Basic Information

Insect: Drosophila pseudotakahashii
Gene Symbol: ham
Assembly: GCA_035046095.1
Location: JAWNOE010000108.1:7211057-7231439[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.015 1.2 10.0 0.0 2 22 340 360 339 362 0.88

2 9 0.041 3.5 8.6 5.4 3 23 371 392 369 392 0.92

3 9 1.6e-07 1.4e-05 25.6 1.7 1 23 398 421 398 421 0.96

4 9 1e-06 8.7e-05 23.1 1.6 1 23 427 449 427 449 0.97

5 9 1.9e-05 0.0016 19.0 4.5 1 23 455 477 455 477 0.98

6 9 0.0027 0.23 12.3 1.6 2 21 485 504 484 505 0.94

7 9 6.4e-08 5.4e-06 26.9 3.2 1 23 932 954 932 954 0.98

8 9 2e-06 0.00017 22.1 0.5 1 23 960 983 960 983 0.97

9 9 8.3e-06 0.0007 20.2 1.4 1 23 989 1011 989 1011 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.015	1.2	10.0	0.0	2	22	340	360	339	362	0.88
2	9	0.041	3.5	8.6	5.4	3	23	371	392	369	392	0.92
3	9	1.6e-07	1.4e-05	25.6	1.7	1	23	398	421	398	421	0.96
4	9	1e-06	8.7e-05	23.1	1.6	1	23	427	449	427	449	0.97
5	9	1.9e-05	0.0016	19.0	4.5	1	23	455	477	455	477	0.98
6	9	0.0027	0.23	12.3	1.6	2	21	485	504	484	505	0.94
7	9	6.4e-08	5.4e-06	26.9	3.2	1	23	932	954	932	954	0.98
8	9	2e-06	0.00017	22.1	0.5	1	23	960	983	960	983	0.97
9	9	8.3e-06	0.0007	20.2	1.4	1	23	989	1011	989	1011	0.98

Sequence Information

Coding Sequence: ATGCTGTTCGATCGATATGTCATATCAGGCTCCAGCGGCGACGACTTCGATCCAAGTGCGAGTGCAGTGcgtcaccatcatcatcatctccaTCACCTGGATCTGAGTGCGAGGAGCCAGGCCTTCAACTCGCTGCCTGAGCCCATTGAGGATTCATTCGCCGCCCGCCATCGCTTGTCGCAGCTGGATTCCGTGGAAGGATCGCCAACGAGGCGGGATCATCGGGACCTTCAGGAGCAGGAGCTTCTGCATCATCCCAATcatctccagcagcagcagcttcagCTTCGACAACAGCCACCGCCTCCGACGTTGCCGCTGTCCGTGGATCCGTCCTCTGGCGCCGACGGCATGGAGGCCTTGCTCAAGGAACACGCCCAGGCGACCCACATCCTGCAGGAGTGGGCGCGGAGGCGTGAACCCGTCTGTGATCTGGACATCCGCGATAGCGGCGGTGTCTACGCGAAGACGCCGCTCCAGAGGGGCACCCGCTACGGACCCTTCCCCATGAAGCTCAGCCACCAGCCCaacgatccgcagctggcgTGGAAGGCCAGCAGTAGGCATTATAATGGGTGGCTAGAGCCCACAGATGATGTGTCCACATGGTTGAAAAAAATCCGAAACGTTCAGGAGGACGATGGCATTGGCGAGGTTAATTTACAGAGTTACATTAATGGCGGTTATctGTGGTACGAGACGAATCGGTATGTGAATGCTGGCAGTGAAATGGTCGTCGACGGGCGACCCAAAAGTCCCGTTCAACTGAACGAGAACTTAATGAACGGCGGCAAAGTCctggcggcagcagcagcagcagccgccgcagTGGCagccgcctcctcctcgggAGCGAAGAGCGGGGGAGGGGGGAGCTCCCTGCCCAGCGATGACCGAAGCGATCGTGATAATGGCTCTTTGTACAGCGGTGACGAATTCTCCAAAGATAAGAAGAACTCCTCGCTAATCAGCCACGGAGATATCGATTTCACAGACGACGAAAACGGTTTCGATATACGCTGTGAGGTCTGTGATAAAGTCTATCCGGATTTAGAACTCTTGGACGATCATCTGGTGGGCGCTCATCATTTCAAGCAGGACGAAGTCCACTGTAAGCAGTGCACACTACGATTCTGCCATCGTTCTCTGCTGATCAAACACGAAGCAATCTCCCATAACAATATACGGAAATATTCCTGCGAGAATTGCAGCAAGGTATTTTGTGACCCCTCGAATTTACAGCGGCATATTCGCGCCTACCACGTCGGAGCTCGCTGTCATCCGTGTCCGGAGTGCGGGAAAACGTTCGGAACCTCGTCTGGCCTGAAGCAGCACCAGCACATCCACAGTTCCGTCAAGCCCTTCACCTGCGAGGTGTGCTCCAaggcgtatacgcaattcTCGAACCTGTGCCGGCACAAGCGCATGCACGTCACCTGCCGGACGCAGATCAAGTGCGACAAGTGCAACCAGAGCTTCAGCACCACAACCTCCGTGACCAAGCACAGAAAGTTCTGCGATTCGACGGGTCCCGTGTATCGGAACCAGCACGTGAATCGCCACCATCCGCACCCACTTCCGCATCAGCCGCACCAGCCGCATTTGGCCGCCACTGCCACATCCACCTGTCCGGCGACGCCAAGGGAGTCCCCGGAATCCTCGTCCTCagcagctgccgccgccgtTGCCGCCATGTCGACGCCGCCGAATCCCTTCCTAATGTTACGCGCCGCGCCACCATTCTTTCCCGGATTTCCACCATACGGATTTTCCGCCTTTATGCCACAAAATGCTCTGCATCCCAACAACTTTCCAATGTTTTTCTCGAAGAATCCCATGGACATGGGCTGTGCTGGACCCGAGATCACTTCCCCGATCTCCGCCTATGATCAGAAATTACCGTTTGGCTTTCTGAATGGCGAGGCCAGCAGTTCGCAGGCTTATGACAAAGTGCAGGCAGAAGAGTTGGCTTTCCAATCGGAGGAAAAACTAAAGGAGCAGCTCCTGCAAGTTTCCGAAGGCGAAGATGACGAGAGTCGCAATTCCCTGGACATGAAGATGAGATCGGAAGATGagaaaaatgaaacgaaatcTGAGGATCAGAGAGAGATGAAGCGGGAACCCGAGAGGGTGAACACTCCCGACCAGCAGCAGGTCGAAGATGATAGGAAATCCATTGACATCGTGAGCACTCCACCGCCAGCAGACACACCCTCTGGAGGAGACGGACCGCTGGACCTATCGATCTGTCGCAAGCGATCAGCTTCAACATGCCTATTCGCGCCCTTGGAAGAAAACCTCCTGCTCAATCGGTTTATGCCGAGAATACACGATTTCGAGGCCGAAAGGGAGCCGCCACTGAAAATGCGCAAGTCGCACAGTTCGGCGGAGTCGTCCATCTCGCAGAAATCGTTTAGGGGCAGCAGTCCCACGCCCACCGCCTCGCCGGGACCCACCCCCTCACCGTCGCCGCCCACGAGTGCGGGCGGGGAGCTGAGCAGCACGTCCGAGGGAGCAGCGGGACCAGCGACGACGGCGGCTGCGGCAGCGGTATCTGCAGCGGCGGGAGCAGTGGACCTAGCCGCACTGGCCCACCTAGCCCACCCGCAGAACCAGCCCACCATACATCCGCTCTTTCTGGAGGAGATCTACCGCACAGGGTTTCCTTTTTTATGCCCACCGGGCGGACGGCGCGGCATTGAGGCGCTGCTGGCGGGAGCCGCCAGTGCAGCAGCCCCAAAGCGGCCGCTTCCGCCCGTGAAATTCTCAACGGGACTCAAGACCAAGGATCGTTACTGCTGCAAGTTCTGCGGCAAGGTGTTCCCCCGATCGGCCAACCTGACGCGGCACCTGAGGACCCACACGGGCGAGCAGCCGTATCCCTGTAAGTTCTGCGATCGGGCCTTCAGCATTTCCTCGAACCTGCAGCGCCACGTGAGGAATATCCACAAGAAGGAGCGTCCTTTTCGCTGCGAACTCTGCGACAGAACCTTTGGCCAGCAGACGAATCTCGACCGGCACGTGAAGAAGCACGAGTCGGAGGGCAACAATTTCCGGGATTCGCCCAGTTCCACCGGCATTGCCGAACGGGAGGAGTACTTCGATGATATACGCAAATTCATGAACCGGGTCTACACGCCCAATAGCTTGGCCGGGAACGAGGGCGACACCGAGGAGTATCCCAACAGCGATGATCAGTCCGTGATCCTTGAAAAGGATAGCAGCAActtcaacaacaacagcagcaacatcagcaacaacaacagcagcagcaccggCAACAACAGCTCCAAGGCCATTACAATAAGCTCTTAA
Protein Sequence: MLFDRYVISGSSGDDFDPSASAVRHHHHHLHHLDLSARSQAFNSLPEPIEDSFAARHRLSQLDSVEGSPTRRDHRDLQEQELLHHPNHLQQQQLQLRQQPPPPTLPLSVDPSSGADGMEALLKEHAQATHILQEWARRREPVCDLDIRDSGGVYAKTPLQRGTRYGPFPMKLSHQPNDPQLAWKASSRHYNGWLEPTDDVSTWLKKIRNVQEDDGIGEVNLQSYINGGYLWYETNRYVNAGSEMVVDGRPKSPVQLNENLMNGGKVLAAAAAAAAAVAAASSSGAKSGGGGSSLPSDDRSDRDNGSLYSGDEFSKDKKNSSLISHGDIDFTDDENGFDIRCEVCDKVYPDLELLDDHLVGAHHFKQDEVHCKQCTLRFCHRSLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFTCEVCSKAYTQFSNLCRHKRMHVTCRTQIKCDKCNQSFSTTTSVTKHRKFCDSTGPVYRNQHVNRHHPHPLPHQPHQPHLAATATSTCPATPRESPESSSSAAAAAVAAMSTPPNPFLMLRAAPPFFPGFPPYGFSAFMPQNALHPNNFPMFFSKNPMDMGCAGPEITSPISAYDQKLPFGFLNGEASSSQAYDKVQAEELAFQSEEKLKEQLLQVSEGEDDESRNSLDMKMRSEDEKNETKSEDQREMKREPERVNTPDQQQVEDDRKSIDIVSTPPPADTPSGGDGPLDLSICRKRSASTCLFAPLEENLLLNRFMPRIHDFEAEREPPLKMRKSHSSAESSISQKSFRGSSPTPTASPGPTPSPSPPTSAGGELSSTSEGAAGPATTAAAAAVSAAAGAVDLAALAHLAHPQNQPTIHPLFLEEIYRTGFPFLCPPGGRRGIEALLAGAASAAAPKRPLPPVKFSTGLKTKDRYCCKFCGKVFPRSANLTRHLRTHTGEQPYPCKFCDRAFSISSNLQRHVRNIHKKERPFRCELCDRTFGQQTNLDRHVKKHESEGNNFRDSPSSTGIAEREEYFDDIRKFMNRVYTPNSLAGNEGDTEEYPNSDDQSVILEKDSSNFNNNSSNISNNNSSSTGNNSSKAITISS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00578702;
90% Identity: iTF_00578702;
80% Identity: -