Basic Information

Insect: Drosophila pseudotakahashii
Gene Symbol: ush
Assembly: GCA_035046095.1
Location: JAWNOE010000198.1:639234-644386[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0075 0.63 10.9 0.0 1 20 320 339 320 341 0.90

2 9 0.0017 0.15 12.9 0.8 3 23 395 415 393 415 0.98

3 9 0.12 10 7.1 2.4 2 21 460 479 460 480 0.92

4 9 0.11 8.9 7.3 1.9 2 20 855 873 854 875 0.93

5 9 0.0071 0.6 11.0 0.0 3 21 926 944 924 945 0.92

6 9 0.0068 0.57 11.1 0.0 2 23 1013 1034 1012 1034 0.98

7 9 0.0031 0.26 12.1 1.2 1 23 1040 1062 1040 1062 0.99

8 9 0.00078 0.066 14.0 0.8 1 23 1115 1138 1115 1138 0.96

9 9 0.47 39 5.3 0.5 2 20 1256 1274 1255 1276 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0075	0.63	10.9	0.0	1	20	320	339	320	341	0.90
2	9	0.0017	0.15	12.9	0.8	3	23	395	415	393	415	0.98
3	9	0.12	10	7.1	2.4	2	21	460	479	460	480	0.92
4	9	0.11	8.9	7.3	1.9	2	20	855	873	854	875	0.93
5	9	0.0071	0.6	11.0	0.0	3	21	926	944	924	945	0.92
6	9	0.0068	0.57	11.1	0.0	2	23	1013	1034	1012	1034	0.98
7	9	0.0031	0.26	12.1	1.2	1	23	1040	1062	1040	1062	0.99
8	9	0.00078	0.066	14.0	0.8	1	23	1115	1138	1115	1138	0.96
9	9	0.47	39	5.3	0.5	2	20	1256	1274	1255	1276	0.91

