Basic Information

Insect: Drosophila pseudoobscura
Gene Symbol: wdn
Assembly: GCA_009870125.2
Location: CM020868.1:3676798-3679571[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 3.4e-05 0.0026 18.3 0.8 1 23 299 321 299 321 0.99

2 7 0.057 4.3 8.1 1.8 2 23 332 352 331 352 0.93

3 7 6.2e-07 4.7e-05 23.8 1.1 1 23 358 380 358 380 0.99

4 7 3.9e-06 0.00029 21.3 4.0 1 23 386 408 386 408 0.98

5 7 0.0002 0.015 15.8 3.0 1 23 414 436 414 436 0.97

6 7 5e-06 0.00038 20.9 0.8 1 23 442 464 442 464 0.96

7 7 9.2e-05 0.007 16.9 2.3 1 23 470 493 470 493 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	3.4e-05	0.0026	18.3	0.8	1	23	299	321	299	321	0.99
2	7	0.057	4.3	8.1	1.8	2	23	332	352	331	352	0.93
3	7	6.2e-07	4.7e-05	23.8	1.1	1	23	358	380	358	380	0.99
4	7	3.9e-06	0.00029	21.3	4.0	1	23	386	408	386	408	0.98
5	7	0.0002	0.015	15.8	3.0	1	23	414	436	414	436	0.97
6	7	5e-06	0.00038	20.9	0.8	1	23	442	464	442	464	0.96
7	7	9.2e-05	0.007	16.9	2.3	1	23	470	493	470	493	0.98

Sequence Information

Coding Sequence: ATGGAGTGTAAAGGAAAAAGCAAGAGAATGAAAGAAGAGGCGCCAAGCAAGAAATTGCCGCCTAAAATTTATGGCGGGGACTGCACCCCCACCAAGGCGGCACACGACGAGATTCTCAGCTCCCTGCTGCGCATTAACAATTTCGATTCGATATCGAGCATCAAGGATGAGTCTCTGGATATTGATCTATCCGCCTGCGTGACCATCAGCTCCGCGAGCCTCGTCAACGGCAACAGCCTCTCGTCCACGGACTTTTGGCGCGTGCTCGACGAGAGCGCCCAGAACAACACGGAGCTCAATCTCTCCGCCGACGTGTGCCGCGATGACCTGGTGGCGGGGCCCAGCGCTAGCATCGTGGCCCGTGATCTATCCAGTGACAATCACAGCTCCGAGTTCAATGTGACTTTCCTGCGGCCAGAGCCGCCGAATGCCTTCACCAATTCCCCCTTCAAGAAGACTTCATCCTCGACCTGCACGACGCCGGTGAAGCTGTCGCCGGAACAGATGCACATGCAACTGATGCCCCAGCCGATGCAACGCAAGCCCAAGCTGCcggcggcaacggcagtgCGTCTGAAGGTCTTCAAGGAGGAGCCGCTCGAGGAGAGGCCGCTGCCAGAGCTCAAGCCACTCAATGTGGTCACCAAAGTGGAGGTCTGCGAGTCGGATTACATGCCGCCAGCCTTTACCATCTTCCAGCAGCCGAAGCCGGTGGCGACGACGTCCGGAGAAGCGACCAGCATGCCGCCGCCAATATCGACGGATGGCAATGCGAAACCCTTCGAAGTGGATCCTGTGCCACTTCACAAGTGCCTGGACTGCAAtggcctgctgctggagagTCCCGAGGAGTTGAGCAAGCATGAGGCGGCCGGCCATCGCCTGCGCATGACATACAAGTGCAACGAATGCCAGCGCGACTTTGAAATGCTCGCCGGCCTCAAGAAGCACCTCAAGACGCATCGCACCGAGGGACGGAAGGACACCTGGAAGAAGTGCCCCGACTGTGGCAAATGCCTCAAATTGGGAAGCATGTGGATGCACCGTAAGATTCACAGCGACAACAAGAAGTATCAATGCGATATTTGCGGCCAAAAGTTTGTGCAGAAGATCAATCTGACGCATCATGCACGGATACACTCATCGGAGAAGCCGTACGAGTGCCCAGAGTGTCAGAAACGCTTCCAGGAACGCTCCCATCTGCAGCGCCATCAGAAATACCATGCCCAAACGCGTTCCTATCGCTGCGAGAAGTGCGGCAAAATGTACAAAACCGAGCGCTGCCTCAAGGTGCACAATCTGGTGCACTTGGAGCAGCGTCCCTTCGCCTGCACCGTCTGCGACAAGAGCTTCATTAGCAACTCGAAGCTGAAGCAACACTCGAATATCCACACTGGGATGCGACCCTTCAAGTGCAACTACTGTCCGCGGGACTTTACCAACTTCCCCAACTGGCTGAAGCACACCCGTCGCCGCCACAAGGTGGACCACAAAACTGGCGAACACCTCGAGAACATTCCCTCGTATTGCTCGAAAAAGTCGACCACCAGCAAGGCACAgaaagccgccgccgccgccgcagcagctgcagcggcagcagcaacagccgcagcgAATGGGGATGGAGATCCTGGCGCCACAACGGATGGCAAAGCCAAGCCCagtcctgcagcagctgcgacGGCGCCAACGCCAGTGAAACAGGCTCGCAAAAagaagcagccacagcaggcCACCCTGGCCGCCTTGGGCATCACCTTGCCGGCGGGCACTGCACTCCAACAGGTGCACCCGGTGCCCTCAAAGGCCTCACAAGGATCCCAGCAGGAGCTGACCACTGTACTGGTGACATtgccccctccaccccccaaGCAAGCGAAGACCAAACGCGAACGCAAACAGCCGGCACccaagcagctgcagcagaagccacagacacagaagcAAGCCCAACTCCAGGCCCTGATGGAGCCCATCGCTTGTCCCACGCTGCCGCATATTAAGAAGGAACCAGTGCATCCGCAGGGCCCGTTCTTGGATCTGCACGGCCTCAGTCTCACATCGGCCGAAGAACTGATTATGGAGCAGGCCCTAGAAATGGAAGAGTGCGGACTGTATGATGCTCCCAATGCCAATACGGAAATGGGAACATCGGACAATGCCATCTCCGATTCGGCTGCAGCCCTGCACTTTCAGATCAAGAACGAGCTGCCCGACGAGCTCCTCCCAGATGAAGAATTTTTGCCTTGTAAGCCCAGCGATCGCCTAGCTTGCCCCTCACTCGAGTCGTCGCCGTTCTCTTCCCCTGCCTCCATGGAGCTGACTGCCGTCTCCTCCAACAATGGCAATTCGCATGCGGGACCGGTGCGATCTGGGAACTACTATCTGCCAGCCTTCACGCTAAATGCGCAGGGAAAGCTGAGCCACACGTCGCACAGCTCCCCCTCCTCGGGACTGTCGGTGAGTGGGACGACGAGTGTGTCGGCCGCCTCCACCACGGTGTCGATGGTGAAtgtgccgctgctggtgcgCTCGAATCAAATGTTGCCTTCGGTGGATACATTGCTCTTCACCACACAGACTGGCGGAAATCGGTTCTTTACCGGAAAGTCGGCGACCACGGCCACGTCCCATCTGACATGA
Protein Sequence: MECKGKSKRMKEEAPSKKLPPKIYGGDCTPTKAAHDEILSSLLRINNFDSISSIKDESLDIDLSACVTISSASLVNGNSLSSTDFWRVLDESAQNNTELNLSADVCRDDLVAGPSASIVARDLSSDNHSSEFNVTFLRPEPPNAFTNSPFKKTSSSTCTTPVKLSPEQMHMQLMPQPMQRKPKLPAATAVRLKVFKEEPLEERPLPELKPLNVVTKVEVCESDYMPPAFTIFQQPKPVATTSGEATSMPPPISTDGNAKPFEVDPVPLHKCLDCNGLLLESPEELSKHEAAGHRLRMTYKCNECQRDFEMLAGLKKHLKTHRTEGRKDTWKKCPDCGKCLKLGSMWMHRKIHSDNKKYQCDICGQKFVQKINLTHHARIHSSEKPYECPECQKRFQERSHLQRHQKYHAQTRSYRCEKCGKMYKTERCLKVHNLVHLEQRPFACTVCDKSFISNSKLKQHSNIHTGMRPFKCNYCPRDFTNFPNWLKHTRRRHKVDHKTGEHLENIPSYCSKKSTTSKAQKAAAAAAAAAAAAATAAANGDGDPGATTDGKAKPSPAAAATAPTPVKQARKKKQPQQATLAALGITLPAGTALQQVHPVPSKASQGSQQELTTVLVTLPPPPPKQAKTKRERKQPAPKQLQQKPQTQKQAQLQALMEPIACPTLPHIKKEPVHPQGPFLDLHGLSLTSAEELIMEQALEMEECGLYDAPNANTEMGTSDNAISDSAAALHFQIKNELPDELLPDEEFLPCKPSDRLACPSLESSPFSSPASMELTAVSSNNGNSHAGPVRSGNYYLPAFTLNAQGKLSHTSHSSPSSGLSVSGTTSVSAASTTVSMVNVPLLVRSNQMLPSVDTLLFTTQTGGNRFFTGKSATTATSHLT*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00565581;
90% Identity: iTF_00564160;
80% Identity: -