Dpru008597.1
Basic Information
- Insect
- Drosophila pruinosa
- Gene Symbol
- -
- Assembly
- GCA_018150935.1
- Location
- JAECWR010000199.1:45361246-45366094[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0021 0.17 12.4 0.3 1 23 138 160 138 160 0.98 2 15 0.75 61 4.4 3.3 1 23 166 189 166 189 0.96 3 15 3.7e-05 0.003 18.0 2.5 1 23 388 410 388 410 0.98 4 15 1.6 1.3e+02 3.3 2.4 1 23 416 439 416 439 0.93 5 15 0.38 31 5.3 0.6 1 23 464 487 464 487 0.92 6 15 0.001 0.085 13.4 1.9 3 23 772 792 771 792 0.92 7 15 0.077 6.3 7.5 1.7 1 23 798 821 798 821 0.98 8 15 1.2 95 3.8 1.1 3 23 859 879 857 880 0.92 9 15 0.011 0.86 10.2 0.5 1 23 901 924 901 924 0.97 10 15 0.018 1.5 9.5 0.8 1 23 1138 1161 1138 1161 0.91 11 15 0.00013 0.01 16.3 4.4 1 23 1174 1196 1174 1196 0.98 12 15 9.1e-05 0.0075 16.7 0.4 2 23 1202 1224 1201 1224 0.93 13 15 0.002 0.16 12.5 3.7 2 23 1233 1257 1232 1257 0.91 14 15 3.5e-05 0.0029 18.0 0.2 1 23 1262 1284 1262 1284 0.99 15 15 0.018 1.5 9.5 1.2 1 23 1290 1313 1290 1313 0.96
Sequence Information
- Coding Sequence
- ATGGCGCGCAAGCGAATAAAAACAGATGACATGGAAGTGAATTTTAAGTTTTTGTGTCGCTGTTGCCTGAAGTCCGAGGCAGAGTTTTTCAAGCTGGACTCCCTCACCGAAAATATTTTTGGCGAGCCGTCCCAAAAAATACCTCTCATGCGCTTGCTATTATACTGCTTGCGTACTGAAAATCTGCCCGAGCTGCCGCAATATATTTGCGTGGAATGCAGCAAGAGTTTGCAAATTGCCTACTCTTTTATACAAAACGGTCTCAAGGCGCATGAAATTCTGTGTCGCAAACTATGCCCTGGCAATATAAAAACTCAACTCAGATGCAATGGTCAACAATTCTTTGAGTTGAACCAAGATGACTCAAAAGTATGCATAGCCAATGCGAAGCCCACAAAGACGCCCGTGCGCCACGAATGCAAAATATGTGGCGCGATTATCTATAATCGTCTGGAACTTAAGGAACACATTCGAATGCACACAGAGGAGTCGAGGCATTCATGCAAGCTGTGCAAATTCGTGACTACTAAACAACAACAGTTGCCGGAACATTATAGAAAAGAACATGGCTTGACGTCTGACCAATTTAATCAATATCTTAAAATCAGAGCGTCCCTGCAGTCTGTTTCTACAAATGCGACGACTTCCACAGAATTTGAAAATGATGGTCATGACAAGGTGTGTACACTTGAAGACATGGAGCTGCTGATACCTACTGTTCTGACGCCGGAAGACTTTTCACAACCTCAACTTGTCACCAATCAACTACGTGATATTGAACAACAATTGTCTAACTCATTGGCTATTGGTCAGTCTGATACTGGTGTGAGTGCCGTAGTCGTGTCGTCCGATTCGACGATAGCGCCGAGCGGAAGTACCAATGTCAGTATAGGTGCAGAGTTTCTGGTCATGCCCGATGGTTCCTTGCAGCAAGTCCATGATGGCGGAGTTGTTTTTGAGTATATCGATGACTGCAAAAGCACGGTCACAACGTCATCTACCAATGTAAGTCTTCAGAACTTATTGGATGACTCCAAGCCAGATGTCACTTACAATTCAATGGACATGGATACGAACCACTTGGTTGTTGGAGACAGGTTGCCTCAAATAACTGTAAAGCCAAAACTTAGATCAGGGCCAGGATCAATTGGAGTTCTGAAGCACAAGTGTAATCTCTGCCCCAAAACTTTCCCCACAATTTCACGCCTTAAATCTCATCAATTGACACATAGTCATTTGCCCAAGTTCTACTGTGATCAGTGCTCTTACCACTCGCTGCGTAGTTCTGATCTTATCCAACACTATACAAATGAGCATAAGACCTCTATTGGCGATAGTAAAAGTCAGTTTGAAAGATCATTACAATCACAGACGGACATGAGTCGAATATACTCTTGCGACATGTGTTTATTTGATACACCGAGCAGTGCCCAGCTAAAATCACACTACAGTGATAAGCATTATATTCAGCCAAATGAGGTACAGCTGCGTCCTAGCTGGACCAATGACTCCAAGGATAAGGATGGCCGTTCATCACAAGCTAGTGGAAGTGGTTCAAGTCAGCTGTCACAGCCAGTGATGCCGCGTATTCCATTGGGTATTACATATCCATCAACGACGGCGGTGGCAGCAGTTGAAACAACAGCGACAACTTCAAACACACCAGTACAGCTACATCCACCACAGCCTACAACAACAGCTGTGGTTACGCCTGCTGGTGAAATAAATGTGGTCGTGGACGCAACTTCGTTGTTCTATGCAGCAGGTGCAACTCCATCTGACGGAGTGGCAACAACAACAACTGACATATCTGTAGCTGAATCAAATGATTTTGCAATTTTTTCAAAACAATCTTTAACCAATAGCATAAGAGAATCATCTATAACAGGAGAGTCAAGTGGAAGGTTGCCTGCTGTTAGTGTTTCTTCTGCTGCTACTAGTAATTTTGTTGTGAGTTCCACAGTAAATTCAAACACCAGCATATTTGGGGACATGCAAGATTTTATTGATAATACCGATGTGGCAGCCATATGCACCATACCCGCCGACGATATGCCTGTCGTCGACGGTGATGATATTGTTATTGATAACAATAATATGAGCTTGGACTTTGATGCTGAGAATCTATTTGACGACTTTGAGGAAGATGTTGAAGTTGGAGAAGATGATGACGAGGATGAAGATGATCCGGAAAATGAAGATGAGAATGATAATAATGATGCGGCTGCCGATCAGAATTTGTTGCTCACCAGCGATGATGATGACGTCGATGACTTTGACGACGAGCAATCAAAGCATCTACAGAAACCATATTGTATATACTGTAACAAAAAGTTTACAAGCCAATACAAGTTCGAGAATCACATGTTCGTACATCGCGGACTTGCACCATATCGATGTGAACTTTGCACGAACCTGTATAACATGAAACGTCTGTTATTACGGCATTACAAAACAGTACATAAACGTATGCCCACTCGTGACATGGTTCAAGCAAAGGGTGACAAAGTATCTGTGGAGCGTACAACAGTTGAAAAATTGCACGTCAATGTTGAAAAGCCTCCCATGGTGATGTGTGCTAAGTGCCCTTTTGAATGCGAAGAGGAAGAAGAGATGCGAAGGCATCTGAATGCGCACCATGGCATTAACGACGGCGTTTCTATACATGCTAACGAGGTGTTTATCATTCGAAAACTACCTTTTGAATGTCCACGATGCATTCGTACATTTGCGGCCAAGCGCACGCTGGTTCGTCATTTGCAACGGAGTCATTTAGTAGACACAATCATCGAGATGCAGGCGCCTCAACTAACAACTAGCTCATCGGCAACAACAACCACAACTACGGCTACCACCGCCTTGCCGAAGAATGCCGAAGAGGGATATGGCGGCAATAGAGCTTTTGAGCAGCGTGTCGTTGATGACGATCAACGCGACGGCGATGGCAATGGAAAATGCGACGATATCGTGATAAACAGTGACACAGGAATTGAAACGGATAATGAAGATTTAGACACAAAATCATTAGTCCCAACATCAACGTCAATAAATACCATAACAGCCGATACGAAAGATGTTAATGTAACTGATAAAACATCTACAGAATCCTCCTCCCCTGTAACTACTTCAATGTTAGAATCACCGACATCATCGTTAACAACATTAGCAGCAACCTCATCTAATCTAACAGTACTAGACAAAACACCAACAACCACAACTTCAACACCGAATCCGTTTGATTTTGATCTGGATTTCATTGGAAATGACACTCCACTTAAAAGTAATAATGACAGTTTTAATATTATGCCCAGTACACGTCAATTGTTAAATAGCTCCGACAAGTTATTGACGGCTGCATTGGAGCCATCACCAATTAAGGACCTACGTTCAAGGTTCCCTCGAACACCAATTTTTGTATGCAAGCAATGTAACCAAACATTTGACGAGCTGACTAAACTGTCGCAACACGAATTGGAACAACATTCCAGCAACACTGTACAGCCGAACAACATCTACCAGCATCAGTGCAAAGTGTGCAACACCACATTTCGGACAATAACGTTACTTAATTATCATATGAAAAGGCATGCACCTAGCAAAGTTCAGTGCAAATTATGTTCCAAGGAGTTTACATCTAATTCGGACTTGGAGCAGCATGAGGACTCGGAGCATTGGCACCTTAAAAATAGGCCCTTAAAATGCAGCATCGATGGTTGTGTCAAGACTTTCAATTACAAGCATCATCTAAAACGTCACCAAACAGCGTCGCATATGCGTGTTGATTATACATGTCCAGAGTGCGGACGCTATATGGCAACCAGTCAACAATTAAGAAATCACATAAGAATTCACAAGGGCACATATTCCTACAAGTGTCCCAAGTGCGCTCGCACGTATATGCGAACTAACCCTTTTAAAAGACACGCGCTGCGTGAACACAAATGGCATCTTACAGATGATGAAGCTAAGAAAATGTGTATCGCAGTTGAGACGAAGAAAATACGTGAACGAAGGTCCCTTAATATTGAAAATGAACATTCGGATTAA
- Protein Sequence
- MARKRIKTDDMEVNFKFLCRCCLKSEAEFFKLDSLTENIFGEPSQKIPLMRLLLYCLRTENLPELPQYICVECSKSLQIAYSFIQNGLKAHEILCRKLCPGNIKTQLRCNGQQFFELNQDDSKVCIANAKPTKTPVRHECKICGAIIYNRLELKEHIRMHTEESRHSCKLCKFVTTKQQQLPEHYRKEHGLTSDQFNQYLKIRASLQSVSTNATTSTEFENDGHDKVCTLEDMELLIPTVLTPEDFSQPQLVTNQLRDIEQQLSNSLAIGQSDTGVSAVVVSSDSTIAPSGSTNVSIGAEFLVMPDGSLQQVHDGGVVFEYIDDCKSTVTTSSTNVSLQNLLDDSKPDVTYNSMDMDTNHLVVGDRLPQITVKPKLRSGPGSIGVLKHKCNLCPKTFPTISRLKSHQLTHSHLPKFYCDQCSYHSLRSSDLIQHYTNEHKTSIGDSKSQFERSLQSQTDMSRIYSCDMCLFDTPSSAQLKSHYSDKHYIQPNEVQLRPSWTNDSKDKDGRSSQASGSGSSQLSQPVMPRIPLGITYPSTTAVAAVETTATTSNTPVQLHPPQPTTTAVVTPAGEINVVVDATSLFYAAGATPSDGVATTTTDISVAESNDFAIFSKQSLTNSIRESSITGESSGRLPAVSVSSAATSNFVVSSTVNSNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNMSLDFDAENLFDDFEEDVEVGEDDDEDEDDPENEDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLLRHYKTVHKRMPTRDMVQAKGDKVSVERTTVEKLHVNVEKPPMVMCAKCPFECEEEEEMRRHLNAHHGINDGVSIHANEVFIIRKLPFECPRCIRTFAAKRTLVRHLQRSHLVDTIIEMQAPQLTTSSSATTTTTTATTALPKNAEEGYGGNRAFEQRVVDDDQRDGDGNGKCDDIVINSDTGIETDNEDLDTKSLVPTSTSINTITADTKDVNVTDKTSTESSSPVTTSMLESPTSSLTTLAATSSNLTVLDKTPTTTTSTPNPFDFDLDFIGNDTPLKSNNDSFNIMPSTRQLLNSSDKLLTAALEPSPIKDLRSRFPRTPIFVCKQCNQTFDELTKLSQHELEQHSSNTVQPNNIYQHQCKVCNTTFRTITLLNYHMKRHAPSKVQCKLCSKEFTSNSDLEQHEDSEHWHLKNRPLKCSIDGCVKTFNYKHHLKRHQTASHMRVDYTCPECGRYMATSQQLRNHIRIHKGTYSYKCPKCARTYMRTNPFKRHALREHKWHLTDDEAKKMCIAVETKKIRERRSLNIENEHSD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -