Basic Information

Insect: Drosophila pseudoobscura
Gene Symbol: -
Assembly: GCA_009870125.2
Location: CM020869.1:9114459-9126118[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.42 32 5.4 1.8 1 23 695 717 695 717 0.96

2 7 1.7e-05 0.0013 19.3 1.1 1 23 723 745 723 745 0.98

3 7 7.2e-06 0.00055 20.4 0.2 1 23 751 773 751 773 0.98

4 7 3.4e-06 0.00026 21.4 1.4 1 23 779 801 779 801 0.98

5 7 0.00096 0.072 13.7 0.7 1 23 807 829 807 829 0.98

6 7 5e-06 0.00038 20.9 2.4 3 23 837 857 835 857 0.94

7 7 0.00023 0.017 15.7 3.4 1 23 863 886 863 886 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.42	32	5.4	1.8	1	23	695	717	695	717	0.96
2	7	1.7e-05	0.0013	19.3	1.1	1	23	723	745	723	745	0.98
3	7	7.2e-06	0.00055	20.4	0.2	1	23	751	773	751	773	0.98
4	7	3.4e-06	0.00026	21.4	1.4	1	23	779	801	779	801	0.98
5	7	0.00096	0.072	13.7	0.7	1	23	807	829	807	829	0.98
6	7	5e-06	0.00038	20.9	2.4	3	23	837	857	835	857	0.94
7	7	0.00023	0.017	15.7	3.4	1	23	863	886	863	886	0.98

