Basic Information

Insect: Drosophila pseudoobscura
Gene Symbol: -
Assembly: GCA_009870125.2
Location: CM020869.1:10624808-10628495[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.0089 0.67 10.7 1.3 2 23 348 370 347 370 0.96

2 17 2.5 1.9e+02 3.0 0.0 1 23 377 402 377 402 0.93

3 17 0.037 2.8 8.7 2.2 2 23 413 434 413 434 0.93

4 17 3.7 2.8e+02 2.4 0.5 3 23 475 496 474 496 0.92

5 17 0.015 1.2 9.9 0.2 3 23 504 524 502 524 0.92

6 17 0.00063 0.048 14.3 0.5 1 23 532 555 532 555 0.98

7 17 0.00079 0.06 14.0 0.2 2 23 560 581 559 581 0.97

8 17 2.9e-05 0.0022 18.5 1.0 1 23 629 653 629 653 0.92

9 17 0.038 2.9 8.7 1.1 1 21 658 678 658 679 0.93

10 17 0.017 1.3 9.8 0.6 1 23 698 723 698 723 0.96

11 17 0.81 61 4.5 1.9 2 23 741 763 740 763 0.94

12 17 0.0048 0.36 11.5 0.1 2 23 769 791 768 791 0.92

13 17 0.019 1.5 9.6 0.2 2 23 795 817 794 817 0.95

14 17 5.8e-05 0.0044 17.6 2.0 1 23 823 845 823 845 0.98

15 17 0.012 0.89 10.3 1.4 1 23 849 872 849 872 0.93

16 17 5.9e-05 0.0044 17.5 2.2 1 23 878 901 878 901 0.96

17 17 5.5e-06 0.00042 20.8 0.7 5 23 914 933 905 933 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.0089	0.67	10.7	1.3	2	23	348	370	347	370	0.96
2	17	2.5	1.9e+02	3.0	0.0	1	23	377	402	377	402	0.93
3	17	0.037	2.8	8.7	2.2	2	23	413	434	413	434	0.93
4	17	3.7	2.8e+02	2.4	0.5	3	23	475	496	474	496	0.92
5	17	0.015	1.2	9.9	0.2	3	23	504	524	502	524	0.92
6	17	0.00063	0.048	14.3	0.5	1	23	532	555	532	555	0.98
7	17	0.00079	0.06	14.0	0.2	2	23	560	581	559	581	0.97
8	17	2.9e-05	0.0022	18.5	1.0	1	23	629	653	629	653	0.92
9	17	0.038	2.9	8.7	1.1	1	21	658	678	658	679	0.93
10	17	0.017	1.3	9.8	0.6	1	23	698	723	698	723	0.96
11	17	0.81	61	4.5	1.9	2	23	741	763	740	763	0.94
12	17	0.0048	0.36	11.5	0.1	2	23	769	791	768	791	0.92
13	17	0.019	1.5	9.6	0.2	2	23	795	817	794	817	0.95
14	17	5.8e-05	0.0044	17.6	2.0	1	23	823	845	823	845	0.98
15	17	0.012	0.89	10.3	1.4	1	23	849	872	849	872	0.93
16	17	5.9e-05	0.0044	17.5	2.2	1	23	878	901	878	901	0.96
17	17	5.5e-06	0.00042	20.8	0.7	5	23	914	933	905	933	0.85

Sequence Information

Coding Sequence: ATGTcggaaaacccaaaaacaagcCGCAGCGGTCCTAGCTGCCTGCATTGCAGCGCATTCGGGGCCAAATTGAAGTACCAGGAGATATTTGATGAATTTGGCCTGGAACTGGGACTCCAAGAGCTGCTGGCGAAGCACTTCAGCTTAGATGTGACACCCAACGCTAATCAGCAACAGCTCCTTTGCGATGAGTGCGTGAATGTTCTGATCCGATTGTTTGACATTGACGAGCTACAGAAAGAACAGGATGCTGCGATTGCCAGACGAAAGAGCGCTGTCGAGGATGCACCTGCCCCAAAGAGCGCACCCAAGACGCCTCCAAATGCTGCAAGGAGTGCTTCCAAGACGGCTCCAAGCGCTGCAACGAGTGCATCCCACACGCCTCCAAATACTGCACAGCCTGTCAAGCCTACGGCTAAGAAGGCCGTACTGCCGGAGCCCCAGACTAAAGTGGAAAAGCCTGTGCCGGTGATACAGCCGGACCCGAAACCCAGCCGTcgtataattaaaaatgtatccGTGCCACTGCCATCTGCGGCCTCTGTAGCAGACGAAGTTGATAAAGTCAAGGCACCATCCAAGACTAAGCATGCTCCGAAGGAGGCAGACCAGGAGCAGATTAGTGCCCTCATTCTCAATATTCTAAACGAGGACGAGCCGGGCGTGGTAGATGAGTCAGAAACAGTTCTTCCCGACTCTTCCCAAACAACAATTGCAGTGCCAGAGAAGGAAGcggaggctgaggctgaagctgaGGTGACTGAAGAAGAAGATCTAGATGGGATGAATATCATATACGAGCATGAAGATATTTCAATTGAAGAGGAGGTAAATACCAAGCCAGACATCCGTCCATCCAGACTAAAAAGGCAGAAAacggagagccagagcgaggCAGACAACGAGGAGAGCGAGGCCAGCAATATAGTCCTCTTTAACTTTGTCGAGATCAAAGAAAAGGATGACATTGACGACTTATACGAGTACTTAGCCACGGTGGTGAGGACCAGCTTTGAGAAGCTAAAGTTCAACTGGAATACTGTCTGCCAACATTGCACATTAAAGTCCACTAGCTACGAGAACCTGCTGGAGCACATGCTGAGGGTGCACAAGTCCCGGTCGGATGTCTTTCGGTGCCCAATCGAGGGCTGCAGCTTGGAGCTAAAAGGACGCAAACTTCTGGCCATGCATTTGGTTGTTCTACATGCGCCTGTGGCTGAtaTTGCCATTTACGGCAGCTGTCCGGAATGCAAGATGACTTTCTCAAATAttttacaatacaataaacaTTCGTGTGCGCATATCATCAAGAAAAAACGGGGCGTTCGCTTGTTTTGCGAAATGTGCGCCCTGGAGTTTCCCTCCTGGAAGCGCTTCAATTTTCACAATCAATTCCATTTGGAGAAGCACCGACCGCGCGCTTGCTTTGTCTGTGGCTATGAGAACACCAACATCGACGAGCTCTTCCAGCATTTGCATTATTCCCACGAGCCAGAGGGCACTCTCTTCTGTGATCTTTGCGATCGCACGTTCCGGGATCCCGCTGTCTTCATAGAGCACAACACGTCGCACGCGACTGTGGGCAACGCCACCTACACCTGCGGCGAATGCCTGGCTACCTTCGAGACGCGTGGCAAACTGAACAGCCACACAAGATCAATGCATGGCAACGTCATCAGCTGTGAACTCTGCTCCCGCGAGTTTGCCTCTGAGGCCACGTACAACGTCCACATGAAGTCCCATTTGATTATCGAACGTTCCGTTCATGTCTGCGGGAATTGTGGCCAACTGAGCGAGAATCAGGAGAAAATGGACGCTCACTGTGGGAGCGAGGGCTCTGCCTGCTTTGGGGCGGAGAGGTACGTGGAACTGCTTCGCGATGCCTATGTCTGTGAATACTGCACCACGTACTTTAAGCAGAAGTCAGACTTACAGTCCCATCGCGAGACTGGTGTTCACGACAATGGCGTTTTTTCGTGTCAGCCTTGCGGAAAGGATTTTACCGACATGAAATTGTATCGTCACCATTGGCGCAACTATCAACAACTGCGTGTAGATGTTGCTCATCGGAAGCTGGACATTTGCACCTTCTTCATGTGCGACCAGAAGGACTGCTCGGCGGCATATGCGAACTGGAACTCACTCTACACGCACAAGCGACGCACTCACGATGAGTCTAAAGAGCGGCAGGAGAAATCGGCCAAGCCGCTGCAGGAATGGCAATGCCAATTCTGTCTTAAGCTATGCCGATCGAAAATGTCCTTATCCGTCCATGTCGCCCGGAGCCACAATAATGACAATGTGGTCTGTTCACTGTGCAACGCCTCGTACAAGAGCAAGGATGCCCTGGATAAACACTATGCTTACTGGCACGAGCCCATCGAGTGTCCGCAGTGCTTCAAGATTGTCAAGAACAGGCGTAACTACGACACCCACGTGAATGTGGTGCACTCAAACAAAAAGCGCTACACCTGCAGTGTGTGCGAGAAAGGCTTCTACCACAAGAGCGAGATGGAGGCTCACAAGAGGCTCCATTCCCAGTCGTACAGTTGCGAGCAGTGCAGCTTCACCACCAGGAACAAAAAGTCACTGTCTGTTCATACCCTGGGCCAGCACTTTAAGCGATTCGCCTTCGACTGCAAGATGTGCGACAAGCACTTTGGTCGACGCCAAGGACTGACCAACCACATACAACGTGTGCACGCCTCCAAGCATGTGTGCCGTAACTACATTGACGACGGCTGCGGCCGTTCGTTTACCACCAGTTCCCAGCTGAACGTGCATTTGCGCAAGGTGCACAACTCCACTTTAGTAGCCGACGATGTGCTCGAGGAGGAGGCGTATGCCATCGCCAGGCCGCCGGCAGCGAAGAAACGTTGCTTTGaggaggaggaggaagtaGAGCATGAGGAAGTAGAGCatgaggaagaggaggatATGGAGCAGGAGGATGAAGAATGTGCGCTGGAATTTGCCGAGGATGAGGCAGAGGGGGAACCAAAGCCGAACCGTGGCTCAAACAGAAAACATGGAAGAAAACTCCGTTCGGATGATTAG
Protein Sequence: MSENPKTSRSGPSCLHCSAFGAKLKYQEIFDEFGLELGLQELLAKHFSLDVTPNANQQQLLCDECVNVLIRLFDIDELQKEQDAAIARRKSAVEDAPAPKSAPKTPPNAARSASKTAPSAATSASHTPPNTAQPVKPTAKKAVLPEPQTKVEKPVPVIQPDPKPSRRIIKNVSVPLPSAASVADEVDKVKAPSKTKHAPKEADQEQISALILNILNEDEPGVVDESETVLPDSSQTTIAVPEKEAEAEAEAEVTEEEDLDGMNIIYEHEDISIEEEVNTKPDIRPSRLKRQKTESQSEADNEESEASNIVLFNFVEIKEKDDIDDLYEYLATVVRTSFEKLKFNWNTVCQHCTLKSTSYENLLEHMLRVHKSRSDVFRCPIEGCSLELKGRKLLAMHLVVLHAPVADIAIYGSCPECKMTFSNILQYNKHSCAHIIKKKRGVRLFCEMCALEFPSWKRFNFHNQFHLEKHRPRACFVCGYENTNIDELFQHLHYSHEPEGTLFCDLCDRTFRDPAVFIEHNTSHATVGNATYTCGECLATFETRGKLNSHTRSMHGNVISCELCSREFASEATYNVHMKSHLIIERSVHVCGNCGQLSENQEKMDAHCGSEGSACFGAERYVELLRDAYVCEYCTTYFKQKSDLQSHRETGVHDNGVFSCQPCGKDFTDMKLYRHHWRNYQQLRVDVAHRKLDICTFFMCDQKDCSAAYANWNSLYTHKRRTHDESKERQEKSAKPLQEWQCQFCLKLCRSKMSLSVHVARSHNNDNVVCSLCNASYKSKDALDKHYAYWHEPIECPQCFKIVKNRRNYDTHVNVVHSNKKRYTCSVCEKGFYHKSEMEAHKRLHSQSYSCEQCSFTTRNKKSLSVHTLGQHFKRFAFDCKMCDKHFGRRQGLTNHIQRVHASKHVCRNYIDDGCGRSFTTSSQLNVHLRKVHNSTLVADDVLEEEAYAIARPPAAKKRCFEEEEEVEHEEVEHEEEEDMEQEDEECALEFAEDEAEGEPKPNRGSNRKHGRKLRSDD*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00580943;
90% Identity: iTF_00580943;
80% Identity: -