Dpse010519.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila pseudotakahashii
Gene Symbol
-
Assembly
GCA_035046095.1
Location
JAWNOE010000167.1:1161024-1164885[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.00017 0.014 16.1 1.2 1 23 168 191 168 191 0.96
2 13 0.0018 0.15 12.9 3.1 2 23 240 262 236 262 0.90
3 13 0.011 0.89 10.4 0.9 1 23 355 378 355 378 0.92
4 13 0.053 4.5 8.2 3.2 2 23 427 448 426 449 0.94
5 13 0.00069 0.058 14.2 0.4 1 23 519 542 519 542 0.92
6 13 0.00069 0.059 14.2 3.3 2 23 593 615 593 615 0.96
7 13 0.21 18 6.3 0.1 1 20 702 721 702 723 0.95
8 13 0.00074 0.062 14.1 0.2 1 23 757 780 757 780 0.93
9 13 0.0024 0.2 12.5 1.5 2 23 830 852 829 852 0.95
10 13 0.019 1.6 9.7 1.8 1 23 943 966 943 966 0.91
11 13 0.03 2.5 9.0 1.2 1 21 1018 1038 1018 1039 0.95
12 13 0.88 74 4.4 0.4 2 23 1070 1094 1069 1094 0.82
13 13 3.7 3.1e+02 2.4 0.1 1 10 1112 1121 1112 1128 0.79

Sequence Information

Coding Sequence
ATGGAGGGCATGGATTTGTGGACGTCGATGTTCTCCTCCGATTTCGAGGAGGGTGAGCCGGAGGGCGGGGAGGCGGAACTGGAGGACAGCGAGCAGTACGGCAATGGCAATGATGATTTCCTCGGCGATTCAGAGATCCTGGATGCAGCTGATGCCATAGATGACCTGTTGGATGGCGAAGATGACGAAAGAGAGGAGGAGGGAGAGGATGAGCACTACGGAAATATCTCCAAGGGACCAAAGCAACCCGATCCCGATGACGATGCCCTCTTTGACTTCGAAATGGAACCCATTGTCAACATAGCGGAGCCACAGCATCCGGTTTTGGCTCCAGCTGGACCAATGGGTCAGCAGTTGCGTCCCACCATGCAGCGCCACTCGTTTCCCGGAACTATGGGTCGTCCCCGATTGGGTGCCGGACTCTCTGTACGGCCCACCACCTCGCAGATCAATGCCACGGATGAGAACGGGGTGCCCATTAACTACGAGCTGGGCGTGGTCTACATATGCCCAGCCTGCGGTGGAGAGTTCCGGCAACAGGACCACTGGAAGCGGCACATGAACCACATCCACAAGTACAACACCCTGCGTGGCCTGAACTTCACGCCGCTGGACAAACTGTATCAGCGCTGCAAGGAGTGCAACAAGCGGATCGCCATGCACAGTCGGGAGAACCTGCTGAAGCACAAGTTCACACACCTGCCTTTCCGTTGCACCAAGTGCTACATCTGCAAGCGGGAGTACAAATACAGGCAGGATCTAATGGTGCACCTGCGCATGGTCCACTGCGACGAAGTGGTTGCCATGATGCGGGAGGGATACAATGCTGCGGGACGCAAGACACGGGTTCGTGAATCGCGCACCGAGCAGTTGCAGCGGGAAAAGAGCTTTCGGGAAAATAATGAGTTTGGAGAGGACGTAGATCGCATCGAGGTGCGGAATGAGTTGCTCGAGCCGGATGCCGATGAGTCTGGCCTCCTGGAGCCTTTGCCTGAGAAGGATGCCAAGAAAAAACCTACCAGCAATCGAGGAGCAGCCGAACTGTGCGAGGACTACATACACTTCATGTGCCCCGACTGTGGTACCGAGTGTGACACCCATGCCCAGTGGAGCCAGCACATCGAGTTCGTCCACGACTATGTCAGCCGGCGGGGACTTAATTTCCGGAGCGTGGACATGCAGATGCAGTGCCTCGAGTGCAAAAAGATTGTGATTCCCAATACCATTAAATCACTGCGCGCCCACAAATTTAGCCATTTGTCGCAGCCCGAGTGGCTGCGCTGTAAACTGTGCTACAAGGGATACACGGATCATCAGGAAGTAATCAGACATCTGCTGCAGCATCACCATATGGACAAGCTGATGTCGGAGGACTGCGAGGAAGAAGATACTGAAGCTCCGTTGGCCATAATGGCAGAGGACGAATGCATCGAGGACAATGGAAACGGGGAGGGAAATGGCGCCACCTTAGACGAAGACTCTCCCTACTTTGAAGACGCCCCCAGACGCGGCGGTCGCATCAGCAGCGACGACATTTTCGAGCCTCACATCGACTACCTCTGTCCGCAGTGCGGCAAGGAGTTCATCGAGAAGAAGCACTGGCGCACCCACGTCGTTATGGCGCACGGCATGAACGATCTGACCAAGCTGAATTTCGAGATGATAAACGAACGGCAGCTAAAGTGCACTGCATGCGACAAGATCATTACCAATGCGTATGGCATCCAGAATGCCCAGCAGCACAGGATCACGCATCTTCCATTTAAGGCATACGCCAGGTGTCGCAAGTGTCACAAATCCTACACGGACAGGAAAGGTCTTGTAAAGCATCTGGCTACCTATCATCGCGTTGGATGGCCACAAAAAATGGGAGTATCTGCGCCACCACTAGATCCCAAATTCGCGCcctccaagaacccgatcaagCAGATCGTGACGGTGGCCAATGAAACGTACGAGATAATCTACCTGGATGACGTTGAGCAAGGCAACATGGAGGAGGAAAATGACTTTGGCGAACAGATGCAGGCGGATGAGGAGGACTTCCCCATTGCACCGCCTCCACCACCGCCAGCGCCGACCACGCAAAATAACCATCTTCGCTACAAGTGCGCCCACTGCGCCACTCTCTTCCCCACGCAGGCGGCTGTCCGAACTCACCTCATCGAAACCCGTTGCAGGAAGATAACTCTCAAGAGGCGTCGACAGACAATGATGAACTCACGAGCAGTAGACCCATCCGTTCCCACCGTGGAACAAAACTACATCTTCCTGTGCCCCTCCTGCGGCCAGGAGTACAAGACCCAGTTCGAGTGGCGCCGTCACATCAATGAGGTGCACAACTTTGACAAGCGCCAATACCTAAACATGCGACAGTTGGATAAGTTTCGCTACCAGTGCACCCAGTGCAAGGACATTGTGTGCAATTCGAAGCTGAAGGGTTTGCAGGACCATCACTTCCGCCATCTGCCCTACCGACTGTATCTGAAGTGCCTTATCTGCGGCACCTGTTACAATCACAAGCCGAACATAGCTGCACATTTGAGGGCTCGTCACAGCATCTACGACAGGGAGACGCCGGTGATGATCACCAAACCGAAGCATGCATATGGCCGCTACAAGGATAACAGTAGGGAGAAGCCCAGACTGCCCTCTCCTCCTCCGGCAGCGCCCTCTCCACCGGGCTGCTCCTCATCTGCTGCCTCCTCGGCCAGCAGTCGTTCCCTGAAACCCCAGCCTGGCGGCTTACCCACACGACCCGCTGGACTCAACACGCTGGAGGACAGCATCTCGTACCATAATGCCGTGGACTTGGATTTCATCACGTACTTCTGCCCCAAGTGTAATCAGAACTTCGACTCTCATGCCTTCTGGCGCAAACACATCGTGGAGCAGCACAACTTTAACAGCCGCGAAGGCCTCAACTTCCGGCAGATCGATAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGGGTGACCGTGACCCACACCAAGGGCGCCATCGGTCAGCTGCAGTCGCACAAGTTCCGCCATCTGCCGCACCGATCCTTCAAGTGCTTGACATGCGACGGCGAGTTTGTGCGCAAGCAAATGTTCTTCAAGCATCTGAATCGTGACACCAATCGATGTGACAATCGCCCGCAGCGGGATTTGGATGACGATGAGGCGGACCATGATTCGCAGCTAAGCTCCATCTACAACCTGTCGTGTCCGCAATGTGGTGACAACTTCACAACCAACAACAAGAAGCAGTGGCGCGAGCACATCAACGATTACCACGGTCTCACCAAGCTCGAACTTTTGCACATGAGCAAAGTGGGCGAGGACCTTTATCGATGCCAGGACTGCGACGAGGAGTTGCAAACAAATCGACAGTGGGTTCTGCAGTTCCATCGATTCCAGCACCTGCCCCACGCGGCCTATATCCGTTGCAAACTGTGCAAACAGAGCAGTGAGGCTTGCTCAGCAGCGGCGGGAGAGTTACACAGCCTACGTGAGCTGCTACAGCACCTCCGAAAGCACCATTCTGTGGTGGGCGAAAACGAGATGATAGTACTCCGAGAGCAAATCGCCATTGAGGAAAAGGAGCAGGAGGACACGGAACTGCCTGCAGACGGGGAAACCCAGGCTGCTGAGGATTCTGGACCGTATATGCCGTTGCCGCCGCATTTATTGGACGATGGGGACGACGTGGAATTCGAGGACCAGTATCTGCTGGGCTAA
Protein Sequence
MEGMDLWTSMFSSDFEEGEPEGGEAELEDSEQYGNGNDDFLGDSEILDAADAIDDLLDGEDDEREEEGEDEHYGNISKGPKQPDPDDDALFDFEMEPIVNIAEPQHPVLAPAGPMGQQLRPTMQRHSFPGTMGRPRLGAGLSVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNHIHKYNTLRGLNFTPLDKLYQRCKECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQLQREKSFRENNEFGEDVDRIEVRNELLEPDADESGLLEPLPEKDAKKKPTSNRGAAELCEDYIHFMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVIPNTIKSLRAHKFSHLSQPEWLRCKLCYKGYTDHQEVIRHLLQHHHMDKLMSEDCEEEDTEAPLAIMAEDECIEDNGNGEGNGATLDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHGMNDLTKLNFEMINERQLKCTACDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRVGWPQKMGVSAPPLDPKFAPSKNPIKQIVTVANETYEIIYLDDVEQGNMEEENDFGEQMQADEEDFPIAPPPPPPAPTTQNNHLRYKCAHCATLFPTQAAVRTHLIETRCRKITLKRRRQTMMNSRAVDPSVPTVEQNYIFLCPSCGQEYKTQFEWRRHINEVHNFDKRQYLNMRQLDKFRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLICGTCYNHKPNIAAHLRARHSIYDRETPVMITKPKHAYGRYKDNSREKPRLPSPPPAAPSPPGCSSSAASSASSRSLKPQPGGLPTRPAGLNTLEDSISYHNAVDLDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDGEFVRKQMFFKHLNRDTNRCDNRPQRDLDDDEADHDSQLSSIYNLSCPQCGDNFTTNNKKQWREHINDYHGLTKLELLHMSKVGEDLYRCQDCDEELQTNRQWVLQFHRFQHLPHAAYIRCKLCKQSSEACSAAAGELHSLRELLQHLRKHHSVVGENEMIVLREQIAIEEKEQEDTELPADGETQAAEDSGPYMPLPPHLLDDGDDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00592022;
90% Identity
iTF_00578912;
80% Identity
-