Basic Information

Insect: Drosophila pruinosa
Gene Symbol: VEZF1
Assembly: GCA_018150935.1
Location: JAECWR010000094.1:8288548-8293165[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.00038 0.031 14.8 1.2 1 23 210 232 210 232 0.97

2 26 0.039 3.2 8.4 2.6 1 23 238 260 238 260 0.96

3 26 0.1 8.2 7.1 1.4 2 23 292 313 291 313 0.96

4 26 0.0022 0.18 12.4 4.1 1 23 387 410 387 410 0.93

5 26 0.44 36 5.1 4.3 2 23 419 442 418 442 0.93

6 26 2.8 2.3e+02 2.6 0.6 1 20 448 467 448 469 0.90

7 26 1.7 1.4e+02 3.2 1.4 1 23 490 512 490 512 0.96

8 26 0.00077 0.063 13.8 2.2 1 23 592 614 592 615 0.94

9 26 0.002 0.16 12.5 0.1 1 22 624 645 624 645 0.95

10 26 3.6 3e+02 2.3 5.4 1 23 654 677 654 677 0.95

11 26 8.5e-05 0.007 16.8 0.4 2 23 704 725 703 725 0.97

12 26 2.5e-05 0.002 18.5 3.7 1 23 733 755 733 755 0.99

13 26 0.038 3.2 8.5 2.2 1 23 905 928 905 928 0.94

14 26 0.011 0.88 10.2 0.9 2 22 936 956 935 956 0.95

15 26 0.011 0.88 10.2 0.4 1 23 965 988 965 988 0.93

16 26 5.1e-06 0.00042 20.7 2.3 1 23 1013 1035 1013 1035 0.98

17 26 0.00057 0.047 14.2 1.2 1 23 1042 1064 1042 1064 0.98

18 26 0.0069 0.56 10.8 0.0 2 20 1091 1109 1090 1111 0.93

19 26 0.0028 0.23 12.0 1.9 1 23 1156 1179 1156 1179 0.96

20 26 0.052 4.3 8.0 1.0 1 23 1216 1239 1216 1239 0.96

21 26 0.00083 0.068 13.7 3.5 1 23 1263 1286 1263 1286 0.97

22 26 1.2e-05 0.00096 19.5 0.1 2 23 1313 1334 1312 1334 0.95

23 26 4e-05 0.0032 17.9 2.9 1 23 1340 1362 1340 1362 0.99

24 26 1.9e-06 0.00016 22.0 2.0 1 23 1368 1390 1368 1390 0.97

25 26 5.3e-08 4.3e-06 26.9 2.3 1 23 1396 1418 1396 1418 0.99

26 26 0.00084 0.068 13.7 0.2 1 21 1424 1444 1424 1448 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.00038	0.031	14.8	1.2	1	23	210	232	210	232	0.97
2	26	0.039	3.2	8.4	2.6	1	23	238	260	238	260	0.96
3	26	0.1	8.2	7.1	1.4	2	23	292	313	291	313	0.96
4	26	0.0022	0.18	12.4	4.1	1	23	387	410	387	410	0.93
5	26	0.44	36	5.1	4.3	2	23	419	442	418	442	0.93
6	26	2.8	2.3e+02	2.6	0.6	1	20	448	467	448	469	0.90
7	26	1.7	1.4e+02	3.2	1.4	1	23	490	512	490	512	0.96
8	26	0.00077	0.063	13.8	2.2	1	23	592	614	592	615	0.94
9	26	0.002	0.16	12.5	0.1	1	22	624	645	624	645	0.95
10	26	3.6	3e+02	2.3	5.4	1	23	654	677	654	677	0.95
11	26	8.5e-05	0.007	16.8	0.4	2	23	704	725	703	725	0.97
12	26	2.5e-05	0.002	18.5	3.7	1	23	733	755	733	755	0.99
13	26	0.038	3.2	8.5	2.2	1	23	905	928	905	928	0.94
14	26	0.011	0.88	10.2	0.9	2	22	936	956	935	956	0.95
15	26	0.011	0.88	10.2	0.4	1	23	965	988	965	988	0.93
16	26	5.1e-06	0.00042	20.7	2.3	1	23	1013	1035	1013	1035	0.98
17	26	0.00057	0.047	14.2	1.2	1	23	1042	1064	1042	1064	0.98
18	26	0.0069	0.56	10.8	0.0	2	20	1091	1109	1090	1111	0.93
19	26	0.0028	0.23	12.0	1.9	1	23	1156	1179	1156	1179	0.96
20	26	0.052	4.3	8.0	1.0	1	23	1216	1239	1216	1239	0.96
21	26	0.00083	0.068	13.7	3.5	1	23	1263	1286	1263	1286	0.97
22	26	1.2e-05	0.00096	19.5	0.1	2	23	1313	1334	1312	1334	0.95
23	26	4e-05	0.0032	17.9	2.9	1	23	1340	1362	1340	1362	0.99
24	26	1.9e-06	0.00016	22.0	2.0	1	23	1368	1390	1368	1390	0.97
25	26	5.3e-08	4.3e-06	26.9	2.3	1	23	1396	1418	1396	1418	0.99
26	26	0.00084	0.068	13.7	0.2	1	21	1424	1444	1424	1448	0.91

