Basic Information

Insect: Drosophila pruinosa
Gene Symbol: -
Assembly: GCA_018150935.1
Location: JAECWR010000199.1:15507984-15511659[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.6 1.3e+02 3.4 7.8 2 23 350 372 349 372 0.96

2 18 2.2 1.8e+02 2.9 1.1 1 23 379 404 379 404 0.91

3 18 0.0038 0.31 11.6 1.3 2 23 415 436 415 436 0.93

4 18 5 4.1e+02 1.8 3.0 2 17 447 462 446 473 0.75

5 18 0.23 19 6.0 0.3 3 23 506 526 504 526 0.89

6 18 0.0016 0.13 12.8 0.2 1 23 534 557 534 557 0.96

7 18 0.0005 0.041 14.4 0.3 2 23 562 583 561 583 0.97

8 18 2.7 2.2e+02 2.6 0.2 1 20 591 610 591 612 0.87

9 18 0.001 0.084 13.4 0.7 1 22 631 652 631 655 0.90

10 18 0.096 7.8 7.2 0.5 3 21 662 680 662 681 0.90

11 18 0.36 30 5.4 2.3 1 23 700 725 700 725 0.95

12 18 0.01 0.84 10.3 1.4 2 23 740 762 739 762 0.93

13 18 0.016 1.3 9.6 0.4 3 23 769 790 767 790 0.92

14 18 1.2 96 3.8 0.4 2 23 794 816 793 816 0.93

15 18 1.5e-05 0.0012 19.2 2.1 1 23 822 844 822 844 0.98

16 18 0.011 0.94 10.1 1.1 1 23 848 871 848 871 0.93

17 18 0.00015 0.012 16.0 3.0 1 23 877 900 877 900 0.97

18 18 0.001 0.084 13.4 0.2 5 23 913 932 905 932 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.6	1.3e+02	3.4	7.8	2	23	350	372	349	372	0.96
2	18	2.2	1.8e+02	2.9	1.1	1	23	379	404	379	404	0.91
3	18	0.0038	0.31	11.6	1.3	2	23	415	436	415	436	0.93
4	18	5	4.1e+02	1.8	3.0	2	17	447	462	446	473	0.75
5	18	0.23	19	6.0	0.3	3	23	506	526	504	526	0.89
6	18	0.0016	0.13	12.8	0.2	1	23	534	557	534	557	0.96
7	18	0.0005	0.041	14.4	0.3	2	23	562	583	561	583	0.97
8	18	2.7	2.2e+02	2.6	0.2	1	20	591	610	591	612	0.87
9	18	0.001	0.084	13.4	0.7	1	22	631	652	631	655	0.90
10	18	0.096	7.8	7.2	0.5	3	21	662	680	662	681	0.90
11	18	0.36	30	5.4	2.3	1	23	700	725	700	725	0.95
12	18	0.01	0.84	10.3	1.4	2	23	740	762	739	762	0.93
13	18	0.016	1.3	9.6	0.4	3	23	769	790	767	790	0.92
14	18	1.2	96	3.8	0.4	2	23	794	816	793	816	0.93
15	18	1.5e-05	0.0012	19.2	2.1	1	23	822	844	822	844	0.98
16	18	0.011	0.94	10.1	1.1	1	23	848	871	848	871	0.93
17	18	0.00015	0.012	16.0	3.0	1	23	877	900	877	900	0.97
18	18	0.001	0.084	13.4	0.2	5	23	913	932	905	932	0.90

