Basic Information

Insect: Drosophila prostipennis
Gene Symbol: ZNF526
Assembly: GCA_037075205.1
Location: JBAMCJ010004410.1:410270-412299[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.098 7.7 7.4 0.3 1 21 328 348 328 349 0.95

2 10 7.5e-07 5.9e-05 23.5 0.3 1 23 357 379 357 379 0.98

3 10 0.0066 0.52 11.1 2.0 1 23 382 405 382 405 0.91

4 10 1.8e-06 0.00014 22.4 0.8 2 23 412 433 411 433 0.98

5 10 2.1e-07 1.7e-05 25.3 1.3 1 23 439 461 439 461 0.95

6 10 4.4e-06 0.00035 21.1 0.6 1 23 467 489 467 489 0.99

7 10 0.00067 0.053 14.2 2.9 1 23 495 517 495 517 0.98

8 10 0.0011 0.085 13.6 0.3 1 23 523 545 523 545 0.98

9 10 0.0001 0.0079 16.8 3.7 1 23 551 573 551 573 0.99

10 10 0.0017 0.13 13.0 0.0 1 23 579 601 579 601 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.098	7.7	7.4	0.3	1	21	328	348	328	349	0.95
2	10	7.5e-07	5.9e-05	23.5	0.3	1	23	357	379	357	379	0.98
3	10	0.0066	0.52	11.1	2.0	1	23	382	405	382	405	0.91
4	10	1.8e-06	0.00014	22.4	0.8	2	23	412	433	411	433	0.98
5	10	2.1e-07	1.7e-05	25.3	1.3	1	23	439	461	439	461	0.95
6	10	4.4e-06	0.00035	21.1	0.6	1	23	467	489	467	489	0.99
7	10	0.00067	0.053	14.2	2.9	1	23	495	517	495	517	0.98
8	10	0.0011	0.085	13.6	0.3	1	23	523	545	523	545	0.98
9	10	0.0001	0.0079	16.8	3.7	1	23	551	573	551	573	0.99
10	10	0.0017	0.13	13.0	0.0	1	23	579	601	579	601	0.95

Sequence Information

Coding Sequence: ATGGATGTGGACAAGATTTGCTTGACTTGCCTGAGCTCGACGGAACCCTTTCTGTCCATTTACGACGGAGGATCGGGGAGCTGCCTGGCGGACATGATCCGGGATTTCACAAAAACCAAGCCTCGCCGTCACGACAATCTTCCGCAGAAAGTGTGCCTGGGCTGTCTGAGTGAGATCTCAAGGTGCTACACCTTCAAGATCAAGTGCGAGAACTCCAGTCGTACCCTGCGCCAATTGCTGCCGAATGCCCTGCCCGAGGAGCCGGAGGAGAAGGTGTCCATCAGTGGGCCAGTGTCCACGGCGGATCAGGCTGTGCAGACGACCAGCTGGGAGCCCATCAGATGCACTGCCTCCGTGCAAACAGATGCGGTGGCCACCACGGATGCCGAACAGAACACCAGCCTGGTCAAGTCGACGATTTCGGTGGATCTGGATTACGACGGCGAGGGAGAGGTTTTTGACTACGAGCTGCCGGATGAGCCCGTGGAGAAGACCACCAGCCTCATCCTGCAGGTCCAGGCCGGCAGCTTGAAGGAGGAAAAGCAAGTGGTGTTCACCCAAACCAATGTCATTTACGAGGGCGATGACAACGAGCTGGAGCAGCAGATTAGGGAATGTAACCTGGCCATTTTCGAGGGAGTCGACAACGAAACGGAGGTCATCACAGTAGCCGCTCCACAGGTGACCACCAGAAAGAGCGCTGCCAAGCTCTTGACGCAGCAGCAAAGCGAAAAGGAAGAGAATGCTGCGAGTCCCAAAGAGGAAGTGGCGGAAGAAGAGAAGCTTGCGCAGCCGACTAAAAGAGCCTCACGCCGGCGGGCAGTGGTCAAGCAGGACGTGCAGGCCACGCCTGCGGCAGAAGCAGCTTCTCCCTCCAAGCAGCTTCGGTTAGGAACACAGCGCAAATCCCTGAATGCCGTCGGAGGAGCAACAGTAAGCGCAAGCACAGCTTCTTCTACAGCCTCGACACCTGAACTAAAATATCACTGCGATCGCTGCAATGCGGGCTTTGCGCTGGAGAAATCCTTGATGATCCATAGACGTCAGAAGGGCTGCATAAACCGCAACTTCAAGTGCAACGAGTGCGAAAAGGTCTTCGTGTCACCGGATCATTTGGCAGAGCACCAGGCCAGTCATGGTGCTCACAATTGCCAGGAGTGCGGAATTCAGTGTGATTCCAAGGAGCAACTGAGCAAGCACCTGGTCCAGGGCCACAAGAGGAATCTGCGCAATCAGTGCACCGTTTGCCAGAAGGTATTCACGATGCTATCCACGCTGCGTGACCACATGCGCATCCACACCGGCGAGAAACCCTTTTTGTGCAATATCTGCGGCAAGAGCTTCACCCAGAACGCCAATCTGCGCCAGCACAAGCTGCGTCACTCGGAGACAAAGAGCTTCAAGTGCGAGCTATGTCCGCACTCGTTCGTGACTAAGGCGGAGCTCGCCTCGCACGCCCGCACCCACACCGGTGACAAGCCCTTCGAGTGCGATGTGTGTCTGGCCAGGTTCACCACCAGCTGCTCGTTGGCCAAGCACAAACGGAAGCACACCGGCGAGCGGCCATACGCCTGCGATCTGTGCCCCATGAGATTCACAGCCCTGAACGTACTGAAGAACCACCGAAGGACGCACACAGGTGAGCGGCCGTATGTCTGTCCCTTCTGCTCGAAGACCTTCACGCAACGCGGCGACTGCCAGATGCACCAGCGTACCCACCAAGGCGATCGCATTTACATTTGCCCGGTGTGCAACGAGGAGTTCAAATCGATGCCCGACATGCGATCCCATTTGGCCGGCCACGAGCAGCACGACAAACGGCTGGTCCACTTCAACTTTCTGAGCAACAAGGAGAACGGAAGCGGAGCCCTCGAGGAGGACCTTAATGAGATGGCCGAGACTGCGCTAATGCTATAA
Protein Sequence: MDVDKICLTCLSSTEPFLSIYDGGSGSCLADMIRDFTKTKPRRHDNLPQKVCLGCLSEISRCYTFKIKCENSSRTLRQLLPNALPEEPEEKVSISGPVSTADQAVQTTSWEPIRCTASVQTDAVATTDAEQNTSLVKSTISVDLDYDGEGEVFDYELPDEPVEKTTSLILQVQAGSLKEEKQVVFTQTNVIYEGDDNELEQQIRECNLAIFEGVDNETEVITVAAPQVTTRKSAAKLLTQQQSEKEENAASPKEEVAEEEKLAQPTKRASRRRAVVKQDVQATPAAEAASPSKQLRLGTQRKSLNAVGGATVSASTASSTASTPELKYHCDRCNAGFALEKSLMIHRRQKGCINRNFKCNECEKVFVSPDHLAEHQASHGAHNCQECGIQCDSKEQLSKHLVQGHKRNLRNQCTVCQKVFTMLSTLRDHMRIHTGEKPFLCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELASHARTHTGDKPFECDVCLARFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRTHQGDRIYICPVCNEEFKSMPDMRSHLAGHEQHDKRLVHFNFLSNKENGSGALEEDLNEMAETALML

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505549;
90% Identity: iTF_00548219;
80% Identity: -