Sequence Information

Coding Sequence: ATGTTCGCTGCGGTCGAGATGTCGAATTTCTGGCGAAGCGAGAGAtgcaaactgcaaactgcGACGCTTATCCGGCGGCTCCATCTGCATGCCATGTGTGTGCCATGTCCACGTCCACCGTCCACTGTCCACCGTTCACTTCCCCAGTCCGCCGCCATAATCTCGGCCAGCATCGCCGTTGGTCGTTATAATATTTCGCCGTGgccaaaacagaaacaaatcaGATGTCAGTTCGGTTCGGGGATTCTGGCCAACTTCGAACTTTTGCTGCGATCCGCGGGCCCTAATCATCAGTGGCCATTGGCCACCATGCGCTTTTCCTTCCCCCTCGCCCTCCCCATCCTGCTCCTTTTCCACCAGCGTTTTCCACATTCCAAAGATCTGAGCGCTCAGGAAATGGGCGaggagaagcagcagcaaatggAGGATCAACTGGAGGATCAGTTGGAGGACTCCAGCGACCCCCAAgagaacaacaataataacaataataataatgatgatgatggagaTGAAGATGGTGTCTTTGAGCAGCCAGAAGAGACTAATCCCGTGGAGGATCAGGATTTGGGGGAGACAGAGATGGAGCAGGATCAGGGTGATCAGCGGGAGGAGGTGGAGCAGCTGGAACTGCCTGCATTGAACAGTCCCAGCACTCCGCCCAGGAGTCCCATCTCCCCCCAGCTGATTCCCAAACTGGAGCAGCCCGCCACGCCGCCCtcggaggcggaggcggagcCGTCGCCATGTCCCTCGCCCTGTCCTCCCACCCCCACTCCCACGCTTACGCCCAAGTTCCCCAAGGTGCGTCTGAATGCGCTCCTGGCCTCGGATCCTGCCCTCAAGCCAGATGCCAAGGAGCTGACGCTGCCCGACTCCCGTCTCCTGGCTCCGCCACCACTGGTCAAGCCGGAGGCGCAGGCACCGCCGGAGGAGCCCCATCTAAAGCCAGCCCGATTCATGTGCCTGCCCTGCGGCATCGCCTTCAGTTCACCCTCGACGCTGGAAGCCCATCAGGCCTACTACTGCTCTCATAGGATTAAGGAGACGGACGAGGCGGGCAGTGATAAGTCGGGGGCAGGAGGATCTGCAGGAACAGCTGGCGATGGAGGATCCGGCTTATCCGGTGGCTCCGGCTCCGAGCCACCAGCCAAAATGGCCAGAACGGGAAAGCAATACGGCTGCACCCAGTGCTCCTACAGTGCCGACAAGAAGGTGTCGCTCAATCGCCACATGCGGATGCACCAGACCTCGCCGGCGGCTCCCACACTGGCCAGTCTGCCAAGTCTCCTCCAGAACGGAATACCACCATCGTTGCCAACCGTAACGCAGCCCCTTTCGCTGGAGGAAAGCCCTAGTCAACAGCAAACTGATCGCTACTGCAGCCACTGTGATATCCGGTTCAACAACATCAAGACCTATCGGGCGCACAAGCAGCACTACTGCAGTTCGAGGAGACCGGAGGGCCAGCTAACCCCCAAGCCAGACGCATCGCCGGGTGtgggaggagcaggaggaccAAGTGGCTCCACTGGACCCATGGTGTCTGCGCAAGCAGCTGCACCCGGCAAGCTGAGTCCGCAGGCCAGGAACAAAACCCCCACGCCGGCAATGGTCGCTGTGGCGgctgcagcagcggcggcggcggcctcCCTCCAGGCCACGACACACCCGCACCCGCCCTTCCTGGCTCTGCCCACCCACCCGATCATCATTGTGCCCTGCTCGCTGATCCGGGCGGCCAGCTTCATTCCAGGACCACTGCCCACTCCCAACACGGGGATTGTGAATCCAGAGACCACCTGCTTTACCGTGGACAACGGAACGATCAAGCCCCTGGCCACTGCCCTCATCGGCGCCTCCTTGGACCCCGAACGCCCCTCGGCTCCCTCGTCAGCTGCTGAGGCCACAGAACCCAAGAGCAGTCCACCGGAACCCAAGCGAAAGGAGGCAGGAGGAAGTCGcGAATCTGCGCCCTTGGATCTCTCTCTGCGTCGATCGCCCATCTCCCTGAACTCCCTGAGCTTGCGACAGCACCAATTGCGCAATGCCTTCCTCGATGTGGAGGAAGTACTCCTTGCCGGcgccggaggaggaggagggggaagTGTTAAGGATCACGTGGAAACTCCGCGAGGAGGTGGAAGTGTGACTCCCGAGCAGATCGTTTGCGCGCCCTCCCTGCCCTCGAGTCCTTCGATGAGTCCCTCGCCCAAGCGACGAGCCATCAGCCCACGCAGCTCGGGCGCTGGCAGTGCCTCCTCCATGTCGCCACCTGGTCTCAACGTGGCCGTGCCCCACATGCTCGACATGCGCTCCATGCTGCCGGCGGACTTTGGCCTCTCCGAATCGCTGCTGGCCAAGACCAATCCCGAGCTGGCTCTCAAACTGGCGgcggcagctgcagcggcGGCTGTGGCAGGCAGTGGTGCTGCTGGAGCTGCAGCCTTTTCCCCATCTCCTCTCGCTTCTTCTGCCCAGACGAGTGGAAATCTCGGAAGCGGAGGAGCATCAGGTGGAGGCGCCCAGCAGCCGCAAATCTATGTGAAGAAGGGCGTGTCCAAGTGCATGGAGTGCAATATTGTGTTTTGCCAATACGAGAATTACTTGGTCCACAAGCAGCACTACTGCTCGGCGAGAAGTCAGGAGGGAGGAGCGGGTGGAGGAGATGTGGATGTCAAGTCGGCCGTTTCACCTTCCAATTCTGGCGGAGGACTGGGAGCGGAGGCGTCTTCATCCGTGGAAACCACTCCGGTGGCCTACCAACAACTGATCTGTGGCGCCTGTGGCATCAAGTACTCCTCGCTGGACAACCTGCGGGCGCACCAGAACTACTACTGCCCCAAGGGAGGAGCGGCTGGAGCTGCTGCCTCCGCAGCAACGCCCTCGGATCCTGGACAGCTGGCCATGGTGAAGGAGAAGTGCGGAAAGTGCAAGAGCCTGCATGAGATTGGCCTGCCCTGTCCACCGCCCGTCACCAATCCACTAGCAGCACCCACCAGCAACTCCCAGCCCGCCGCCTCCAACAGCCTGAACAAGTGTCCCGTCTGCGGAGTGGTCAGTCCCACGGCAGCGCTGGCCAAGAAGCACATGGAGATGCACGGCACGGTGAAGGCCTATCGGTGCAGCATCTGCCAGTACAAGGGCAACACCCTGCGCGGCATGCGCACCCACATTCGCACGCACTTCGACAAGAAGACCAGCGATGTGAACGAGGAGCACTACATGACGTGCATATTCGAGGAGGAGGGCAGTTCCACGCTCAGCCAGGAGCTCCCTCCTGCAGCGGGAGCTTCGTCTGCAACGGTGGCCCACGATTCCGTGGATCACCCCTCTCAGATGTTCAACTGCGACTACTGCAACTATGCCTCCTCCTACAAGGGCAACGTGCTGCGACACATGAAGCTGATGCATCCGCATGTGGCCATCAACTCACCTTCGATTTCCCCCGACGCCAGAGATCAGGAGGTGTCCTCGATCACCACTCCCAACCAACACTCGAATTCCGATGGTTCCAACGGTGAGGCAGCCAGCTTCCACATCAAGTCGGAGCCCCTGGATCCTCCGCCGACGCTGAGCCTGGTGcatgacaacaacaactcgCCGATTCCGACGCCCCACATCAAGGCTGAGCCCATGGAGATCGGTGCGGATGTGACGTCGCCCGGTGGCGGGCTGGTTCCGCCGATGGCTTCTCCGCTCGGCAACAGCAGCGtggccgccgcagcagcagccgccgtCGCCGCCGCCGAGGTGATGAAGAAGTACTGCTCCACCTGCGACATATCCTTCAACTACGTGAAGACCTACCTGGCCCACAAGCAATTCTACTGCAAGAACAAGCCGATTCGCCCGGAGGCGAGCGACAGTCCCAGTCCGAATCATTTGGGCGGTGGAGGCGTGGCCGTGGGCCTGGGCATCGGCGGCATTGTGGGTGGTCAtggccagcagaagcagaacaAGGAAAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MFAAVEMSNFWRSERCKLQTATLIRRLHLHAMCVPCPRPPSTVHRSLPQSAAIISASIAVGRYNISPWPKQKQIRCQFGSGILANFELLLRSAGPNHQWPLATMRFSFPLALPILLLFHQRFPHSKDLSAQEMGEEKQQQMEDQLEDQLEDSSDPQENNNNNNNNNDDDGDEDGVFEQPEETNPVEDQDLGETEMEQDQGDQREEVEQLELPALNSPSTPPRSPISPQLIPKLEQPATPPSEAEAEPSPCPSPCPPTPTPTLTPKFPKVRLNALLASDPALKPDAKELTLPDSRLLAPPPLVKPEAQAPPEEPHLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRIKETDEAGSDKSGAGGSAGTAGDGGSGLSGGSGSEPPAKMARTGKQYGCTQCSYSADKKVSLNRHMRMHQTSPAAPTLASLPSLLQNGIPPSLPTVTQPLSLEESPSQQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPEGQLTPKPDASPGVGGAGGPSGSTGPMVSAQAAAPGKLSPQARNKTPTPAMVAVAAAAAAAAASLQATTHPHPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNTGIVNPETTCFTVDNGTIKPLATALIGASLDPERPSAPSSAAEATEPKSSPPEPKRKEAGGSRESAPLDLSLRRSPISLNSLSLRQHQLRNAFLDVEEVLLAGAGGGGGGSVKDHVETPRGGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSASSMSPPGLNVAVPHMLDMRSMLPADFGLSESLLAKTNPELALKLAAAAAAAAVAGSGAAGAAAFSPSPLASSAQTSGNLGSGGASGGGAQQPQIYVKKGVSKCMECNIVFCQYENYLVHKQHYCSARSQEGGAGGGDVDVKSAVSPSNSGGGLGAEASSSVETTPVAYQQLICGACGIKYSSLDNLRAHQNYYCPKGGAAGAAASAATPSDPGQLAMVKEKCGKCKSLHEIGLPCPPPVTNPLAAPTSNSQPAASNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEEGSSTLSQELPPAAGASSATVAHDSVDHPSQMFNCDYCNYASSYKGNVLRHMKLMHPHVAINSPSISPDARDQEVSSITTPNQHSNSDGSNGEAASFHIKSEPLDPPPTLSLVHDNNNSPIPTPHIKAEPMEIGADVTSPGGGLVPPMASPLGNSSVAAAAAAAVAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPIRPEASDSPSPNHLGGGGVAVGLGIGGIVGGHGQQKQNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505683;
90% Identity: -
80% Identity: -