Sequence Information

Coding Sequence: ATGTCGGAAAATTTGAAAGCAAAAGGCGAAACTGGGCCTAGCTGCCTGCATTGCAGAGTGCACAATTCAAAACAGCCATTCCAGGAGATATTCGATGAAGTGGGCATTGAAATCGAGCTGCCCGATTTAATTGCCAAGTATTTTCAACTAAATGTCAAACCCGATCCGCAAAAGCAGCAATTACTCTGCCAAGAGTGCGTCAGTACACTCATACGCTTCTTTGATATTGATGAACTGCAGCGTGAACAGGATGCGGCAAATGCTGGCAAGAACAAGCCAAGTACGCTGGCCAAGGCGAAGGCAACGACTCCAACAGCATCTCCGGTCAAACCAAATAAAGACGAAGCGAAGCCTGCAAAAAAACAGACGCCACCATCAGCCAAAACAAAAACTGAACACAAAAAACTGACAGATGCTGTAAAGTTGCCGCCAAAGTCTAAGCCACCAGTGGTTGCTGCTCCACGGTCGGAAGAGTCAGTGTCTATACGCATCACCAAAAGAAAAACATTGACGGTGACTCCAAAACGTATTGAAATCAAGGCGGAGCCTAAAGCCAACAAAGCAACCAGTGGCACGCCAGGTAATAAGCGAGTCAGCACTAAGGATGCCAGTTCAGGTGACCAGGAGCAGATCAGTGCACTACTACGTGATATACTCGATGATGAGAAAGCGCCACCCGATGACAAGTTTGCCGAGGCAGCAGCAACAGTGCGCCAACTGGAAGAAATTAAACAATTGGAGGAGGAGGAGGAGGTAGCTGCCGAGGAGCAAATACTTAAAGAACAAGAAAATACAGATGAGCTAGAGTTTCTGCTTGAAGCAGCTGACTCCTCGGATATGGAAGTGCCGCATTTCAAGACGGAGAAGCAGTCATCACATGAAGGGACGCAATCGCAAAATGAAAGCCAAAGCGAGGACGAATCCCTCAAAGTGGAGCCGTTCAACTTTGTGTTGATCAAAGAATCTGACGATATTGGAGATCTCTATGAGTATCTAACAACGGTGGTAAAGACCTGCTTTGAGACATTGTGCTTCGAATGGGCCACCGTCTGCCAGCATTGTTCGCTGAAGTGCACCAAATTTGAGAGTCTGCTAAGCCACATGCTAAAGTGTCATCAGCTGCCAGAGCAGCAGTTCAAGTGTCCCATTGAGGGCTGTCACAGAAAATTGCATGGCCGCAAATTTCTGGCCATGCATTTGGTGGTGTTGCACGCGCCTGTGGCAGAAATCCCCATTTACGGCAGTTGCCCGGAGTGCGGCATGACGTTCTCAAATATACTGCAGTACAACAAGCACTCCTGCGCCCATGTCATCAAGAAGCGTCGTGGCATACGCTTGTATTGTGAAATGTGCGGCTTGGAGTTTCCCTCGTGGAAGCGCTTCAACTTTCACAATCAGTTCCATTTGGAGCGGCATAGGCCACGCGCTTGCTTTGTGTGCGACTATGCGGACAACAACATCGACGATCTCTTCCAGCATTTGCACTACTCACACGAGCCCGAGGGCACGCTCTTTTGCGATCTCTGTGATCGCAATTTCCGCGATGCCGAAATCTTTGCGGACCACAATAAATCCCATGCGAATGTCACCAGCACTACTTATAGCTGCAGCGAATGCAGCGCCAACTTTGAGACACGCGGTCGCCTCAATGGCCACATGCGTGCCATACATGGCACTGTCATTAGCTGTGAGCTATGCAGTCGCGAGTTTGCCACGGAGGCCACCTACAACATACACATGAAGAAGCACCTGATCATTGAGCGCGAGGTGCATGTGTGCAACAATTGCGGGCTGCTCAGCGAGAACCACTCAAAAATGGTGGCACATGTTGAAAATGAGGATTCTGCTTGCTTTGGCGTCGAGATCTATGTGGAGCTGCTGCGAGATGCCTATGTGTGTGAATATTGCTCATCGTACTTCAAACAGAAGACGGATTTGCGTGCCCATCGTGATTCGGGCGTGCACAAGGACGGCCTATTCTGGTGTCAGCCGTGTGGCAAGGAGTTTGGCGACATGAAACTGTATCGCCATCATATGCGCAACTATCAGCAACAGCGCGCCGATGTCGCGCATCGTAAACTAGAGATTTGCCTGTACTTTATGTGTGACTATGAGGATTGTTGTGAGTCGTACATCAATTGGAATTCACTGTACACCCACAAGCGGCGCACACACGATGCGGCCGAGAAGCTGGATGCCAAGCCAAAGAATGAGTGGATTTGTCAGTTCTGTCAGAAGGTTTGCCGCTCCAAAATGTCGCTATCAGTGCATGTGGCACGTAGCCACAATAATAATAACGTTATTTGCAAGCTGTGCAAGGCATCGTACAAGGATGATGAGGCGCTTAGGAGGCATCATGCCTACTGGCACGAGCCCATGGAGTGTGCGTTGTGCATGAAATTGGTGAAGAATCGTCGCAACTTCGATACGCACATGAATGTGGTGCACTCGAATAACAAGCGCTATACCTGCAGTGTCTGCGACAAGGGATTCTATCACAAGAGCGAAATGGAGGCACACAAACGGCTGCATAACCAATCTTTTAGCTGCGAGCAGTGCAGCTTCACCACGAAGAACAAGAAGTCGCTGTCGGTTCATGTGCTTGGTCAGCACTACAAGCGCTTTGCCTTCGAGTGCAAGCTGTGCCATAAGCGCTTTGGTCGTCGCCAGGGCTTAACCAATCATGTGCAGCGATTGCATGCCTCCAAGAGCACATGTCGTGATTTCATTGAAGGCGGTTGCAACAAATCCTTCAGCACAACAGCACAGCTAAGTGTTCATGCGCGTAAAGTGCATAACACCAGGATTAGTGTGACGGAGGACGTGGACGATGAGCCAGAGACACAGGAGCCGGAGGAGGAGGAGGAGGAACAACAGGAGCACCAAGCTCAGCTAAAACGCAAAGCAAAACAAAATGATCCCACAGCCGCTAAAAAGCGCCTCATACGCCTTAGCAATGACACCCAGATTGAGTTTATTAACGCCGAAGCCGAGGAGGACCAGAAGAGCGTTACGGACTCGGAAATCATTGAGGAGATCCAAGAGAGCAAATCGAAAGTGCCGCCGTTGTTAAAAAGAAAGAAGAGACAAAGTTAA
Protein Sequence: MSENLKAKGETGPSCLHCRVHNSKQPFQEIFDEVGIEIELPDLIAKYFQLNVKPDPQKQQLLCQECVSTLIRFFDIDELQREQDAANAGKNKPSTLAKAKATTPTASPVKPNKDEAKPAKKQTPPSAKTKTEHKKLTDAVKLPPKSKPPVVAAPRSEESVSIRITKRKTLTVTPKRIEIKAEPKANKATSGTPGNKRVSTKDASSGDQEQISALLRDILDDEKAPPDDKFAEAAATVRQLEEIKQLEEEEEVAAEEQILKEQENTDELEFLLEAADSSDMEVPHFKTEKQSSHEGTQSQNESQSEDESLKVEPFNFVLIKESDDIGDLYEYLTTVVKTCFETLCFEWATVCQHCSLKCTKFESLLSHMLKCHQLPEQQFKCPIEGCHRKLHGRKFLAMHLVVLHAPVAEIPIYGSCPECGMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCDYADNNIDDLFQHLHYSHEPEGTLFCDLCDRNFRDAEIFADHNKSHANVTSTTYSCSECSANFETRGRLNGHMRAIHGTVISCELCSREFATEATYNIHMKKHLIIEREVHVCNNCGLLSENHSKMVAHVENEDSACFGVEIYVELLRDAYVCEYCSSYFKQKTDLRAHRDSGVHKDGLFWCQPCGKEFGDMKLYRHHMRNYQQQRADVAHRKLEICLYFMCDYEDCCESYINWNSLYTHKRRTHDAAEKLDAKPKNEWICQFCQKVCRSKMSLSVHVARSHNNNNVICKLCKASYKDDEALRRHHAYWHEPMECALCMKLVKNRRNFDTHMNVVHSNNKRYTCSVCDKGFYHKSEMEAHKRLHNQSFSCEQCSFTTKNKKSLSVHVLGQHYKRFAFECKLCHKRFGRRQGLTNHVQRLHASKSTCRDFIEGGCNKSFSTTAQLSVHARKVHNTRISVTEDVDDEPETQEPEEEEEEQQEHQAQLKRKAKQNDPTAAKKRLIRLSNDTQIEFINAEAEEDQKSVTDSEIIEEIQESKSKVPPLLKRKKRQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -