Basic Information

Insect: Drosophila pseudoobscura
Gene Symbol: -
Assembly: GCA_009870125.2
Location: CM020869.1:21038877-21040806[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.063 4.8 8.0 0.7 6 23 267 284 267 284 0.99

2 8 4.5e-05 0.0034 17.9 0.7 1 23 290 312 290 312 0.99

3 8 0.034 2.5 8.9 5.5 1 23 321 343 321 343 0.96

4 8 0.00022 0.017 15.7 1.6 2 23 352 374 351 374 0.94

5 8 0.00053 0.04 14.5 0.0 3 23 382 402 381 402 0.96

6 8 0.00065 0.049 14.3 0.9 2 23 411 433 410 433 0.96

7 8 8.2e-07 6.2e-05 23.4 1.1 1 23 470 492 470 492 0.98

8 8 5.6e-05 0.0043 17.6 4.3 1 23 498 521 498 521 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.063	4.8	8.0	0.7	6	23	267	284	267	284	0.99
2	8	4.5e-05	0.0034	17.9	0.7	1	23	290	312	290	312	0.99
3	8	0.034	2.5	8.9	5.5	1	23	321	343	321	343	0.96
4	8	0.00022	0.017	15.7	1.6	2	23	352	374	351	374	0.94
5	8	0.00053	0.04	14.5	0.0	3	23	382	402	381	402	0.96
6	8	0.00065	0.049	14.3	0.9	2	23	411	433	410	433	0.96
7	8	8.2e-07	6.2e-05	23.4	1.1	1	23	470	492	470	492	0.98
8	8	5.6e-05	0.0043	17.6	4.3	1	23	498	521	498	521	0.98

Sequence Information

Coding Sequence: ATGCCGTGCTTCCTATGCACTCATCGTGTGGACGACGCCGTTAGCAATATAAAGTTCGATTCCGTCGAAGCTGACTCGCTCGGATTAAggcaaataattgaaaaacaCTTTTGGTTGCGgTTTAATGATTCTGTCGATGGCTACGTGTGCGGATCATGCTGGGAacaattgttgctgtttcacAACTTCTATTTAACCGTGGAGAATGCCCACAAAGCCCTGACCGAACTGGAAACAAAGCAGGCCGAGGAGAACGTCGCGGAGAATCAGACCACTCCAACAGCAGTAGTTGCAGCCGTTTATGGCGGTACTGCAAAGGATGAGAACGTGCAAAGCGTGGCAGCTGCGGTGAAGCGCAGGCGGGGTCGTCCCCGCAAGACCCGGGCTGCTTCAAGTGACGAAGAATTTCAGAACGTGCTGGAACAGATCAATTTGAACGAGATTAAAATTGAGTACCCCGAGGCAGATCTAACCATAGCTGATGTGCTGGAGGATCAGGAGGAGCAAGACTTTGAGTCACGCAGTGGCTGTGCCACGGAAGTTGATGATATTGAGGAACCTAAACCGAAAATCACTCGAAAGGTTCGTGGAAGGGGCCGCGGTCGTGGCCGAGTTCGGCTAGcggaaaagccaaaaaaaacccTCGTCTATAATCTTCAGAAGTCTAGCGAGTTCAATGACTACATCAGGCAACACTTCAAGATGCAGTGTCATGTGTGCAGTGCCCCCATGGAGGGTTTCTCTGAGATGCTGGTCCATGTGCGAGAGAAACACAATCAGCGTGGATACGCCGTCTGCTGTAACCGAAAGTTCAGAAAGCGCGGCGTACTGGTCGATCATCTGCGACGCCACGAGGATCCCGACCTCTTCAAGTGCAAAATCTGTGATCGCGTAATGGGCCAGAGGCGAAGCCTTGAACTCCACATGCGAATGCACGACGTGAAGTCGCAGGGCCGTCTCTACCAGTGCGATCATTGTTCCAAAAGCTTCTACAGCGCAGTCGTCTGCCAACGACACAAACTAACGCACATTCCCAAGGAGCAGTGCCAGGTGAAATGCACCAACTGCGAGAAGACTTTCCCCACCAAATATACCATGCAGCAGCATTTTAAGCTCGTACACTTGAATTTATATGCAAAGATTTGCGACGTTTGCGGCAAGTCCATACGTGGGCGGGAGGCTCTCGCTCGCCACATGGAGGAGCACACGGGCGCTCCGCAGGCTACCATCGAGTGTCATCTGTGCGACTCCAAATTAACCACCAAATACGGACTGGCGCGTCACATCAAAATGATGCACACTGTCGAGAACCTACAGCCGATGCAGTGCGAGCTGTGCCTCAAGATTTCACCCAGCCTCCAGGCCCATCAGCACCACATCAAGTACACCCACAACACGGCCCGCAATCACCAGTGTCCGATGTGTGAGAAGGCCTTCAAGCGACCAAACGAATTGCGGGAGCATTTGACAACGCATACGGGCGAAGTTCTGTACACCTGCCCGCATTGCACACAGACCTTCAACTCGAATGCCAACATGCATGCCCACCGCAAGAAAGTGCATCGCAAGGAGTGGGAAGAGCACCGCCTCCAGCGCTTGGTGCGAGGCCGGAAAAAAGATTCGATCATTGCAGCGAGCGTGCGAAAGACCACCGAGGCCAGGGAGGACTTCAGTGTAGATCAGACCACTGCTGTCGAGGCTCCAGCCGCCAACAGTCTCAGAGTCTTAGAGGAATGTTAA
Protein Sequence: MPCFLCTHRVDDAVSNIKFDSVEADSLGLRQIIEKHFWLRFNDSVDGYVCGSCWEQLLLFHNFYLTVENAHKALTELETKQAEENVAENQTTPTAVVAAVYGGTAKDENVQSVAAAVKRRRGRPRKTRAASSDEEFQNVLEQINLNEIKIEYPEADLTIADVLEDQEEQDFESRSGCATEVDDIEEPKPKITRKVRGRGRGRGRVRLAEKPKKTLVYNLQKSSEFNDYIRQHFKMQCHVCSAPMEGFSEMLVHVREKHNQRGYAVCCNRKFRKRGVLVDHLRRHEDPDLFKCKICDRVMGQRRSLELHMRMHDVKSQGRLYQCDHCSKSFYSAVVCQRHKLTHIPKEQCQVKCTNCEKTFPTKYTMQQHFKLVHLNLYAKICDVCGKSIRGREALARHMEEHTGAPQATIECHLCDSKLTTKYGLARHIKMMHTVENLQPMQCELCLKISPSLQAHQHHIKYTHNTARNHQCPMCEKAFKRPNELREHLTTHTGEVLYTCPHCTQTFNSNANMHAHRKKVHRKEWEEHRLQRLVRGRKKDSIIAASVRKTTEAREDFSVDQTTAVEAPAANSLRVLEEC*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00564172;
90% Identity: iTF_00564172;
80% Identity: -