Sequence Information

Coding Sequence: atgctgccgctgcaggagcaagtgcagcagcaaccgCCGCCACAACCCCAGACCTTTAATTGGCAACTGGAGGATTACGCCTACTTTCGAAAATGCGGAGAACTTACCACATCGCCGGATGTGCAGAGCTTTGGCTTCAATTGCGCCTTCTGCCCTGCAATTTGCTTGCAGTTCTCGGTGTTTATGGATCACATTCGCGGCCAGCATATTCAGGACGTAAGACGACGGTACGAGGACTCCGAGGATACAATCGAACAAGCAACTCAAACAGATTTAATGATAATGGAAATGGACTGCCATGACATATTCCAACTGGAAGACCAGGACCAGACCGCAACCGATAAATGCACGaagaaatcaaatttaaatggaatggagatggaaatgggaaCTGAGACGGAATCCACGATTGTGGCAGACACGCAACGCCTGGGGCTGATAGACATGGACATTCAGCTGATGAATATCGTCGCAGCGACCCCCACAATGCAACTATCCCATGCAGTAGGAGCACCCGAAATAGATTTGGTTTATGTTATGGAAAATCCATTGCCACCCTCACCGCCGCCATCCGCGGACATTTCGGGTGACGAGCAGACCTGCCTTCAGGCACTGGGTTCGTTTGAAGTGCTTCATGAAATAGTGGGCACGGTCACGTCTACGCCGACGCCCTCACCTTTGGCTGGGCCTGGTGTTGGGGTCGCCGCTCCACTTCAACCGCCGCGATACGAGACACGACGCGTGGCAATGCAGCGCAAGCTTCGTCAGGCGGAAAACCAGAATGCAAAAGATTCCAACCGGCAAGAATCAGAgccagaggcggaggcagaggcagaggcagtgacGGGAGCGGCAGATGCAGAACAGTTCTCCCCCGAAAACGTGTCGGAGCTAACACCGCCAGCGACGCCTCCAACCCCAGGGCCGCCCACGTCCCCCACGAGTAGCATTGGCAGCAACATGGACTTCCAGGCGCGCACTCGTCGCGAACTGGAACGAAATCGAGAATTCGTTGGCTCTCTGCTGGCGGCCTATGAACGCATGGAAAAGTTGTGGAATCCCCGGCATCCCGACTACAAGTACAATGCCAAGCGGAGTGTTTACGGAGAACTGGCTGCCCCACTGGAGGGCATCTGCCAGATGCAGCTGACGGGCGTCGAAATATTTGCCGTACTCAAGGAGCTGCGTGGCCGCTATCGCCGGGAGCTGAGCAAGCTAAATGCCCTCGGCGGGAAGTACAAATCCCGCCTGTGGTACTTTGACAAGATGCACTTCCTCAGAGGCGTCATCGAGAACAAGCGGGCCGAAAGGGAAGCCAAGATCAGCAATGATAGCACCGAAAGCGAAAAGTCATGCGAAACCGATGGCGAGTCCTGCAGCAAGTCTGCCCTGTATCGTGAGGTGCTCAGCTTCATACTGGATGCGTTCAAGCGGCTGGAGTGCTTGTGGAATCCCCAGCACTACGAGTATGCCAGCTGCTGCAAGAAGGAGCTGTACCGGGAGATCTCCGCCCAATTGCAAGAGGAGCTCAACTACGAGCTGAGCGGCGAGGAGTGCCACAAGGAGATACTGAAGCTGAGGACGCGCTATCGCAAGGAGCTGCGTATGGTGATCAAACACAAGGGACTGTATCTGCCCAAGCTCTGGTGCTACGACGAGATGGAGTTTCTGCATCCAATACTCCAGGAGCAGATCTTCAACAAGATCAGCAAGAAGGTCGGTGTGGTGGAGACCAACCAGAAGACGAAGTTCATCGATGCCAGCTCCATTGAATTCGGAAGGGCAGAGGATCAGCTGCAGTTTGTGGAGATCTATCGCAATTATGCGGCGTTGTGGGATGTGGATCATCCCGACTTTAGATCGAATGCCTACCGCAGTCAGGCGCTGGCCCAGATGTTGGACGAACTGAACACAACCTTCCATACGGCATATGCCGCGGAGCAACTGGAGAAGACTCTGTTCGAGCTGCGCAAGGAGTTTTCAGCGCAGAAACGGAAAATACTCACCAACCCAGGGGACTCGTGCAGCATTCCCCTGCTGCACGCAAGACTGGCGGACTTTTTGGAACAGAACCTGGGGCCTTTCCGATGTGACGTCTGCTCGGAGCTAATCAAGACCTGCGACCAGTATAAGGTGCATCGGTCCGGGCACGACGGCACCCCGCCCTTCATATGCACGCTCTGCGGCAAGGGCTTCCAGATGCCGTGCAATCTGACGGTGCACATTCGACGGCATCGGCGCGACTTTCCATATGCGTGCGAGAAGTGCGACAAACGCTTTGCCACCTCCACAGAGGTGGCCATCCACCTGCGGACGCACACTGGAGAGCGGCCCTACATCTGTGACCTGTGTGGGAAATCTTTCAAGACGTGGTCCTTCTTCGATATACATCGGCGCAGGCACCTTAACCAGTCGACATTCAGCTGCCCCATCTGTGCAAAGGGGTTCTACGAGAAGAATCGCTTCACCGACCACATGAACTCCCACTGGGCCATACGCAAGCACCTGTGCACGGTGTGTGGCAAGACCTTTACCACCTACGGCAATCTCAAGAAGCACACCGAATTGCATTTGGCCGTGAAGAAGTACAAGTGCTGCTCGTGCGGCAAACGATTCGCCCAGTTTGCCAGTCTGCGCTGGCACAAAAAGCGGGCACACGGCTCTGGGCAATCGGAGGAGAAGTAG
Protein Sequence: MLPLQEQVQQQPPPQPQTFNWQLEDYAYFRKCGELTTSPDVQSFGFNCAFCPAICLQFSVFMDHIRGQHIQDVRRRYEDSEDTIEQATQTDLMIMEMDCHDIFQLEDQDQTATDKCTKKSNLNGMEMEMGTETESTIVADTQRLGLIDMDIQLMNIVAATPTMQLSHAVGAPEIDLVYVMENPLPPSPPPSADISGDEQTCLQALGSFEVLHEIVGTVTSTPTPSPLAGPGVGVAAPLQPPRYETRRVAMQRKLRQAENQNAKDSNRQESEPEAEAEAEAVTGAADAEQFSPENVSELTPPATPPTPGPPTSPTSSIGSNMDFQARTRRELERNREFVGSLLAAYERMEKLWNPRHPDYKYNAKRSVYGELAAPLEGICQMQLTGVEIFAVLKELRGRYRRELSKLNALGGKYKSRLWYFDKMHFLRGVIENKRAEREAKISNDSTESEKSCETDGESCSKSALYREVLSFILDAFKRLECLWNPQHYEYASCCKKELYREISAQLQEELNYELSGEECHKEILKLRTRYRKELRMVIKHKGLYLPKLWCYDEMEFLHPILQEQIFNKISKKVGVVETNQKTKFIDASSIEFGRAEDQLQFVEIYRNYAALWDVDHPDFRSNAYRSQALAQMLDELNTTFHTAYAAEQLEKTLFELRKEFSAQKRKILTNPGDSCSIPLLHARLADFLEQNLGPFRCDVCSELIKTCDQYKVHRSGHDGTPPFICTLCGKGFQMPCNLTVHIRRHRRDFPYACEKCDKRFATSTEVAIHLRTHTGERPYICDLCGKSFKTWSFFDIHRRRHLNQSTFSCPICAKGFYEKNRFTDHMNSHWAIRKHLCTVCGKTFTTYGNLKKHTELHLAVKKYKCCSCGKRFAQFASLRWHKKRAHGSGQSEEK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00484618;
90% Identity: iTF_00517951;
80% Identity: -