Sequence Information

Coding Sequence: ATGTTGCCCCTAGATATATGCCGCACATGTGCGGTAAATAATGCCAATTTGTTGGCGCTTTCAACACGCACCGAGAAGTACGCAAATAAAAGTTTGTGTGACATGTTGCACGAATTAACACAAAATGATCCTCTGATGGAGCACTTGGATGACAATCTGCCTCAGTACTTATGCGACGACTGTTTACATAAGTTGGAAGAAGCCTACGCATTTGTGTTACAAGCACGACAGGTGCATGAGCAGCTGTTGCATAAAATACGAAAAAGTTTGCAGTGCCTGGACGAGCCACCAATAGACATATCCACGAATGACATAAAAACAGAAACGGACATTGCTTTGGAGCAAAGCCATAACACACCCAAATTGGAAAAGATTGCTATTGCATCTGTAGCCGCTTTTAAAATACAGCCAGAAAGTGACAGCGAAGTTAGTGATGCTAAGACAGTTGATGAAGACGTGTTGGACTTGAAGTCTTCGCAATTGAGGCGCAGTACACGGAAGGCAAAACTAGAAAGTGACAGCGAAAAGGAAGTGACTTCTGAGTGCTCGATTTCAATGCCGATCAAGCGACGACGGGGTCGTCCAGCACGCATTCCTAAGGAAGAAGCCATTAACAAAGACGGACGTCATGTATGCAATGTGTGTGGCAAGACATTCTCGTGGTATCGTGACATGCAACGCCATGCTCGTATACATTTTGAGCAGGCCGCGTATGAGTGTGAAACATGTGGCAAAAGATTTCTGCGCAAAGACAAATATAGTTTCCACTTGCGATCGCACGAGAAGCACCAAGCTAAACAGCAAGCACTGCAGCTGGGCAATGAGTGGAGCTTTGCTGAACGTCTTTATAGCTCAGGGCGCCTAAAGCGCATTGAATGTAAGCTGTGCGACTTAAAATGCCAACGAATTCAGGATCTGCGCGAGCATCTAAGTAGTCATATATCTATTGAGTCATTGTCGCATCTCAGCATTAATAGCGATGTTATGGAACACTTCTCCAGCCAGAAATTGGATTTGTGGCAAATTAAACAACAGGTGTGTTCAGATATAGCTACTGCAAATGATCAACTTGATAAGTATTGTCTTCTGATCAATGCGCATGGCTATGAGCTCAGTTTAAATGATTCGGACGAAGAGTTGGCTGGAAAACCTCCACCATATCACTGCTTTGCTTGCAATAAATCCTTCACACGTAAATATCGCCTCATGCGCCACACACTGGAGGAGCACACTCAGGAAATAACTTCTATTCAACGATGTAATATATGTCAAATTGGATTCGTATGCAAGAATTTGCTAGAGCAACATCAACGCACGCAGTGCCACAATCAATTAAAACACCACAGCTGTCCGAATTGTCCAGGCAAATTTATCTGGCTACAGAATCTGAAGCAACACGCGTGTGCTAATCGCACGGGTTTTCTAGAGAAGCATAAACCTGTCCTCAAAACAAATGTAACCCGCCAATTTCAATGTTGCCTGTGTGACGATTATGTAAACAGCATGTCAGCCCTACGCACTCATTTGGTCAAACATTGCGATGGACGAACCGGCATTGATTCTGCACAATCTGCTACCTACTTTCGTTGTTATTTTCCGGATGGAGTCACTTGTACCCAAGCGGAGCTGAGCCTGCGTATTGCTAACGATTTCAAAGTTCAGGATTATGGCCAATATTTTAATGCCTGCTCAGGCAGCGGGCAAGAATTGGATTTCTTTGACTCAGATACAGATGTAAGCGATGTTGAACAACAAACAACTACCTCTGCTCTGCATTCATGTGGTTTATGTGGCGTGTCAACAGTGCGTCTTTCTCAACTTCTGAGGCATCAACAAAATCATCACATTGACGTGAAGGACACATTGCCTCATGTTTGTGATAAATGTGGATTAGGATTTGTGGCTGAATCACTGCTTCAACAACATCTTCGTCGCGCATGTGACAAGCGACATGCGAAATATCATTGTCAGTGTTGCAACCTCAATTTTATTTGGCAGTCAAACTACGAGAGGCACTTGCAGACAAAACACGAAGGAGACGCAGGGGAAGAGCATAAGATCGCACCCAACACTAGATTAAGAAGCAAACGCCAGCAAGTAGCCAAGCTGCAATGTGATAAGTGCGATAAGGTTTTTATCTGGCCAAAGGATCTCACACGTCACAAGCGGATCCATCAGCCCGAGGCTTCAGCCCAGTACGAATGCAGCTTTTGTGAGCGCAAGTTCCACCGCAAGGATGGTTTGAAATCTCATATGCGTGTACACGGCGAACAGCCGGTTGATGCGACTCTCGTACATATGGGCGATTCAGATCAGTCTACGCTACAGCGGATGCCAATAGTGTTGAACCAATTGTGCCGATCGAATGGGTGCAAACAGATCCAGTGCATGATCTGCCTTTCGCAGCATTCAAAGATCTCTGATTTACGAACGCACTTGACCAAGCATCAGTTCACAGTCGAGTTTGTTGGGGAGCGTGCTAAGCCAGAGAGTATTGCGAATATTTGCAGAGGCTTATATCCGGAGCAGGTGACCCCACTGGACCAGCAACAATTGATAGAGCGTATTAAGAGGGACTTGGCCAAGGGTAGTGAGCTGGAAAGATTCGTTTCGATAACCAACGAGGCGGCAATTGAACTTAGCCTTGACAGTAGCGAAACTGAAACGGATTCAGACTCGGCCGAAACGGAAAGGAGTAGTACTGGCCGACAATACACTTGTGATTTGTGCCAGTTGCAGTTGACACGCAAACACAAACTATATGCTCACCAGCTGGATCAGCACACATGGCAAGAGGCGACACTCATCTGTTCACATTGCCAGGCTAAGTTCATCAGTGAGCAACTGCTGGAGCATCATTACAGAACTCTCTGTCGAAATGCCCAAAAGCGATTTCTTTGCCGAAAGTGCCCATTACGCTTTCGATGGCGGGACAACTTGAAGTTGCACATGGACGTGGCTCATCAAGAAGTTACTGGCGAACAGACGAATTTGGGAATTCAATTGACTTCGAGCAGTCTCCCTCCCGTACTTAGCTACGATTGTACTGATTGCAATCGTAGCTTTAAAATGCAAAAAGATCTCACACGACATACGCAGATGCATTCTCTGGAGTCGAGCATTTACCGCTGTCGTTGGTGTGCCCGGCGTTTTTATCGCGAAACTAATCTGCTGCAGCACATTGAGCGGCACGGCATCCAGGCCGGCCAGCTACCTTATGCTGAAGCTCTGCTAAATGCCAGCCGACATCCCCATGGTCAAAAACGCATCGAATGCAAGGTGTGCGATATTCGCTTCCCAACAATTGCCTCCCTGCGTTCCCATTTGACGTCCACGCCGAAAGGTACTCATCATGATATTAGCTCGATGCTCAACTACTCCATTACCAATCAACTCGGCTTTGAGCTGCATTTGGACGACTCGGAAACGGATGAGGAGACAAAGGCACCTGGCATACCCATGCAATACACATGCGGCATGTGCCAGCTCCGTTGTGCACGTAAATATGAGCTATCCCAGCATCAGCAGGCCATGCATAGGTTAGAACGAATAACAGATGGTTGTGATCAATGCATCTATAAAAGCGTTTCGCCGGATCTTATTGCCTACCACCGGCGTGCACAGTGTGCCAATACGGAAAAGCAATTCAAATGTGTTAAATGCAGCTACAAGTTTATGTGGGAGTCCAACTTATTACAGCACATACAGCTGCAACATCCTAGTAACGATAATCAGGGGAAGACAACATCAATGGCGTCACAGGAGCAACCAACTGAGAGCCAGATCTTTCAGTGCGGTCAGTGTCCGCGCAAATACAATCGAAAGGATCGACTGACGGCCCATGTGAAAAAGTGTCATATACCAGGGATTGATTCAACAGGAAATTCAACAAAAGCGGCTAAGGCTTCAGCTGCTGCCAAACAACAGAAAAGTTTCCTGTGTGCCTTTTGTGGCAAGGCGGTGAGCTCTTCCTCAAATCTCATTATACACATCCGACGCCATACTGGCGAGAAGCCATTTAAATGCGACTACTGCGATATGGCTTTTCCCCGCTCCTCCGACCTGCAGTGCCATCGACGCACCCACACGGGCGAACGGCCGCACGTCTGTACTGTATGTCAAAAGGGATTCGCGCGTTCATACAAGCTACAGCAGCATATGCGAATTCACAATGGCGAGCGCCCCTACAAATGTTCCTATTGTGATAAAAGCTTCACCCAGTCTAACGATCTGACGCTTCACATCCGAAGGCACACGGGCGAACGACCATATCAATGTGAGACCTGCGGGGAACGATTTATTCAGGGCACAGCACTCAAGAATCATAGACTACAAAACGGCCATTTCGAGGCCGGAGATGGTCTAACTAAAGATAATTAG
Protein Sequence: MLPLDICRTCAVNNANLLALSTRTEKYANKSLCDMLHELTQNDPLMEHLDDNLPQYLCDDCLHKLEEAYAFVLQARQVHEQLLHKIRKSLQCLDEPPIDISTNDIKTETDIALEQSHNTPKLEKIAIASVAAFKIQPESDSEVSDAKTVDEDVLDLKSSQLRRSTRKAKLESDSEKEVTSECSISMPIKRRRGRPARIPKEEAINKDGRHVCNVCGKTFSWYRDMQRHARIHFEQAAYECETCGKRFLRKDKYSFHLRSHEKHQAKQQALQLGNEWSFAERLYSSGRLKRIECKLCDLKCQRIQDLREHLSSHISIESLSHLSINSDVMEHFSSQKLDLWQIKQQVCSDIATANDQLDKYCLLINAHGYELSLNDSDEELAGKPPPYHCFACNKSFTRKYRLMRHTLEEHTQEITSIQRCNICQIGFVCKNLLEQHQRTQCHNQLKHHSCPNCPGKFIWLQNLKQHACANRTGFLEKHKPVLKTNVTRQFQCCLCDDYVNSMSALRTHLVKHCDGRTGIDSAQSATYFRCYFPDGVTCTQAELSLRIANDFKVQDYGQYFNACSGSGQELDFFDSDTDVSDVEQQTTTSALHSCGLCGVSTVRLSQLLRHQQNHHIDVKDTLPHVCDKCGLGFVAESLLQQHLRRACDKRHAKYHCQCCNLNFIWQSNYERHLQTKHEGDAGEEHKIAPNTRLRSKRQQVAKLQCDKCDKVFIWPKDLTRHKRIHQPEASAQYECSFCERKFHRKDGLKSHMRVHGEQPVDATLVHMGDSDQSTLQRMPIVLNQLCRSNGCKQIQCMICLSQHSKISDLRTHLTKHQFTVEFVGERAKPESIANICRGLYPEQVTPLDQQQLIERIKRDLAKGSELERFVSITNEAAIELSLDSSETETDSDSAETERSSTGRQYTCDLCQLQLTRKHKLYAHQLDQHTWQEATLICSHCQAKFISEQLLEHHYRTLCRNAQKRFLCRKCPLRFRWRDNLKLHMDVAHQEVTGEQTNLGIQLTSSSLPPVLSYDCTDCNRSFKMQKDLTRHTQMHSLESSIYRCRWCARRFYRETNLLQHIERHGIQAGQLPYAEALLNASRHPHGQKRIECKVCDIRFPTIASLRSHLTSTPKGTHHDISSMLNYSITNQLGFELHLDDSETDEETKAPGIPMQYTCGMCQLRCARKYELSQHQQAMHRLERITDGCDQCIYKSVSPDLIAYHRRAQCANTEKQFKCVKCSYKFMWESNLLQHIQLQHPSNDNQGKTTSMASQEQPTESQIFQCGQCPRKYNRKDRLTAHVKKCHIPGIDSTGNSTKAAKASAAAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCSYCDKSFTQSNDLTLHIRRHTGERPYQCETCGERFIQGTALKNHRLQNGHFEAGDGLTKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -