Dpro017076.1
Basic Information
- Insect
- Drosophila prostipennis
- Gene Symbol
- RIM101
- Assembly
- GCA_037075205.1
- Location
- JBAMCJ010006843.1:4094-10504[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0084 0.66 10.8 0.1 1 23 205 228 205 228 0.96 2 12 0.00032 0.025 15.2 4.3 1 23 233 256 233 256 0.94 3 12 3.3e-05 0.0026 18.4 1.9 1 23 261 283 261 283 0.98 4 12 7 5.5e+02 1.6 5.0 1 23 289 313 289 313 0.94 5 12 0.00068 0.054 14.2 3.9 3 23 324 345 323 345 0.95 6 12 0.002 0.16 12.7 0.4 1 23 351 374 351 374 0.95 7 12 0.0067 0.53 11.1 0.7 2 23 385 407 384 407 0.93 8 12 0.0004 0.031 15.0 0.3 1 23 435 457 435 457 0.97 9 12 9.1e-06 0.00071 20.1 4.0 1 23 464 486 464 486 0.97 10 12 0.00025 0.02 15.6 0.1 2 23 493 514 493 514 0.97 11 12 0.00029 0.023 15.4 0.8 1 23 521 543 521 543 0.99 12 12 0.00015 0.012 16.3 3.7 1 23 549 572 549 572 0.98
Sequence Information
- Coding Sequence
- ATGGAAACGTGTCGCACCTGTGCGATTTCCATGTTTGTGTGCGACTTCGAGaatggcagcagcaacacccaCTTCCTGGACCTCCACCATCCCAACTGCTGGCCCAGCGAGATGGCCCAAATTCGCCAGCAGTTCGTCAACTGGAATCTGAAGATCTCTCCCAATGATGGATTGCCCCAGAAAATCTGCAGCGACTGCTTCACCAAGTTCTGTTCGATAAACGCATTCCGAGTGGCTTGCCAGGAGGCGCAGTTGAAGCTGTCGAATATCTACGACAAGATCGATGCCAGCAGCCTGGAGGAGGAGCACCAGGAGGACTTGGACCAAGCGGAGGAGCACCAGGGAACAGAAACAACCAAATTAACAACGACGGTTTCAGCCGAAACACAACCAAGCACTGCCAGTGACACCATAGAGATTTTTGTGGATGCCGTAGAcatcgacgaggaggaggaggaggaggaggaggaggagcaaccGCCGGAGGAATATGCTACTCCGGAACTGACCATTAGCTATACCTGCAAGTTCTGCCTGCGGCCGGAGGAGAGCTATCAGCTGCAGCAACTTTTGCTGGAGCACATCAACACCAGCCACGACCCGGAGCAGCCGTACAATTGTCCGGAGTGCGAGGCCCGCTTCCAGGATGCCGCCTCGAGGACCGTGCACCTGAAGAACAGCCACGTGGAGAAGCAGCACGCCTGCGAGGTGTGCGGCAAGAAGTATGGCGATCGGCACAATCTGCGTCACCACGTCGAGAAGTACCATTCGGAGACGGACTTCGAGTGCGCGTTGTGCGAGAAGCGCTTCTACACCCGCAAGAGCCTCAACTACCACATGAAGTGGCACAATCCGGACCGCCAGTTCAAGTGTCGCCACGGTGGCTGCGAGCGGCTCTTCATCAGCCAGCGCCACCTTATGTGCCACGAGGCCACGCACTCCGGCACCAGCTCCAGGAAGAGCGAGCACTGCGGCTTCTGTGGAAAAACATTTATACACCTGAAGACCCTTCGCTGGCACATTTACAGACAGCACGGCGGCGAGAAGCCCTTCAAATGCTCCAACTGCACGGAGGTCTTCGCATCCTACGCGGAGAAGCGTATCCATATGCTGGAGCGGCACAGGGAGAATCTAACTGCCATCGAGCGGAGCGAGTGCATGTTGTGCCGCCAGCAGTTTTCCAGCGAGCAGGATCTGATCCACCACATGTCCGCGGAGCACCTGCAGCGTCCCGGGGCTCCGGTGATCGCCAACAACAAGCGGGTGTTGCAACAGAAGCGGGAACGACAGTACTCGGGACTCTTCCAGTGCGGCAGCTGCACCCAGCGCTTCAACATGAAGTCGGCGCTGGAGAGGCATGCCGCCGTTCACTCGGAGAAGGACCGGCCACATGCCTGTCCACACTGCTCCAAGAGATTCAAACGCGCCCAGGACATGAAGTGGCACATCAAGACGCACGAGAAGGAGAAGCCCAATGTCTGCGATGTCTGTGGAAAGGCCTTCGCCTTGAAGTATGTGCTCACGCAGCACCGGTTGAGTCATGAGGTACTGGAGAAAAACTTCAAGTGCAACATTTGCGGTCGCGCCTATCTGTTCGAGAAGTCATTGCGGCTGCATCAGCGAGTTCATACCGGGAAAACCTACTATAAATGCGATCTCTGTCAAGAGCGATTTGTCACGCACATTAAGCTTAAAACTCACATGCAAAAGACACACGCCGCCTCTGCGGACCACCCTCTGGATGATCTGATCAACATTGTGATTTCCTAA
- Protein Sequence
- METCRTCAISMFVCDFENGSSNTHFLDLHHPNCWPSEMAQIRQQFVNWNLKISPNDGLPQKICSDCFTKFCSINAFRVACQEAQLKLSNIYDKIDASSLEEEHQEDLDQAEEHQGTETTKLTTTVSAETQPSTASDTIEIFVDAVDIDEEEEEEEEEEQPPEEYATPELTISYTCKFCLRPEESYQLQQLLLEHINTSHDPEQPYNCPECEARFQDAASRTVHLKNSHVEKQHACEVCGKKYGDRHNLRHHVEKYHSETDFECALCEKRFYTRKSLNYHMKWHNPDRQFKCRHGGCERLFISQRHLMCHEATHSGTSSRKSEHCGFCGKTFIHLKTLRWHIYRQHGGEKPFKCSNCTEVFASYAEKRIHMLERHRENLTAIERSECMLCRQQFSSEQDLIHHMSAEHLQRPGAPVIANNKRVLQQKRERQYSGLFQCGSCTQRFNMKSALERHAAVHSEKDRPHACPHCSKRFKRAQDMKWHIKTHEKEKPNVCDVCGKAFALKYVLTQHRLSHEVLEKNFKCNICGRAYLFEKSLRLHQRVHTGKTYYKCDLCQERFVTHIKLKTHMQKTHAASADHPLDDLINIVIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00491676;
- 90% Identity
- iTF_00505570;
- 80% Identity
- -