23 466 487 465 487 0.96

8 10 5.4e-05 0.0038 17.6 2.8 3 23 494 515 492 515 0.95

9 10 5.3e-08 3.7e-06 27.1 0.7 2 23 522 543 521 543 0.97

10 10 0.00019 0.013 15.9 4.4 1 23 549 572 549 572 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.014	0.96	10.0	0.4	3	23	289	310	288	310	0.91
2	10	0.00015	0.01	16.2	0.5	6	23	319	336	319	336	0.99
3	10	8.8e-06	0.00062	20.1	0.3	1	23	342	365	342	365	0.98
4	10	0.00012	0.0085	16.5	0.5	1	23	377	399	377	399	0.98
5	10	0.0003	0.021	15.3	7.7	1	23	406	429	406	429	0.96
6	10	1.2e-05	0.00086	19.6	1.8	1	23	435	457	435	457	0.96
7	10	0.096	6.7	7.4	0.5	2	23	466	487	465	487	0.96
8	10	5.4e-05	0.0038	17.6	2.8	3	23	494	515	492	515	0.95
9	10	5.3e-08	3.7e-06	27.1	0.7	2	23	522	543	521	543	0.97
10	10	0.00019	0.013	15.9	4.4	1	23	549	572	549	572	0.96

Sequence Information

Coding Sequence: ATGATCTGTCGCTTGtgtttaaaaaacataaacgcAAACAATGCCGTCTACCTGTTCGAAACGAACGACACACTGGCCGAATCTTCGCTACTCAAGATGATAGCCAAATTTCTGCAGCTCGAGATAATGCCCGATGACAACATCTCGACGAACATTTGCCACGAGTGCTGCGAGCATTTGGAGGATTTCAATAACTTCTGGCAGCTGGTTGAACAAAAACAAGGAACACTGAAAAAGGAGTTTCTCAATGTGGATGTCGACTGTGTCGCGCTCAAGTGGACAGGCATCGATGTGGATGTCAACATTGACGAGCTGCCTCTGGTTGCCGACGAGATGGACGAGAAGCCATTGGATATACACAATCTTAGCCTGCTCGGCAGCGTACTCGATGTAAATGTGGACAGTGTGGAAGTGCCGCAGCTGGCGAATGTTCCAAAACAGTTTCAGAGTGAAAAGTTTATACAGCTGCATGCGGCCGATCCTACCGATGACGACGAAGACGATGCCGACGAGAAACCTATATTGCGAGACAGCATCGAAAGCGCGTTAAATGCTTCCACAGATGATGATGATGAAGTGCCGCTGGTTAAGCTGCAGCACAAGCTCAAGCCGAAGCGGAAAGCACGAGCGATAACACGCCGAAACAAGCGGACGCTAACCCTTGCCCAAGAGCTGGATCAGCTGCTGGATGATAGTGAACGCGATGGAAGCAGATCGCGTAGAAAAAAAGCCACACAAAATACTCCAACCGATACACAACAGAACGAACTGCAAGCGGCGCTGGAGCGCAAACCCAAAGGCTGCTCCCGGGCGCAGCTGACCCAGCGCTACGAAGAGGCGATCGCCAGCTACATGAACGCCGACTGTGATCTGTGCGACTTTAGCACCAAGTACCTGTCCCAGCTTAAAGTCCATTTCCTGGAGGTGCATCAGCGCGATGCGTATCTGAAGTGCTGCAACAAGGTCTTCAATCGCGCGTCCAAGCTGATGGATCACATACGGAAACACATTAATCCCAAGCTATTCACCTGTTCCATTTGTAATAAGTCGTTAAACTCACAAGATTATCTGGCCACCCACATAGAAACTGTACATAACAAAGTGGCCCAGATTGGCAAGGTGCTGAAGTATCCCTGTCCCAAATGCGAGCGCACCTTCAGCAGTGAGCGCCGTTTGGGCAATCATCTGCTTAAGCACGACACGGACCAGTTGGAGCACAGCTGTCACATATGCCACAAGAGTTTTGCGAATGTGCATCGACTGCGACGGCATATACAGTCCATACACGAGGACCTGCATCCACATGTCTGTGATATTTGCGGCAAAAAGTTTAAGTTCAAACCCTCCTTCGAGCGGCACCTGCTGGAGCATCAGGGAGTTGTGGCGCCAGCCATGGAATGCCCCGTGTGCGGCGTTTGGCTGAAGAACGAGCACAGCCTCCGGCTGCATCGCTTCACCCACGACAGCACCGACACCATCTGCCCGCACTGCTCGAAGACGTGCAGCTCGCGTACGGCGCTACGCGCCCACATCAAGTACGCTCACAAGCTGACGACAAATCTGCAATGCACCTACTGCGACAAGAGCTTTAAGCAGCAGCGCAACCTGGAGGAGCATATGGCCATACACACTGGCCTGCAGCTGTACAACTGCCCGCACTGTCCAAAGGAGTGTCGCAGCAGATCGAACATGTACGTGCACATCAAGCAGCGGCATGCGGACGAGTGGCTCAAGGCGAAGATGGCCCGCTCGCACAATCCGCAATTTAAGCCGCACGCCTAG
Protein Sequence: MICRLCLKNINANNAVYLFETNDTLAESSLLKMIAKFLQLEIMPDDNISTNICHECCEHLEDFNNFWQLVEQKQGTLKKEFLNVDVDCVALKWTGIDVDVNIDELPLVADEMDEKPLDIHNLSLLGSVLDVNVDSVEVPQLANVPKQFQSEKFIQLHAADPTDDDEDDADEKPILRDSIESALNASTDDDDEVPLVKLQHKLKPKRKARAITRRNKRTLTLAQELDQLLDDSERDGSRSRRKKATQNTPTDTQQNELQAALERKPKGCSRAQLTQRYEEAIASYMNADCDLCDFSTKYLSQLKVHFLEVHQRDAYLKCCNKVFNRASKLMDHIRKHINPKLFTCSICNKSLNSQDYLATHIETVHNKVAQIGKVLKYPCPKCERTFSSERRLGNHLLKHDTDQLEHSCHICHKSFANVHRLRRHIQSIHEDLHPHVCDICGKKFKFKPSFERHLLEHQGVVAPAMECPVCGVWLKNEHSLRLHRFTHDSTDTICPHCSKTCSSRTALRAHIKYAHKLTTNLQCTYCDKSFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQFKPHA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610817;
90% Identity: iTF_00531107;
80% Identity: -