Dpro014714.1
Basic Information
- Insect
- Drosophila prosaltans
- Gene Symbol
- -
- Assembly
- GCA_018151275.1
- Location
- JAECWY010001717.1:762125-765325[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.59 51 4.8 3.7 2 23 235 257 234 257 0.94 2 17 0.72 63 4.5 0.1 1 23 265 290 265 290 0.94 3 17 0.037 3.2 8.6 2.1 2 23 301 322 301 322 0.93 4 17 9.1 7.9e+02 1.1 0.3 3 23 363 384 362 384 0.89 5 17 0.017 1.5 9.6 1.4 1 23 390 412 390 412 0.95 6 17 0.00022 0.019 15.6 2.0 1 23 420 443 420 443 0.98 7 17 1.4e-05 0.0012 19.3 0.6 2 23 448 469 447 469 0.97 8 17 0.00077 0.067 13.9 1.9 1 22 517 538 517 541 0.91 9 17 1.4 1.3e+02 3.6 0.8 4 21 549 566 548 567 0.88 10 17 0.0041 0.36 11.6 1.2 1 23 586 611 586 611 0.96 11 17 0.017 1.5 9.6 1.7 2 23 638 660 637 660 0.94 12 17 0.009 0.78 10.5 0.8 2 23 666 688 665 688 0.93 13 17 0.0071 0.62 10.8 0.3 2 23 692 714 691 714 0.94 14 17 4e-06 0.00035 21.1 2.2 1 23 720 742 720 742 0.98 15 17 0.002 0.17 12.6 2.9 1 23 746 769 746 769 0.94 16 17 4.1e-05 0.0036 17.9 1.2 1 23 775 798 775 798 0.97 17 17 0.0035 0.3 11.8 0.2 1 23 802 830 802 830 0.93
Sequence Information
- Coding Sequence
- ATGGACATGGACAAGAAGTTACAAAATTTGTCTAATAAAATCTGTCTGCATTGTACAGTGCACAATCCAAAATTAAAATACCATGAAATTTTTAAAGATCTTGGCGCGGAAATTGGATTGCAAAAATTGCTTGCAAAGCATTTTCATTTCGAGGTGGAATTTTCCGCGAAGTCTCAGTTGATTTGCGAGGTGTGCGTCAACACTTTAATACGTTTTTTTGACATCGATGAGTTGGAGCGAGAGCAGCACAAGAAGGTGCCTCAGATTGTGTCCCAAAGAGCTGCCCAGACTAGTCATGTTACAAGTACTTCGAATGTAACAATCAATGAAGCTACCGAGAAAAAGTCAATTATAGACGAGTCTACTATATATGACCTAATATTCAAATCGGATGATGATGTATCTTCCACCTCTGTGTTGGAGGAGGAGCAGGAGGACGAGGAGGAAACCAATGCCCCAACTAAGTCAGATCAAGAGAGAAATGAGGATGGTGTGGATTTTGAATTGGAGAGTGATCAGGACTTAGAGGCCGATTTGCAATCTAAGCCAGATGAAGATGAAGATGGCATCGAAACAGAAAGCAATGTGATAGTTTTCAATTTTGTTGAGATTACAGAAAAGGATAACATTGATGATTTATATGCATACTTGGCCACTGTGGTGAAAACGAAATTTGAAAACTTATCATTTGAGTGGAGCACCACATGCAAACATTGTTCTTTGCCATGTTCCAACTATCAGAGTATATTTAGCCATATGCTGGAGTTGCACAAAGGCCTTAAGGATGGCTCTTTTGAGTGTCCGTTTGAAGGATGCTCGGCGAAACTTAAAGACAAACAATTTCTGGCCATGCATTTGGTTATGCTGCATGGTCCAGTAGTCAATATACCGATATATGGCAGTTGTCCGGAATGCAAATTGACATTCTCAAACATTTTACAATATAATAAACATTCCTGCGCCCATGTGATTAAGAAGAAACGTGGCATGAGACTGTATTGCGAAATGTGTTCCATTGAGTTTCCATCTTGGAAACGTTTTAATTTTCATAATCAGTTCCATTTGGAGAGGCATAGACCTAGAGCCTGTTTTGTCTGTAACTATGCGGATACCAATATCGATGATCTCTTCCAGCATTTGCATTATGCCCATGAACCTGAGAGCAAATTCTTTTGTAAGCTGTGTGATCGCAAATTTCGTGATGAAGCTGTCTTTCTGGAGCACAACAAATCCCATGGAAATGCCAGCAGCAGCACTTACACCTGCAACGAATGTTTCCTCAGTTTTGATACTCGCAGTCGGTTTAATGGACATATGCGTTCGATGCATGGTACTTTCATTAGTTGCGAAATCTGTTCCCGGGAATTCTCCAGTGAATCCACCTACAATGCGCATATGAAGAAGCATTTGATTATCGAACGGGAAGTCCATATATGCCGGAATTGTGGCCAACTGAATGAGCATGAAAATAAAATGCTTCAACATATAGAATCTGAATCGCCAAATTGCCACGAATCGGAGGTATATACCGATACATTGCGCAATGCTTACGTATGCGAATATTGCTCAAGTTACTTTCGTGATAAATCGGATTTGCACAATCATCGCCAGTCGGGAGTACATAATAATGGGATGTTTTGGTGCCAACCTTGTGCTAAGGAATTCACCGATATGAAACTCTATCGTCATCATTTGAGAAACTTTCAACAATTGAAATCGGATACGGAACATCGAAGATTTGAGATATGCTTGTACTATATGTGTGATCAGAAGGATTGCTTTGAATCTTATGCCAATTGGAACTCCTTGTACACTCATAAACGGCGCACTCATAGTAAGAATCAGTCTAAACTAGATCAGACTGAAAATGCATCCACATCCCAAGCAGCTGTGAAGGACAAACCGGAATGGCAATGCCAATTTTGTGAAAAGGAATGCCGCTCCAAAATGTCCCTTTCGGTACATGTGGCACGAAGTCATAATAATGATAATGTTGTCTGTACCATTTGCAAATCATCATATAAGAATCAAGCCGCATTGGATAAACATCATTCCTATTGGCATGAGCCCATCGAGTGTCCGAAATGCTTTAAGGTTGTTAAAAATCGTCGCAATTACGACACCCATGAGAATGTTGTTCATTCAAATAATAAACGCTATTCCTGCGATATTTGTGACAAGGGCTTCTATCACAAGAGCGAAATGAAGGCACATCAAAAGCTCCATTCTGTTTTGTATAGTTGCAAACATTGCAATTTTACCACTCGAAATAAAACTTCCTTATCGGTTCATGTGATGGGACAGCATTTTAAACGTTTTGCCTTCTCCTGCAAAATGTGCTCGAAGCGTTTTGGCCGTCGTCAGGGATTGGCCACCCATATGCAGCGTGTGCATGGAACTAAATATACCTGTGAGGAATATTTTACAGGCGGTTGCAATCGAAGTTTTGCCTCCACTGCGCTATTGAGTCAGCATGTAAAAAGAGTTCACAAGGGTAGCATATTTTTGCCAGATGATATACTCGAGGAGGAATTCGAAGAGCAGGACGAACTAGAGGAGCTGGACGATGAAGACGCGGTAACAGACGAGGAGAATGCTCCGTCGTCATCCAAGAAACGTTGTTTTCAAATAAATGATACTAAAATTGAGTTTATCGAAGAGGGAGCTGAGGATATTGAGGAGTTTATAGATGAGGATCAGGAGATAGACGAAGTGAAGGGTCATAAGAAGAAATAA
- Protein Sequence
- MDMDKKLQNLSNKICLHCTVHNPKLKYHEIFKDLGAEIGLQKLLAKHFHFEVEFSAKSQLICEVCVNTLIRFFDIDELEREQHKKVPQIVSQRAAQTSHVTSTSNVTINEATEKKSIIDESTIYDLIFKSDDDVSSTSVLEEEQEDEEETNAPTKSDQERNEDGVDFELESDQDLEADLQSKPDEDEDGIETESNVIVFNFVEITEKDNIDDLYAYLATVVKTKFENLSFEWSTTCKHCSLPCSNYQSIFSHMLELHKGLKDGSFECPFEGCSAKLKDKQFLAMHLVMLHGPVVNIPIYGSCPECKLTFSNILQYNKHSCAHVIKKKRGMRLYCEMCSIEFPSWKRFNFHNQFHLERHRPRACFVCNYADTNIDDLFQHLHYAHEPESKFFCKLCDRKFRDEAVFLEHNKSHGNASSSTYTCNECFLSFDTRSRFNGHMRSMHGTFISCEICSREFSSESTYNAHMKKHLIIEREVHICRNCGQLNEHENKMLQHIESESPNCHESEVYTDTLRNAYVCEYCSSYFRDKSDLHNHRQSGVHNNGMFWCQPCAKEFTDMKLYRHHLRNFQQLKSDTEHRRFEICLYYMCDQKDCFESYANWNSLYTHKRRTHSKNQSKLDQTENASTSQAAVKDKPEWQCQFCEKECRSKMSLSVHVARSHNNDNVVCTICKSSYKNQAALDKHHSYWHEPIECPKCFKVVKNRRNYDTHENVVHSNNKRYSCDICDKGFYHKSEMKAHQKLHSVLYSCKHCNFTTRNKTSLSVHVMGQHFKRFAFSCKMCSKRFGRRQGLATHMQRVHGTKYTCEEYFTGGCNRSFASTALLSQHVKRVHKGSIFLPDDILEEEFEEQDELEELDDEDAVTDEENAPSSSKKRCFQINDTKIEFIEEGAEDIEEFIDEDQEIDEVKGHKKK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00501293;
- 90% Identity
- iTF_00483932; iTF_00591180;
- 80% Identity
- -