Basic Information

Insect: Drosophila prosaltans
Gene Symbol: MET32
Assembly: GCA_018151275.1
Location: JAECWY010002308.1:1415158-1419784[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.00083 0.072 13.8 1.2 1 23 211 233 211 233 0.96

2 23 3.9e-06 0.00034 21.1 1.4 1 23 239 261 239 261 0.98

3 23 0.042 3.6 8.4 2.7 2 23 290 311 289 311 0.97

4 23 0.039 3.4 8.5 6.2 1 22 386 407 386 409 0.90

5 23 2.5 2.2e+02 2.8 0.4 3 23 480 500 479 500 0.95

6 23 0.00036 0.031 14.9 1.8 1 23 580 603 580 603 0.97

7 23 0.81 71 4.4 4.2 1 23 642 665 642 665 0.97

8 23 2.9e-05 0.0025 18.4 0.5 2 23 690 711 689 711 0.97

9 23 5.2e-06 0.00046 20.7 2.5 1 23 719 741 719 741 0.98

10 23 0.033 2.9 8.7 1.2 1 23 888 911 888 911 0.95

11 23 0.03 2.6 8.9 1.2 2 22 920 940 920 940 0.94

12 23 1.2 1.1e+02 3.8 5.7 1 23 949 972 949 972 0.95

13 23 5.3e-05 0.0047 17.5 6.0 2 23 987 1008 986 1008 0.96

14 23 0.00013 0.011 16.4 0.9 1 23 1014 1036 1014 1036 0.98

15 23 0.0011 0.092 13.4 0.2 2 21 1063 1082 1062 1083 0.94

16 23 0.0079 0.69 10.7 4.8 1 23 1129 1152 1129 1152 0.96

17 23 5.5 4.8e+02 1.7 0.5 1 23 1189 1212 1189 1212 0.87

18 23 6.5e-05 0.0057 17.2 1.8 1 23 1246 1269 1246 1269 0.98

19 23 5.2e-06 0.00045 20.7 0.2 2 23 1306 1327 1305 1327 0.95

20 23 0.00072 0.063 14.0 3.0 1 23 1333 1355 1333 1355 0.99

21 23 2e-06 0.00018 22.0 2.0 1 23 1361 1383 1361 1383 0.97

22 23 1.8e-07 1.6e-05 25.3 2.4 1 23 1389 1411 1389 1411 0.99

23 23 0.00067 0.059 14.1 0.1 1 21 1417 1437 1417 1441 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.00083	0.072	13.8	1.2	1	23	211	233	211	233	0.96
2	23	3.9e-06	0.00034	21.1	1.4	1	23	239	261	239	261	0.98
3	23	0.042	3.6	8.4	2.7	2	23	290	311	289	311	0.97
4	23	0.039	3.4	8.5	6.2	1	22	386	407	386	409	0.90
5	23	2.5	2.2e+02	2.8	0.4	3	23	480	500	479	500	0.95
6	23	0.00036	0.031	14.9	1.8	1	23	580	603	580	603	0.97
7	23	0.81	71	4.4	4.2	1	23	642	665	642	665	0.97
8	23	2.9e-05	0.0025	18.4	0.5	2	23	690	711	689	711	0.97
9	23	5.2e-06	0.00046	20.7	2.5	1	23	719	741	719	741	0.98
10	23	0.033	2.9	8.7	1.2	1	23	888	911	888	911	0.95
11	23	0.03	2.6	8.9	1.2	2	22	920	940	920	940	0.94
12	23	1.2	1.1e+02	3.8	5.7	1	23	949	972	949	972	0.95
13	23	5.3e-05	0.0047	17.5	6.0	2	23	987	1008	986	1008	0.96
14	23	0.00013	0.011	16.4	0.9	1	23	1014	1036	1014	1036	0.98
15	23	0.0011	0.092	13.4	0.2	2	21	1063	1082	1062	1083	0.94
16	23	0.0079	0.69	10.7	4.8	1	23	1129	1152	1129	1152	0.96
17	23	5.5	4.8e+02	1.7	0.5	1	23	1189	1212	1189	1212	0.87
18	23	6.5e-05	0.0057	17.2	1.8	1	23	1246	1269	1246	1269	0.98
19	23	5.2e-06	0.00045	20.7	0.2	2	23	1306	1327	1305	1327	0.95
20	23	0.00072	0.063	14.0	3.0	1	23	1333	1355	1333	1355	0.99
21	23	2e-06	0.00018	22.0	2.0	1	23	1361	1383	1361	1383	0.97
22	23	1.8e-07	1.6e-05	25.3	2.4	1	23	1389	1411	1389	1411	0.99
23	23	0.00067	0.059	14.1	0.1	1	21	1417	1437	1417	1441	0.91

Sequence Information

Coding Sequence: ATGTTGCCCTCGGACATTTGTCGGACCTGTGCCACGCAGCACAACAACTTATTACCGCTTGCCTCCTGTATGGAAAAACTTCAAGAATTAACGCAAATTCCTCTATTGGAGCAGGGCGATGAAAATTTACCACAGCATTTGTGTGTCGATTGTTTGGCCAAATTGGAGAATGCTTATGCCTTTGTAGAGCAAGCTCGTAAGGTGAACAGGGAGCTGTTAATGAAGTTGAGGCAATGCTTCTTAGAGGAAACACCTATTGATATCCCAATACCAAACACCATGCAGCAACAGATCAAAATGGAAATGGACGAGGAAGAAATTGGACACCAACAAGCTGATGAGGAAGAGGTAGCAGCCACAAGATTGGAATTAAAGTGGCAGGCGGATAGTGAAGCAGAAAGCGAAGCTGAGGAGGAGCCTGCGGATTGTCAAGAAGATGAATACAAACCATATCAGCTAAGACGAAGTCTACGTAAGATCAAACAGCAATCCGATAGCGAACAGGAGGATCAGCAGCCGGAGGAAGAGGAGAACAACGAACTAAGCCTAAGTCCAGAGCAGCCACCCAAACGTCGACGTGGTCGTCCACCCCGAGTAGCGAAATTGCAAGCCCTTAATCCTGATGGGCGTCATGCATGTTCGGAGTGTGGGAAGACCTTCTCCTGGTATCGAGATATGCAGCGTCATGCTCGCATCCATTTCGAAGATGCCGCATACAATTGTCCACAGTGTGGTAAGGGATTCATACGGAAGGATAAGTACAAATCTCATTTGAAGTCGCATGAGAAGCGCCTGGCGAAACAAGAGCTGGCTAAAGAATTGAGATTCGCAGAACGACTGTACAGTTCTGGCCAACTAAAGCTCATAGAATGCAAGTTATGCAATCTTAAATGTCAAAAGTTAAAAGATTTAAGGGCCCATTTAAAGAGCCATTCATCCAAAGAAACTCTCAGCCAATTGAAATTGGATCAAGAAGCGGTGAAGGAAAACTTTGGCGATGAATATGTTGACATAGAAAAAGTCAAAGATTTAATAACAAAAGATATAAGTGAGGGACACTTGGATAAATTCTGTGCTGTTGTCAACTCCCATGGTTATGAATTATGTTTAAGTGATTCTGATGAAGATTTGCCTTCTGATGGCGAAGAACCCAAATACCACTGTCATTCCTGTAATCTGTATTTTAAGCGTAAGCATCTCCTAATACGTCATACAGTGGAGGAACATTCGCAAGTTGATAATCAGCCCCATCTAAGGTGCAATTTATGCCACATTGGTTTTGTCTGCTTCATTTTGTATGAGCAGCACAAACGTTCGCAGTGTAATGGTAAATTCAAGCGGTATGGATGTCGCCAGTGTCCTGGAAAGTTTATTTGGTTGGAGAATCTACAAAAACATGACTGTCTCCAAAACAGAGAAGAAGACAAGCAAATTCTATGTTGCCTATGCGATTCTCAATTGCCCAGTTTGGTCCAATTGAGAGCCCATTTAGCCAGTCATCAGGATGGCATAACTGGCATCGATCCTCTATATCAAGCAACATTTTTCCGCTGCTATTATCCCAAGGGCTTAGCATGCAGTGAGTCCGAACTGAGCAATCGCATAGCTAGTGACTTTGAGGCTCACGAATTTAGTCGCTATTATAATGCTAGCCTTAGCTCTGGGCAAGAATTGGATCTATACGACTCCGATACGGATGAAAGTGATGAACCGGGAAAGTCTCAAGAGAAACCCATTCACACATGTCCCCTATGCGGTAAATCAATGAAGCGCTTAACCAATCTTCTTGAACACCAACAGAGTTTCCATCAAGAAGAAATGGAATCGTTTGCCTTTTCTTGTTGGACTTGCTCGGAAAGATTTCTCTGCGAAGCACTGCTAAAGCAGCATCGACGTCGATCATGTGGCAAATCCCATGCTAGATTCCATTGTCAATTGTGCCGCATGCATTTTGTGTGGCAGACAAACTATGAGCAACATTTGCGCGTGAATCATCCATCAGATAGGGAATTGGCTCCCAACATTGCCAACAAAATCAGCTGGAAAACTTCTGCTGCGCCCAAGTTGAAATGCAATGATTGTGATAAGGTCTTCATCTGGCCGAAGGACCTTAATCGTCACAAGCGTATGCATCAGCCCAGAACGGCATCTCAGTTTGAGTGCCCATATTGTGAACGTAAATTTCATCGCAAGGATGGTCTCAAATCGCATTTGCGGGTGCACAGCGAGCACCAGCAGTTGGAGAAGCTTGAGAATGATGATCAAATGAATGATGAGAAGTCTCCATCAAATCAGATTTTAGCGGAACTTAGTCGGCCACATGGCTGCAAGCGTATTCAATGCATGATTTGCCTATCCCAGCACTCAAAGATAGCGGATCTGCGGTGTCATCTTATGACCCATCAATTTGTCATCAGTTTGCCTACGGAGAGGGAGCAAGATATAGTTGGTGTATCCAAATCGCTATATCCCGAACTGAATGTGACCCTAACAAGAGATCGTTTGATATCCCGAATCATGAATGATATAGGCAAGGGTGTGGAACTGGAGAGATTCATATCCATTACCAATGAAGCTGGCATTGAACTTAGTTTGGATAGCAGCGAAACGGACACAGATTCTGAGGAGGAATCAAATGATAAACGACAAAATTTGAATCGATATTCTTGCTCCATTTGTCAAGTGGAGGTGCAAAGAAAACACCAACTTTATGCCCATCAATTGGAGAAGCATTCTAGTGGAGAGTCAGTCACAAATGTGTGCTCGCATTGCCAGTCAAGATTTGTGAGTGAGCAACTCCTTGAACATCATCTAAGATCCCAGTGCAGAAATAATCAGAAACGTCATCAGTGCAGGAAGTGCTCTTTGCGCTTCCGTTGGCGGGACAACCTTAAACTCCACTCAAATGTTTGCCATCAGGCAGACGATTCCTTATTAGGGGCAGAGGGTGGAGAATTGCATTGCAAGGAATGCCATCGTAGCTTCAAAATGCAGAAGGATCTGACCCGTCACATGCTGATGCACTCGGACACAAGTATCTATCGTTGTCGTTGGTGTGCCCGTCGCTTCTATCGCCAGGCCAATCTTCTACAACACATTGAACGACATGGCATTAGCGCTGATCAATTGCCCTACGCGGAATCGCTACTCAATTCATATAATCATCCACACGGACAAAAGATCATCTCATGCAAAGTATGCAACATTAACTTTAACTCTATCTCTGAGCTACGTCGCCACTTAAAGGACGCTCCCAAGGAGACGCACCATGACCTTGGCTCCATGCAAAATTATTCCATAACCAATGAATTGGGCTATGAATTGCATTTGGACGATTCTGAAACAGATACGGAGGATGTCAAGTCTGGAGGGAGAAACGAAGTTTACACTTGCAGCATGTGTCACTTGCGTTGTGCAAGAAAGTATGAACTTTATCAGCATCAACAGGCTATGCACAGGTTGGAGCGAATCCCAGATGGCTGTGATCAGTGCATCTTTAAAAGCGTGTCTAATGACATTATCGAGCATCATAAACGTAGTCAGTGTAAAAATCAGGAAAAGCCCTTTAAATGTATTAAATGTGGCTATAAATTCATGTGGGAATCCAATATGTTAATGCACGTGCAACTTCAGCATGCAAAAACCGAAGAGGAAGAACAAATCCAGGAACAACCCATGGAACAACCAGACTCCTCAATGGTTAATTCGTCCAACCCAAAACAAATGCAACAAATTTTCCAATGCGCCCTCTGTCCTAGGAAATACAACCGCAAAGATCGTCTAACAGCGCATATGAAGAAGTTTCACAATCCGGGTGGGGCTACCAGCCAGTCTCCTGCTCCGTCAAAGAAATCCTCGGCAGTAGCAGCAGCTTCATCGTCATCTATAGCCTCCCCTAAGCAACCGAAACTATTTTTGTGCGCATTCTGTGGCAAAGCAGTCAGTTCCTCCTCTAATCTAATCATTCACATGCGTCGGCACACAGGTGAAAAGCCCTTCAAGTGCGATTTCTGCGAGATGGCTTTCCCTCGTTCTTCTGATCTCCAATGTCATCGACGCACACATACAGGGGAGCGACCCCATGTCTGCACAGTGTGTCAGAAAGGATTTGCCAGATCCTATAAATTGCAGCAACATATGCGCATCCACAATGGAGAACGCCCGTACAAGTGCACCTATTGCGAGAAGAGTTTCACCCAATCCAATGATTTGACCCTGCACATACGACGACATACCGGAGAGCGGCCCTACCAATGTGGCATCTGTGGCGAGCGGTTCATTCAGGGTACTGCCTTAAAGAATCATCGTCTGCAACAAGGCCACCATGAGCCAGGTATTCCGGGTGGATTGCCGGGAGAGGCGCCCCCAAGGCGCACAGTTCTCCAGCAATTTACGGGCGAATGA
Protein Sequence: MLPSDICRTCATQHNNLLPLASCMEKLQELTQIPLLEQGDENLPQHLCVDCLAKLENAYAFVEQARKVNRELLMKLRQCFLEETPIDIPIPNTMQQQIKMEMDEEEIGHQQADEEEVAATRLELKWQADSEAESEAEEEPADCQEDEYKPYQLRRSLRKIKQQSDSEQEDQQPEEEENNELSLSPEQPPKRRRGRPPRVAKLQALNPDGRHACSECGKTFSWYRDMQRHARIHFEDAAYNCPQCGKGFIRKDKYKSHLKSHEKRLAKQELAKELRFAERLYSSGQLKLIECKLCNLKCQKLKDLRAHLKSHSSKETLSQLKLDQEAVKENFGDEYVDIEKVKDLITKDISEGHLDKFCAVVNSHGYELCLSDSDEDLPSDGEEPKYHCHSCNLYFKRKHLLIRHTVEEHSQVDNQPHLRCNLCHIGFVCFILYEQHKRSQCNGKFKRYGCRQCPGKFIWLENLQKHDCLQNREEDKQILCCLCDSQLPSLVQLRAHLASHQDGITGIDPLYQATFFRCYYPKGLACSESELSNRIASDFEAHEFSRYYNASLSSGQELDLYDSDTDESDEPGKSQEKPIHTCPLCGKSMKRLTNLLEHQQSFHQEEMESFAFSCWTCSERFLCEALLKQHRRRSCGKSHARFHCQLCRMHFVWQTNYEQHLRVNHPSDRELAPNIANKISWKTSAAPKLKCNDCDKVFIWPKDLNRHKRMHQPRTASQFECPYCERKFHRKDGLKSHLRVHSEHQQLEKLENDDQMNDEKSPSNQILAELSRPHGCKRIQCMICLSQHSKIADLRCHLMTHQFVISLPTEREQDIVGVSKSLYPELNVTLTRDRLISRIMNDIGKGVELERFISITNEAGIELSLDSSETDTDSEEESNDKRQNLNRYSCSICQVEVQRKHQLYAHQLEKHSSGESVTNVCSHCQSRFVSEQLLEHHLRSQCRNNQKRHQCRKCSLRFRWRDNLKLHSNVCHQADDSLLGAEGGELHCKECHRSFKMQKDLTRHMLMHSDTSIYRCRWCARRFYRQANLLQHIERHGISADQLPYAESLLNSYNHPHGQKIISCKVCNINFNSISELRRHLKDAPKETHHDLGSMQNYSITNELGYELHLDDSETDTEDVKSGGRNEVYTCSMCHLRCARKYELYQHQQAMHRLERIPDGCDQCIFKSVSNDIIEHHKRSQCKNQEKPFKCIKCGYKFMWESNMLMHVQLQHAKTEEEEQIQEQPMEQPDSSMVNSSNPKQMQQIFQCALCPRKYNRKDRLTAHMKKFHNPGGATSQSPAPSKKSSAVAAASSSSIASPKQPKLFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDFCEMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGICGERFIQGTALKNHRLQQGHHEPGIPGGLPGEAPPRRTVLQQFTGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00612227;
90% Identity: iTF_00555983;
80% Identity: -