Basic Information

Insect: Drosophila pseudotakahashii
Gene Symbol: Bcl11b
Assembly: GCA_035046095.1
Location: JAWNOE010000105.1:18369937-18382942[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.025 2.1 9.3 2.4 1 23 237 260 237 260 0.95

2 6 1.8e-06 0.00015 22.3 1.6 1 23 717 739 717 739 0.98

3 6 0.011 0.97 10.3 4.7 1 23 745 767 745 767 0.99

4 6 1.1e-06 9e-05 23.0 3.2 2 23 1027 1048 1026 1048 0.97

5 6 1.4e-05 0.0012 19.5 3.3 1 23 1054 1076 1054 1076 0.99

6 6 2.6e-05 0.0022 18.7 0.4 1 22 1084 1105 1084 1105 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.025	2.1	9.3	2.4	1	23	237	260	237	260	0.95
2	6	1.8e-06	0.00015	22.3	1.6	1	23	717	739	717	739	0.98
3	6	0.011	0.97	10.3	4.7	1	23	745	767	745	767	0.99
4	6	1.1e-06	9e-05	23.0	3.2	2	23	1027	1048	1026	1048	0.97
5	6	1.4e-05	0.0012	19.5	3.3	1	23	1054	1076	1054	1076	0.99
6	6	2.6e-05	0.0022	18.7	0.4	1	22	1084	1105	1084	1105	0.97

Sequence Information

Coding Sequence: ATGTACAACAAAATGCTGTCGATCAGTGAGGATCATGGATTCCGTTCGCTGAGCCATTCCGACTCCACAGAGAACGATGCCGTGGCCACACAGGACATCCTCACGTGCGGCGCCTGCCAGAAGGCGTTCGCCCTCTCGGACATTGTCAAGTTCATCCAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTACGGCCAGTGCGCCCAGAACACCCAGAATCCGCAGATGGATCGCGACGCCGAGGAGGGTCGTCCGCTGAGCCTCGTCAATCGCCGCCCCTCGATCTCCGCCCCCATTTCCGGTCGCAACACGGCCAGCGGCTCGAGGATACACACACCACCACCGAGTCCGGCGGACCTGCTGGCCGACGGAGCCAGCAGCACGCCCAAGCGTCTAGTAGATGAAAACGACAATACCACGCCCAAGGACAGCGAGACGGGCGCCACCACCCTCGATTCGAATGCCGCCCCCTCCAGTCCGGCGGCCATTGAGCGCCAGTCCTCGGGCGACAGCAGCTGcgagctggaggagcaggCGAAGGTCAAGCAGGAGCCCTACGAGGAGGAGGGCCTCCaccagcatcatcatcatcatgataacgatgaggaggaggacgaggagatGGAGGAGGAGCGGTCACTGGCCAAGCGGCCCAAAATGGAGCTGGTCGATGCCGAGGCCAATACAGTCCACACAGAACCCAGCAACTACACTTGCTCCACGTGCAAAACCCGCTACACCTCCGCCTGGCGCCTCATCCAGCATGTCCAGCACTCGCACGGCGTGAAGATCTACGTGGAGAGTCCCGGCGGATTGGGTGGTGGAGCCACCTTGACGGTCGCCACACCCGCCGCCCTCAACAGCAGTGCTTTGGCCttggccgccgccgctgccgccgcatCCGTTTCCGCCTCCGGCCTGGCGAGTCCACAGCCAGCGGTCAGCCCGAATTCGAATCCCCTTCCGCACCCAAGTCCCGCAGCAACATCGGCGGGCAAGCGAAGCAGTCCGGTGGCCGCCAACAACTCGGTTAGCTCCACTTGCTCCCAGTCCGCTTCCAATTCGCTGGCCAATACCAGCGGTGGCATCAGtaacatcagcagcaacaccagcagcaacattggctccccacaacagcagcagcaacagcagcagcagcaacagttgcagctgcagcagcaacagcagcgcgtgcagcagcagcagagggaGAACCTGGCCTCCGCCATGGCCGCCGGCATGCGTCATCatccgctgctgccgccgccggaGGCGATGCACGCCAATCCCTTCCAGCTGCTCCGCATGCCACTGCCTCCGGCATTGGCCGCGCAGGCCGGAAATGTAGTTCCTACGGTGGCGCCGCTCTTCGGCCGCCCCTCGCCCGCCGATCACTACCGCATGGAGCAGCTGGTCAGCGAGCAGTTCCGTCACCATGGCTTCAAtctggccgccgccgccgccgcagccCAGGCGCAGTTCAATGCGAACGGCGTGTCAGCCGTCGGCGGAGGTTCGGTGGTGGAGCCACGACCCCCCTCCtcggccagcagcagcggcagccagCGGGGCTCAGTGCCACCGGCTGCACTGCCTCCGGTGTCCCTCAgctcccagcagcagcagcagcaatccgtgcagcagcaacagtcgctgcaacagcaacagcagactACTccgcatcagcagcagcagcaacagcagcagcaatcccaacagcaacaacagttgCCCACTGGCTTAGTAGGCGGAGCAGGTGGCTCGCTGAAGCTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAGCACTGTTAACTCGAGCTCGCCGAGTCCACGACAGAAGCAATCGCCGCATTTCGCGAGCCCCTCGCcctcgcagcagcaacagcagcagcagcagcagcagcagttgcaacagcagcagcagcaacagcgacCCCATTCCCTGACGCCACCGGAGAAAATGCAGGGTGAAGCCAACAGCAGCTCGGAGAACGGAAGCGGAAGCGGCAACCTAAGCCTAATCCTCTCCAGCACTCCTCGCTCCGCCAGCACGCCGCCCTCGAAAACATCCGATGTTGCATCTCTGATGCAGGATGCCAGTCCCTTTGCCTGCAGCTACTGCGACAAGAAGTTCCGCTTCGAGAACAACCTGATCATCCACCAGCGGACGCACACCGGCGAGAAACCGTACAAGTGCACCGCCTGCGACTTCGAGTGCTCGCACATCCAGAAGCTGATGAAGCACATGCGGGTGCATCGCAGTCCGGGCGACGAGCAGGACCAGCAGGATGGCAACCAGGACGATGGCAGCAATGCCGATTCGCTGGAAACCAACGAGGCGGAGGACAACGACGAGGATCCCAATCCCGAGGAATCGGAGGAGGAGATGGGCGACGGTGAGGGCGATCTGGATGgcgaggatgaggacgaggacgagctGGAGGATTGCGAGGAGATGGACTACAAGGCGGAGGACTTGAGCGTGAGCAATCGCCTGGATGGCAAGAGCCAGAGTCCCAAGACCACAAGCTCCGGCGCCACCTCCTTGGTGGGCGAGCTGATGGACAAGTTCGGCCTGTCGAACATTGCCCAGTACAGTGAGGCCTACAAGCAGGCGCTGCAGGAATCGGGACGCAAGGAGGCAGCCgccgcagccgcagcagccgccgccgccgccgctgcatCGGATAATAACAATCGAGGTGGAGGCAATCCGGGCGACAAGCTGAATGGCCTGCCCGTGGCCGCCCTAAGACTGCGCGATGAGTTCGCCAAGAACTGCCAGATGTTCCAGCAGCCACAGGACGGCGGCGGTGCCCCCTCCCAGGTGCCGCTCTTCAATCCCTTCCCCAATCCCTTCGAGCTGAGCAAGCGCATGAAGATGGACGGCGGCGACTGGTGGGGCATGTCGCAGGCCCTGCACCGCAACGAGGCTCTGTTCGAGAACCTCAAGCTGAAGCCTCTGGGACTGGGAGGTGCCAACTCCTTGATCCAGGGACCGCTGCTCAAGAAGGAGAGCCGCCAGCGGAATGATACCTGCGAGTTCTGCGGCAAGGTCTTCAAGAACTGCTCCAACCTCACCGTTCACCGGCGCTCGCACACCGGCGAGAAGCCGTACAAGTGCGAGCTCTGCTCCTACGCCTGCGCCCAGAGCTCCAAGCTGACGCGGCACATGAAGACGCACGGGCGGACGGGCAAGGATGTCTACCGCTGCCGCTTCTGCGACATGCCCTTCAGCGTGCCCTCGACGCTGGAGAAGCACATGCGCAAGTGTGTGGTGAATCAGGGCAAGGCGGCTGCGGCAGCGAATGCCGTGGCTGCCGCCCAGGCGGCCCAGGCCGCTGCCCAGCACATTCAGGCCGCTGCCCAGCAGGCTCAGGCGGTCCAGGCGCAACAGCaatcccagcagcagcagcaacagcaacagcagcagcagcaactctcGCCCATGGGCGCCCATGGGGTGGTGGGCTATCCTCCCCAGTTCGTGGGCGGACACAACCTATCGCTGCCCGGCAGCGTGAGCGGGGACAATGACAGCAACGCCTCCTCCAGCCTCACAGGCGTCCATCCCATTTCGCTGAAGGAGGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTENDAVATQDILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQCAQNTQNPQMDRDAEEGRPLSLVNRRPSISAPISGRNTASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSETGATTLDSNAAPSSPAAIERQSSGDSSCELEEQAKVKQEPYEEEGLHQHHHHHDNDEEEDEEMEEERSLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESPGGLGGGATLTVATPAALNSSALALAAAAAAASVSASGLASPQPAVSPNSNPLPHPSPAATSAGKRSSPVAANNSVSSTCSQSASNSLANTSGGISNISSNTSSNIGSPQQQQQQQQQQQLQLQQQQQRVQQQQRENLASAMAAGMRHHPLLPPPEAMHANPFQLLRMPLPPALAAQAGNVVPTVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGVSAVGGGSVVEPRPPSSASSSGSQRGSVPPAALPPVSLSSQQQQQQSVQQQQSLQQQQQTTPHQQQQQQQQQSQQQQQLPTGLVGGAGGSLKLEPQQMDFYSQRLRQLAGTTSPGAGSTVNSSSPSPRQKQSPHFASPSPSQQQQQQQQQQQLQQQQQQQRPHSLTPPEKMQGEANSSSENGSGSGNLSLILSSTPRSASTPPSKTSDVASLMQDASPFACSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPGDEQDQQDGNQDDGSNADSLETNEAEDNDEDPNPEESEEEMGDGEGDLDGEDEDEDELEDCEEMDYKAEDLSVSNRLDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAAAAAAAAASDNNNRGGGNPGDKLNGLPVAALRLRDEFAKNCQMFQQPQDGGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQHIQAAAQQAQAVQAQQQSQQQQQQQQQQQQLSPMGAHGVVGYPPQFVGGHNLSLPGSVSGDNDSNASSSLTGVHPISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00578792;
90% Identity: iTF_00578792;
80% Identity: -